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Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemia

Fecha de publicación:

Autores de IIS La Fe

Participantes ajenos a IIS La Fe

  • Jacob, J
  • Llauger, L
  • Herrero-Puente, P
  • Martin-Sanchez, FJ
  • Llorens, P
  • Gil, V
  • Fuentes, M
  • Miro, O
  • Gil, C
  • Alonso, H
  • Perez-Llantada, E
  • Llopis-Garcia, G
  • Santos-Matallana, MC
  • Barrenechea-Moxo, MLD
  • Salgado-Perez, L
  • Escoda, R
  • Xipell, C
  • Sanchez, C
  • Gaytan, JM
  • Pavon, J
  • Noval, A
  • Torres, JM
  • Lopez-Grima, ML
  • Valero, A
  • Juan, MA
  • Aguirre, A
  • Pedragosa, MA
  • Minguez-Maso, S
  • Alonso, MI
  • Ruiz, F
  • Franco, JM
  • Mecina, AB
  • Tost, J
  • Berenguer, M
  • Donea, R
  • Sanchez-Ramon, S
  • Carbajosa-Rodriguez, V
  • Pinera, P
  • Sanchez-Nicolas, JA
  • Garate, RT
  • Alquezar-Arbe, A
  • Rizzi, MA
  • Herrera, S
  • Roset, A
  • Cabello, I
  • Haro, A
  • Richard, F
  • Alvarez-Perez, JM
  • Lopez-Diez, MP
  • Vazquez-Alvarez, J
  • Prieto-Garcia, B
  • Garcia, MG
  • Gonzalez, MS
  • Javaloyes, P
  • Marquina, V
  • Jimenez, I
  • Hernandez, N
  • Brouzet, B
  • Espinosa, B
  • Andueza, JA
  • Romero, R
  • Ruiz, M
  • Calvache, R
  • Serralta, MTL
  • Javez, LEC
  • Arriaga, BA
  • Bergua, BS
  • Mojarro, EM
  • Jimenez, BSA
  • Becquer, LT
  • Burillo, G
  • Garcia, LL
  • LaSalle, GC
  • Urbano, CA
  • Soto, ABG
  • Padial, ED
  • Ferrer, ES
  • Garrido, JM
  • Lucas-Imbernon, FJ
  • Gaya, R
  • Bibiano, C
  • Mir, M
  • Rodriguez, B
  • Carballo, JL
  • Rodriguez-Adrada, E
  • Miranda, BR
  • ICASEMES-Res Grp

Grupos

Abstract

Objective: To study the outcomes of patients with acute heart failure (AHF) presenting renal dysfunction (RD) or hyperkalaemia (Hk) alone or in combination. Method: We analysed the data of the EAHFE registry, a multicentre, non interventionist cohort with prospective follow-up of patients with AHF. Four groups were defined based on the presence or not of RD or Hk alone or in combination. The primary endpoint was 30-day all-cause mortality. Results: A total of 11,935 of the 13,791 patients included in the EAHFE registry were analysed. Of these, 5088 (42.6%) did not have RD or Hk (NoRD-NoHk), 150 (1.3%) had no RD but had Hk (NoRD-Hk), 6012 (50.4%) had RD but not Hk (RD-NoHk) and 685 (5.7%) had both RD and Hk (RD-Hk). Thirty-day all-cause mortality was greatest in the RD-Hk group with an adjusted Hazard Ratio (HR) of 2.44 (confidence interval 95% [C195%] 1.67-3.55; p < 0.001) and in the RD-NoHk group with an adjusted HR of 1.34 (CI95% 1.04-1.71; p = 0.022). There were no significant differences in in-hospital mortality and reconsultation at 30 days for HF. For the combined endpoint of 30-day all-cause mortality the adjusted HR was 1.33 (CI95% 1.04-1.70); (p = 0.021) for the RD-Hk group. Conclusions: The association of 30-day all-cause mortality with the presence of RD and Hk in patients presenting AHF at admission is greater than in those without this combination.

Datos de la publicación

ISSN/ISSNe:
0953-6205, 1879-0828

EUROPEAN JOURNAL OF INTERNAL MEDICINE  ELSEVIER SCIENCE BV

Tipo:
Article
Páginas:
89-96
PubMed:
31331793
Factor de Impacto:
1,017 SCImago ℠
Cuartil:
Q2 SCImago ℠

Citas Recibidas en Web of Science: 3

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Keywords

  • Acute heart failure; Renal dysfunction; Hyperkalaemia; Outcomes

Campos de Estudio

Proyectos y Estudios Clínicos

PRAGMATIC, CONTROLLED, INTERNATIONAL STUDY CONDUCTED IN SEVERAL CENTRES ON THE SAFETY AND THERAPEUTIC EFFECT OF A HYDROXYLETHYL-STARCH (HES) SOLUTION VERSUS AN ELECTROLYTE SOLUTION IN TRAUMA PATIENTS.

Investigador Principal: ÓSCAR DÍAZ CAMBRONERO

HC-G-H-1505 . 2018

EFECTO DE V0251 EN EL VÉRTIGO AGUDO. ESTUDIO ALEATORIZADO, DOBLE CIEGO Y CONTROLADO CON PLACEBO.

Investigador Principal: HERMINIO PÉREZ GARRIGUES

V00251IV2024A

PERFIL DE RIESGO DE LOS PACIENTES CON ETV EN HOSPITALES ESPAÑOLES ATENDIDOS EN LOS SERVICIOS DE URGENCIAS E IMPACTO ASISTENCIAL: REGISTRO ESPHERIA.

Investigador Principal: MARÍA JOSÉ PÉREZ DURÁ

ESPHERIA

PLANIFICACIÓN DEL ALTA DESDE URGENCIAS PARA REDUCIR REINGRESOS A 30 DÍAS EN MAYORES FRÁGILES CON INSUFICIENCIA CARDÍACA AGUDA: ENSAYO CLÍNICO ALEATORIZADO POR CONGLOMERADOS PAREADO.

Investigador Principal: CARMEN GARGALLO MAICAS

DEED FRAIL-AHF . 2019

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