ESTUDIO EN FASE II DE LA COMBINACION DE DOCETAXEL MAS CISPLATINO EN PACIENTES CON TUMOR DE CELULAS GERMINALES PREVIAMENTE TRATADOS CON POLIQUIMIOTERAPIA ESTANDAR.

Datos básicos

Código:
TAX-ESP-205
Protocolo:
TAX-ESP-205
EUDRACT:
NO PROCEDE
NCT:
Centro:
Dotación:
Año de incio:
Año de finalización:
ENSAYO CLÍNICO

Documentos

  • No hay documentos

Participantes

Financiadores - Promotores

RHONE POULENC-RORER ESPAÑA

Resultados del Ensayo Clínico


A Fibrosis Biomarker Early Predicts Cardiotoxicity Due to Anthracycline-Based Breast Cancer Chemotherapy

de la Fuente, Ana; (...); Ravassa, Susana

Article. 10.3390/cancers14122941. 2022

  • Open Access.

A microRNA signature for risk-stratification and response prediction to FOLFOX-based adjuvant therapy in stage II and III colorectal cancer.

Okuno, Keisuke; (...); Goel, Ajay

Letter. 10.1186/s12943-022-01699-2. 2023

  • Open Access.

A Smart Digital Health Platform to Enable Monitoring of Quality of Life and Frailty in Older Patients with Cancer: A Mixed-Methods, Feasibility Study Protocol.

Papachristou, Nikolaos; (...); Bamidis, Panagiotis D.

Article. 10.1016/j.soncn.2023.151437. 2023

  • Open Access.

An exosome-based liquid biopsy predicts depth of response and survival outcomes to cetuximab and panitumumab in metastatic colorectal cancer: The EXONERATE Study.

Xu, Caiming; (...); Goel, Ajay

Article. 10.1158/1078-0432.CCR-24-1934. 2025


Analysis of Tumor Microenvironment Changes after Neoadjuvant Chemotherapy with or without Bevacizumab in Advanced Ovarian Cancer (GEICO-89T/MINOVA Study).

Tavira B; (...); González-Martín A

Article. 10.1158/1078-0432.CCR-23-0771. 2024

  • Open Access.

Atezolizumab (atezo) combined with platinum-based chemotherapy (CT) and maintenance niraparib for recurrent ovarian cancer (rOC) with a platinum-free interval (TFIp) >6 months: Primary analysis of the double-blind placebo (pbo)controlled ENGOT-Ov41/GEICO 69-O/ANITA phase III trial

Martin, A. Gonzalez; (...); Selle, F.

Meeting Abstract. 10.1016/j.annonc.2023.10.031. 2023

  • Open Access.

Atezolizumab Combined With Platinum and Maintenance Niraparib for Recurrent Ovarian Cancer With a Platinum-Free Interval >6 Months: ENGOT-OV41/GEICO 69-O/ANITA Phase III Trial.

Gonzalez-Martin, Antonio; (...); Selle, Frederic

Article. 10.1200/JCO.24.00668. 2024


Clinical and molecular signature of survival and resistance to olaparib plus pegylated liposomal doxorubicin in platinum-resistant ovarian cancer: a stratified analysis from the phase II clinical trial ROLANDO, GEICO-1601.

Perez-Fidalgo, Jose Alejandro; (...); Gonzalez-Martin, Antonio

Article. 10.1136/ijgc-2022-004028. 2023


Clinical experience with rucaparib after prior PARPi treatment: A subanalysis from the rucaparib access program in Spain by GEICO.

Yubero-Esteban, Alfonso; (...); Sanchez Lorenzo, Maria Luisa

Meeting Abstract. 2022


Clinical insights from the rucaparib access program in Spain: A sub-analysis of long-term responders by GEICO.

Yubero-Esteban, Alfonso; (...); Gonzalez Martin, Antonio

Meeting Abstract. 2022


Concordance of baseline RAS mutational status (ms) between tissue and cell-free DNA (cfDNA) and association with overall response rate (ORR) in first-line (1L) metastatic colorectal cancer (mCRC) patients (pts): PERSEIDA study (cohort 2) (NCT02792478)

Valladares-Ayerbes, M; (...); Vila, AL

Meeting Abstract. 10.1016/j.annonc.2021.08.976. 2021

  • Open Access.

Correction: Update on the management of elderly patients with colorectal cancer.

Soler-González G; (...); Gironés-Sarrió R

Correction. 10.1007/s12094-023-03351-x. 2024

  • Open Access.

Cyclin E cytoplasmatic isoform to predict outcome and benefit to capecitabine treatment in patients with HR+/HER2-metastatic breast cancer from the GEICAM/2013-02 PEARL study

Guerrero, Angel; (...); Martin, Miguel

Meeting Abstract. 2023


Characterization of the gene expression profile of breast cancer tumours in patients undergoing ovarian stimulation for fertility preservation purposes

Soriano, M. J.; (...); Diaz-Garcia, C.

Meeting Abstract. 2022


Development of a predictive model of venous thromboembolism recurrence in anticoagulated cancer patients using machine learning.

Munoz, Andres J.; (...); Hernandez-Presa, Miguel Angel

Article. 10.1016/j.thromres.2023.06.015. 2023


Dynamic nature of BRAF or KRAS p.G12C mutations in second-line therapy for advanced colorectal cancer patients: do early and late effects exist?

Contreras-Toledo, Debora; (...); Carmona-Bayonas, Alberto

Article. 10.1038/s41416-023-02563-w. 2024


European Association of Urology (EAU) Testicular Cancer Guidelines Panel: A new prognostic factor risk group classification for patients with clinical stage 1 seminoma in active surveillance.

Boormans, Joost; (...); Laguna, Pilar

Meeting Abstract. 2023


Evolution of RAS Mutations in Cell-Free DNA of Patients with Tissue RAS Wild-Type Metastatic Colorectal Cancer Receiving First-Line Treatment: The PERSEIDA Study.

Valladares-Ayerbes M; (...); Lloansí Vila A

Article. 10.3390/cancers14246075. 2022

  • Open Access.

First-line chemotherapy with or without targeted therapies in metastatic colorectal cancer: The GEMCAD 14-01 prospective cohort

Oliveres, H.; (...); Maurel, J.

Meeting Abstract. 10.1016/j.annonc.2023.09.1796. 2023


Health-related quality of life (QoL) in platinum-resistant ovarian cancer patients treated with olaparib and pegylated liposomal doxorubicin (PLD), a multicenter single-arm phase II clinical trial (ROLANDO, GEICO-1601).

Alejandro Perez-Fidalgo, Jose; (...); Gonzalez-Martin, Antonio

Meeting Abstract. 10.1200/JCO.2021.39.15_suppl.5549. 2021


Hypertension as predictive factor for bevacizumab-containing first-line therapy in metastatic breast and colorectal cancer in BRECOL (GEICAM/2011-04) study.

Rodríguez-Lescure Á; (...); de la Haba-Rodriguez J

Article. 10.1007/s12094-024-03411-w. 2024

  • Open Access.

Long-term outcomes of high-risk HR-positive and HER2-negative early breast cancer patients from GEICAM adjuvant studies and El Alamo IV registry.

Martin, Miguel; (...); Aguiar-Bujanda, David

Article. 10.1007/s10549-023-07002-1. 2023

  • Open Access.

Lurbinectedin in patients with pretreated endometrial cancer: results from a phase 2 basket clinical trial and exploratory translational study.

Kristeleit, Rebecca; (...); Subbiah, Vivek

Article. 10.1007/s10637-023-01383-2. 2023

  • Open Access.

Lurbinectedin in patients with pretreated neuroendocrine tumours: Results from a phase II basket study.

Longo-Munoz, Federico; (...); Subbiah, Vivek

Article. 10.1016/j.ejca.2022.06.024. 2022

  • Open Access.

Maintenance of angiogenesis inhibition with aflibercept after progression to bevacizumab in metastatic colorectal cancer: real life study in the Valencian community.

Raga, Mireia Gil; (...); Hernandez, Isabel Busquier

Article. 10.1007/s12094-022-03047-8. 2023


Molecular characterization of pregnancy-associated breast cancer and insights on timing from GEICAM-EMBARCAM study.

Pena-Enriquez, Regina; (...); de la Haba-Rodriguez, Juan

Article. 10.1038/s41523-025-00718-x. 2025


Multidisciplinary consensus on the criteria for fertility preservation in cancer patients.

Santaballa, A.; (...); Manau-Trullas, D.

Article. 10.1007/s12094-021-02699-2. 2022

  • Open Access.

Neutrophil-lymphocyte ratio predicts survival in platinum-resistant ovarian cancer patients treated with olaparib and pegylated liposomal doxorubicin (PLD): Stratified analysis from the phase II clinical trial ROLANDO, GEICO-1601

Fidalgo, JAP; (...); Gonzalez-Martin, A

Meeting Abstract. 10.1016/j.annonc.2021.08.1177. 2021

  • Open Access.

Olaparib in combination with pegylated liposomal doxorubicin for platinum-resistant ovarian cancer regardless of BRCA status: a GEICO phase II trial (ROLANDO study)

Perez-Fidalgo, JA; (...); Gonzalez-Martin, A

Article. 10.1016/j.esmoop.2021.100212. 2021

  • Open Access.

Open-label phase II clinical trial of ketoconazole as CYP17 inhibitor in metastatic or advanced non-resectable granulosa cell ovarian tumors: the GREKO (GRanulosa Et KetOconazole) trial, GETHI 2011-03.

Garcia-Donas, Jesus; (...); Grande, Enrique

Article. 10.1007/s12094-023-03085-w. 2023


OReO/ENGOT Ov-38 trial: Impact of maintenance olaparib rechallenge according to ovarian cancer patient prognosis-An exploratory joint analysis of the BRCA and non-BRCA cohorts.

Selle, Frederic; (...); Pujade-Lauraine, Eric

Meeting Abstract. 2022


Overall survival with palbociclib plus endocrine therapy versus capecitabine in postmenopausal patients with hormone receptor-positive, HER2-negative metastatic breast cancer in the PEARL study.

Martin, Miguel; (...); Gil-Gil, Miguel

Article. 10.1016/j.ejca.2022.03.006. 2022

  • Open Access.

Phase II clinical trial assessing the efficacy of enzalutamide in advanced non-resectable granulosa cell ovarian tumors: The GREKO III study (GETHI2016-01).

García-Donas J; (...); Navarro P

Article. 10.1016/j.ygyno.2024.10.019. 2024


Plasma mutational burden in PIK3CA and TP53 independently predicts early progression in patients with HR+/HER2-metastatic breast cancer (MBC) enrolled in the GEICAM/2014-12 FLIPPER trial

Gustavo, Federico; (...); Albanell, Joan

Meeting Abstract. https://doi.org/10.1200/JCO.2024.42.16_suppl.1029. 2024

  • Open Access.

Precision medicine in metastatic colorectal cancer: targeting KRAS G12C mutation

Aparicio, Jorge

Article. 10.21037/tgh-24-28. 2024

  • Open Access.

Predicting major bleeding events in anticoagulated cancer patients with venous thromboembolism using real-world data and machine learning.

Martin, Andres J. Munoz; (...); Hernandez-Presa, Miguel Angel

Meeting Abstract. 2022


Predicting recurrence of venous thromboembolism in anticoagulated cancer patients using real-world data and machine learning.

Martin, Andres J. Munoz; (...); Hernandez-Presa, Miguel Angel

Meeting Abstract. 2022


Prediction model for major bleeding in anticoagulated patients with cancer-associated venous thromboembolism using machine learning and natural language processing.

Munoz Martin, Andres J; (...); Hernandez-Presa, Miguel Angel

Article. 10.1007/s12094-024-03586-2. 2024

  • Open Access.

Prognostic Factor Risk Groups for Clinical Stage I Seminoma: An Individual Patient Data Analysis by the European Association of Urology Testicular Cancer Guidelines Panel and Guidelines Office.

Boormans, Joost L; (...); Laguna, M Pilar

Article. 10.1016/j.euo.2023.10.014. 2023


Quality of life (QoL) with fulvestrant (FUL)/palbociclib (PAL) versus FUL/placebo (PBO) in postmenopausal women with hormone receptor (HR)+/HER2-endocrine sensitive advanced breast cancer (ABC): Results from GEICAM/2014-12 (FLIPPER) study

Tibau, A; (...); Albanell, J

Meeting Abstract. 10.1016/j.annonc.2021.03.108. 2021


Quality of life with palbociclib plus fulvestrant versus placebo plus fulvestrant in postmenopausal women with endocrine-sensitive hormone receptor-positive and HER2-negative advanced breast cancer: patient-reported outcomes from the FLIPPER trial.

Tibau, Ariadna; (...); Albanell, Joan

Article. 10.1177/17588359221148921. 2023

  • Open Access.

Randomized phase II study of fulvestrant plus palbociclib or placebo in endocrine-sensitive, hormone receptor-positive/HER2-advanced breast cancer: GEICAM/2014-12 (FLIPPER).

Albanell, J.; (...); Rojo, F.

Article. 10.1016/j.ejca.2021.11.010. 2022

  • Open Access.

Randomized phase II trial of FOLFIRI-panitumumab compared with FOLFIRI alone in patients with RAS wild-type circulating tumor DNA metastatic colorectal cancer beyond progression to first-line FOLFOX-panitumumab: the BEYOND study (GEMCAD 17-01)

Aparicio, Jorge; (...); Maurel, Joan

Article. 10.1007/s12094-022-02868-x. 2022

  • Open Access.

Randomized phase II trial of second-line FOLFIRI-panitumumab vs FOLFIRI alone in Ras wild type (wt) metastatic colorectal cancer (mCRC) patients beyond progression to first-line FOLFOX-panitumumab: BEYOND study (GEMCAD 17-01)

Aparicio, J; (...); Maurel, J

Meeting Abstract. 10.1016/j.annonc.2021.08.937. 2021

  • Open Access.

Randomized Trial of Cytoreductive Surgery for Relapsed Ovarian Cancer.

Harter P; (...); du Bois A

Article. 10.1056/NEJMoa2103294. 2021

  • Open Access.

Real-world clinical practice patterns and outcomes for advanced ovarian cancer in Spain (GEICO-42-R study)

Redondo, Andres; (...); Gonzalez-Martin, Antonio

Article. 10.31083/j.ejgo4206163. 2021

  • Open Access.

Real-world dosing patterns of regorafenib for patients with metastatic colorectal cancer in Spain: the RE-SEARCH study.

López Muñoz AM; (...); Martín Gómez T

Article. 10.1007/s12094-024-03630-1. 2024


Real-world safety and effectiveness of maintenance niraparib for platinum-sensitive recurrent ovarian cancer: A GEICO retrospective observational study within the Spanish expanded-access programme.

Cueva, Juan F.; (...); Gonzalez-Martin, Antonio

Article. 10.1016/j.ejca.2022.12.023. 2022

  • Open Access.

Retrospective real-world data study using natural language processing to describe treatment sequence and clinicopathological patterns in patients with metastatic colorectal cancer in five Spanish institutions

Vera Garcia, R.; (...); Mondejar Solis, R.

Meeting Abstract. 10.1016/j.annonc.2023.04.343. 2023

  • Open Access.

Role of the receptor for advanced glycation end products (RAGE) in blood as a potential biomarker for progression to olaparib: A post hoc analysis of patients with platinum-resistant ovarian cancer (PROC) treated in the ROLANDO-GEICO 1601 trial

Perez-Fidalgo, Jose Alejandro; (...); Gonzalez-Martin, Antonio

Meeting Abstract. 2024


Rucaparib for PARP inhibitor-pretreated ovarian cancer: A GEICO retrospective subgroup analysis from the Spanish Rucaparib Access Program.

Yubero, Alfonso; (...); Gonzalez-Martin, Antonio

Case Reports. 10.1016/j.gore.2023.101211. 2023

  • Open Access.

Rucaparib in recurrent ovarian cancer: real-world experience from the rucaparib early access programme in Spain - A GEICO study

Yubero, Alfonso; (...); Gonzalez-Martin, Antonio

Article. 10.1186/s12885-022-10191-5. 2022

  • Open Access.

SEOM-GEICO clinical guidelines on endometrial cancer (2021).

Barretina-Ginesta MP; (...); Rubio-Pérez MJ

Article. 10.1007/s12094-022-02799-7. 2022

  • Open Access.

SEOM-GEMCAD-TTD clinical guidelines for the systemic treatment of metastatic colorectal cancer (2022).

Fernandez Montes, Ana; (...); Aparicio, Jorge

Article. 10.1007/s12094-023-03199-1. 2023

  • Open Access.

SEOM-GG clinical guidelines for the management of germ-cell testicular cancer (2023).

Arranz Arija, Jose Angel; (...); Gonzalez-Billalabeitia, Enrique

Article. 10.1007/s12094-024-03532-2. 2024

  • Open Access.

Sequential RAS mutations evaluation in cell-free DNA of patients with tissue RAS wild-type metastatic colorectal cancer: the PERSEIDA (Cohort 2) study.

Valladares-Ayerbes M; (...); Lloansí Vila A

Article. 10.1007/s12094-024-03487-4. 2024

  • Open Access.

The Prognostic Significance of Tumor-Infiltrating Lymphocytes, PD-L1, BRCA Mutation Status and Tumor Mutational Burden in Early-Stage High-Grade Serous Ovarian Carcinoma-A Study by the Spanish Group for Ovarian Cancer Research (GEICO).

Pizarro, David; (...); Palacios, Jose

Article. 10.3390/ijms241311183. 2023

  • Open Access.

Update on the management of elderly patients with colorectal cancer.

Soler-Gonzalez, Gemma; (...); Girones-Sarrio, Regina

Article. 10.1007/s12094-023-03243-0. 2023

  • Open Access.

Use of liquid biomarker thymidine kinase activity (TKa) to predict outcome and progression in patients with metastatic breast cancer (MBC) in the GEICAM/2014-12 FLIPPER trial

Albanell, Joan; (...); Rojo Todo, Federico Gustavo

Meeting Abstract. https://doi.org/10.1200/JCO.2024.42.16_suppl.1028. 2024

  • Open Access.

Venous thromboembolism recurrence during anticoagulant treatment in gastrointestinal cancer patients

Munoz Martin, A.; (...); Angel Hernandez-Presa, M.

Meeting Abstract. 2022


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