CHIP-AML22: Improved diagnostics and survival for all children with Acute Myeloid Leukemia treated within the NOPHODB- SHIP consortium; a cross-European collaboration.

Datos básicos

Código:
101079988
Protocolo:
101079988
EUDRACT:
NCT:
Centro:
Dotación:
388.092,00 €
Año de incio:
2022
Año de finalización:
2025
PI BIOMÉDICA EUROPEA Finan. Competitiva Pública

Documentos

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Participantes

Grupos

Financiadores - Promotores

COMISION EUROPEA

Resultados del Ensayo Clínico


A Randomized Comparison of Liposomal Daunorubicin/Daunorubicin Combined with Low-Dose Cytarabine and Etoposide or High-Dose Cytarabine and Fludarabine in Induction Treatment of Pediatric AML Using MRD- Based Risk Stratification in the NOPHO-DBH AML 2012 Protocol

De Moerloose, Barbara; (...); Abrahamsson, Jonas

Meeting Abstract. 10.1182/blood-2023-187251. 2023


Accurate donor and recipient selection and a short time to transplant offer excellent outcomes in upfront hematopoietic stem cell transplantation from matched unrelated donors for pediatric severe aplastic anemia and refractory cytopenia of childhood. A study of the Spanish Pediatric Group for Hematopoietic Cell Transplantation and Cell Therapy (GETH-TC).

Uria-Oficialdegui, M Luz; (...); Diaz-de-Heredia, Cristina

Letter. 10.1038/s41409-024-02406-z. 2024


ANALYSIS OF TREATMENT AND OUTCOME OF RELAPSED ACUTE LYMPHOBLASTIC LEUKEMIA ACCORDING TO IMMUNOPHENOTYPE IN SPAIN

Ramos Elbal, Eduardo; (...); Fuster, Jose Luis

Meeting Abstract. 2023


Atypical B-Cell Acute Lymphoblastic Leukemia with iAMP21 in the Context of Constitutional Ring Chromosome 21: A Case Report and Review of the Genetic Insights.

Gil, Jose Vicente; (...); Llop, Marta

Article. 10.3390/ijms26010357. 2025

  • Open Access.

CLINICAL EXPERIENCE IN THE USE OF MESENCHYMAL STROMAL CELLS IN PEDIATRIC GRAFT-VERSUS-HOST DISEASE: ON BEHALF OF THE SPANISH GROUP OF STEM CELL TRANSPLANTATION (GETH)

Echecopar Parente, Carlos; (...); Perez-Martinez, Antonio

Meeting Abstract. 2024


Comprehensive detection of CRLF2 alterations in acute lymphoblastic leukemia: a rapid and accurate novel approach.

Gil, Jose Vicente; (...); Barragan, Eva

Article. 10.3389/fmolb.2024.1362081. 2024

  • Open Access.

Characterization of Pediatric Acute Myeloid Leukemia With t(7;12)(q36;p13)

Ostlund, Anders; (...); Palmqvist, Lars

Article. 10.1002/gcc.70003. 2024

  • Open Access.

Chip-AML22 Master Protocol: An Open-Label Clinical Trial in Newly Diagnosed Pediatric De Novo Acute Myeloid Leukemia (AML) Patients Including a Linked Phase II Trial with Quizartinib in FLT3-ITD/ NPM1wt Patients - a Study By the NOPHO-DB-SHIP Consortium

Kaspers, Gertjan J. L.; (...); Pronk, Cornelis Jan

Meeting Abstract. 10.1182/blood-2023-181792. 2023


ECLIM-SEHOP: how to develop a platform to conduct academic trials for childhood cancer.

Juan-Ribelles A; (...); Fernández-Teijeiro A

Article. 10.1007/s12094-024-03445-0. 2024

  • Open Access.

Haploidentical versus Cord Blood transplantation in pediatric AML. A retrospective outcome analysis on behalf of the pediatric subcommittee of GETH (Grupo Español de Trasplante Hematopoyético).

Sisinni L; (...); de Heredia CD

Article. 10.1016/j.jtct.2024.07.013. 2024

  • Open Access.

Haploidentical vs. HLA-matched donor hematopoietic stem-cell transplantation for pediatric patients with acute lymphoblastic leukemia in second remission: A collaborative retrospective study of the Spanish Group for Bone Marrow Transplantation in Children (GETMON/GETH) and the Spanish Childhood Relapsed ALL Board (ReALLNet).

Moreno, Celia; (...); Fuster, Jose Luis

Article. 10.3389/fped.2023.1140637. 2023

  • Open Access.

Hematopoietic stem cell transplantation in children with chronic granulomatous disease: the Spanish experience.

Alonso García L; (...); Diaz de Heredia Rubio C

Article. 10.3389/fimmu.2024.1307932. 2024

  • Open Access.

Management of Hyperleukocytosis in Pediatric Acute Myeloid Leukemia Using Immediate Chemotherapy without Leukapheresis, in Protocol NOPHO-DBH AML-2012

Zeller, Bernward; (...); Abrahamsson, Jonas

Meeting Abstract. 10.1182/blood-2023-184921. 2023


Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 Protocol.

Zeller B; (...); Abrahamsson J

Article. 10.3324/haematol.2024.285285. 2024

  • Open Access.

Measurable Residual Disease and Fusion Partner Independently Predict Survival and Relapse Risk in Childhood KMT2A-Rearranged Acute Myeloid Leukemia: A Study by the International Berlin-Frankfurt-Münster Study Group.

van Weelderen, Romy E; (...); Kaspers GJL

Article. 10.1200/JCO.22.02120. 2023

  • Open Access.

Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease.

Tierens, Anne; (...); Abrahamsson, Jonas

Article. 10.1200/JCO.23.01841. 2024


Optimized Cytogenetic Risk-Group Stratification of KMT2A-Rearranged Pediatric Acute Myeloid Leukemia.

van Weelderen, Romy E.; (...); Kaspers, Gertjan J. L.

Article. 10.1182/bloodadvances.2023011771. 2024

  • Open Access.

POST-TRANSPLANT RELAPSE IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA IN THE ERA OF CAR-T CELL THERAPY. A MULTICENTER ANALYSIS OF GRUPO ESPANOL DE TRASPLANTE HEMATOPOYETICO Y TERAPIA CELULAR (GETHTC) PEDIATRIC COMMITTEE

Vicent, Marta Gonzalez; (...); de Heredia, Cristina Diaz

Meeting Abstract. https://doi.org/10.1016/j.jcyt.2024.11.016. 2024

  • Open Access.

Post-transplant relapse in pediatric acute lymphoblastic leukemia in the era of CAR-T cell therapy. A multicenter analysis of Grupo Espanol de Trasplante Hematopoyetico y Terapia Celular (GETH-TC) Pediatric Committee.

Gonzalez Vicent, M; (...); Diaz de Heredia, C

Article. 10.1016/j.jcyt.2024.11.016. 2024


Treosulfan-Based Conditioning Regimen In Pediatric Hematopoietic Stem Cell Transplantation: A Retrospective Analysis on Behalf of the Spanish Group for Hematopoietic Transplantation and Cellular Therapy (GETH-TC).

Galán V; (...); Pérez-Martínez A

Article. 10.1016/j.jtct.2023.08.016. 2023

  • Open Access.

UNRELATED DONOR TRANSPLANTATION OFFERS A REAL CURATIVE OPPORTUNITY FOR PATIENTS WITH TRANSFUSIONDEPENDENT THALASSAEMIA. EXPERIENCE OF THE SPANISH GROUP FOR BONE MARROW TRANSPLANTATION IN CHILDREN (GETH-TC)

Benitez Carabante, Maria Isabel; (...); de Heredia Rubio, Cristina Diaz

Meeting Abstract. 2024


UPFRONT MATCHED UNRELATED DONOR HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR SEVERE IDIOPATHIC APLASTIC ANEMIA AND REFRACTORY CYTOPENIA OF CHILDHOOD IN PEDIATRIC PATIENTS. SPANISH EXPERIENCE

Uria-Oficialdegui, M. Luz; (...); Diaz-de-Heredia, Crsitina

Meeting Abstract. 2024


Use of Eculizumab in Pediatric Patients with High-Risk Transplantation-Associated Thrombotic Microangiopathy: Outcomes and Risk Factors Associated with Response and Survival. A Retrospective Study on Behalf of the Spanish Group for Hematopoietic Transplantation and Cellular Therapy (GETH-TC).

Benítez Carabante MI; (...); Diaz-de-Heredia C

Article. 10.1016/j.jtct.2024.03.019. 2024

  • Open Access.

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