Portal de investigación
Preeclampsia: a defect in decidualization is associated with deficiency of Annexin A2.
Autores de IIS La Fe
Participantes ajenos a IIS La Fe
- Garrido-Gomez T
- Hajjar KA
- Simon C
Grupos
Abstract
Decidualization defects in the endometrium have been demonstrated at the time of delivery in women with severe preeclampsia (sPE) and linger for years, suggesting a maternal contribution to the pathogenesis of this condition. Global transcriptional profiling reveals alterations in gene expression, including downregulation of Annexin A2 (ANXA2) in sPE patients with decidualization resistance.
Datos de la publicación
- ISSN/ISSNe:
- 0002-9378, 1097-6868
- Tipo:
- Article
- Páginas:
- -
- Factor de Impacto:
- 3,497 SCImago ℠
- Cuartil:
- Q1 SCImago ℠
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY MOSBY-ELSEVIER
Citas Recibidas en Web of Science: 32
Documentos
- No hay documentos
Filiaciones
Keywords
- ANXA2 deficiency, ANXA2-null mice, decidualization resistance, human endometrial stromal cells, placentation defect, severe preeclampsia
Proyectos asociados
Contrato Miguel Servet Tipo II - DOMINGUEZ HERNÁNDEZ, FRANCISCO
Investigador Principal: FRANCISCO DOMÍNGUEZ HERNÁNDEZ
MSII18/00002 . INSTITUTO DE SALUD CARLOS III . 2019
Contrato PFIS: Predoctorales de formación en investigación en salud. Andrea Palomar
Investigador Principal: FRANCISCO DOMÍNGUEZ HERNÁNDEZ
FI18/00009 . INSTITUTO DE SALUD CARLOS III . 2019
Influencia de los disruptores endocrinos sobre la receptividad endometrial humana y su relación con el fallo de impantación y la endometriosis.
Investigador Principal: FRANCISCO DOMÍNGUEZ HERNÁNDEZ
PI17/00931 . INSTITUTO DE SALUD CARLOS III . 2018
Cita
Garrido T,Quiñonero A,Dominguez F,Rubert L,Perales A,Hajjar KA,Simon C. Preeclampsia: a defect in decidualization is associated with deficiency of Annexin A2. Am J Obstet Gynecol. 2020. 222. (4):376.e1-376.e17. IF:8,661. (1).