1. Inicio
  2. Proyectos y Estudios
  3. Estudio prospectivo, aleatorizado, multicéntrico, abierto, guiado por eventos, para evaluar la no inferioridad de una estrategia personalizada de precisión para la prevención de la muerte súbita en pacientes con miocardiopatía dilatada no isquémica. ESTUDIO CIBER-SPANISH I”.

Estudio prospectivo, aleatorizado, multicéntrico, abierto, guiado por eventos, para evaluar la no inferioridad de una estrategia personalizada de precisión para la prevención de la muerte súbita en pacientes con miocardiopatía dilatada no isquémica. ESTUDIO CIBER-SPANISH I”.

Datos básicos

Código:
SPANISH-I
Protocolo:
SPANISH-I
EUDRACT:
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Dotación:
Año de incio:
2023
Año de finalización:
ESTUDIO OBSERVACIONAL

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

CONSORCIO CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED (CIBER)

Resultados del Ensayo Clínico

Ability of antigen carbohydrate 125 for diagnosis of heart failure with preserved ejection fraction

De Juan Baguda, J. Javier; (...); Delgado Jimenez, J. F.

Meeting Abstract. 2024


Acute performance of stylet driven leads for left bundle branch area pacing: A comparison with lumenless leads

Cano, Oscar; (...); Batul, Syeda Atiqa

Article. 10.1016/j.hroo.2023.11.014. 2023


Alterations in Mitochondrial Oxidative Phosphorylation System: Relationship of Complex V and Cardiac Dysfunction in Human Heart Failure

Gimenez-Escamilla, Isaac; (...); Rosello-Lleti, Esther

Article. 10.3390/antiox13030285. 2024


Altered MicroRNA Maturation in Ischemic Hearts: Implication of Hypoxia on XPO5 and DICER1 Dysregulation and RedoximiR State.

Perez-Carrillo, Lorena; (...); Rosello-Lleti, Esther

Article. 10.3390/antiox12071337. 2023


Analysis of complications in patients with ECMO as a bridge to transplantation since the beginning of the technique (2007-2023)

Guerrero Cervera, Borja; (...); Almenar Bonet, Luis

Meeting Abstract. 2024


Annual evolution of the prescription of drugs with prognostic implications in acute decompensated heart failure with reduced ejection fraction.

López-Vilella R; (...); Almenar Bonet L

Article. 10.1186/s12872-024-03728-y. 2024


CA125: a new biomarker in patients with Fontan circulation (vol 76, pg 112, 2023)

Fuentes, Francisco Buendia; (...); Soriano, Joaquin Rueda

Correction. 10.1016/j.rec.2023.03.018. 2023


Cadaveric Adipose-Derived Stem Cells for Regenerative Medicine and Research.

Milian, Lara; (...); Zorio, Esther

Article. 10.3390/ijms242115696. 2023


Cardiomyopathy associated with primary carnitine deficiency in adults: lack of complete response in patients with delayed treatment initiation

Cervera, Borja Guerrero; (...); Zorio, Esther

Letter. 10.1016/j.recesp.2023.08.011. 2024


Cardiomyopathy associated with primary carnitine deficiency in adults: lack of complete response in patients with delayed treatment initiation.

Guerrero Cervera B; (...); Zorio E

Case Reports. 10.1016/j.rec.2023.08.011. 2024


Circulating long non-coding RNAs detection after heart transplantation and its accuracy in the diagnosis of acute cardiac rejection.

Pérez-Carrillo L; (...); Roselló-Lletí E

Letter. 10.1186/s40364-024-00590-0. 2024


Clinical phenotypes according to diuretic combination in acute heart failure.

Lopez-Vilella, Raquel; (...); Bonet, Luis Almenar

Article. 10.1016/j.hjc.2023.03.009. 2023


Clinical profiling of patients admitted with acute heart failure: a comprehensive survival analysis.

Lopez-Vilella, Raquel; (...); Almenar Bonet, Luis

Article. 10.3389/fcvm.2024.1381514. 2024


Clinical, echocardiographic and analytical patterns of biomarkers in cardiac amyloidosis; a real-world analysis.

Lopez Vilella, R. Raquel; (...); Almenar Bonet, L.

Meeting Abstract. 2024


Combining Serum miR-144-3p and miR-652-3p as Potential Biomarkers for the Early Diagnosis and Stratification of Acute Cellular Rejection in Heart Transplantation Patients.

Pérez-Carrillo L; (...); Roselló-Lletí E

Article. 10.1097/TP.0000000000004622. 2023


Comparative Temporal Analysis of Morbidity and Early Mortality in Heart Transplantation with Extracorporeal Membrane Oxygenation Support: Exploring Trends over Time

Lopez-Vilella, Raquel; (...); Bonet, Luis Almenar

Article. 10.3390/biomedicines12092109. 2024


comprehensive CMR analysis improves risk stratification in left ventricular noncompaction

Casas, G.; (...); Rodriguez-Palomares, J. F.

Meeting Abstract. 2023


Comprehensive survival analysis in acute heart failure: profiling patients through clinical examination at admission

Raquel Lopez Vilella, R.; (...); Almenar Bonet, L.

Meeting Abstract. 2024


Conduction System Pacing for Cardiac Resynchronization Therapy

Cano, Oscar; (...); Martinez-Dolz, Luis

Review. 10.3390/jcdd10110448. 2023


Culprit-Lesion Drug-Coated-Balloon Percutaneous Coronary Intervention in Patients Presenting with ST-Elevation Myocardial Infarction (STEMI)

Sanz-Sanchez, Jorge; (...); Santos, Ignacio Amat

Article. 10.3390/jcm14030869. 2025


Disparate molecular mechanisms in cardiac ryanodine receptor channelopathies

Zhang, Yadan; (...); Zissimopoulos, Spyros

Article. 10.3389/fmolb.2024.1505698. 2024


Does fractional flow reserve impact on clinical outcomes by reducing number of stents and contrast media? Findings from a systematic review (N = 56,185) and meta-analysis.

Teira Calderón A; (...); Garcia-Garcia HM

Letter. 10.1016/j.carrev.2023.12.010. 2024


Does Fractional Flow Reserve Impact on Clinical Outcomes? Findings From a Systematic Review (n=56,185) and Meta-Analysis

Teira Calderon, A.; (...); Garcia-Garcia, H. M.

Meeting Abstract. 2024

  • Open Access.

Dynamics and prognostic role of persistent angina in chronic coronary syndrome with clinical, angiographic and stress CMR evidence of ischemia

Merenciano-Gonzalez, H.; (...); Bodi, V

Meeting Abstract. 10.1093/eurheartj/ehae666.1329. 2024

  • Open Access.

Electrophysiological Phenotype-Genotype Study of Sustained Monomorphic Ventricular Tachycardia in Inherited, High Arrhythmic Risk, Left Ventricular Cardiomyopathy.

Cabrera-Borrego, Eva; (...); Jimenez-Jaimez, Juan

Article. 10.1161/CIRCEP.124.013145. 2024


Endothelial Biomarkers Are Superior to Classic Inflammatory Biomarkers in Community-Acquired Pneumonia.

González-Jiménez P; (...); Méndez R

Article. 10.3390/biomedicines12102413. 2024


Extracellular Kir2.1(C122Y) Mutant Upsets Kir2.1-PIP(2) Bonds and Is Arrhythmogenic in Andersen-Tawil Syndrome.

Cruz FM; (...); Jalife J

Article. 10.1161/CIRCRESAHA.123.323895. 2024


Flecainide Is Associated With a Lower Incidence of Arrhythmic Events in a Large Cohort of Patients With Catecholaminergic Polymorphic Ventricular Tachycardia.

Bergeman, Auke T.; (...); van der Werf, Christian

Article. 10.1161/CIRCULATIONAHA.123.064786. 2023


Hereditary transthyretin amyloidosis caused by the Val142Ile variant in Spain.

de Frutos, Fernando; (...); Gonzalez-Costello, Jose

Article. 10.1016/j.rec.2024.12.012. 2025


Hypertrophic cardiomyopathy due to truncating variants in myosin binding protein C: a Spanish cohort

Melendo-Viu, Maria; (...); Palomino Doza, Julian A.

Article. 10.1136/openhrt-2024-002891. 2024


Impact of Advanced Age on the Incidence of Major Adverse Cardiovascular Events in Patients with Type 2 Diabetes Mellitus and Stable Coronary Artery Disease in a Real-World Setting in Spain.

González-Juanatey C; (...); Savana Research Group

Article. 10.3390/jcm12165218. 2023


Impact of SARS-CoV-2 infection in patients with cardiac amyloidosis: Results of a multicentre registry.

Larrañaga-Moreira JM; (...); Barriales-Villa R

Article. 10.1016/j.medcli.2023.06.025. 2023


Impact on Survival of Heart and Heart-Lung Transplantation in Patients With Cyanotic and Noncyanotic Congenital Heart Diseases.

Donoso-Trenado, Victor; (...); Almenar-bonet, Luis

Article. 10.1016/j.transproceed.2024.12.005. 2024


Improvement in left atrial strain following ferric carboxymaltose in heart failure: an analysis of the Myocardial-IRON trial.

Santas E; (...); Núñez J

Article. 10.1002/ehf2.14630. 2023


Initial and Residual Cardiovascular Damage Remaining at Day 30 in Community-acquired Pneumonia

Ocana, R. Mendez; (...); Menendez, R.

Meeting Abstract. https://doi.org/10.1164/ajrccm-conference.2024.209.1_MeetingAbstracts.A6241. 2024

  • Open Access.

Is the Benefit of Treating Iron Deficiency Greater in Acute Heart Failure with Renal Dysfunction?

Lopez-Vilella, Raquel; (...); Almenar Bonet L

Article. 10.3390/life13040915. 2023


Is the benefit of treating iron deficiency greater in acute heart failure with renal dysfunction?

Lopez Vilella, R. Raquel; (...); Bonet, L. Almenar

Meeting Abstract. 2023


Left bundle branch pacing versus left ventricular septal pacing as a primary procedural endpoint during left bundle branch area pacing: Evaluation of two different implant strategies.

Cano, Oscar; (...); Martinez-Dolz, Luis

Article. 10.1111/jce.16128. 2023


Left ventricular ejection fraction decline and cardiovascular events in suspected cardiomyopathy with excessive trabeculation: toward precision medicine.

Casas, Guillem; (...); Rodriguez-Palomares, Jose F

Article. 10.1016/j.rec.2025.01.011. 2025


Mortality after the first hospital admission for acute heart failure de novo vs. acutely decompensated heart failure with reduced ejection fraction

Lopez Vilella, R. Raquel; (...); Almenar Bonet, L.

Meeting Abstract. 2023


Mortality After the First Hospital Admission for Acute Heart Failure, De Novo Versus Acutely Decompensated Heart Failure With Reduced Ejection Fraction.

Lopez-Vilella, Raquel; (...); Almenar Bonet, Luis

Article. 10.1016/j.amjcard.2023.03.008. 2023


New ECG biomarkers and sex-stratified models for the detection of Arrhythmogenic Cardiomyopathy with left ventricular involvement

Jimenez-Serrano, Santiago; (...); Castells, Francisco

Article. 10.1016/j.bspc.2024.107224. 2025


Novel Fibrillar and Non-Fibrillar Collagens Involved in Fibrotic Scar Formation after Myocardial Infarction

Ortega, Maria; (...); Ruiz-Sauri, Amparo

Article. 10.3390/ijms25126625. 2024


Penetrance of Dilated Cardiomyopathy in Genotype-Positive Relatives.

Cabrera-Romero E; (...); Garcia-Pavia P

Article. 10.1016/j.jacc.2024.02.036. 2024


Pharmacological Considerations during Percutaneous Treatment of Heart Failure.

Sorolla-Romero JA; (...); Sanz-Sanchez j

Article. 10.2174/0113816128284131240209113009. 2024


Phenotype and Clinical Outcomes in Desmin-Related Arrhythmogenic Cardiomyopathy.

Bermudez-Jimenez FJ; (...); Jimenez-Jaimez J

Article. 10.1016/j.jacep.2024.02.031. 2024


Plaque modification and impact on the microcirculation territory after drug-coated balloon angioplasty. The PLAMI study design

Romero, Jose Antonio Sorolla; (...); Sanchez, Jorge Sanz

Article. 10.24875/RECIC.M23000438. 2024

  • Open Access.

Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation

Delgado-Arija, Marta; (...); Rosello-Lleti, Esther

Article. 10.1186/s12967-024-04900-w. 2024


Practical Requirements for the Development of an Advanced Cardiorenal Unit

Almenar-Bonet, Luis; (...); Sanchez-Perez, Pilar

Review. 10.1159/000536104. 2024


Pregnancy in women with dilated cardiomyopathy genetic variants.

Restrepo-Córdoba MA; (...); García-Pavía P

Article. 10.1016/j.rec.2024.04.002. 2024


Prevalence, characteristics, and phenotype associated with tachycardiomyopathy in a cohort of patients first hospitalized for heart failure with reduced ejection fraction

Otero Garcia, O.; (...); Gonzalez-Juanatey, J. R.

Meeting Abstract. 2024


Prognostic determinants in patients with heart failure with reduced ejection fraction after a first hospitalisation for acute heart failure. COMFE registry

Vega, D. Garcia; (...); Gonzalez-Juanatey, J. R.

Meeting Abstract. 10.1093/eurheartj/ehae666.1187. 2024

  • Open Access.

Prognostic determinants in patients with heart failure with reduced ejection fraction after a first hospitalisation for acute heart failure. implications for their clinical management. COMFE registry

Garcia Vega, D. David; (...); Gonzalez-Juanatey, J. R.

Meeting Abstract. https://doi.org/10.1093/eurheartj/ehae666.1187. 2024

  • Open Access.

Prognostic role of persistent angina after percutaneous revascularization in chronic coronary syndrome with altered angiography and stress CMR.

Perez-Sole, Nerea; (...); Bodi, Vicente

Article. 10.1016/j.rec.2024.09.004. 2024

  • Open Access.

Pulmonary arterial hypertension associated with pretricuspid shunts: risk profile and survival.

Calvo-Asensio, Maria; (...); Rueda Soriano, Joaquin

Article. 10.1016/j.rec.2024.04.016. 2024

  • Open Access.

Sex and clinical outcomes in new-onset heart failure.

Vicent, Lourdes; (...); Martinez-Selles, Manuel

Article. 10.1016/j.ijcard.2025.133092. 2025


Sinus rhythm restoration as an independent predictor of left ventricular ejection fraction improvement in patients with the first hospitalization for heart failure and reduced ejection fraction

Otero Garcia, O. Oscar; (...); Gonzalez-Juanatey, J. R.

Meeting Abstract. https://doi.org/10.1093/eurheartj/ehae666.836. 2024

  • Open Access.

Sinus rhythm restoration as an independent predictor of left ventricular ejection fraction improvement in patients with the first hospitalization for heart failure and reduced ejection fraction

Garcia, O. Otero; (...); Gonzalez-Juanatey, J. R.

Meeting Abstract. 10.1093/eurheartj/ehae666.836. 2024

  • Open Access.

Therapeutic approach in heart failure with poor diuretic response. Peripheral ultrafiltration vs. conventional treatment

Lopez-Vilella, R.; (...); Almenar Bonet, L.

Meeting Abstract. 2023


Therapeutic approach in heart failure with poor diuretic response: peripheral ultrafiltration vs. conventional treatment.

López-Vilella R; (...); Almenar Bonet L

Article. 10.1002/ehf2.14386. 2023


Titin Missense Variants as a Cause of Familial Dilated Cardiomyopathy.

Dominguez, Fernando; (...); Garcia-Pavia, Pablo

Letter. 10.1161/CIRCULATIONAHA.122.062833. 2023


Unveiling the prognostic journey: renal function trajectories in 'de novo' heart failure with reduced ejection fraction - insights from a cohort study and their impact on patient outcomes

Garcia, O. Otero; (...); Gonzalez-Juanatey, J. R.

Meeting Abstract. 10.1093/eurheartj/ehae666.835. 2024

  • Open Access.

Usefulness of biomarkers to predict prognosis after heart transplant

Lopez-Vilella, Raquel; (...); Boneta, Luis Almenar

Article. 10.1016/j.rec.2024.04.019. 2024

  • Open Access.

Usefulness of short-term peripheral ambulatory ultrafiltration in heart failure refractory to diuretics. Initial experience.

Guerrero Cervera B; (...); Almenar Bonet L

Article. 10.1016/j.medcli.2023.04.008. 2023


What clinical parameters are associated with the prescription at hospital discharge of all medications with prognostic improvement? Analysis in de novo heart failure with reduced ejection fraction

Lopez Vilella, R. Raquel; (...); Bonet, Almenar

Meeting Abstract. 2024


What factors are associated with myocardial recovery following admission for acute heart failure? Study in patients with de novo diagnosis and reduced left ventricular ejection fraction

Donoso Trenado, V.; (...); Almenar-Bonet, L.

Meeting Abstract. 2024


Campos de estudio

Compartir