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- Projectes i Estudis Clínics
- ESTUDIO MULTICENTRICO, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO, DE 4 GRUPOS PARALELOS Y 26 SEMANAS DE DURACION PARA EVALUAR LA EFICACIA, SEGURIDAD Y TOLERABILIDAD DE DOS DOSIS ORALES Y DOS REGIMENES DE TIDEGLUSIB VERSUS PLACEBO EN PACIENTES CON ENFERMEDAD DE ALZHEIMER LEVE O MODERADA
ESTUDIO MULTICENTRICO, ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO, DE 4 GRUPOS PARALELOS Y 26 SEMANAS DE DURACION PARA EVALUAR LA EFICACIA, SEGURIDAD Y TOLERABILIDAD DE DOS DOSIS ORALES Y DOS REGIMENES DE TIDEGLUSIB VERSUS PLACEBO EN PACIENTES CON ENFERMEDAD DE ALZHEIMER LEVE O MODERADA
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- NP031112-10B04
- EURDRACT:
- 2010-023322-21
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Resultats de l'Assaig Clínic
[Guidelines for molecular diagnosis of Charcot-Marie-Tooth disease].
Berciano J; (...); Illa I
Abstract of Published Item. 10.1016/j.nrl.2011.04.015. 2012
Amyloid brain-dedicated PET images can diagnose Alzheimer's pathology with Centiloid Scale.
Gandia-Ferrero MT; (...); Martí-Bonmatí L
Article. 10.1016/j.ejmp.2024.103345. 2024
Angiotensin II Receptor Blockers Reduce Tau/ASS42 Ratio: A Cerebrospinal Fluid Biomarkers' Case-Control Study.
Garcia-Lluch, Gemma; (...); Chafer-Pericas, Consuelo
Article. 10.3390/pharmaceutics15030924. 2023
Artificial Intelligence on FDG PET Images Identifies Mild Cognitive Impairment Patients with Neurodegenerative Disease.
Prats-Climent, Joan; (...); Marti-Bonmati, Luis
Article. 10.1007/s10916-022-01836-w. 2022
Assessment of COVID-19 lockdown effect on early Alzheimer Disease progression.
Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo
Article. 10.1007/s00415-023-11899-5. 2023
Assessment of Lipid Peroxidation in Alzheimer's Disease Differential Diagnosis and Prognosis.
Ferre-Gonzalez, Laura; (...); Chafer-Pericas, Consuelo
Article. 10.3390/antiox11030551. 2022
Assessment of Plasma and Cerebrospinal Fluid Biomarkers in Different Stages of Alzheimer's Disease and Frontotemporal Dementia.
Álvarez-Sánchez L; (...); Cháfer-Pericás C
Article. 10.3390/ijms24021226. 2023
Assessment of Screening Approach in Early and Differential Alzheimer's Disease Diagnosis.
Ferré-González L; (...); Cháfer-Pericás C
Article. 10.3390/antiox10111662. 2021
Assessment of Targeted Next-Generation Sequencing as a Tool for the Diagnosis of Charcot-Marie-Tooth Disease and Hereditary Motor Neuropathy
Article. 10.1016/j.jmoldx.2015.10.005. 2016
Associations between antidiabetic medications and cerebrospinal fluid biomarkers of Alzheimer's disease.
Garcia-Lluch, Gemma; (...); Chafer-Pericas, Consuelo
Article. 10.1177/13872877241304995. 2024
Attitudes toward seeking professional help among patients with early Alzheimer's disease
Villarejo-Galende, A.; (...); Maurino, J.
Meeting Abstract. 2023
Autoimmunity as a prognostic factor in sporadic adult onset cerebellar ataxia.
Sivera R; (...); Bataller L
Article. 10.1007/s00415-011-6266-8. 2012
Awareness of Diagnosis in Persons with Early-Stage Alzheimer's Disease: An Observational Study in Spain.
Villarejo-Galende, Alberto; (...); Maurino, Jorge
Article. 10.1007/s40120-022-00367-3. 2022
Cardiovascular Risk Scales Association with Cerebrospinal Fluid Alzheimer's Disease Biomarkers in Cardiovascular Low Cardiovascular Risk Regions.
García-Lluch G; (...); Cháfer-Pericás C
Article. 10.14283/jpad.2024.16. 2024
Clinical features, mutation spectrum and factors related to reaching molecular diagnosis in a cohort of patients with distal myopathies.
Muelas, Nuria; (...); Vilchez, Juan J
Article. 10.1007/s00415-024-12821-3. 2025
Clinical usefulness of cerebrospinal fluid biomarkers in Alzheimer Disease.
Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo
Article. 10.1111/eci.13910. 2022
CMT genetic distribution in Spanish TREAT-CMT consortium
Sivera, R.; (...); Sevilla, T.
Meeting Abstract. 2015
Charcot-Marie-Tooth disease Genetic and clinical spectrum in a Spanish clinical series
Sivera, Rafael; (...); Espinos, Carmen
Article. 10.1212/WNL.0b013e3182a9f56a. 2013
Defining Alzheimer's Disease through Proteomic CSF Profiling.
Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo
Article. 10.1021/acs.jproteome.4c00590. 2024
Depression and Suicide Risk in Mild Cognitive Impairment: The Role of Alzheimer's Disease Biomarkers
Ferrer-Cairols, Ines; (...); Salvador, Alicia
Article. 10.7334/psicothema2022.103. 2022
DEPRESSION IN PATIENTS WITH CHARCOT-MARIE-TOOTH DISEASE TYPE 1A (CMT1A): FINDINGS FROM A REAL-WORLD DIGITAL STUDY
Thomas, Florian; (...); Boutalbi, Youcef
Meeting Abstract. 2022
DESCRIPTION OF A CLUSTER OF PATIENTS WITH THE HSPB1 P.R140G MUTATION
Frasquet, M.; (...); Sevilla, T.
Meeting Abstract. 2016
Diagnostic Efficacy of Genetic Studies in a Series of Hereditary Cerebellar Ataxias in Eastern Spain.
Baviera-Munoz, Raquel; (...); Aller, Elena
Article. 10.1212/NXG.0000000000200038. 2022
Discordant Amyloid Status Diagnosis in Alzheimer's Disease.
García-Vallés L; (...); Cháfer-Pericás C
Article. 10.3390/biomedicines10112880. 2022
Disseminated toxoplasma infection after hematopoietic stem cell transplantation with myositis and encephalitis.
Asensi Cantó P; (...); Guerreiro M
Article. 10.1111/tid.14067. 2023
DRP2 mutations as a cause of Charcot Marie Tooth in Spain
Sivera, R.; (...); Sevilla, T.
Meeting Abstract. 2023
Early Alzheimer's Disease Screening Approach Using Plasma Biomarkers
Alvarez-Sanchez, Lourdes; (...); Chafer-Pericas, Consuelo
Article. 10.3390/ijms241814151. 2023
Emotion recognition and baseline cortisol levels relationship in early Alzheimer Disease.
Ferrer-Cairols, I.; (...); Chafer-Pericas, C.
Article. 10.1016/j.biopsycho.2023.108511. 2023
Epigenomics and Lipidomics Integration in Alzheimer Disease: Pathways Involved in Early Stages.
Peña-Bautista C; (...); Chafer-Pericas, Consuelo
Article. 10.3390/biomedicines9121812. 2021
Expanding the Clinical Spectrum of DRP2-Associated Charcot-Marie-Tooth Disease.
Article. 10.1212/WNL.0000000000209174. 2024
Fast Declining Prediction in Alzheimer's Disease from Early Clinical Assessment.
Álvarez-Sánchez L; (...); Pericás CC
Article. 10.2174/011570159X332930240925095423. 2024
GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 1 MUTATIONS IN SPAIN, A NATIONWIDE STUDY
Sivera, R.; (...); Sevilla, T.
Meeting Abstract. 2016
GENETIC DISTRIBUTION IN THE SPANISH TREAT-CMT CONSORTIUM
Barreiro, M.; (...); Sevilla, T.
Meeting Abstract. 2016
Identification of a novel gene involved in Charcot-Marie-Tooth disease
Sivera, R.; (...); Espinos, C.
Meeting Abstract. 2015
Insights from a 7-Year Dementia Cohort (VALCODIS): ApoE Genotype Evaluation.
Baquero, Miguel; (...); Chafer-Pericas, Consuelo
Article. 10.3390/jcm13164735. 2024
Insights into phenotypic variability caused by GARS1 pathogenic variants.
Jiménez-Jiménez J; (...); Sivera R
Article. 10.1111/ene.16416. 2024
ITPR3-associated neuropathy: Report of a further family with adult onset intermediate Charcot-Marie-Tooth disease.
Cabello-Murgui, Javier; (...); Sivera, Rafael
Article. 10.1111/ene.16485. 2024
Junctophilin-1 is a modifier gene of GDAP1-related Charcot-Marie-Tooth disease
Pla-Martín D; (...); Espinós C
Article. 10.1093/hmg/ddu440. 2015
Late-onset Pompe disease presenting as asymptomatic hyperCKemia and early respiratory impairment
Vilchez, J. J.; (...); Martin, P.
Article. 2012
Lipid Peroxidation Assessment in Preclinical Alzheimer Disease Diagnosis
Pena-Bautista, Carmen; (...); Cháfer-Pericás C
Article. 10.3390/antiox10071043. 2021
Lipids as early and minimally invasive biomarkers for Alzheimer disease.
Casas-Fernandez, Esther; (...); Chafer-Pericas, Consuelo
Article. 10.2174/1570159X19666211102150955. 2021
Long-term outcome in chronic inflammatory demyelinating polyneuropathy patients treated with intravenous immunoglobulin: a retrospective study.
Querol L; (...); Illa I
Article. 10.1002/mus.23843. 2013
Medical help-seeking intentions among patients with early Alzheimer's disease
Villarejo-Galende, Alberto; (...); Maurino, Jorge
Article. 10.3389/fpsyt.2023.1290002. 2023
Misfolded alpha-synuclein detection by RT-QuIC in dementia with lewy bodies: a systematic review and meta-analysis.
Peña-Bautista C; (...); Ferreira D
Article. 10.3389/fmolb.2023.1193458. 2023
Mutations in the MORC2 gene cause axonal Charcot-Marie-Tooth disease
Article. 10.1093/brain/awv311. 2016
New approach for early and specific Alzheimer disease diagnosis from different plasma biomarkers.
Forte, Anabel; (...); Chafer-Pericas, Consuelo
Article. 10.1016/j.cca.2024.117842. 2024
New insights into the genetic etiology of Alzheimer's disease and related dementias
Bellenguez, Celine; (...); CHARGE
Article. 10.1038/s41588-022-01024-z. 2022
Novel Ultrasensitive Detection Technologies for the Identification of Early and Minimally Invasive Alzheimer's Disease Blood Biomarkers.
Alvarez-Sanchez, Lourdes; (...); Chafer-Pericas, Consuelo
Article. 10.3233/JAD-215093. 2022
PATIENT-REPORTED SYMPTOM BURDEN OF CHARCOT-MARIE-TOOTH DISEASE TYPE 1A (CMT1A): FINDINGS FROM A REAL-WORLD DIGITAL STUDY
Thomas, Florian; (...); Boutalbi, Youcef
Meeting Abstract. 2022
Patient-Reported Symptom Burden of Charcot-Marie-Tooth Disease Type 1A: Findings From an Observational Digital Lifestyle Study.
Thomas, Florian P; (...); Boutalbi, Youcef
Article. 10.1097/CND.0000000000000426. 2022
Person-centered Assessment in Early Alzheimers Disease (P1-1.Virtual)
Villarejo Galende, Alberto; (...); Maurino, Jorge
Meeting Abstract. 2022
Plasma Lipidomics Approach in Early and Specific Alzheimer's Disease Diagnosis.
Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo
Article. 10.3390/jcm11175030. 2022
Prognostic value of cerebrospinal fluid biomarkers in mild cognitive impairment due to Alzheimer disease.
Lopez-Cuevas, R; (...); Chafer-Pericas, C
Article. 10.1016/j.nrleng.2020.07.024. 2023
Relationship between neuroimaging and emotion recognition in Mild Cognitive Impairment patients.
Gandia-Ferrero, Maria Teresa; (...); Marti-Bonmati, Luis
Article. 10.1016/j.bbr.2023.114844. 2024
Relationship between Plasma Lipid Profile and Cognitive Status in Early Alzheimer Disease.
Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo
Article. 10.3390/ijms25105317. 2024
Spinocerebellar Ataxia 36 is a Frequent Cause of Hereditary Ataxia in Eastern Spain
Baviera-Munoz, Raquel; (...); Bataller, Luis
Article. 10.1002/mdc3.13740. 2023
The EGR2 gene is involved in axonal Charcot-Marie-Tooth disease
Article. 10.1111/ene.12782. 2015
The natural history of HSJ1-related hereditary neuropathies: a case series of 9 patients with long-term follow-up
Frasquet Carrera, M.; (...); Sevilla, T.
Meeting Abstract. 2015
Vestibular and auditory function in patients with Charcot-Marie-Tooth disease due to mutations in the SH3TC2 gene
Sivera, R.; (...); Sevilla, T.
Article. 2013
Vestibular impairment in Charcot-Marie-Tooth disease type 4C
Pérez-Garrigues H; (...); Sevilla T
Letter. 10.1136/jnnp-2013-307421. 2014
WORK IMPACTS IN PATIENTS WITH CHARCOT-MARIE-TOOTH DISEASE TYPE 1A (CMT1A): FINDINGS FROM A REAL-WORLD DIGITAL STUDY
Thomas, Florian; (...); Boutalbi, Youcef
Meeting Abstract. 2022