INFUSION DE CELULAS NATURAL KILLER ALOREACTIVAS O ESTIMULADAAS CON IL-15 EX VIVO TRAS TRASPLANTE HAPLOIDENTICO DE PROGENITORES HEMATOPOYETICOS EN PACIENTES PEDIATRICOS CON NEOPLASIAS HEMATOLOGICAS (PHINK).

Datos básicos

Protocolo:
PHINK-01/2019
EUDRACT:
2019-000911-10
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Año de incio:
2021
Año de finalización:
2023
ENSAYO CLÍNICO

Documentos

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Participantes

Grupos

Financiadores - Promotores

FUNDACIÓN DE INVESTIGACIÓN BIOMÉDICA DEL HOSPITAL UNIVERSITARIO LA PAZ

Resultados del Ensayo Clínico


A Randomized Comparison of Liposomal Daunorubicin/Daunorubicin Combined with Low-Dose Cytarabine and Etoposide or High-Dose Cytarabine and Fludarabine in Induction Treatment of Pediatric AML Using MRD- Based Risk Stratification in the NOPHO-DBH AML 2012 Protocol

De Moerloose, Barbara; (...); Abrahamsson, Jonas

Meeting Abstract. 10.1182/blood-2023-187251. 2023


ANALYSIS OF TREATMENT AND OUTCOME OF RELAPSED ACUTE LYMPHOBLASTIC LEUKEMIA ACCORDING TO IMMUNOPHENOTYPE IN SPAIN

Ramos Elbal, Eduardo; (...); Fuster, Jose Luis

Meeting Abstract. 2023


Blinatumomab to improve the outcome of children with relapsed B-cell acute lymphoblastic leukemia.

Fuster JL; (...); Dapena JL

Letter. 10.1007/s12094-021-02590-0. 2021


Casuística de tumor miofibroblástico inflamatorio en centro terciario.

Martínez Navarro G; (...); Fernández Navarro JM

Case Reports. 10.1016/j.anpedi.2020.12.007. 2021

  • Open Access.

Casuistics of inflammatory myofibroblastic tumor in a tertiary center.

Martínez Navarro G; (...); Fernández Navarro JM

Case Reports. 10.1016/j.anpede.2020.12.016. 2021

  • Open Access.

Comprehensive detection of CRLF2 alterations in acute lymphoblastic leukemia: a rapid and accurate novel approach.

Gil, Jose Vicente; (...); Barragan, Eva

Article. 10.3389/fmolb.2024.1362081. 2024

  • Open Access.

Chip-AML22 Master Protocol: An Open-Label Clinical Trial in Newly Diagnosed Pediatric De Novo Acute Myeloid Leukemia (AML) Patients Including a Linked Phase II Trial with Quizartinib in FLT3-ITD/ NPM1wt Patients - a Study By the NOPHO-DB-SHIP Consortium

Kaspers, Gertjan J. L.; (...); Pronk, Cornelis Jan

Meeting Abstract. 10.1182/blood-2023-181792. 2023


Defibrotide in Hematopoietic Stem Cell Transplant: An Study of Grupo Espanol De Trasplante Hematopoyetico (GETH) And Grupo Espanol De Trasplante De Medula En NinOS (GETMON)

Vicent, MG; (...); Diaz, MA

Meeting Abstract. 2020


Defibrotide In Hematopoietic Stem Cell Transplantation: A Multicenter Survey Study Of The Spanish Hematopoietic Stem Cell Transplantation Group (Geth).

González Vicent M; (...); Díaz MÁ

Article. 10.1111/ejh.13618. 2021


ECLIM-SEHOP: how to develop a platform to conduct academic trials for childhood cancer.

Juan-Ribelles A; (...); Fernández-Teijeiro A

Article. 10.1007/s12094-024-03445-0. 2024

  • Open Access.

Experience of the Spanish Group for Hematopoietic Transplantation (GETMON-GETH) in allogenic Hematopoietic stem cell Transplantation in Philadelphia acute lymphoblastic leukemia.

Galán Gómez V; (...); Pérez-Martínez A

Article. 10.1016/j.anpede.2021.02.016. 2022

  • Open Access.

Experiencia del Grupo Español de Trasplante Hematopoyético (GETMON-GETH) en el trasplante alogénico de progenitores hematopoyéticos en leucemia aguda linfoblástica Philadelphia.

Galán Gómez V; (...); Pérez-Martínez A

Article. 10.1016/j.anpedi.2021.02.015. 2021

  • Open Access.

Germline Predisposition to Pediatric Cancer, from Next Generation Sequencing to Medical Care.

Gargallo P; (...); Cañete A

Article. 10.3390/cancers13215339. 2021

  • Open Access.

Haploidentical vs. HLA-matched donor hematopoietic stem-cell transplantation for pediatric patients with acute lymphoblastic leukemia in second remission: A collaborative retrospective study of the Spanish Group for Bone Marrow Transplantation in Children (GETMON/GETH) and the Spanish Childhood Relapsed ALL Board (ReALLNet).

Moreno, Celia; (...); Fuster, Jose Luis

Article. 10.3389/fped.2023.1140637. 2023

  • Open Access.

Helpful Criteria When Implementing NGS Panels in Childhood Lymphoblastic Leukemia.

Vega-Garcia N; (...); Camós M

Article. 10.3390/jpm10040244. 2020

  • Open Access.

Hematopoietic stem cell transplantation in children with chronic granulomatous disease: the Spanish experience.

Alonso García L; (...); Diaz de Heredia Rubio C

Article. 10.3389/fimmu.2024.1307932. 2024

  • Open Access.

Management of Hyperleukocytosis in Pediatric Acute Myeloid Leukemia Using Immediate Chemotherapy without Leukapheresis, in Protocol NOPHO-DBH AML-2012

Zeller, Bernward; (...); Abrahamsson, Jonas

Meeting Abstract. 10.1182/blood-2023-184921. 2023


Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 Protocol.

Zeller B; (...); Abrahamsson J

Article. 10.3324/haematol.2024.285285. 2024

  • Open Access.

Measurable Residual Disease and Fusion Partner Independently Predict Survival and Relapse Risk in Childhood KMT2A-Rearranged Acute Myeloid Leukemia: A Study by the International Berlin-Frankfurt-Münster Study Group.

van Weelderen, Romy E; (...); Kaspers GJL

Article. 10.1200/JCO.22.02120. 2023

  • Open Access.

Measurable Residual Disease Assessed by Flow-Cytometry Is a Stable Prognostic Factor for Pediatric T-Cell Acute Lymphoblastic Leukemia in Consecutive SEHOP Protocols Whereas the Impact of Oncogenetics Depends on Treatment.

Vega-García N; (...); Camós M

Article. 10.3389/fped.2020.614521. 2021

  • Open Access.

Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease.

Tierens, Anne; (...); Abrahamsson, Jonas

Article. 10.1200/JCO.23.01841. 2024


Optimized Cytogenetic Risk-Group Stratification of KMT2A-Rearranged Pediatric Acute Myeloid Leukemia.

van Weelderen, Romy E.; (...); Kaspers, Gertjan J. L.

Article. 10.1182/bloodadvances.2023011771. 2024

  • Open Access.

Outcome after HSCT in Children with JMML from a Historical Point of View

Duarte, ML; (...); Vazquez, GP

Meeting Abstract. 2020


Outcomes of Unmanipulated Haploidentical Transplantation Using Post-Transplant Cyclophosphamide (PT-Cy) in Pediatric Patients With Acute Lymphoblastic Leukemia

Ruggeri, A; (...); Corbacioglu, S

Article. 10.1016/j.jtct.2021.01.016. 2021

  • Open Access.

Treosulfan-Based Conditioning Regimen In Pediatric Hematopoietic Stem Cell Transplantation: A Retrospective Analysis on Behalf of the Spanish Group for Hematopoietic Transplantation and Cellular Therapy (GETH-TC).

Galán V; (...); Pérez-Martínez A

Article. 10.1016/j.jtct.2023.08.016. 2023

  • Open Access.

Use of Eculizumab in Pediatric Patients with High-Risk Transplantation-Associated Thrombotic Microangiopathy: Outcomes and Risk Factors Associated with Response and Survival. A Retrospective Study on Behalf of the Spanish Group for Hematopoietic Transplantation and Cellular Therapy (GETH-TC).

Benítez Carabante MI; (...); Diaz-de-Heredia C

Article. 10.1016/j.jtct.2024.03.019. 2024

  • Open Access.

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