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- Projectes i Estudis Clínics
- Estudio de prueba de concepto y búsqueda de dosis, multicéntrico, aleatorizado, con control activo y placebo, de grupos paralelos y de 24 semanas de duración en el que se evalúan la eficacia, la seguridad y la tolerabilidad de XXB750 en pacientes con insuficiencia cardíaca.
Estudio de prueba de concepto y búsqueda de dosis, multicéntrico, aleatorizado, con control activo y placebo, de grupos paralelos y de 24 semanas de duración en el que se evalúan la eficacia, la seguridad y la tolerabilidad de XXB750 en pacientes con insuficiencia cardíaca.
Dades bàsiques
- Protocol:
- CXXB750A12201
- EURDRACT:
- NCT:
- Centre:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Any inici:
- 2024
- Any de finalització:
Documents
- No hi ha documents
Participants
Grups d'Investigació
Finançadors - Promotors
Resultats de l'Assaig Clínic
[[en]]Peripheral access ultrafiltration in adults with complex congenital heart disease and refractory congestion.
Guerrero Cervera B; (...); Almenar Bonet L
Article. 10.1016/j.rec.2024.08.015. 2024
[Translated article] Knowledge of biological therapy in patients with immune-mediated diseases. BIOINFO study.
Segui-Solanes, Carlos; (...); Borras-Blasco, Joaquin
Article. 10.1016/j.farma.2024.08.002. 2024
[Translated article] New challenges in advanced therapies.
Megías-Vericat JE; (...); Poveda Andrés JL
Article. 10.1016/j.farma.2024.05.001. 2024
[Translated article] Pharmacokinetic-guided switching from standard half-life factor VIII to extended half-life pegylated factor VIII in haemophilia A therapy in clinical practice.
Chovi-Trull, Maria; (...); Andres, Jose Luis Poveda
Article. 10.1016/j.farma.2024.12.007. 2025
Analysis of complications in patients with ECMO as a bridge to transplantation since the beginning of the technique (2007-2023)
Guerrero Cervera, Borja; (...); Almenar Bonet, Luis
Meeting Abstract. 2024
Annual evolution of the prescription of drugs with prognostic implications in acute decompensated heart failure with reduced ejection fraction.
López-Vilella R; (...); Almenar Bonet L
Article. 10.1186/s12872-024-03728-y. 2024
Benefits of physical activity self-monitoring in patients with haemophilia: a prospective study with one-year follow-up.
Pérez-Alenda S; (...); Núñez-Cortés R
Article. 10.1111/hae.14988. 2024
Clinical profile of an unselected population with heart failure treated with vericiguat in real life: differences with the VICTORIA trial
Esteban-Fernandez, Alberto; (...); VERISEC Registry Researchers
Article. 10.3389/fcvm.2024.1504427. 2025
Clinical profile of heart failure patients starting vericiguat in clinical practice
Esteban Fernandez, A. Alberto; (...); Diez Villanueva, P.
Meeting Abstract. 2024
Clinical profiling of patients admitted with acute heart failure: a comprehensive survival analysis.
Lopez-Vilella, Raquel; (...); Almenar Bonet, Luis
Article. 10.3389/fcvm.2024.1381514. 2024
Clinical utility and safety of finerenone in patients with heart failure: Rationale and design of FINE registry.
Alonso Salinas, Gonzalo Luis; (...); Diez-Villanueva, Pablo
Article. 10.1002/ehf2.15260. 2025
Clinical, echocardiographic and analytical patterns of biomarkers in cardiac amyloidosis; a real-world analysis.
Lopez Vilella, R. Raquel; (...); Almenar Bonet, L.
Meeting Abstract. 2024
Comparative Temporal Analysis of Morbidity and Early Mortality in Heart Transplantation with Extracorporeal Membrane Oxygenation Support: Exploring Trends over Time
Lopez-Vilella, Raquel; (...); Bonet, Luis Almenar
Article. 10.3390/biomedicines12092109. 2024
Comprehensive survival analysis in acute heart failure: profiling patients through clinical examination at admission
Raquel Lopez Vilella, R.; (...); Almenar Bonet, L.
Meeting Abstract. 2024
Cost-effectiveness and cost-utility analysis of haemate-P versus other von willebrand disease treatments in Spain.
Megias-Vericat, Juan E; (...); Yan, Songkai
Article. 10.1080/13696998.2025.2474886. 2025
Destination Therapy Strategies of Advanced Heart Failure in Elderly Non-Heart Transplant Candidates: A Propensity Matching Analysis from the LEVO-D and REGALAD Registries
Dobarro, David; (...); Gonzalez-Costello, Jose
Article. 10.3390/life14121570. 2024
Development and testing of a mobile app for systematic collection of patient-reported outcomes (PROs) in patients with hemophilia.
Megias-Vericat, J E; (...); Poveda Andres, J L
Letter. 10.1016/j.thromres.2024.109122. 2024
Donor-derived cell-free DNA as a new biomarker for cardiac allograft rejection: A prospective study (FreeDNA-CAR).
Jimenez-Blanco, Marta; (...); Segovia-Cubero, Javier
Article. 10.1016/j.healun.2024.11.009. 2024
Facilitators and barriers to perform physical activity in patients post-heart transplantation: a qualitative study.
Klompstra L; (...); Marques-Sule E
Article. 10.1093/eurjcn/zvae144. 2024
Impact of left ventricular unloading on postheart transplantation outcomes in patients bridged with VA-ECMO.
Enríquez-Vázquez D; (...); Crespo-Leiro MG
Article. 10.1016/j.rec.2024.09.005. 2024
Impact of preoperative left ventricular unloading on post-transplant outcomes of candidates bridged with venoarterial extracorporeal membrane oxygenation
Enriquez Vazquez, D.; (...); Crespo-Leiro, M.
Meeting Abstract. 2024
Impact on Survival of Heart and Heart-Lung Transplantation in Patients With Cyanotic and Noncyanotic Congenital Heart Diseases.
Donoso-Trenado, Victor; (...); Almenar-bonet, Luis
Article. 10.1016/j.transproceed.2024.12.005. 2024
Implications of Molecular Markers in Brain-Dead Donors in Primary Graft Dysfunction and Rejection After Heart Transplantation: The Potential Role of Preconditioning
Herrador-Galindo, L.; (...); Moreno-Gonzalez, G.
Meeting Abstract. 10.1016/j.healun.2024.02.526. 2024
Improvement in left atrial strain following ferric carboxymaltose in heart failure: an analysis of the Myocardial-IRON trial.
Santas E; (...); Núñez J
Article. 10.1002/ehf2.14630. 2023
Lower heart rate in patients with acute heart failure: the role of left ventricular ejection fraction
Lorenzo, Miguel; (...); Nunez, Julio
Article. 10.1080/14017431.2024.2386977. 2024
Mental, emotional and social dimensions of quality of life and their relationship with physical and functional status in adults with haemophilia.
Rodríguez MA; (...); Chimeno-Hernández A
Article. 10.1016/j.thromres.2024.109181. 2024
Multicenter Clinical Trial to Evaluate the Efficacy of a Preventive Strategy Against Cytomegalovirus Infection in Heart Transplant Patients Based on the Specific T Cells Response
Garcia-Romero, E.; (...); Gonzalez-Costello, J.
Meeting Abstract. 2024
New challenges of advanced therapies.
Megías-Vericat JE; (...); Poveda Andrés JL
Article. 10.1016/j.farma.2023.11.008. 2024
No Obesity Paradox for Health-Related Quality of Life in Patients with Heart Failure and Reduced Ejection Fraction: Insights from the VIDA Multicenter Study
Cassado-Valls, Paula; (...); Comin-Colet, Josep
Article. 10.3390/jcm13247558. 2024
Particularities of foundational therapy in patients with newly diagnosed heart failure and reduced LVEF secondary to tachycardiomyopathy
Esteban Fernandez, A. Alberto; (...); De Juan Baguda, J.
Meeting Abstract. 2024
Pharmacogenetics in Response to Biological Agents in Inflammatory Bowel Disease: A Systematic Review.
Ballesta-Lopez, Octavio; (...); Poveda-Andres, Jose Luis
Article. 10.3390/ijms26041760. 2025
Practical Requirements for the Development of an Advanced Cardiorenal Unit
Almenar-Bonet, Luis; (...); Sanchez-Perez, Pilar
Review. 10.1159/000536104. 2024
Predicting Sarcopenia and Frailty Risk in Patients Post Heart Transplantation.
Sentandreu-Mano, Trinidad; (...); Machado, Felipe V C
Article. 10.1111/ctr.70027. 2025
Prevalence, characteristics, and phenotype associated with tachycardiomyopathy in a cohort of patients first hospitalized for heart failure with reduced ejection fraction
Otero Garcia, O.; (...); Gonzalez-Juanatey, J. R.
Meeting Abstract. 2024
Prognostic determinants in patients with heart failure with reduced ejection fraction after a first hospitalisation for acute heart failure. COMFE registry
Vega, D. Garcia; (...); Gonzalez-Juanatey, J. R.
Meeting Abstract. 10.1093/eurheartj/ehae666.1187. 2024
Prognostic determinants in patients with heart failure with reduced ejection fraction after a first hospitalisation for acute heart failure. implications for their clinical management. COMFE registry
Garcia Vega, D. David; (...); Gonzalez-Juanatey, J. R.
Meeting Abstract. https://doi.org/10.1093/eurheartj/ehae666.1187. 2024
Relaxin mimetic in pulmonary hypertension associated with left heart disease: Design and rationale of Re-PHIRE.
Ufnal, Marcin; (...); Rosenkranz, Stephan
Article. 10.1002/ehf2.15203. 2025
Role of spot urinary sodium in outpatients with heart failure.
Lorenzo, Miguel; (...); Nunez, Julio
Article. 10.1016/j.rec.2024.07.002. 2024
Sinus rhythm restoration as an independent predictor of left ventricular ejection fraction improvement in patients with the first hospitalization for heart failure and reduced ejection fraction
Otero Garcia, O. Oscar; (...); Gonzalez-Juanatey, J. R.
Meeting Abstract. https://doi.org/10.1093/eurheartj/ehae666.836. 2024
Sinus rhythm restoration as an independent predictor of left ventricular ejection fraction improvement in patients with the first hospitalization for heart failure and reduced ejection fraction
Garcia, O. Otero; (...); Gonzalez-Juanatey, J. R.
Meeting Abstract. 10.1093/eurheartj/ehae666.836. 2024
Spanish heart transplant registry. 35th official report of the Heart Failure Association of the Spanish Society of Cardiology.
González-Vílchez F; (...); García-Romero E
Article. 10.1016/j.rec.2024.05.015. 2024
Spot urinary sodium in outpatients with chronic heart failure. A longitudinal analysis
Lorenzo Hernandez, M. Miguel; (...); Nunez, J.
Meeting Abstract. 2024
Structural heart transcatheter interventions in orthotopic cardiac transplant and left ventricular assist devices recipients: A nationwide study.
Blasco-Turrion, Sara; (...); Amat-Santos, Ignacio J.
Article. 10.1016/j.ijcard.2024.132340. 2024
Toxic-metabolic encephalopathy induced by metronidazole and disulfiram: classics never die.
Chovi-Trull, Maria; (...); Poveda-Andres, Jose Luis
Article. 10.1136/ejhpharm-2024-004184. 2024
Unveiling the prognostic journey: renal function trajectories in 'de novo' heart failure with reduced ejection fraction - insights from a cohort study and their impact on patient outcomes
Garcia, O. Otero; (...); Gonzalez-Juanatey, J. R.
Meeting Abstract. 10.1093/eurheartj/ehae666.835. 2024
Usefulness of biomarkers to predict prognosis after heart transplant
Lopez-Vilella, Raquel; (...); Boneta, Luis Almenar
Article. 10.1016/j.rec.2024.04.019. 2024
What clinical parameters are associated with the prescription at hospital discharge of all medications with prognostic improvement? Analysis in de novo heart failure with reduced ejection fraction
Lopez Vilella, R. Raquel; (...); Bonet, Almenar
Meeting Abstract. 2024
What factors are associated with myocardial recovery following admission for acute heart failure? Study in patients with de novo diagnosis and reduced left ventricular ejection fraction
Donoso Trenado, V.; (...); Almenar-Bonet, L.
Meeting Abstract. 2024