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  3. ESTUDIO MULTICENTRICO DE FASE III, ABIERTO, RANDOMIZADO COMPARANDO TRATAMIENTO ADYUVANTE CON IRINOTECAN (CPF-11) MAS 5-FLUOROURACILO (5-FU) EN INFUSION CONTINUA (REGIMEN TTD) FRENTE A OBSERVACION TRAS LA RESECCION DE METASTASIS HEPATICAS EN PACIENTES CONMENOS DE CUATRO METASTASIS HEPATICAS EN EL CANCER COLORRECTAL.

ESTUDIO MULTICENTRICO DE FASE III, ABIERTO, RANDOMIZADO COMPARANDO TRATAMIENTO ADYUVANTE CON IRINOTECAN (CPF-11) MAS 5-FLUOROURACILO (5-FU) EN INFUSION CONTINUA (REGIMEN TTD) FRENTE A OBSERVACION TRAS LA RESECCION DE METASTASIS HEPATICAS EN PACIENTES CONMENOS DE CUATRO METASTASIS HEPATICAS EN EL CANCER COLORRECTAL.

Datos básicos

Código:
XRP4174B/6001
Protocolo:
XRP4174B/6001
EUDRACT:
NO ENCUENTRO
NCT:
Centro:
Dotación:
Año de incio:
Año de finalización:
ENSAYO CLÍNICO

Documentos

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Participantes

Grupos

Financiadores - Promotores

PIVOTAL, SLU.

Resultados del Ensayo Clínico

A microRNA signature for risk-stratification and response prediction to FOLFOX-based adjuvant therapy in stage II and III colorectal cancer.

Okuno, Keisuke; (...); Goel, Ajay

Letter. 10.1186/s12943-022-01699-2. 2023


An exosome-based liquid biopsy predicts depth of response and survival outcomes to cetuximab and panitumumab in metastatic colorectal cancer: The EXONERATE Study.

Xu, Caiming; (...); Goel, Ajay

Article. 10.1158/1078-0432.CCR-24-1934. 2025


Concordance of baseline RAS mutational status (ms) between tissue and cell-free DNA (cfDNA) and association with overall response rate (ORR) in first-line (1L) metastatic colorectal cancer (mCRC) patients (pts): PERSEIDA study (cohort 2) (NCT02792478)

Valladares-Ayerbes, M; (...); Vila, AL

Meeting Abstract. 10.1016/j.annonc.2021.08.976. 2021


Correction: Update on the management of elderly patients with colorectal cancer.

Soler-González G; (...); Gironés-Sarrió R

Correction. 10.1007/s12094-023-03351-x. 2024


Development of a predictive model of venous thromboembolism recurrence in anticoagulated cancer patients using machine learning.

Munoz, Andres J.; (...); Hernandez-Presa, Miguel Angel

Article. 10.1016/j.thromres.2023.06.015. 2023


Dynamic nature of BRAF or KRAS p.G12C mutations in second-line therapy for advanced colorectal cancer patients: do early and late effects exist?

Contreras-Toledo, Debora; (...); Carmona-Bayonas, Alberto

Article. 10.1038/s41416-023-02563-w. 2024


European Association of Urology (EAU) Testicular Cancer Guidelines Panel: A new prognostic factor risk group classification for patients with clinical stage 1 seminoma in active surveillance.

Boormans, Joost; (...); Laguna, Pilar

Meeting Abstract. 2023


Evolution of RAS Mutations in Cell-Free DNA of Patients with Tissue RAS Wild-Type Metastatic Colorectal Cancer Receiving First-Line Treatment: The PERSEIDA Study.

Valladares-Ayerbes M; (...); Lloansí Vila A

Article. 10.3390/cancers14246075. 2022


First-line chemotherapy with or without targeted therapies in metastatic colorectal cancer: The GEMCAD 14-01 prospective cohort

Oliveres, H.; (...); Maurel, J.

Meeting Abstract. 10.1016/j.annonc.2023.09.1796. 2023


Hypertension as predictive factor for bevacizumab-containing first-line therapy in metastatic breast and colorectal cancer in BRECOL (GEICAM/2011-04) study.

Rodríguez-Lescure Á; (...); de la Haba-Rodriguez J

Article. 10.1007/s12094-024-03411-w. 2024


Maintenance of angiogenesis inhibition with aflibercept after progression to bevacizumab in metastatic colorectal cancer: real life study in the Valencian community.

Raga, Mireia Gil; (...); Hernandez, Isabel Busquier

Article. 10.1007/s12094-022-03047-8. 2023


Precision medicine in metastatic colorectal cancer: targeting KRAS G12C mutation

Aparicio, Jorge

Article. 10.21037/tgh-24-28. 2024


Predicting major bleeding events in anticoagulated cancer patients with venous thromboembolism using real-world data and machine learning.

Martin, Andres J. Munoz; (...); Hernandez-Presa, Miguel Angel

Meeting Abstract. 2022


Predicting recurrence of venous thromboembolism in anticoagulated cancer patients using real-world data and machine learning.

Martin, Andres J. Munoz; (...); Hernandez-Presa, Miguel Angel

Meeting Abstract. 2022


Prediction model for major bleeding in anticoagulated patients with cancer-associated venous thromboembolism using machine learning and natural language processing.

Munoz Martin, Andres J; (...); Hernandez-Presa, Miguel Angel

Article. 10.1007/s12094-024-03586-2. 2024


Prognostic Factor Risk Groups for Clinical Stage I Seminoma: An Individual Patient Data Analysis by the European Association of Urology Testicular Cancer Guidelines Panel and Guidelines Office.

Boormans, Joost L; (...); Laguna, M Pilar

Article. 10.1016/j.euo.2023.10.014. 2023


Randomized phase II trial of FOLFIRI-panitumumab compared with FOLFIRI alone in patients with RAS wild-type circulating tumor DNA metastatic colorectal cancer beyond progression to first-line FOLFOX-panitumumab: the BEYOND study (GEMCAD 17-01)

Aparicio, Jorge; (...); Maurel, Joan

Article. 10.1007/s12094-022-02868-x. 2022


Randomized phase II trial of second-line FOLFIRI-panitumumab vs FOLFIRI alone in Ras wild type (wt) metastatic colorectal cancer (mCRC) patients beyond progression to first-line FOLFOX-panitumumab: BEYOND study (GEMCAD 17-01)

Aparicio, J; (...); Maurel, J

Meeting Abstract. 10.1016/j.annonc.2021.08.937. 2021


Real-world dosing patterns of regorafenib for patients with metastatic colorectal cancer in Spain: the RE-SEARCH study.

López Muñoz AM; (...); Martín Gómez T

Article. 10.1007/s12094-024-03630-1. 2024


Retrospective real-world data study using natural language processing to describe treatment sequence and clinicopathological patterns in patients with metastatic colorectal cancer in five Spanish institutions

Vera Garcia, R.; (...); Mondejar Solis, R.

Meeting Abstract. 10.1016/j.annonc.2023.04.343. 2023


SEOM-GEMCAD-TTD clinical guidelines for the systemic treatment of metastatic colorectal cancer (2022).

Fernandez Montes, Ana; (...); Aparicio, Jorge

Article. 10.1007/s12094-023-03199-1. 2023


SEOM-GG clinical guidelines for the management of germ-cell testicular cancer (2023).

Arranz Arija, Jose Angel; (...); Gonzalez-Billalabeitia, Enrique

Article. 10.1007/s12094-024-03532-2. 2024


Sequential RAS mutations evaluation in cell-free DNA of patients with tissue RAS wild-type metastatic colorectal cancer: the PERSEIDA (Cohort 2) study.

Valladares-Ayerbes M; (...); Lloansí Vila A

Article. 10.1007/s12094-024-03487-4. 2024


Update on the management of elderly patients with colorectal cancer.

Soler-Gonzalez, Gemma; (...); Girones-Sarrio, Regina

Article. 10.1007/s12094-023-03243-0. 2023


Venous thromboembolism recurrence during anticoagulant treatment in gastrointestinal cancer patients

Munoz Martin, A.; (...); Angel Hernandez-Presa, M.

Meeting Abstract. 2022


Campos de estudio

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