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OGMIOS. Sistema Inteligente de apoyo a la toma de decisiones clínicas en medicina de precisión.

Datos básicos

Código:
INNEST/2021/55
Protocolo:
INNEST/2021/55
EUDRACT:
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Dotación:
120.666,00 €
Año de incio:
2021
Año de finalización:
2023
PI BIOMÉDICA AUTONÓMICO Finan. Competitiva Pública

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

AGENCIA VALENCIANA DE LA INNOVACION (AVI)

Resultados del Ensayo Clínico

A NATIONAL PEDIATRIC NEURO-ONCOLOGY TUMOR BOARD INITIATIVE IN SPAIN: RESULTS OF A WEB-BASED SURVEY TO EVALUATE PARTICIPANT EXPERIENCE UTILIZING THIS RESOURCE

Illade, Laura; (...); Lassaletta, Alvaro

Article. 2022


Alectinib in pediatric patients with solid or CNS tumors harboring ALK-fusions: Emerging pharmacokinetic data from the iMATRIX alectinib phase I/II open-label, multi-center study

Doz, Francois; (...); Gajjar, Amar J.

Meeting Abstract. https://doi.org/10.1200/JCO.2024.42.16_suppl.3098. 2024


An International Multi-Center Cohort Study on ß-blockers for the Treatment of Symptomatic Children with Catecholaminergic Polymorphic Ventricular Tachycardia.

Peltenburg PJ; (...); Wilde AAM

Article. 10.1161/CIRCULATIONAHA.121.056018. 2022


ASSESSMENT OF A NOVEL READY-TO-USE TEMOZOLOMIDE ORAL SUSPENSION IN CHILDREN WITH SOLID TUMORS: RESULTS OF TEMOKIDS, A POPULATION PHARMACOKINETIC, ACCEPTABILITY AND SAFETY PHASE-1 STUDY

Abbou, Samuel; (...); Metayer, Lucy

Meeting Abstract. 2023


Association of Left Ventricular Systolic Dysfunction Among Carriers of Truncating Variants in Filamin C With Frequent Ventricular Arrhythmia and End-stage Heart Failure

Akhtar, MM; (...); European Genetic Cardiomyopathies

Article. 10.1001/jamacardio.2021.1106. 2021


Barriers and facilitators to implementation of the interoperable Survivorship Passport (SurPass) v2.0 in 6 European countries: a PanCareSurPass online survey study.

van den Oever, Selina R; (...); Pluijm, Saskia M F

Article. 10.1007/s11764-023-01335-y. 2023


Barriers and facilitators to the implementation of a new European eHealth solution (SurPass v2.0): the PanCareSurPass Open Space study.

de Beijer IAE; (...); Pluijm SMF

Article. 10.1007/s11764-023-01498-8. 2023


Cadmium (Cd) and Lead (Pb) topsoil levels and incidence of childhood leukemias

Asenjo S; (...); Ramis R

Article. 10.1007/s10653-021-01030-w. 2021


Cancer is not a risk factor for severe COVID-19 in children, except in patients with recent allogeneic hematopoietic stem cell transplantation or comorbidities.

Velasco Puyó P; (...); Astigarraga I

Article. 10.1002/pbc.31120. 2024


Case Report: Probable Myocarditis After Covid-19 mRNA Vaccine in a Patient With Arrhythmogenic Left Ventricular Cardiomyopathy.

Alania-Torres, Edgardo; (...); Valle-Munoz, Alfonso

Case Reports. 10.3389/fcvm.2021.759119. 2021


Clinical and molecular characterization of a group of Spanish and German patients with Noonan syndrome

Lopez Gonzalez, Vanesa; (...); Guillen-Navarro, Encarna

Meeting Abstract. 2022


Clinical experience of whole body and tumour dosimetry of 131-I-mIBG treatment for pediatric patients

Espallardo, I. Torres; (...); Prado-Wohlwend, S.

Meeting Abstract. 2023


Clinical Risk Prediction in Patients With Left Ventricular Myocardial Noncompaction

Casas, G; (...); Rodriguez-Palomares, JF

Article. 10.1016/j.jacc.2021.06.016. 2021


Comparative Multicentric Evaluation of Inter-Observer Variability in Manual and Automatic Segmentation of Neuroblastic Tumors in Magnetic Resonance Images

Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis

Article. 10.3390/cancers14153648. 2022


Current status of precision medicine in pediatric oncology in Spain: a consensus report by the Spanish Society of Paediatric Haematology and Oncology (SEHOP).

Gargallo, P.; (...); Moreno, L.

Article. 10.1007/s12094-021-02759-7. 2022


Characterization of Ca2+ handling in induced-pluripotent cardiomyocytes from a CPVT family harbouring the RyR2(R420Q) mutation

Blasco, Almudena Val; (...); Gomez, Ana M.

Meeting Abstract. 2022


Characterization of hereditary transthyretin cardiac amyloidosis in Spain.

Alvarez Rubio, Jorge; (...); AC-TTRv-Spain Investigator Group

Article. 10.1016/j.rec.2021.07.020. 2022


Childhood and Adolescent Central Nervous System Tumours in Spain: Incidence and Survival over 20 Years: A Historical Baseline for Current Assessment.

Chirlaque MD; (...); The Spanish Childhood Cancer Epidemiology Working Group

Article. 10.3390/cancers15245889. 2023


Delving into the clinical impact of NETs in pediatric cancer.

Benavent N; (...); Medina P

Article. 10.1038/s41390-024-03437-4. 2024


ECLIM-SEHOP: how to develop a platform to conduct academic trials for childhood cancer.

Juan-Ribelles A; (...); Fernández-Teijeiro A

Article. 10.1007/s12094-024-03445-0. 2024


Electrocardiographic findings in patients with arrhythmogenic cardiomyopathy and right bundle branch block ventricular tachycardia.

Laredo, Mikael; (...); Belhassen, Bernard

Article. 10.1093/europace/euac267. 2023


Evaluation of circulating tumor DNA by electropherogram analysis and methylome profiling in high-risk neuroblastomas

Trinidad, Eva Maria; (...); de Mora, Jaime Font

Article. 10.3389/fonc.2023.1037342. 2023


Facts and Gaps in Exercise Influence on Arrhythmogenic Cardiomyopathy: New Insights From a Meta-Analysis Approach.

Martínez-Solé J; (...); Zorio E

Review. 10.3389/fcvm.2021.702560. 2021


Frequency and Prognostic Impact of ALK Amplifications and Mutations in the European Neuroblastoma Study Group (SIOPEN) High-Risk Neuroblastoma Trial (HR-NBL1).

Bellini, Angela; (...); Schleiermacher, Gudrun

Article. 10.1200/JCO.21.00086. 2021


Germline Predisposition to Pediatric Cancer, from Next Generation Sequencing to Medical Care.

Gargallo P; (...); Cañete A

Article. 10.3390/cancers13215339. 2021


Germline variant in Ctcf links mental retardation to Wilms tumor predisposition

Gargallo, Pablo; (...); Font de Mora, Jaime

Article. 10.1038/s41431-022-01105-x. 2022


HIGH RISK NEUROBLASTOMA (HR-NB) WITH MNA AND AGE

Ladenstein, Ruth; (...); Canete, Adela

Meeting Abstract. 2023


High risk neuroblastoma (HR-NB) with MNA and age <18 months: Results from the HR-NBL1/SIOPEN trial

Ladenstein, Ruth Lydia; (...); Canete, Adela

Meeting Abstract. 2023


Impact of SARS-CoV-2 infection in patients with cardiac amyloidosis: Results of a multicentre registry.

Larrañaga-Moreira JM; (...); Barriales-Villa R

Article. 10.1016/j.medcli.2023.06.025. 2023


Impact of SARS-Cov-2 infection in patients with hypertrophic cardiomyopathy: results of an international multicentre registry

Gimeno, Juan R.; (...); Lakdawala, Neal K.

Article. 10.1002/ehf2.13964. 2022


Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation

Yin L; (...); Gómez AM

Article. 10.1161/CIRCRESAHA.121.319094. 2021


Importance of genotype for risk stratification in arrhythmogenic right ventricular cardiomyopathy using the 2019 ARVC risk calculator

Protonotarios, Alexandros; (...); Elliott, Perry M.

Article. 10.1093/eurheartj/ehac235. 2022


Independent Validation of a Deep Learning nnU-Net Tool for Neuroblastoma Detection and Segmentation in MR Images

Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis

Article. 10.3390/cancers15051622. 2023


International benchmarking of childhood cancer survival by tumour stage: First results of the BENCHISTA project

Pritchard-Jones, K.; (...); Gatta, G.

Meeting Abstract. 2024


International benchmarking of stage at diagnosis for six childhood solid tumours (the BENCHISTA project): a population-based, retrospective cohort study.

Botta, Laura; (...); Pritchard-Jones, Kathy

Article. 10.1016/S2352-4642(24)00302-X. 2025


IT-Related Barriers and Facilitators to the Implementation of a New European eHealth Solution, the Digital Survivorship Passport (SurPass Version 2.0): Semistructured Digital Survey.

de Beijer, Ismay A E; (...); Chronaki, Catherine

Article. 10.2196/49910. 2024


Lateral-type posterior fossa ependymomas in pediatric population

Miranda-Lloret, Pablo; (...); Llavador, Gemma

Article. 10.1016/j.neucir.2023.10.002. 2024


Lateral-type posterior fossa ependymomas in pediatric population.

Miranda-Lloret, Pablo; (...); Llavador, Gemma

Article. 10.1016/j.neucie.2023.10.001. 2024


Lenvatinib with etoposide plus ifosfamide in patients with refractory or relapsed osteosarcoma (ITCC-050) : a multicentre, open-label, multicohort, phase 1/2 study

Gaspar, N; (...); Campbell-Hewson, Q

Article. 10.1016/S1470-2045(21)00387-9. 2021


Liquidhope: methylome and genomic profiling from very limited quantities of plasma-derived DNA.

Trinidad EM; (...); Font de Mora J

Article. 10.1093/bib/bbac575. 2023


Methodological advances in the discovery of novel neuroblastoma therapeutics.

Segura MF; (...); Moreno L

Article. 10.1080/17460441.2022.2002297. 2022


Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs.

Reinal, Ignacio; (...); Sepulveda, Pilar

Article. 10.3390/antiox12071378. 2023


MR Denoising Increases Radiomic Biomarker Precision and Reproducibility in Oncologic Imaging

Fernández Patón M; (...); Martí-Bonmatí L

Article. 10.1007/s10278-021-00512-8. 2021


MRI and Molecular Characterization of Pediatric High-Grade Midline Thalamic Gliomas: The HERBY Phase II Trial.

Rodriguez D; (...); Jaspan T

Article. 10.1148/radiol.211464. 2022


Natural History of MYH7-related Dilated Cardiomyopathy.

de Frutos, Fernando; (...); Garcia-Pavia, Pablo

Article. 10.1016/j.jacc.2022.07.023. 2022


Neuroblastoma in Spain: Linking the national clinical database and epidemiological registries - A study by the Joint Action on Rare Cancers.

Cañete A; (...); Spanish Neuroblastoma Linkage Working Group (SpNbLinkWG)

Article. 10.1016/j.canep.2022.102145. 2022


Next-Generation Sequencing Identifies Potential Actionable Targets in Paediatric Sarcomas

Ribelles, AJ; (...); Canete, A

Article. 10.3390/jpm11040268. 2021


Non Coding RNAs as Regulators of Wnt/ß-Catenin and Hippo Pathways in Arrhythmogenic Cardiomyopathy

Piquer-Gil, Marina; (...); Zorio, Esther

Review. 10.3390/biomedicines10102619. 2022


Pattern and predictors of sites of relapse in neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project.

Vo, Kieuhoa T.; (...); Matthay, Katherine K.

Article. 10.1002/pbc.29616. 2022


Personalized Medicine in Infant Population with Cancer: Pharmacogenetic Pilot Study of Polymorphisms Related to Toxicity and Response to Chemotherapy.

Urtasun, Andrea; (...); Herrero, Maria Jose

Article. 10.3390/cancers15051424. 2023


Pharmacogenetics in Neuroblastoma: What Can Already Be Clinically Implemented and What Is Coming Next?

Olivera, GG; (...); Herrero, MJ

Review. 10.3390/ijms22189815. 2021


Phase I/II study of single-agent lenvatinib in children and adolescents with refractory or relapsed solid malignancies and young adults with osteosarcoma (ITCC-050) ? .

Gaspar N; (...); Casanova M

Article. 10.1016/j.esmoop.2021.100250. 2021


Polymorphisms in ACE, ACE2, AGTR1 genes and severity of COVID-19 disease.

Sabater Molina, Maria; (...); Gimeno Blanes, Juan R.

Article. 10.1371/journal.pone.0263140. 2022


Prognosis of left ventricular noncompaction with preserved ejection fraction

Casas, G.; (...); Rodriguez-Palomares, J. F.

Meeting Abstract. 2021


Radiotherapy quality assurance in paediatric clinical trials: first report from six QUARTET-affiliated trials.

Kelly, Sarah M.; (...); Mandeville, Henry

Article. 10.1016/j.radonc.2023.109549. 2023


Regorafenib Plus Vincristine and Irinotecan in Pediatric Patients With Recurrent/Refractory Solid Tumors: An Innovative Therapies for Children With Cancer Study.

Casanova M; (...); Geoerger B

Article. 10.1158/1078-0432.CCR-23-0257. 2023


Renin-angiotensin system polymorphisms as potential modifier in COVID-19 outcome

Sabater Molina, Maria; (...); Gimeno Blanes, Juan Ramon

Meeting Abstract. 2022


Reproducibility Analysis of Radiomic Features on T2-weighted MR Images after Processing and Segmentation Alterations in Neuroblastoma Tumors.

Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis

Article. 10.1148/ryai.230208. 2024


Response rate in cardiac resynchronization therapy patients implanted with a left ventricular quadripolar lead and the MultiPoint(TM) Pacing feature activated. QUARTO III.

Osca, Joaquin; (...); Alzueta, Javier

Article. 10.1111/eci.13935. 2022


Retinoblastoma and mosaic 13q deletion: a case report

Gargallo P; (...); Canete, A

Article. 10.1186/s40942-021-00321-9. 2021


Staging childhood cancers in Europe: Application of the Toronto stage principles for neuroblastoma and Wilms tumour. The JARC pilot study.

Gatta G; (...); JARC Pilot Study Toronto Guidelines Working Group

Article. 10.1002/pbc.29020. 2021


Suprarenal Masses in Very Young Infants: Is It Safe to Watch and Wait? Report of a SIOPEN Observational Study Results

Papadakis, Vassilios; (...); Canete, Adela

Article. 10.3390/cancers14164007. 2022


Survival and Health Care Burden of Children With Retinoblastoma in Europe.

Virgili G; (...); Gatta G

Article. 10.1001/jamaophthalmol.2024.4140. 2024


THE BENCHISTA PROJECT: INTERNATIONAL BENCHMARKING OF CHILDHOOD CANCER SURVIVAL BY TUMOUR STAGE

Cortes, Angela Lopez; (...); Pritchard-Jones, Kathy

Article. 2022


The EP300/TP53 pathway, a suppressor of the Hippo and canonical WNT pathways, is activated in human hearts with arrhythmogenic cardiomyopathy in the absence of overt heart failure.

Rouhi L; (...); Marian AJ

Article. 10.1093/cvr/cvab197. 2021


The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries

Alia, Donjeta B.; (...); Nyaywa, Mutale

Article. 10.1016/S2214-109X(22)00250-9. 2022


The prevalence of left and right bundle branch block morphology ventricular tachycardia amongst patients with arrhythmogenic cardiomyopathy and sustained ventricular tachycardia: insights from the European Survey on Arrhythmogenic Cardiomyopathy.

Belhassen, Bernard; (...); Milman, Anat

Article. 10.1093/europace/euab190. 2021


Titin Missense Variants as a Cause of Familial Dilated Cardiomyopathy.

Dominguez, Fernando; (...); Garcia-Pavia, Pablo

Letter. 10.1161/CIRCULATIONAHA.122.062833. 2023


Unraveling the extracellular matrix-tumor cell interactions to aid better targeted therapies for neuroblastoma

Burgos-Panadero, R; (...); Noguera, R

Article. 10.1016/j.ijpharm.2021.121058. 2021


Validation of multiparametric approaches for the prediction of sudden cardiac death in patients with Brugada syndrome and electrophysiological study.

Rodríguez-Mañero M; (...); Arbelo E

Article. 10.1016/j.rec.2021.07.007. 2021


Vitronectin Levels in the Plasma of Neuroblastoma Patients and Culture Media of 3D Models: A Prognostic Circulating Biomarker?

Lopez-Carrasco, Amparo; (...); Noguera, Rosa

Article. 10.3390/ijms25168733. 2024


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