Desarrollo y evaluación de un nuevo tratamiento dirigido y personalizado para neuroblastomas con MYCN amplificado

Datos básicos

Código:
ACIF/2021/264
Protocolo:
ACIF/2021/264
EUDRACT:
NCT:
Centro:
Dotación:
93.878,00 €
Año de incio:
2021
Año de finalización:
2025
RRHH AUTONÓMICO Finan. Competitiva Pública

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

CONSELLERIA DE INNOVACIÓN, UNIVERSIDADES, CIENCIA Y SOCIEDAD DIGITAL

Resultados del Ensayo Clínico


A NATIONAL PEDIATRIC NEURO-ONCOLOGY TUMOR BOARD INITIATIVE IN SPAIN: RESULTS OF A WEB-BASED SURVEY TO EVALUATE PARTICIPANT EXPERIENCE UTILIZING THIS RESOURCE

Illade, Laura; (...); Lassaletta, Alvaro

Article. 2022


Alectinib in pediatric patients with solid or CNS tumors harboring ALK-fusions: Emerging pharmacokinetic data from the iMATRIX alectinib phase I/II open-label, multi-center study

Doz, Francois; (...); Gajjar, Amar J.

Meeting Abstract. https://doi.org/10.1200/JCO.2024.42.16_suppl.3098. 2024


ASSESSMENT OF A NOVEL READY-TO-USE TEMOZOLOMIDE ORAL SUSPENSION IN CHILDREN WITH SOLID TUMORS: RESULTS OF TEMOKIDS, A POPULATION PHARMACOKINETIC, ACCEPTABILITY AND SAFETY PHASE-1 STUDY

Abbou, Samuel; (...); Metayer, Lucy

Meeting Abstract. 2023


Barriers and facilitators to the implementation of a new European eHealth solution (SurPass v2.0): the PanCareSurPass Open Space study.

de Beijer IAE; (...); Pluijm SMF

Article. 10.1007/s11764-023-01498-8. 2023


Cancer is not a risk factor for severe COVID-19 in children, except in patients with recent allogeneic hematopoietic stem cell transplantation or comorbidities.

Velasco Puyó P; (...); Astigarraga I

Article. 10.1002/pbc.31120. 2024


Comparative Multicentric Evaluation of Inter-Observer Variability in Manual and Automatic Segmentation of Neuroblastic Tumors in Magnetic Resonance Images

Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis

Article. 10.3390/cancers14153648. 2022


Current status of precision medicine in pediatric oncology in Spain: a consensus report by the Spanish Society of Paediatric Haematology and Oncology (SEHOP).

Gargallo, P.; (...); Moreno, L.

Article. 10.1007/s12094-021-02759-7. 2022


Childhood and Adolescent Central Nervous System Tumours in Spain: Incidence and Survival over 20 Years: A Historical Baseline for Current Assessment.

Chirlaque MD; (...); The Spanish Childhood Cancer Epidemiology Working Group

Article. 10.3390/cancers15245889. 2023


Delving into the clinical impact of NETs in pediatric cancer.

Benavent N; (...); Medina P

Article. 10.1038/s41390-024-03437-4. 2024


ECLIM-SEHOP: how to develop a platform to conduct academic trials for childhood cancer.

Juan-Ribelles A; (...); Fernández-Teijeiro A

Article. 10.1007/s12094-024-03445-0. 2024


Evaluation of circulating tumor DNA by electropherogram analysis and methylome profiling in high-risk neuroblastomas

Trinidad, Eva Maria; (...); de Mora, Jaime Font

Article. 10.3389/fonc.2023.1037342. 2023


Germline Predisposition to Pediatric Cancer, from Next Generation Sequencing to Medical Care.

Gargallo P; (...); Cañete A

Article. 10.3390/cancers13215339. 2021


Germline variant in Ctcf links mental retardation to Wilms tumor predisposition

Gargallo, Pablo; (...); Font de Mora, Jaime

Article. 10.1038/s41431-022-01105-x. 2022


HIGH RISK NEUROBLASTOMA (HR-NB) WITH MNA AND AGE

Ladenstein, Ruth; (...); Canete, Adela

Meeting Abstract. 2023


High risk neuroblastoma (HR-NB) with MNA and age <18 months: Results from the HR-NBL1/SIOPEN trial

Ladenstein, Ruth Lydia; (...); Canete, Adela

Meeting Abstract. 2023


Independent Validation of a Deep Learning nnU-Net Tool for Neuroblastoma Detection and Segmentation in MR Images

Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis

Article. 10.3390/cancers15051622. 2023


International benchmarking of childhood cancer survival by tumour stage: First results of the BENCHISTA project

Pritchard-Jones, K.; (...); Gatta, G.

Meeting Abstract. 2024


International benchmarking of stage at diagnosis for six childhood solid tumours (the BENCHISTA project): a population-based, retrospective cohort study.

Botta, Laura; (...); Pritchard-Jones, Kathy

Article. 10.1016/S2352-4642(24)00302-X. 2025


IT-Related Barriers and Facilitators to the Implementation of a New European eHealth Solution, the Digital Survivorship Passport (SurPass Version 2.0): Semistructured Digital Survey.

de Beijer, Ismay A E; (...); Chronaki, Catherine

Article. 10.2196/49910. 2024


Lateral-type posterior fossa ependymomas in pediatric population

Miranda-Lloret, Pablo; (...); Llavador, Gemma

Article. 10.1016/j.neucir.2023.10.002. 2024


Lateral-type posterior fossa ependymomas in pediatric population.

Miranda-Lloret, Pablo; (...); Llavador, Gemma

Article. 10.1016/j.neucie.2023.10.001. 2024


Liquidhope: methylome and genomic profiling from very limited quantities of plasma-derived DNA.

Trinidad EM; (...); Font de Mora J

Article. 10.1093/bib/bbac575. 2023


Methodological advances in the discovery of novel neuroblastoma therapeutics.

Segura MF; (...); Moreno L

Article. 10.1080/17460441.2022.2002297. 2022


Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs.

Reinal, Ignacio; (...); Sepulveda, Pilar

Article. 10.3390/antiox12071378. 2023


MRI and Molecular Characterization of Pediatric High-Grade Midline Thalamic Gliomas: The HERBY Phase II Trial.

Rodriguez D; (...); Jaspan T

Article. 10.1148/radiol.211464. 2022


Neuroblastoma in Spain: Linking the national clinical database and epidemiological registries - A study by the Joint Action on Rare Cancers.

Cañete A; (...); Spanish Neuroblastoma Linkage Working Group (SpNbLinkWG)

Article. 10.1016/j.canep.2022.102145. 2022


Personalized Medicine in Infant Population with Cancer: Pharmacogenetic Pilot Study of Polymorphisms Related to Toxicity and Response to Chemotherapy.

Urtasun, Andrea; (...); Herrero, Maria Jose

Article. 10.3390/cancers15051424. 2023


Radiotherapy quality assurance in paediatric clinical trials: first report from six QUARTET-affiliated trials.

Kelly, Sarah M.; (...); Mandeville, Henry

Article. 10.1016/j.radonc.2023.109549. 2023


Regorafenib Plus Vincristine and Irinotecan in Pediatric Patients With Recurrent/Refractory Solid Tumors: An Innovative Therapies for Children With Cancer Study.

Casanova M; (...); Geoerger B

Article. 10.1158/1078-0432.CCR-23-0257. 2023


Reproducibility Analysis of Radiomic Features on T2-weighted MR Images after Processing and Segmentation Alterations in Neuroblastoma Tumors.

Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis

Article. 10.1148/ryai.230208. 2024


Suprarenal Masses in Very Young Infants: Is It Safe to Watch and Wait? Report of a SIOPEN Observational Study Results

Papadakis, Vassilios; (...); Canete, Adela

Article. 10.3390/cancers14164007. 2022


Survival and Health Care Burden of Children With Retinoblastoma in Europe.

Virgili G; (...); Gatta G

Article. 10.1001/jamaophthalmol.2024.4140. 2024


THE BENCHISTA PROJECT: INTERNATIONAL BENCHMARKING OF CHILDHOOD CANCER SURVIVAL BY TUMOUR STAGE

Cortes, Angela Lopez; (...); Pritchard-Jones, Kathy

Article. 2022


Tumour growth: An approach to calibrate parameters of a multiphase porous media model based on in vitro observations of Neuroblastoma spheroid growth in a hydrogel microenvironment.

Hervas-Raluy, Silvia; (...); Wall, Wolfgang A.

Article. 10.1016/j.compbiomed.2023.106895. 2023


Vitronectin Levels in the Plasma of Neuroblastoma Patients and Culture Media of 3D Models: A Prognostic Circulating Biomarker?

Lopez-Carrasco, Amparo; (...); Noguera, Rosa

Article. 10.3390/ijms25168733. 2024


Campos de estudio

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