ADN tumoral circulante como predictor de recaída en pacientes con cáncer de recto localmente avanzado tratados con terapia neoadyuvante total seguida de observación y espera o escisión total del mesorrecto basada en la evaluación clínica de la respuesta.

Datos básicos

Protocolo:
GEMCAD 2201
EUDRACT:
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Año de incio:
2023
Año de finalización:
PI BIOMÉDICA

Documentos

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Participantes

Grupos

Financiadores - Promotores

GRUPO ESPAÑOL MULTIDI EN CANCER DIGE. GEMCAD

Resultados del Ensayo Clínico


An exosome-based liquid biopsy predicts depth of response and survival outcomes to cetuximab and panitumumab in metastatic colorectal cancer: The EXONERATE Study.

Xu, Caiming; (...); Goel, Ajay

Article. 10.1158/1078-0432.CCR-24-1934. 2025


Correction: Update on the management of elderly patients with colorectal cancer.

Soler-González G; (...); Gironés-Sarrió R

Correction. 10.1007/s12094-023-03351-x. 2024

  • Open Access.

Development of a predictive model of venous thromboembolism recurrence in anticoagulated cancer patients using machine learning.

Munoz, Andres J.; (...); Hernandez-Presa, Miguel Angel

Article. 10.1016/j.thromres.2023.06.015. 2023


Dynamic nature of BRAF or KRAS p.G12C mutations in second-line therapy for advanced colorectal cancer patients: do early and late effects exist?

Contreras-Toledo, Debora; (...); Carmona-Bayonas, Alberto

Article. 10.1038/s41416-023-02563-w. 2024


Encorafenib (E) plus binimetinib (B) in unresectable advanced or metastatic BRAFV600-mut melanoma, real-world evidence in Spain (GEM 2002-BECARE)

Soria, A.; (...); Cerezuela-Fuentes, P.

Meeting Abstract. 10.1016/j.annonc.2023.09.2248. 2023

  • Open Access.

Encorafenib and binimetinib followed by radiotherapy for patients with BRAFV600-mutant melanoma and brain metastases (E-BRAIN/GEM1802 phase II study).

Marquez-Rodas, Ivan; (...); Berrocal, Alfonso

Article. 10.1093/neuonc/noae116. 2024

  • Open Access.

First in human trial of CEB-01 for retroperitoneal soft tissue sarcoma

Gonzalez, J. A.; (...); Lopez Pousa, A.

Meeting Abstract. 10.1016/j.annonc.2023.09.1161. 2023

  • Open Access.

First-in-human CEB-01: Novel loco-regional SN-38 release membrane to prevent local recurrence in retroperitoneal sarcomas

Gonzalez-Lopez, Jose Antonio; (...); Pousa, Antonio Lopez

Meeting Abstract. https://doi.org/10.1016/j.annonc.2023.09.1161. 2024

  • Open Access.

First-line chemotherapy with or without targeted therapies in metastatic colorectal cancer: The GEMCAD 14-01 prospective cohort

Oliveres, H.; (...); Maurel, J.

Meeting Abstract. 10.1016/j.annonc.2023.09.1796. 2023


Hypertension as predictive factor for bevacizumab-containing first-line therapy in metastatic breast and colorectal cancer in BRECOL (GEICAM/2011-04) study.

Rodríguez-Lescure Á; (...); de la Haba-Rodriguez J

Article. 10.1007/s12094-024-03411-w. 2024

  • Open Access.

Multicenter real-world data of treatment with NALIRI plus 5FU/LV in advanced Spanish pancreatic cancer

Alvarez Gallego, R.; (...); Cubillo, A.

Meeting Abstract. 10.1016/j.annonc.2023.04.238. 2023


Neoadjuvant Chemotherapy in High-Grade Myxoid Liposarcoma: Results of the Expanded Cohort of a Randomized Trial From Italian (ISG), Spanish (GEIS), French (FSG), and Polish Sarcoma Groups (PSG).

Gronchi, Alessandro; (...); Casali, Paolo Giovanni

Article. 10.1200/JCO.23.00908. 2024


Pharmacogenetics of Neoadjuvant MAP Chemotherapy in Localized Osteosarcoma: A Study Based on Data from the GEIS-33 Protocol

Salazar, Juliana; (...); Sebio, Ana

Article. 10.3390/pharmaceutics16121585. 2024

  • Open Access.

Phase Ib Study for the Combination of Doxorubicin, Dacarbazine, and Nivolumab as the Upfront Treatment in Patients With Advanced Leiomyosarcoma: A Study by the Spanish Sarcoma Group (GEIS).

Martin-Broto J; (...); Hindi N

Article. 10.1200/JCO.24.00358. 2024


Precision medicine in metastatic colorectal cancer: targeting KRAS G12C mutation

Aparicio, Jorge

Article. 10.21037/tgh-24-28. 2024

  • Open Access.

Prediction model for major bleeding in anticoagulated patients with cancer-associated venous thromboembolism using machine learning and natural language processing.

Munoz Martin, Andres J; (...); Hernandez-Presa, Miguel Angel

Article. 10.1007/s12094-024-03586-2. 2024

  • Open Access.

Prognostic Factor Risk Groups for Clinical Stage I Seminoma: An Individual Patient Data Analysis by the European Association of Urology Testicular Cancer Guidelines Panel and Guidelines Office.

Boormans, Joost L; (...); Laguna, M Pilar

Article. 10.1016/j.euo.2023.10.014. 2023


Real-world dosing patterns of regorafenib for patients with metastatic colorectal cancer in Spain: the RE-SEARCH study.

López Muñoz AM; (...); Martín Gómez T

Article. 10.1007/s12094-024-03630-1. 2024


Real-world effectiveness and safety of second- or third-line pegylated liposomal irinotecan plus 5-fluorouracil and folinic acid in pancreatic ductal adenocarcinoma in Spain

Alvarez-Gallego, Rafael; (...); Cubillo, Antonio

Article. 10.1177/17588359241309828. 2025

  • Open Access.

Redefining radiologic responses (RR) in solid tumors: Shall we brace ourselves for a post-RECIST era? Results from a randomized clinical trial (RCT) on neoadjuvant chemotherapy in high-risk soft-tissue sarcomas (HR-STS) of the trunk or extremities

Vanzulli, Andrea; (...); Gronchi, Alessandro

Meeting Abstract. https://doi.org/10.1200/JCO.2024.42.16_suppl.11553. 2024

  • Open Access.

Redefining radiologic responses in high-risk soft-tissue sarcomas treated with neoadjuvant chemotherapy: final results of ISG-STS 1001, a randomized clinical trial.

Vanzulli, A; (...); Gronchi, A

Article. 10.1016/j.esmoop.2025.104299. 2025

  • Open Access.

Retrospective real-world data study using natural language processing to describe treatment sequence and clinicopathological patterns in patients with metastatic colorectal cancer in five Spanish institutions

Vera Garcia, R.; (...); Mondejar Solis, R.

Meeting Abstract. 10.1016/j.annonc.2023.04.343. 2023

  • Open Access.

SEOM-GG clinical guidelines for the management of germ-cell testicular cancer (2023).

Arranz Arija, Jose Angel; (...); Gonzalez-Billalabeitia, Enrique

Article. 10.1007/s12094-024-03532-2. 2024

  • Open Access.

Sequential RAS mutations evaluation in cell-free DNA of patients with tissue RAS wild-type metastatic colorectal cancer: the PERSEIDA (Cohort 2) study.

Valladares-Ayerbes M; (...); Lloansí Vila A

Article. 10.1007/s12094-024-03487-4. 2024

  • Open Access.

Spatial distribution of tumour immune infiltrate predicts outcomes of patients with high-risk soft tissue sarcomas after neoadjuvant chemotherapy.

Pasquali, Sandro; (...); Gronchi, Alessandro

Article. 10.1016/j.ebiom.2024.105220. 2024

  • Open Access.

Update on the management of elderly patients with colorectal cancer.

Soler-Gonzalez, Gemma; (...); Girones-Sarrio, Regina

Article. 10.1007/s12094-023-03243-0. 2023

  • Open Access.

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