1. Inicio
  2. Publicaciones
  3. Direct conversion of human fibroblast to hepatocytes using a single inducible polycistronic vector.

Direct conversion of human fibroblast to hepatocytes using a single inducible polycistronic vector.

Fecha de publicación:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Ballester M
  • Santamaria R

Grupos

Abstract

Human fibroblasts can be reprogrammed into induced hepatocyte-like cells through the expression of a set of transcription factors. Although the generation of induced hepatocyte-like cells by HNF4A, HNF1A, and FOXA3 expression has proven to be a robust experimental strategy, using multiple lentivirus results in a highly variable heterogeneous population.

Datos de la publicación

ISSN/ISSNe:
1757-6512, 1757-6512

STEM CELL RESEARCH & THERAPY  BIOMED CENTRAL LTD

Tipo:
Article
Páginas:
317-317
PubMed:
31685034
Factor de Impacto:
1,501 SCImago ℠
Cuartil:
Q1 SCImago ℠

Citas Recibidas en Web of Science: 17

Documentos

  • No hay documentos

Métricas

Filiaciones mostrar / ocultar

Keywords

  • Doxycycline, Induced hepatocyte-like cells, Inducible, Polycistronic vectors, Reprogramming, iHEP

Cita

Compartir