Portal de investigación
Detección de patología cardiovascular en sangre con puertas moleculares del microRNA-4732-3p: una herramienta innovadora. (ACRÓNIMO GATE-4732-3p)
Datos básicos
- Protocolo:
- DTS23/00017
- EUDRACT:
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Año de incio:
- 2024
- Año de finalización:
- 2027
Documentos
- No hay documentos
Participantes
Grupos
Financiadores - Promotores
Resultados del Ensayo Clínico
A navitoclax-loaded nanodevice targeting matrix metalloproteinase-3 for the selective elimination of senescent cells.
Escriche-Navarro, Blanca; (...); Martinez-Manez, Ramon
Article. 10.1016/j.actbio.2024.01.002. 2024
A renal clearable fluorogenic probe for in vivo beta-galactosidase activity detection during aging and senolysis.
Rojas-Vazquez, Sara; (...); Martinez-Manez, Ramon
Article. 10.1038/s41467-024-44903-1. 2024
Ability of antigen carbohydrate 125 for diagnosis of heart failure with preserved ejection fraction
De Juan Baguda, J. Javier; (...); Delgado Jimenez, J. F.
Meeting Abstract. 2024
Advancements in 3D bioprinting for nanoparticle evaluation:Techniques, models, and biological applications
Yoon, Moon Sup; (...); Shin, Dae Hwan
Review. 10.36922/ijb.4273. 2024
Alterations in Mitochondrial Oxidative Phosphorylation System: Relationship of Complex V and Cardiac Dysfunction in Human Heart Failure
Gimenez-Escamilla, Isaac; (...); Rosello-Lleti, Esther
Article. 10.3390/antiox13030285. 2024
Analysis of complications in patients with ECMO as a bridge to transplantation since the beginning of the technique (2007-2023)
Guerrero Cervera, Borja; (...); Almenar Bonet, Luis
Meeting Abstract. 2024
Annual evolution of the prescription of drugs with prognostic implications in acute decompensated heart failure with reduced ejection fraction.
López-Vilella R; (...); Almenar Bonet L
Article. 10.1186/s12872-024-03728-y. 2024
Atezolizumab Combined With Platinum and Maintenance Niraparib for Recurrent Ovarian Cancer With a Platinum-Free Interval >6 Months: ENGOT-OV41/GEICO 69-O/ANITA Phase III Trial.
Gonzalez-Martin, Antonio; (...); Selle, Frederic
Article. 10.1200/JCO.24.00668. 2024
beta-Galactosidase-Triggered Photodynamic Elimination of Senescent Cells with a Boron Dipyrromethene-Based Photosensitizer.
Chu, Jacky C H; (...); Ng, Dennis K P
Article. 10.1002/advs.202401012. 2024
Circulating long non-coding RNAs detection after heart transplantation and its accuracy in the diagnosis of acute cardiac rejection.
Pérez-Carrillo L; (...); Roselló-Lletí E
Letter. 10.1186/s40364-024-00590-0. 2024
Clinical profiling of patients admitted with acute heart failure: a comprehensive survival analysis.
Lopez-Vilella, Raquel; (...); Almenar Bonet, Luis
Article. 10.3389/fcvm.2024.1381514. 2024
Clinical, echocardiographic and analytical patterns of biomarkers in cardiac amyloidosis; a real-world analysis.
Lopez Vilella, R. Raquel; (...); Almenar Bonet, L.
Meeting Abstract. 2024
Comparative Temporal Analysis of Morbidity and Early Mortality in Heart Transplantation with Extracorporeal Membrane Oxygenation Support: Exploring Trends over Time
Lopez-Vilella, Raquel; (...); Bonet, Luis Almenar
Article. 10.3390/biomedicines12092109. 2024
Comparing organic and metallo-organic hydrazone molecular cages as potential carriers for doxorubicin delivery.
Monta-Gonzalez, Giovanni; (...); Marti-Centelles, Vicente
Article. 10.1039/d4sc02294g. 2024
Comprehensive survival analysis in acute heart failure: profiling patients through clinical examination at admission
Raquel Lopez Vilella, R.; (...); Almenar Bonet, L.
Meeting Abstract. 2024
Culprit-Lesion Drug-Coated-Balloon Percutaneous Coronary Intervention in Patients Presenting with ST-Elevation Myocardial Infarction (STEMI)
Sanz-Sanchez, Jorge; (...); Santos, Ignacio Amat
Article. 10.3390/jcm14030869. 2025
Changes in human skin composition due to intrinsic aging: a histologic and morphometric study.
Arnal-Forne, Marta; (...); Ruiz-Sauri, Amparo
Article. 10.1007/s00418-024-02305-w. 2024
Chemical Strategies for the Detection and Elimination of Senescent Cells.
Garcia-Fleitas, Jessie; (...); Martinez-Manez, Ramon
Article. 10.1021/acs.accounts.3c00794. 2024
Does Fractional Flow Reserve Impact on Clinical Outcomes? Findings From a Systematic Review (n=56,185) and Meta-Analysis
Teira Calderon, A.; (...); Garcia-Garcia, H. M.
Meeting Abstract. 2024
Dynamics and prognostic role of persistent angina in chronic coronary syndrome with clinical, angiographic and stress CMR evidence of ischemia
Merenciano-Gonzalez, H.; (...); Bodi, V
Meeting Abstract. 10.1093/eurheartj/ehae666.1329. 2024
Endothelial Biomarkers Are Superior to Classic Inflammatory Biomarkers in Community-Acquired Pneumonia.
González-Jiménez P; (...); Méndez R
Article. 10.3390/biomedicines12102413. 2024
Exploring the Synergy between Nano-Formulated Linezolid and Polymyxin B as a Gram-Negative Effective Antibiotic Delivery System Based on Mesoporous Silica Nanoparticles
Otri, Ismael; (...); Sancenon, Felix
Article. 10.3390/nano14020228. 2024
Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction.
Amaro-Prellezo, Elena; (...); Sepulveda, Pilar
Article. 10.1186/s41232-024-00340-7. 2024
Hypertension as predictive factor for bevacizumab-containing first-line therapy in metastatic breast and colorectal cancer in BRECOL (GEICAM/2011-04) study.
Rodríguez-Lescure Á; (...); de la Haba-Rodriguez J
Article. 10.1007/s12094-024-03411-w. 2024
Impact on Survival of Heart and Heart-Lung Transplantation in Patients With Cyanotic and Noncyanotic Congenital Heart Diseases.
Donoso-Trenado, Victor; (...); Almenar-bonet, Luis
Article. 10.1016/j.transproceed.2024.12.005. 2024
Initial and Residual Cardiovascular Damage Remaining at Day 30 in Community-acquired Pneumonia
Ocana, R. Mendez; (...); Menendez, R.
Meeting Abstract. https://doi.org/10.1164/ajrccm-conference.2024.209.1_MeetingAbstracts.A6241. 2024
Metabolomic study for the identification of symptomatic carotid plaque biomarkers
Botello-Marabotto, Marina; (...); Miralles, Manuel
Article. 10.1016/j.talanta.2024.127211. 2025
Models of Chemical Communication for Micro/Nanoparticles.
Ventura, Jordi; (...); Martinez-Manez, Ramon
Article. 10.1021/acs.accounts.3c00619. 2024
Molecular characterization of pregnancy-associated breast cancer and insights on timing from GEICAM-EMBARCAM study.
Pena-Enriquez, Regina; (...); de la Haba-Rodriguez, Juan
Article. 10.1038/s41523-025-00718-x. 2025
Nanodevice-Mediated Immune Cell Recruitment: Targeting Senescent Cells via MMP-3-Responsive CXCL12-Coated Nanoparticles.
Escriche-Navarro, Blanca; (...); Martinez-Manez, Ramon
Article. 10.1021/acsami.4c17748. 2025
Nitroreductase-responsive gated mesoporous silica nanocarriers for hypoxia-targeted drug delivery
Barros, Mariana; (...); Gavina, Pablo
Article. 10.1016/j.ijpharm.2025.125326. 2025
Normalization approaches for extracellular vesicle-derived lipidomic fingerprints - A human milk case study
Ten-Domenech, Isabel; (...); Kuligowski, Julia
Article. 10.1016/j.chemolab.2024.105070. 2024
Novel Fibrillar and Non-Fibrillar Collagens Involved in Fibrotic Scar Formation after Myocardial Infarction
Ortega, Maria; (...); Ruiz-Sauri, Amparo
Article. 10.3390/ijms25126625. 2024
Optimization through iv maintenance with ustekinumab in Inflammatory Bowel Disease. Efficacy and adjusted regimen in real world
Minguez, A.; (...); Bastida, G.
Meeting Abstract. 2024
Oxylipin profile of human milk and human milk-derived extracellular vesicles.
Albiach-Delgado, Abel; (...); Quintas, Guillermo
Article. 10.1016/j.aca.2024.342759. 2024
Penetrance of Dilated Cardiomyopathy in Genotype-Positive Relatives.
Cabrera-Romero E; (...); Garcia-Pavia P
Article. 10.1016/j.jacc.2024.02.036. 2024
Pharmacological Considerations during Percutaneous Treatment of Heart Failure.
Sorolla-Romero JA; (...); Sanz-Sanchez j
Article. 10.2174/0113816128284131240209113009. 2024
Phase II clinical trial assessing the efficacy of enzalutamide in advanced non-resectable granulosa cell ovarian tumors: The GREKO III study (GETHI2016-01).
García-Donas J; (...); Navarro P
Article. 10.1016/j.ygyno.2024.10.019. 2024
Plaque modification and impact on the microcirculation territory after drug-coated balloon angioplasty. The PLAMI study design
Romero, Jose Antonio Sorolla; (...); Sanchez, Jorge Sanz
Article. 10.24875/RECIC.M23000438. 2024
Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation
Delgado-Arija, Marta; (...); Rosello-Lleti, Esther
Article. 10.1186/s12967-024-04900-w. 2024
Plasma mutational burden in PIK3CA and TP53 independently predicts early progression in patients with HR+/HER2-metastatic breast cancer (MBC) enrolled in the GEICAM/2014-12 FLIPPER trial
Gustavo, Federico; (...); Albanell, Joan
Meeting Abstract. https://doi.org/10.1200/JCO.2024.42.16_suppl.1029. 2024
Practical Requirements for the Development of an Advanced Cardiorenal Unit
Almenar-Bonet, Luis; (...); Sanchez-Perez, Pilar
Review. 10.1159/000536104. 2024
Prognostic role of persistent angina after percutaneous revascularization in chronic coronary syndrome with altered angiography and stress CMR.
Perez-Sole, Nerea; (...); Bodi, Vicente
Article. 10.1016/j.rec.2024.09.004. 2024
Pulmonary arterial hypertension associated with pretricuspid shunts: risk profile and survival.
Calvo-Asensio, Maria; (...); Rueda Soriano, Joaquin
Article. 10.1016/j.rec.2024.04.016. 2024
Remarkable enhancement of cinnamaldehyde antimicrobial activity encapsulated in capped mesoporous nanoparticles: A new "nanokiller" approach in the era of antimicrobial resistance.
Morellá-Aucejo Á; (...); Bernardos A
Article. 10.1016/j.bioadv.2024.213840. 2024
Renal-clearable probes for disease detection and monitoring.
Dominguez, Marcia; (...); Martinez-Manez, Ramon
Article. 10.1016/j.tibtech.2024.11.020. 2024
Role of the receptor for advanced glycation end products (RAGE) in blood as a potential biomarker for progression to olaparib: A post hoc analysis of patients with platinum-resistant ovarian cancer (PROC) treated in the ROLANDO-GEICO 1601 trial
Perez-Fidalgo, Jose Alejandro; (...); Gonzalez-Martin, Antonio
Meeting Abstract. 2024
SARS-CoV-2 N protein IgG antibody detection employing nanoporous anodized alumina: A rapid and selective alternative for identifying naturally infected individuals in populations vaccinated with spike protein (S)-based vaccines
Esteve-Sanchez, Yoel; (...); Climent, Estela
Article. 10.1016/j.snb.2024.136378. 2024
SARS-COV-2 viral RNA detection through oligonucleotide-capped nanoporous anodic alumina supports.
Lopez-Palacios, Alba; (...); Climent, Estela
Article. 10.1016/j.snr.2025.100298. 2025
Self-propelled enzyme-controlled IR-mesoporous silica Janus nanomotor for smart delivery
Mayol, Beatriz; (...); Villalonga, Reynaldo
Article. 10.1016/j.jcis.2024.05.134. 2024
Sex and clinical outcomes in new-onset heart failure.
Vicent, Lourdes; (...); Martinez-Selles, Manuel
Article. 10.1016/j.ijcard.2025.133092. 2025
Synergistic antimicrobial photodynamic therapy using gated mesoporous silica nanoparticles containing curcumin and polymyxin B.
Medaglia, Serena; (...); Martinez-Manez, Ramon
Article. 10.1016/j.ijpharm.2024.123947. 2024
Synthesis of a Pd2L4 Hydrazone Molecular Cage Through Multiple Reaction Pathways
Monta-Gonzalez, Giovanni, Martinez-Manez, Ramon, Marti-Centelles, Vicente
Article. 10.3390/ijms252211861. 2024
Systematic study of the implications of calcination and solvent extraction of the surfactant in MCM-41-type mesoporous silica nanoparticles
Candela-Noguera, Vicente; (...); Martinez-Manez, Ramon
Article. 10.1016/j.micromeso.2024.113119. 2024
Tear metabolomics for the diagnosis of primary open-angle glaucoma.
Botello-Marabotto M; (...); Martínez-Máñez R
Article. 10.1016/j.talanta.2024.125826. 2024
Use of an electrospun bioveil is safe and does not decrease skin graft take on burn wounds: A randomised, controlled clinical trial.
Perez-Del-Caz, Maria Dolores; (...); Perez-Plaza, Aranzazu
Article. 10.1016/j.burns.2025.107427. 2025
Use of liquid biomarker thymidine kinase activity (TKa) to predict outcome and progression in patients with metastatic breast cancer (MBC) in the GEICAM/2014-12 FLIPPER trial
Albanell, Joan; (...); Rojo Todo, Federico Gustavo
Meeting Abstract. https://doi.org/10.1200/JCO.2024.42.16_suppl.1028. 2024
Usefulness of biomarkers to predict prognosis after heart transplant
Lopez-Vilella, Raquel; (...); Boneta, Luis Almenar
Article. 10.1016/j.rec.2024.04.019. 2024
Water-Soluble Molecular Cages for Biological Applications
Monta-Gonzalez, Giovanni; (...); Marti-Centelles, Vicente
Review. 10.3390/molecules29071621. 2024