Desarrollo y evaluación de un nuevo tratamiento dirigido y personalizado para neuroblastomas con MYCN amplificado
Datos básicos
- Código:
- ACIF/2021/264
- Protocolo:
- ACIF/2021/264
- EUDRACT:
- NCT:
- Centro:
- Dotación:
- 93.878,00 €
- Año de incio:
- 2021
- Año de finalización:
- 2025
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
A NATIONAL PEDIATRIC NEURO-ONCOLOGY TUMOR BOARD INITIATIVE IN SPAIN: RESULTS OF A WEB-BASED SURVEY TO EVALUATE PARTICIPANT EXPERIENCE UTILIZING THIS RESOURCE
Illade, Laura; (...); Lassaletta, Alvaro
Article. 2022
Alectinib in pediatric patients with solid or CNS tumors harboring ALK-fusions: Emerging pharmacokinetic data from the iMATRIX alectinib phase I/II open-label, multi-center study
Doz, Francois; (...); Gajjar, Amar J.
Meeting Abstract. https://doi.org/10.1200/JCO.2024.42.16_suppl.3098. 2024
ASSESSMENT OF A NOVEL READY-TO-USE TEMOZOLOMIDE ORAL SUSPENSION IN CHILDREN WITH SOLID TUMORS: RESULTS OF TEMOKIDS, A POPULATION PHARMACOKINETIC, ACCEPTABILITY AND SAFETY PHASE-1 STUDY
Abbou, Samuel; (...); Metayer, Lucy
Meeting Abstract. 2023
Barriers and facilitators to the implementation of a new European eHealth solution (SurPass v2.0): the PanCareSurPass Open Space study.
de Beijer IAE; (...); Pluijm SMF
Article. 10.1007/s11764-023-01498-8. 2023
Cancer is not a risk factor for severe COVID-19 in children, except in patients with recent allogeneic hematopoietic stem cell transplantation or comorbidities.
Velasco Puyó P; (...); Astigarraga I
Article. 10.1002/pbc.31120. 2024
Comparative Multicentric Evaluation of Inter-Observer Variability in Manual and Automatic Segmentation of Neuroblastic Tumors in Magnetic Resonance Images
Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis
Article. 10.3390/cancers14153648. 2022
Current status of precision medicine in pediatric oncology in Spain: a consensus report by the Spanish Society of Paediatric Haematology and Oncology (SEHOP).
Gargallo, P.; (...); Moreno, L.
Article. 10.1007/s12094-021-02759-7. 2022
Childhood and Adolescent Central Nervous System Tumours in Spain: Incidence and Survival over 20 Years: A Historical Baseline for Current Assessment.
Chirlaque MD; (...); The Spanish Childhood Cancer Epidemiology Working Group
Article. 10.3390/cancers15245889. 2023
Delving into the clinical impact of NETs in pediatric cancer.
Benavent N; (...); Medina P
Article. 10.1038/s41390-024-03437-4. 2024
ECLIM-SEHOP: how to develop a platform to conduct academic trials for childhood cancer.
Juan-Ribelles A; (...); Fernández-Teijeiro A
Article. 10.1007/s12094-024-03445-0. 2024
Evaluation of circulating tumor DNA by electropherogram analysis and methylome profiling in high-risk neuroblastomas
Trinidad, Eva Maria; (...); de Mora, Jaime Font
Article. 10.3389/fonc.2023.1037342. 2023
Germline Predisposition to Pediatric Cancer, from Next Generation Sequencing to Medical Care.
Gargallo P; (...); Cañete A
Article. 10.3390/cancers13215339. 2021
Germline variant in Ctcf links mental retardation to Wilms tumor predisposition
Gargallo, Pablo; (...); Font de Mora, Jaime
Article. 10.1038/s41431-022-01105-x. 2022
HIGH RISK NEUROBLASTOMA (HR-NB) WITH MNA AND AGE
Ladenstein, Ruth; (...); Canete, Adela
Meeting Abstract. 2023
High risk neuroblastoma (HR-NB) with MNA and age <18 months: Results from the HR-NBL1/SIOPEN trial
Ladenstein, Ruth Lydia; (...); Canete, Adela
Meeting Abstract. 2023
Independent Validation of a Deep Learning nnU-Net Tool for Neuroblastoma Detection and Segmentation in MR Images
Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis
Article. 10.3390/cancers15051622. 2023
International benchmarking of childhood cancer survival by tumour stage: First results of the BENCHISTA project
Pritchard-Jones, K.; (...); Gatta, G.
Meeting Abstract. 2024
International benchmarking of stage at diagnosis for six childhood solid tumours (the BENCHISTA project): a population-based, retrospective cohort study.
Botta, Laura; (...); Pritchard-Jones, Kathy
Article. 10.1016/S2352-4642(24)00302-X. 2025
IT-Related Barriers and Facilitators to the Implementation of a New European eHealth Solution, the Digital Survivorship Passport (SurPass Version 2.0): Semistructured Digital Survey.
de Beijer, Ismay A E; (...); Chronaki, Catherine
Article. 10.2196/49910. 2024
Lateral-type posterior fossa ependymomas in pediatric population
Miranda-Lloret, Pablo; (...); Llavador, Gemma
Article. 10.1016/j.neucir.2023.10.002. 2024
Lateral-type posterior fossa ependymomas in pediatric population.
Miranda-Lloret, Pablo; (...); Llavador, Gemma
Article. 10.1016/j.neucie.2023.10.001. 2024
Liquidhope: methylome and genomic profiling from very limited quantities of plasma-derived DNA.
Trinidad EM; (...); Font de Mora J
Article. 10.1093/bib/bbac575. 2023
Methodological advances in the discovery of novel neuroblastoma therapeutics.
Segura MF; (...); Moreno L
Article. 10.1080/17460441.2022.2002297. 2022
Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs.
Reinal, Ignacio; (...); Sepulveda, Pilar
Article. 10.3390/antiox12071378. 2023
MRI and Molecular Characterization of Pediatric High-Grade Midline Thalamic Gliomas: The HERBY Phase II Trial.
Rodriguez D; (...); Jaspan T
Article. 10.1148/radiol.211464. 2022
Neuroblastoma in Spain: Linking the national clinical database and epidemiological registries - A study by the Joint Action on Rare Cancers.
Cañete A; (...); Spanish Neuroblastoma Linkage Working Group (SpNbLinkWG)
Article. 10.1016/j.canep.2022.102145. 2022
Personalized Medicine in Infant Population with Cancer: Pharmacogenetic Pilot Study of Polymorphisms Related to Toxicity and Response to Chemotherapy.
Urtasun, Andrea; (...); Herrero, Maria Jose
Article. 10.3390/cancers15051424. 2023
Radiotherapy quality assurance in paediatric clinical trials: first report from six QUARTET-affiliated trials.
Kelly, Sarah M.; (...); Mandeville, Henry
Article. 10.1016/j.radonc.2023.109549. 2023
Regorafenib Plus Vincristine and Irinotecan in Pediatric Patients With Recurrent/Refractory Solid Tumors: An Innovative Therapies for Children With Cancer Study.
Casanova M; (...); Geoerger B
Article. 10.1158/1078-0432.CCR-23-0257. 2023
Reproducibility Analysis of Radiomic Features on T2-weighted MR Images after Processing and Segmentation Alterations in Neuroblastoma Tumors.
Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis
Article. 10.1148/ryai.230208. 2024
Suprarenal Masses in Very Young Infants: Is It Safe to Watch and Wait? Report of a SIOPEN Observational Study Results
Papadakis, Vassilios; (...); Canete, Adela
Article. 10.3390/cancers14164007. 2022
Survival and Health Care Burden of Children With Retinoblastoma in Europe.
Virgili G; (...); Gatta G
Article. 10.1001/jamaophthalmol.2024.4140. 2024
THE BENCHISTA PROJECT: INTERNATIONAL BENCHMARKING OF CHILDHOOD CANCER SURVIVAL BY TUMOUR STAGE
Cortes, Angela Lopez; (...); Pritchard-Jones, Kathy
Article. 2022
Tumour growth: An approach to calibrate parameters of a multiphase porous media model based on in vitro observations of Neuroblastoma spheroid growth in a hydrogel microenvironment.
Hervas-Raluy, Silvia; (...); Wall, Wolfgang A.
Article. 10.1016/j.compbiomed.2023.106895. 2023
Vitronectin Levels in the Plasma of Neuroblastoma Patients and Culture Media of 3D Models: A Prognostic Circulating Biomarker?
Lopez-Carrasco, Amparo; (...); Noguera, Rosa
Article. 10.3390/ijms25168733. 2024