Anterior Segment Biometry and Their Correlation with Corneal Biomechanics in Caucasian Children

Data de publicació: 01/02/2019

Autors de IIS La Fe

Enrique España Gregori

Autor

Autors aliens a IIS La Fe

Bueno-Gimeno, I
Martinez-Albert, N
Gene-Sampedro, A

Grups d'Investigació

Investigación en Neuroinmunología y Esclerosis Múltiple

Leader

Bonaventura Casanova Estruch

Abstract

Purpose: To assess the relationship between the corneal biomechanical parameters and the anterior segment parameters in Caucasian children. Methods: This study included 293 eyes from 293 healthy children aged between 6 and 17 years. Corneal hysteresis (CH) and corneal resistance factor (CRF) were evaluated with the Ocular Response Analyzer, axial length (AL) with IOLMaster and the anterior segment with Pentacam. Anterior segment parameters obtained were the following: central corneal thickness (CCT), corneal volume (CV), anterior chamber depth (ACD), anterior chamber volume (ACV) and mean anterior and posterior keratometry. Two multiple linear regression models were constructed to assess the association between CH and CRF with anterior segment parameters. A value of p < 0.05 was taken as the criterion for statistical significance in all analyses. Results: The mean CH and CRF were 12.12 +/- 1.71 and 12.30 +/- 1.89 mmHg, respectively. Multiple linear regression revealed that CH and CRF were associated negatively with AL in both models, and positively with CCT and CV in the first and second model, respectively. Meanwhile ACD, ACV or mean keratometry did not correlated with CH and CRF. Moreover, when CCT was in the model, it explained more variability for both CH (22.1%) and CRF (30.9%) than when CV was included (16.2% for CH and 16.5% for CRF). Conclusions: CH and CRF were correlated positively with CCT and CV, and negatively with AL in healthy Caucasian children. Moreover, corneal parameters were the most contributory variables to CH and CRF changes.

Dades de la publicació

ISSN/ISSNe:: 0271-3683, 1460-2202
Tipus:: Article
Pàgines:: 118-124
DOI:: 10.1080/02713683.2018.1539181
PubMed:: 30346843
Factor d'Impacte:: 0,822 SCImago ℠
Quartil:: Q2 SCImago ℠

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Keywords

Corneal biomechanics; ocular response analyzer; anterior ocular segment; children

Projectes associats

PATRONES DE RM CEREBRAL Y MEDULAR EN RELACION CON LA PRESENCIA DE AUTOANTIGENOS NEURONALES RECONOCIDOS POR INMUNOGLOBULINAS M PRESENTES EN EL LIQUIDO CEFALORRAQUIDEO DE PACIENTES DE ESCLEROSIS MULTIPLE.

Investigador Principal: ISABEL BOSCÁ BLASCO

MERCK SERONO DR. CASANOVA . ALMIRALL S.A; FUNDACIÓN BIOGEN IDEC; MERCK S.L.U; FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA . 2010