Desarrollo y validación de un sistema inteligente no invasivo de diagnóstico de rechazo cardíaco y de pronóstico postrasplante.

Datos básicos

Código:
PMPTA22/00184
Protocolo:
PMPTA22/00184
EUDRACT:
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Dotación:
279.631,00 €
Año de incio:
2023
Año de finalización:
2025
PI BIOMÉDICA NACIONAL Finan. Competitiva Pública

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

ESTHER ROSELLÓ LLETÍ
FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA
INSTITUTO DE SALUD CARLOS III

Resultados del Ensayo Clínico


Ability of antigen carbohydrate 125 for diagnosis of heart failure with preserved ejection fraction

De Juan Baguda, J. Javier; (...); Delgado Jimenez, J. F.

Meeting Abstract. 2024


Acute performance of stylet driven leads for left bundle branch area pacing: A comparison with lumenless leads

Cano, Oscar; (...); Batul, Syeda Atiqa

Article. 10.1016/j.hroo.2023.11.014. 2023


Alteration in Golgi apparatus fragmentation related genes in human dilated cardiomyopathy.

Gonzalez-Torrent, Irene; (...); Rosello-Lleti, Esther

Article. 10.1038/s41598-025-92758-3. 2025


Alterations in Mitochondrial Oxidative Phosphorylation System: Relationship of Complex V and Cardiac Dysfunction in Human Heart Failure

Gimenez-Escamilla, Isaac; (...); Rosello-Lleti, Esther

Article. 10.3390/antiox13030285. 2024


Alterations of mitochondrial bioenergetics in human hearts with ischemic and dilated cardiomyopathy

Tarazon, E.; (...); Rosello-Lleti, E.

Meeting Abstract. 2023


Altered MicroRNA Maturation in Ischemic Hearts: Implication of Hypoxia on XPO5 and DICER1 Dysregulation and RedoximiR State.

Perez-Carrillo, Lorena; (...); Rosello-Lleti, Esther

Article. 10.3390/antiox12071337. 2023


Altered miRNA maturation in ischemic cardiomyopathy: implication of miRNA biogenesis and redox-sensitive miRNA regulation

Estefania Tarazon, E. T.; (...); Rosello-Lleti, E.

Meeting Abstract. 2023


Analysis of complications in patients with ECMO as a bridge to transplantation since the beginning of the technique (2007-2023)

Guerrero Cervera, Borja; (...); Almenar Bonet, Luis

Meeting Abstract. 2024


Analysis of the snoRNA profile in ischemic and dilated cardiomyopathy

Tarazon, E.; (...); Rosello-Lleti, E.

Meeting Abstract. 2023


Annual evolution of the prescription of drugs with prognostic implications in acute decompensated heart failure with reduced ejection fraction.

López-Vilella R; (...); Almenar Bonet L

Article. 10.1186/s12872-024-03728-y. 2024


CA125: a new biomarker in patients with Fontan circulation (vol 76, pg 112, 2023)

Fuentes, Francisco Buendia; (...); Soriano, Joaquin Rueda

Correction. 10.1016/j.rec.2023.03.018. 2023


Cardiac rejection diagnosis using serum mRNA encoding proteins related to fibrotic process

Rosello-Lleti, E.; (...); Tarazon, E.

Meeting Abstract. 2023


Circulating long non-coding RNAs detection after heart transplantation and its accuracy in the diagnosis of acute cardiac rejection.

Pérez-Carrillo L; (...); Roselló-Lletí E

Letter. 10.1186/s40364-024-00590-0. 2024


Clinical phenotypes according to diuretic combination in acute heart failure.

Lopez-Vilella, Raquel; (...); Bonet, Luis Almenar

Article. 10.1016/j.hjc.2023.03.009. 2023


Clinical profiling of patients admitted with acute heart failure: a comprehensive survival analysis.

Lopez-Vilella, Raquel; (...); Almenar Bonet, Luis

Article. 10.3389/fcvm.2024.1381514. 2024


Clinical, echocardiographic and analytical patterns of biomarkers in cardiac amyloidosis; a real-world analysis.

Lopez Vilella, R. Raquel; (...); Almenar Bonet, L.

Meeting Abstract. 2024


Combining Serum miR-144-3p and miR-652-3p as Potential Biomarkers for the Early Diagnosis and Stratification of Acute Cellular Rejection in Heart Transplantation Patients.

Pérez-Carrillo L; (...); Roselló-Lletí E

Article. 10.1097/TP.0000000000004622. 2023


Comparative Temporal Analysis of Morbidity and Early Mortality in Heart Transplantation with Extracorporeal Membrane Oxygenation Support: Exploring Trends over Time

Lopez-Vilella, Raquel; (...); Bonet, Luis Almenar

Article. 10.3390/biomedicines12092109. 2024


Comprehensive survival analysis in acute heart failure: profiling patients through clinical examination at admission

Raquel Lopez Vilella, R.; (...); Almenar Bonet, L.

Meeting Abstract. 2024


Conduction System Pacing for Cardiac Resynchronization Therapy

Cano, Oscar; (...); Martinez-Dolz, Luis

Review. 10.3390/jcdd10110448. 2023


Culprit-Lesion Drug-Coated-Balloon Percutaneous Coronary Intervention in Patients Presenting with ST-Elevation Myocardial Infarction (STEMI)

Sanz-Sanchez, Jorge; (...); Santos, Ignacio Amat

Article. 10.3390/jcm14030869. 2025


Disturbance of iron metabolism related genes in advanced heart failure

Tarazon, E.; (...); Rosello-Lleti, E.

Meeting Abstract. 2023


Does fractional flow reserve impact on clinical outcomes by reducing number of stents and contrast media? Findings from a systematic review (N = 56,185) and meta-analysis.

Teira Calderón A; (...); Garcia-Garcia HM

Letter. 10.1016/j.carrev.2023.12.010. 2024


Does Fractional Flow Reserve Impact on Clinical Outcomes? Findings From a Systematic Review (n=56,185) and Meta-Analysis

Teira Calderon, A.; (...); Garcia-Garcia, H. M.

Meeting Abstract. 2024

  • Open Access.

Dynamics and prognostic role of persistent angina in chronic coronary syndrome with clinical, angiographic and stress CMR evidence of ischemia

Merenciano-Gonzalez, H.; (...); Bodi, V

Meeting Abstract. 10.1093/eurheartj/ehae666.1329. 2024

  • Open Access.

Emerging role of circulating piRNAs in the diagnosis of heart transplant rejection.

Perez-Carrillo, Lorena; (...); Rosello-Lleti, Esther

Article. 10.1016/j.healun.2024.11.039. 2024


Endothelial Biomarkers Are Superior to Classic Inflammatory Biomarkers in Community-Acquired Pneumonia.

González-Jiménez P; (...); Méndez R

Article. 10.3390/biomedicines12102413. 2024


Human recombinant relaxin-2 (serelaxin) regulates the proteome, lipidome, lipid metabolism and inflammatory profile of rat visceral adipose tissue.

Aragon-Herrera, Alana; (...); Lago, Francisca

Article. 10.1016/j.bcp.2024.116157. 2024


Impact of Advanced Age on the Incidence of Major Adverse Cardiovascular Events in Patients with Type 2 Diabetes Mellitus and Stable Coronary Artery Disease in a Real-World Setting in Spain.

González-Juanatey C; (...); Savana Research Group

Article. 10.3390/jcm12165218. 2023


Impact on Survival of Heart and Heart-Lung Transplantation in Patients With Cyanotic and Noncyanotic Congenital Heart Diseases.

Donoso-Trenado, Victor; (...); Almenar-bonet, Luis

Article. 10.1016/j.transproceed.2024.12.005. 2024


Initial and Residual Cardiovascular Damage Remaining at Day 30 in Community-acquired Pneumonia

Ocana, R. Mendez; (...); Menendez, R.

Meeting Abstract. https://doi.org/10.1164/ajrccm-conference.2024.209.1_MeetingAbstracts.A6241. 2024

  • Open Access.

Is the Benefit of Treating Iron Deficiency Greater in Acute Heart Failure with Renal Dysfunction?

Lopez-Vilella, Raquel; (...); Almenar Bonet L

Article. 10.3390/life13040915. 2023


Left bundle branch pacing versus left ventricular septal pacing as a primary procedural endpoint during left bundle branch area pacing: Evaluation of two different implant strategies.

Cano, Oscar; (...); Martinez-Dolz, Luis

Article. 10.1111/jce.16128. 2023


Meteorin-like plasma levels as a novel biomarker for heart failure

Anido Varela, L.; (...); Gonzalez-Juanatey, J. R.

Meeting Abstract. 2023


Meteorin-like plasma levels as a novel biomarker for heart failure

Feijoo-Bandin, S.; (...); Gonzalez-Juanatey, J. R.

Meeting Abstract. 2024


Meteorin-like protein plasma levels are associated with worse outcomes in de novo heart failure.

Anido-Varela, Laura; (...); Lago, Francisca

Article. 10.1111/eci.14380. 2025


Mortality after the first hospital admission for acute heart failure de novo vs. acutely decompensated heart failure with reduced ejection fraction

Lopez Vilella, R. Raquel; (...); Almenar Bonet, L.

Meeting Abstract. 2023


Mortality After the First Hospital Admission for Acute Heart Failure, De Novo Versus Acutely Decompensated Heart Failure With Reduced Ejection Fraction.

Lopez-Vilella, Raquel; (...); Almenar Bonet, Luis

Article. 10.1016/j.amjcard.2023.03.008. 2023


Novel Fibrillar and Non-Fibrillar Collagens Involved in Fibrotic Scar Formation after Myocardial Infarction

Ortega, Maria; (...); Ruiz-Sauri, Amparo

Article. 10.3390/ijms25126625. 2024


Penetrance of Dilated Cardiomyopathy in Genotype-Positive Relatives.

Cabrera-Romero E; (...); Garcia-Pavia P

Article. 10.1016/j.jacc.2024.02.036. 2024


Pharmacological Considerations during Percutaneous Treatment of Heart Failure.

Sorolla-Romero JA; (...); Sanz-Sanchez j

Article. 10.2174/0113816128284131240209113009. 2024


Plaque modification and impact on the microcirculation territory after drug-coated balloon angioplasty. The PLAMI study design

Romero, Jose Antonio Sorolla; (...); Sanchez, Jorge Sanz

Article. 10.24875/RECIC.M23000438. 2024

  • Open Access.

Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation

Delgado-Arija, Marta; (...); Rosello-Lleti, Esther

Article. 10.1186/s12967-024-04900-w. 2024


Practical Requirements for the Development of an Advanced Cardiorenal Unit

Almenar-Bonet, Luis; (...); Sanchez-Perez, Pilar

Review. 10.1159/000536104. 2024


Prognostic role of persistent angina after percutaneous revascularization in chronic coronary syndrome with altered angiography and stress CMR.

Perez-Sole, Nerea; (...); Bodi, Vicente

Article. 10.1016/j.rec.2024.09.004. 2024

  • Open Access.

Pulmonary arterial hypertension associated with pretricuspid shunts: risk profile and survival.

Calvo-Asensio, Maria; (...); Rueda Soriano, Joaquin

Article. 10.1016/j.rec.2024.04.016. 2024

  • Open Access.

Sex and clinical outcomes in new-onset heart failure.

Vicent, Lourdes; (...); Martinez-Selles, Manuel

Article. 10.1016/j.ijcard.2025.133092. 2025


The central role of FAP dysregulation and cardiac fibroblast activation in heart failure patients

Rosello-Lleti, E.; (...); Tarazon, E.

Meeting Abstract. 2023


The lipidomic and inflammatory profiles of visceral and subcutaneous adipose tissues are distinctly regulated by the SGLT2 inhibitor empagliflozin in Zucker diabetic fatty rats.

Aragon-Herrera, Alana; (...); Lago, Francisca

Article. 10.1016/j.biopha.2023.114535. 2023


Therapeutic approach in heart failure with poor diuretic response. Peripheral ultrafiltration vs. conventional treatment

Lopez-Vilella, R.; (...); Almenar Bonet, L.

Meeting Abstract. 2023


Therapeutic approach in heart failure with poor diuretic response: peripheral ultrafiltration vs. conventional treatment.

López-Vilella R; (...); Almenar Bonet L

Article. 10.1002/ehf2.14386. 2023


Transcriptomic Alterations in Spliceosome Components in Advanced Heart Failure: Status of Cardiac-Specific Alternative Splicing Factors

Gimenez-Escamilla, Isaac; (...); Rosello-Lleti, Esther

Article. 10.3390/ijms25179590. 2024


Usefulness of biomarkers to predict prognosis after heart transplant

Lopez-Vilella, Raquel; (...); Boneta, Luis Almenar

Article. 10.1016/j.rec.2024.04.019. 2024

  • Open Access.

Campos de estudio

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