Portal de investigación
Análisis del biomarcador epigenético en el semen involucrado en el riesgo de autismo en la descendencia.
Datos básicos
- Código:
- 2103-FIVI-022-NG
- Protocolo:
- 2103-FIVI-022-NG
- EUDRACT:
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Dotación:
- Año de incio:
- 2021
- Año de finalización:
- 2022
Documentos
- No hay documentos
Participantes
Grupos
Financiadores - Promotores
Resultados del Ensayo Clínico
A microRNA signature for valproate-induced steatosis in human hepatocytes and its application to predict fatty liver in paediatric epileptic patients on valproate therapy.
Soluyanova P; (...); Jover R
Article. 10.1016/j.tox.2024.153974. 2024
A sperm chromatin damage > 15% negatively impacts on the quality of embryos obtained from ovum donation ICSI cycles of unselected couples
Castro, AP; (...); Garrido, N.
Meeting Abstract. 2021
Advanced Paternal Age Does Not Affect Medically-Relevant Obstetrical and Perinatal Outcomes following IVF or ICSI in Humans with Donated Oocytes.
Navarro-Gomezlechon, Ana; (...); Garrido, Nicolas
Article. 10.3390/jcm12031014. 2023
Assessment of reproductive outcomes of fresh versus cryopreserved ejaculated sperm samples-a retrospective analysis of 44 423 oocyte donation ICSI cycles.
Gil Juliá M; (...); Garrido N
Article. 10.1093/humrep/deae088. 2024
Case Report: Novel Homozygous Likely Pathogenic SCN1A Variant With Autosomal Recessive Inheritance and Review of the Literature.
Marco Hernández AV; (...); Martinez F
Case Reports. 10.3389/fneur.2021.784892. 2021
Common genetic variation in KATNAL1 non-coding regions is involved in the susceptibility to severe phenotypes of male infertility.
Cervan-Martin, Miriam; (...); Carmona, F David
Article. 10.1111/andr.13221. 2022
Cumulative live birth rates (CLBR) per embryo transfer, embryo transferred and inseminated oocyte are not affected by paternal age in infertile male donor egg cycles
Mossetti, L.; (...); Garrido, N.
Meeting Abstract. 2021
Cumulative live birth rates in donor oocyte ICSI cycles are not improved by magnetic-activated cell sorting sperm selection.
Gil Juliá M; (...); Garrido N
Article. 10.1016/j.rbmo.2021.09.024. 2022
Dose reduction is a feasible strategy in patients with plaque psoriasis who achieve sustained response with secukinumab: a retrospective, multicenter cohort study in daily practice setting
Daudén E; (...); Llamas-Velasco M
Article. 10.1111/ijd.16915. 2024
Effect of time since vasectomy on live birth rate of TESE?ICSI egg donation cycles and male-related prognostic factors.
Hervas, Irene; (...); Garrido, Nicolas
Article. 10.1111/andr.13697. 2024
Elevated Sperm DNA Damage in IVF-ICSI Treatments Is Not Related to Pregnancy Complications and Adverse Neonatal Outcomes.
Hervas, Irene; (...); Garrido, Nicolas
Article. 10.3390/jcm12216802. 2023
Erratum to 'Cumulative live birth rates in ICSI cycles with donated oocytes are not improved by magnetic-activated cell sorting: A retrospective study in unselected males' [Reproductive BioMedicine Journal 44/4 (2022) 677-684].
Gil Juliá M; (...); Garrido N
Correction. 10.1016/j.rbmo.2023.103609. 2023
Extending the Phenotype Related to SCN1A Gene: Arthrogryposis, Movement Disorders, and Malformations of Cortical Development.
Marco-Hernandez, Ana Victoria; (...); Martinez, Francisco
Article. 10.1177/08830738211072694. 2022
Genetic Heterogeneity Underlying Phenotypes with Early-Onset Cerebellar Atrophy
Martinez-Rubio, Dolores; (...); Espinos, Carmen
Article. 10.3390/ijms242216400. 2023
Genetics of Paroxysmal Dyskinesia: Novel Variants Corroborate the Role of KCNA1 in Paroxysmal Dyskinesia and Highlight the Diverse Phenotypic Spectrum of KCNA1- and SLC2A1-Related Disorders
Kegele J; (...); Lauxmann S
Article. 10.3389/fneur.2021.701351. 2021
Higher serum progesterone level has no negative impact on live birth rate in frozen embryo transfer.
Cozzolino M; (...); Galliano D
Article. 10.1016/j.ejogrb.2024.10.011. 2024
Higher sperm DNA fragmentation reduces the proportion of good quality embryos at day 5 on IVF and ICSI cycles from unselected males
Herrero, IH; (...); Garrido, N.
Meeting Abstract. 2021
HYPERSPECTRAL IMAGING OF SINGLE SPERMATOZOA AS A PROMISING NON-DESTRUCTIVE OBJECTIVE TOOL FOR SPERM SELECTION PRIOR TO ICSI - DETERMINATION OF REPRODUCIBILITY, SENSITIVITY AND SPECIFICITY
Gil Julia, Maria; (...); Garrido Puchalt, Nicolas
Meeting Abstract. 2022
IMAGE BIOMARKERS FOR 11IE DETECTION AND MAPPING OF SPERMATOGENIC FOCI WITHIN TESTICLES BY MAGNETIC RESONANCE (MR) IMAGING, A NOVEL NON-INVASIVE TIIOL FOR AZOI/SPERMIC MALES
Herrero, Irene Hervas; (...); Puchalt, Nicolas Garrido
Meeting Abstract. 2022
IVF/ICSI cumulative live birth rates per consumed oocyte remain comparable regardless of sperm DNA fragmentation by TUNEL.
Hervas, Irene; (...); Garrido, Nicolas
Article. 10.1016/j.rbmo.2022.02.010. 2022
Lack of meaningful impact of male body mass index (BMI) on reproductive outcomes measured by cumulative live birth rates (CLBR) in 80830 IVF-ICSI treatments
Mossetti, L.; (...); Garrido Puchalt, N.
Meeting Abstract. 2023
MICROFLUIDIC-BASED SPERM SELECTION: EFFECT ON SPERM DNA FRAGMENTATION AND EMBRYO DEVELOPMENT.
Luisa Pardinas, Maria; (...); De Los Santos, Maria J.
Meeting Abstract. 2023
Mitochondrial developmental encephalopathy with bilateral optic neuropathy related to homozygous variants in IMMT gene.
Marco-Hernández AV; (...); Martínez-Castellano F
Article. 10.1111/cge.14093. 2022
New variants expand the neurological phenotype of COQ7 deficiency.
Fabra, Maria Alcazar; (...); Santos-Ocana, Carlos
Article. 10.1002/jimd.12776. 2024
NON-APOPTOTIC SPERM SELECTION BY MAGNETIC-ACTIVATED CELL SORTING (MACS) PROVEN SAFE FROM OBSTETRIC AND PERINATAL HEALTH STANDPOINT IN ICSI CYCLES WITH DONATED OOCYTES.
Gil Julia, Maria; (...); Garrido, Nicolas
Meeting Abstract. 2021
N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants
Mayo, Sonia; (...); Martinez, Francisco
Review. 10.3390/ijms24076100. 2023
Obstetrical and Perinatal Outcomes Are Not Associated with Advanced Paternal Age in IVF or ICSI Pregnancies with Autologous Oocytes.
Navarro-Gomezlechon, Ana; (...); Garrido, Nicolas
Article. 10.3390/biology12091256. 2023
Paternal age clinical effect on cumulative live birth rates (CLBR) per inseminated oocyte, embryo transfer and embryo transferred in autologous IVF-ICSI cycles of infertile males
Gomez-Lechon, AN; (...); Garrido, N.
Meeting Abstract. 2021
PATERNAL AGE HAS A SIGNIFICANT EFFECT ON CUMULATIVE LIVE BIRTH RATES ((LBR) PER INSEMINATED OOCYTE, EMBRYO TRANSFER (ET) AND EMBRYO TRANSFERRED IN IVINICSI WITH DONATED OOCYTES
Navarro Gomez-Lechon, Ana; (...); Garrido Puchalt, Nicolas
Meeting Abstract. 2022
Reading and Writing Skills in Adolescents With Autism Spectrum Disorder Without Intellectual Disability
Baixauli, I; (...); Miranda, A
Article. 10.3389/fpsyg.2021.646849. 2021
Requirements for Accessing New Dermatology Drugs in Spain: Results of the EQUIDAD Study.
Sanchez-Diaz, M.; (...); Carrascosa-Carrillo, J. M.
Article. 10.1016/j.ad.2023.10.016. 2023
Semen cryopreservation for an oncological reason: a retrospective study.
Santana-Plata, Ana, Rivera-Egea, Rocio, Garrido, Nicolas
Article. 10.1016/j.rbmo.2024.103898. 2024
Semen processing using magnetic-activated cell sorting before ICSI is deemed safe for obstetric and perinatal outcomes: a retrospective multicentre study.
Gil Julia, Maria; (...); Garrido, Nicolas
Article. 10.1016/j.rbmo.2023.01.022. 2023
Semen processing using magnetic-activated cell sorting before ICSI is deemed safe for obstetric and perinatal outcomes: a retrospective multicentre study
Julia, Maria Gil; (...); Garrido, Nicolas
Article. 10.1016/j.rbmo.2023.01.0221472. 2023
SIGNIFICANT IMPROVEMENT IN THE QUALITY OF EMBRYOS OBTAINED AFTER THE USE OF TESTICULAR SPERM FOR ICSI IN COUPLES WITH A PREVIOUS ICSI FAILURE WITH EJACULATED SPERM.
Hervas, Irene; (...); Garrido, Nicolas
Meeting Abstract. 2021
Slight decreases in cumulative live birth rates when using frozen-thawed semen samples for ICSI with donor oocytes do not mean we should stop freezing
Julia, M. Gil; (...); Garrido, N.
Meeting Abstract. 2023
Sperm deoxyribonucleic acid fragmentation (by terminal deoxynucleotidyl transferase biotin dUTP nick end labeling assay) does not impair reproductive success measured as cumulative live birth rates per donor metaphase II oocyte used.
Hervas, Irene; (...); Garrido, Nicolas
Article. 10.1016/j.fertnstert.2022.04.002. 2022
Sperm DNA fragmentation (SDF) is not associated with adverse maternal and neonatal outcomes in IVF-ICSI cycles with autologous oocytes
Egea, RR; (...); Garrido, N.
Meeting Abstract. 2021
SPERM PROCESSING BY MACS DOES NOT IMPROVE REPRODUCTIVE OUTCOMES IN CYCLES USING VITRIFIED DONOR 00CYTES WHEN COMPARED 10 STANDARD SEMEN
Gil Julia, Maria; (...); Garrido Puchalt, Nicolas
Meeting Abstract. 2022
Sperm Selection by Magnetic-Activated Cell Sorting before Microinjection of Autologous Oocytes Increases Cumulative Live Birth Rates with Limited Clinical Impact: A Retrospective Study in Unselected Males
Julia, MG; (...); Garrido, N
Article. 10.3390/biology10050430. 2021
Superior Live Birth Rates, Reducing Sperm DNA Fragmentation (SDF), and Lowering Miscarriage Rates by Using Testicular Sperm Versus Ejaculates in Intracytoplasmic Sperm Injection (ICSI) Cycles from Couples with High SDF: A Systematic Review and Meta-Analysis
Cano-Extremera, Marina; (...); Puchalt, Nicolas Garrido
Review. 10.3390/biology14020130. 2025
Switching to testicular sperm after a previous ICSI failure with ejaculated sperm significantly improves blastocyst quality without increasing aneuploidy risk
Hervas, Irene; (...); Garrido, Nicolas
Article. 10.1007/s10815-022-02595-w. 2022
TESE-ICSI outcomes per couple in vasectomized males are negatively affected by time since the intervention, but not other comorbidities.
Hervás I; (...); Martínez-Jabaloyas JM
Article. 10.1016/j.rbmo.2021.05.013. 2021
The effect of male factors on embryo morphokinetics: a retrospective analysis of 2726 blastocysts.
Pellegrini, Livia; (...); Cozzolino, Mauro
Article. 10.1007/s10815-024-03275-7. 2024
The LINCE Project: A Pathway for Diagnosing NCL2 Disease.
Rodrigues, Daniel; (...); Colon, Cristobal
Article. 10.3389/fped.2022.876688. 2022
The Use of Non-Apoptotic Sperm Selected by Magnetic Activated Cell Sorting (MACS) to Enhance Reproductive Outcomes: What the Evidence Says
Garrido, Nicolas, Gil Julia, Maria
Review. 10.3390/biology13010030. 2024
THE USE OF TESTICULAR SPERM IN COUPLES WITH A PREVIOUS ICSI FAILURE WITH EJACULATED SPERM DOES NOT DECREASE ANEUPLOIDY RATE; A RETROSPECTIVE ANALYSIS.
Hervas, Irene; (...); Garrido, Nicolas
Meeting Abstract. 2021
Venous sinus thrombosis in pediatrics. Case series of a tertiary hospital.
Rubio Atienza Y; (...); Tomás Vila M
Article. 10.32641/andespediatr.v92i3.3344. 2021