ESTUDIO OBSERVACIONAL PARA IDENTIFICAR PACIENTES CON CPNM AVANZADO/METASTÁSICO Y TRANSLOCACIÓN DE ALK Y ROS1 Y CONOCER SU MANEJO TERAPÉUTICO (IDEALKROS).

Dades bàsiques

Protocol:
PFI-ALK-2015-01 (IDEALKROS)
EURDRACT:
NCT:
Centre:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Any inici:
2021
Any de finalització:
2022
ESTUDIO OBSERVACIONAL

Documents

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Participants

Grups d'Investigació

Finançadors - Promotors

PFIZER S.L.U

Resultats de l'Assaig Clínic


A phase Ib study of CC-90011, a potent, reversible, oral LSD1 inhibitor, plus etoposide and cisplatin (EP) or carboplatin (EC) in patients (Pts) with first-line (1L) extensive-stage (ES) small cell lung cancer (SCLC): Updated results

Ponce Aix, S.; (...); Paz-Ares, L.

Meeting Abstract. 2021


A Randomized, Open-Label Phase II Study Evaluating Emibetuzumab Plus Erlotinib and Emibetuzumab Monotherapy in MET Immunohistochemistry Positive NSCLC Patients with Acquired Resistance to Erlotinib.

Camidge DR; (...); Smit E

Article. 10.1016/j.cllc.2022.03.003. 2022

  • Open Access.

Are there differences by sex in lung cancer characteristics at diagnosis? -a nationwide study.

Ruano-Ravina A; (...); Oramas J

Article. 10.21037/tlcr-21-559. 2021

  • Open Access.

Baseline circulating myeloid-derived suppressor cells correlate with neutrophil-to-lymphocyte ratio and overall survival in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors

Garcia-Sanchez, J.; (...); Lahoz, A.

Meeting Abstract. 2021


Clinical characteristics and survival in stage I-IIIA lung cancer resected patients in Spain, analyzed in the Thoracic Tumors Registry (TTR)

Franco, FF; (...); Provencio, M

Meeting Abstract. 10.1016/j.annonc.2021.08.1771. 2021

  • Open Access.

Correction: Pardo-Sánchez et al. Increased Tumor Growth Rate and Mesenchymal Properties of NSCLC-Patient-Derived Xenograft Models during Serial Transplantation. Cancers 2021, 13 , 2980.

Pardo-Sanchez, Jose Miguel; (...); Farràs R

Article. 10.3390/cancers13194825. 2021

  • Open Access.

Corrigendum to 'First-line nivolumab plus ipilimumab with 2 cycles of chemotherapy versus chemotherapy alone (4 cycles) in advanced non-small cell lung cancer: CheckMate 9LA 2-year update': [ESMO Open Volume 6, Issue 5, October 2021, 100273].

Reck, M.; (...); John, T.

Correction. 10.1016/j.esmoop.2021.100345. 2021

  • Open Access.

Determination of essential biomarkers in lung cancer: A real-world data study in Spain

Calvo de Juan, V.; (...); Provencio Pulla, M.

Meeting Abstract. 10.1016/j.annonc.2022.02.048. 2022

  • Open Access.

ECONOMIC IMPACT OF THE NSCLC MOLECULAR DIAGNOSIS IN SPAIN: A RETROSPECTIVE ANALYSIS OF HEALTHCARE RESOURCES USE AND ASSOCIATED COSTS FROM THE LUNG-ONE STUDY

de Castro, J; (...); Rojo, F

Meeting Abstract. 2020


Epidemiology, treatment, and survival in small cell lung cancer in Spain: Data from the Thoracic Tumor Registry

Franco, F; (...); Provencio, M

Article. 10.1371/journal.pone.0251761. 2021

  • Open Access.

Family History of Cancer and Lung Cancer: Information from the Thoracic Tumors Registry (TTR Study)

Calvo, V.; (...); Provencio, M.

Meeting Abstract. 2021


First-line avelumab in combination with cetuximab and chemotherapy in patients with advanced squamous non-small cell lung cancer (NSCLC)

Andric, Z. G.; (...); Ciardiello, F.

Meeting Abstract. 2021


First-line nivolumab (NIVO) plus ipilimumab (IPI) plus two cycles of chemotherapy (chemo) versus chemo alone (4 cycles) in patients with advanced non-small cell lung cancer (NSCLC): Two-year update from CheckMate 9LA.

Reck, Martin; (...); John, Tom

Meeting Abstract. 10.1200/JCO.2021.39.15_suppl.9000. 2021


First-line nivolumab (NIVO) plus ipilimumab (IPI)+2 cycles chemotherapy (chemo) vs 4 cycles chemo in advanced non-small cell lung cancer (aNSCLC): Association of blood and tissue tumor mutational burden (TMB) with efficacy in CheckMate 9LA

Paz-Ares, L.; (...); Carbone, D. P.

Meeting Abstract. 2021


First-line nivolumab (NIVO) plus ipilimumab (IPI)+2 cycles of chemotherapy (chemo) versus chemo alone (4 cycles) in patients with advanced non-small cell lung cancer (NSCLC): 2-year update from CheckMate 9LA

Reinmuth, N.; (...); John, T.

Meeting Abstract. 2021


First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial.

Paz-Ares, Luis; (...); Reck, Martin

Article. 10.1016/S1470-2045(20)30641-0. 2021


First-line Nivolumab plus Ipilimumab plus Chemo in Patients With Advanced NSCLC and Brain Metastases: Results From CheckMate 9LA

Carbone, D.; (...); Lu, S.

Meeting Abstract. 2021


First-line nivolumab plus ipilimumab with two cycles of chemotherapy versus chemotherapy alone (four cycles) in advanced non-small-cell lung cancer: CheckMate 9LA 2-year update.

Reck M; (...); John T

Article. 10.1016/j.esmoop.2021.100273. 2021

  • Open Access.

Increased Tumor Growth Rate and Mesenchymal Properties of NSCLC-Patient-Derived Xenograft Models during Serial Transplantation

Pardo-Sanchez, JM; (...); Farras, R

Article. 10.3390/cancers13122980. 2021

  • Open Access.

Liposomal Irinotecan in Adults with Small Cell Lung Cancer who Progressed on Platinum-Based Therapy: Subgroup Analyses by Platinum Sensitivity

Spigel, DR; (...); Bunn, P

Meeting Abstract. 2021


Lung Cancer Symptoms at Diagnosis: Data from the Thoracic Tumors Registry (TTR Study).

Calvo, V; (...); Provencio, M

Meeting Abstract. 2021


LungBEAM: A prospective multicenter study to monitor stage IV NSCLC patients with EGFR mutations using BEAMing technology

Garrido, P; (...); Felip, E

Article. 10.1002/cam4.4135. 2021

  • Open Access.

nab -Paclitaxel Plus Durvalumab in Patients With Previously Treated Advanced Stage Non-small Cell Lung Cancer (ABOUND.2L+).

Morgensztern D; (...); Ong TJ

Article. 10.3389/fonc.2020.569715. 2021

  • Open Access.

Nivolumab (NIVO) plus ipilimumab (IPI)+2 Cycles of Platinum-Doublet Chemotherapy (Chemo) vs. 4 Cycles Chemo as First-Line (1L) Treatment) for Stage IV/Recurrent Non-Small Cell Lung Cancer (NSCLC): CheckMate 9LA

Reck, M; (...); Paz-Ares, LG

Meeting Abstract. 2021


Osimertinib in advanced EGFR-T790M mutation-positive non-small cell lung cancer patients treated within the Special Use Medication Program in Spain: OSIREX-Spanish Lung Cancer Group.

Provencio M; (...); Calvo V

Article. 10.1186/s12885-021-07922-5. 2021

  • Open Access.

OsimertinibTreatment in Non-Small Cell Lung Cancer (NSCLC) EGFR-T790M+. Activity in Patients with CNS Metastases. OSIREX

Terrasa, J; (...); Provencio, M

Meeting Abstract. 2021


PECATI: A Multicentric, Open-Label, Single-Arm Phase II Study to Evaluate the Efficacy and Safety of Pembrolizumab and Lenvatinib in Pretreated B3-Thymoma and Thymic Carcinoma Patients.

Remon J; (...); Besse B

Article. 10.1016/j.cllc.2021.07.008. 2021

  • Open Access.

Pembrolizumab re-challenge in patients with relapsed non-small cell lung cancer (NSCLC): A preliminary report of the REPLAY phase II trial - cohort I

Ponce Aix, S.; (...); Paz-Ares, L.

Meeting Abstract. 10.1016/j.annonc.2021.10.179. 2021

  • Open Access.

Preliminary results from PROPEL: A phase I/II study of bempegaldesleukin (BEMPEG: NKTR-214) plus pembrolizumab (PEMBRO) with or without chemotherapy in patients with metastatic NSCLC

Felip, E.; (...); Ganti, A.

Meeting Abstract. 10.1016/j.annonc.2021.10.159. 2021

  • Open Access.

Profile of Comorbidities and Cancer History in Patients with mNSCLC in the Spanish Population (Thoracic Tumors Registry).

Franco, F; (...); Provencio, M

Meeting Abstract. 2021


Prognostic model of long-term advanced stage (IIIB-IV) EGFR mutated non-small cell lung cancer (NSCLC) survivors using real-life data

Gutierrez, L; (...); Provencio, M

Article. 10.1186/s12885-021-08713-8. 2021

  • Open Access.

PROPEL: A Phase 1/2 Trial of Bempegaldesleukin (NKTR-214) Plus Pembrolizumab in Lung Cancer and other Advanced Solid Tumors

Spigel, DR; (...); Reck, M

Meeting Abstract. 2021


Prospective Exploratory Analysis of Angiogenic Biomarkers in Peripheral Blood in Advanced NSCLC Patients Treated With Bevacizumab Plus Chemotherapy: The ANGIOMET Study

Jantus-Lewintre, E; (...); Grp Espanol Canc Pulmon GECP

Article. 10.3389/fonc.2021.695038. 2021

  • Open Access.

Randomized phase 3 study of the anti-disialoganglioside antibody dinutuximab and irinotecan vs irinotecan or topotecan for second-line treatment of small cell lung cancer.

Edelman, Martin J.; (...); DISTINCT Study Investigators

Article. 10.1016/j.lungcan.2022.03.003. 2022


RESILIENT part 1: A phase 2 dose-exploration and dose-expansion study of second-line liposomal irinotecan in adults with small cell lung cancer.

Paz-Ares, Luis; (...); Bunn, Paul A.

Article. 10.1002/cncr.34123. 2022

  • Open Access.

RESILIENT Part 1: Safety and Efficacy of Second-Line Liposomal Irinotecan in Patients with Small Cell Lung Cancer

Paz-Ares, L; (...); Bunn, P

Meeting Abstract. 2021


RESILIENT Part 2: A phase 3 Study of Liposomal Irinotecan in Patients with Small-Cell Lung Cancer in the Second-Line Setting

Paz-Ares, L; (...); Bunn, P

Meeting Abstract. 2021


RET Fusion Testing in Advanced Non-Small Cell Lung Carcinoma Patients: the RETING Study

Conde, E.; (...); Lopez-Rios, F.

Meeting Abstract. 2021


Second-Line Nivolumab in Relapsed Small-Cell Lung Cancer: CheckMate 331.

Spigel DR; (...); Reck M

Article. 10.1016/j.annonc.2021.01.071. 2021

  • Open Access.

Second-line treatment in advanced non-squamous (NS) non-small cell lung cancer (NSCLC) patients in Spain, analyzed in the Thoracic Tumor Registry (RTT)

Carcereny Costa, E.; (...); Provencio Pulla, M.

Meeting Abstract. 10.1016/j.annonc.2022.02.062. 2022

  • Open Access.

Seroprevalence and immunological memory against SARS-CoV-2 in lung cancer patients (p): SOLID study.

Provencio, Mariano; (...); Cobo, Manuel

Meeting Abstract. 10.1200/JCO.2021.39.15_suppl.8531. 2021


Seroprevalence and immunological memory against SARS-CoV-2 in lung cancer patients: the SOLID study.

Provencio, Mariano; (...); Cobo, Manuel

Article. 10.21037/tlcr-21-504. 2022

  • Open Access.

Stereotactic body radiation therapy: A good dance partner of oligometastatic non-small cell lung cancer to the sound of SINDAS study.

Mielgo-Rubio X; (...); Couñago F

Editorial Material. 10.5306/wjco.v11.i12.983. 2020

  • Open Access.

Thoracic Tumors Registry (RTT): Analysis of Clinical Features and Survival in Patients with mNSCLC in Spain.

Franco, F; (...); Provencio, M

Meeting Abstract. 2021


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