NUEVOS SISTEMAS DE DIAGNÓSTICO Y TRATAMIENTO BASADOS EN QUÍMICA SUPRAMOLECULAR Y NANOTECNOLOGÍA

Dades bàsiques

Protocol:
INVEST/2023/443
EURDRACT:
NCT:
Centre:
Any inici:
2023
Any de finalització:
2025
RRHH AUTONÓMICO Finan. Competitiva Pública 132.436,00 €

Documents

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Participants

Grups d'Investigació

Finançadors - Promotors

CONSELLERIA DE INNOVACIÓN, UNIVERSIDADES, CIENCIA Y SOCIEDAD DIGITAL

Resultats de l'Assaig Clínic


A navitoclax-loaded nanodevice targeting matrix metalloproteinase-3 for the selective elimination of senescent cells.

Escriche-Navarro, Blanca; (...); Martinez-Manez, Ramon

Article. 10.1016/j.actbio.2024.01.002. 2024

  • Open Access.

A renal clearable fluorogenic probe for in vivo beta-galactosidase activity detection during aging and senolysis.

Rojas-Vazquez, Sara; (...); Martinez-Manez, Ramon

Article. 10.1038/s41467-024-44903-1. 2024

  • Open Access.

Advancements in 3D bioprinting for nanoparticle evaluation:Techniques, models, and biological applications

Yoon, Moon Sup; (...); Shin, Dae Hwan

Review. 10.36922/ijb.4273. 2024

  • Open Access.

beta-Galactosidase-Triggered Photodynamic Elimination of Senescent Cells with a Boron Dipyrromethene-Based Photosensitizer.

Chu, Jacky C H; (...); Ng, Dennis K P

Article. 10.1002/advs.202401012. 2024

  • Open Access.

Comparing organic and metallo-organic hydrazone molecular cages as potential carriers for doxorubicin delivery.

Monta-Gonzalez, Giovanni; (...); Marti-Centelles, Vicente

Article. 10.1039/d4sc02294g. 2024

  • Open Access.

Chemical Strategies for the Detection and Elimination of Senescent Cells.

Garcia-Fleitas, Jessie; (...); Martinez-Manez, Ramon

Article. 10.1021/acs.accounts.3c00794. 2024

  • Open Access.

Detection and Elimination of Senescent Cells with a Self-Assembled Senescence-Associated ß-Galactosidase-Activatable Nanophotosensitizer.

Chu JCH; (...); Ng DKP

Article. 10.1021/acs.jmedchem.3c01306. 2023

  • Open Access.

Exploring the Synergy between Nano-Formulated Linezolid and Polymyxin B as a Gram-Negative Effective Antibiotic Delivery System Based on Mesoporous Silica Nanoparticles

Otri, Ismael; (...); Sancenon, Felix

Article. 10.3390/nano14020228. 2024

  • Open Access.

Metabolomic study for the identification of symptomatic carotid plaque biomarkers

Botello-Marabotto, Marina; (...); Miralles, Manuel

Article. 10.1016/j.talanta.2024.127211. 2025

  • Open Access.

Models of Chemical Communication for Micro/Nanoparticles.

Ventura, Jordi; (...); Martinez-Manez, Ramon

Article. 10.1021/acs.accounts.3c00619. 2024

  • Open Access.

Nanodevice-Mediated Immune Cell Recruitment: Targeting Senescent Cells via MMP-3-Responsive CXCL12-Coated Nanoparticles.

Escriche-Navarro, Blanca; (...); Martinez-Manez, Ramon

Article. 10.1021/acsami.4c17748. 2025


Nitroreductase-responsive gated mesoporous silica nanocarriers for hypoxia-targeted drug delivery

Barros, Mariana; (...); Gavina, Pablo

Article. 10.1016/j.ijpharm.2025.125326. 2025


Remarkable enhancement of cinnamaldehyde antimicrobial activity encapsulated in capped mesoporous nanoparticles: A new "nanokiller" approach in the era of antimicrobial resistance.

Morellá-Aucejo Á; (...); Bernardos A

Article. 10.1016/j.bioadv.2024.213840. 2024

  • Open Access.

Renal-clearable probes for disease detection and monitoring.

Dominguez, Marcia; (...); Martinez-Manez, Ramon

Article. 10.1016/j.tibtech.2024.11.020. 2024


SARS-CoV-2 N protein IgG antibody detection employing nanoporous anodized alumina: A rapid and selective alternative for identifying naturally infected individuals in populations vaccinated with spike protein (S)-based vaccines

Esteve-Sanchez, Yoel; (...); Climent, Estela

Article. 10.1016/j.snb.2024.136378. 2024

  • Open Access.

SARS-COV-2 viral RNA detection through oligonucleotide-capped nanoporous anodic alumina supports.

Lopez-Palacios, Alba; (...); Climent, Estela

Article. 10.1016/j.snr.2025.100298. 2025


Self-propelled enzyme-controlled IR-mesoporous silica Janus nanomotor for smart delivery

Mayol, Beatriz; (...); Villalonga, Reynaldo

Article. 10.1016/j.jcis.2024.05.134. 2024


Superior Live Birth Rates, Reducing Sperm DNA Fragmentation (SDF), and Lowering Miscarriage Rates by Using Testicular Sperm Versus Ejaculates in Intracytoplasmic Sperm Injection (ICSI) Cycles from Couples with High SDF: A Systematic Review and Meta-Analysis

Cano-Extremera, Marina; (...); Puchalt, Nicolas Garrido

Review. 10.3390/biology14020130. 2025


Synergistic antimicrobial photodynamic therapy using gated mesoporous silica nanoparticles containing curcumin and polymyxin B.

Medaglia, Serena; (...); Martinez-Manez, Ramon

Article. 10.1016/j.ijpharm.2024.123947. 2024

  • Open Access.

Synthesis of a Pd2L4 Hydrazone Molecular Cage Through Multiple Reaction Pathways

Monta-Gonzalez, Giovanni, Martinez-Manez, Ramon, Marti-Centelles, Vicente

Article. 10.3390/ijms252211861. 2024

  • Open Access.

Systematic study of the implications of calcination and solvent extraction of the surfactant in MCM-41-type mesoporous silica nanoparticles

Candela-Noguera, Vicente; (...); Martinez-Manez, Ramon

Article. 10.1016/j.micromeso.2024.113119. 2024

  • Open Access.

Tear metabolomics for the diagnosis of primary open-angle glaucoma.

Botello-Marabotto M; (...); Martínez-Máñez R

Article. 10.1016/j.talanta.2024.125826. 2024

  • Open Access.

Water-Soluble Molecular Cages for Biological Applications

Monta-Gonzalez, Giovanni; (...); Marti-Centelles, Vicente

Review. 10.3390/molecules29071621. 2024

  • Open Access.

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