PersonalizeAF. Personalized Therapies for Atrial Fibrillation. A Translational Approach.

Dades bàsiques

Protocol:
860974
EURDRACT:
NCT:
Centre:
Any inici:
2020
Any de finalització:
2024
PI BIOMÉDICA EUROPEA Finan. Competitiva Pública 229.189,00 €

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Participants

Grups d'Investigació

Finançadors - Promotors

COMISION EUROPEA

Resultats de l'Assaig Clínic


Conductive polycaprolactone/gelatin/polyaniline nanofibres as functional scaffolds for cardiac tissue regeneration

Gil-Castell, O.; (...); Ribes-Greus, A.

Article. 10.1016/j.reactfunctpolym.2021.105064. 2022


A Fibrosis Biomarker Early Predicts Cardiotoxicity Due to Anthracycline-Based Breast Cancer Chemotherapy

de la Fuente, Ana; (...); Ravassa, Susana

Article. 10.3390/cancers14122941. 2022

  • Open Access.

Acute Hemodynamic Effects of Simultaneous and Sequential Multi-Point Pacing in Heart Failure Patients With an Expected Higher Rate of Sub-response to Cardiac Resynchronization Therapy: Results of Multicenter SYNSEQ Study.

Sterlinski M; (...); Leyva F

Article. 10.3389/fcvm.2022.901267. 2022

  • Open Access.

Acute performance of stylet driven leads for left bundle branch area pacing: A comparison with lumenless leads

Cano, Oscar; (...); Batul, Syeda Atiqa

Article. 10.1016/j.hroo.2023.11.014. 2023

  • Open Access.

ATR-FTIR spectroscopy for the routine quality control of exosome isolations

Ramos-Garcia, V; (...); Kuligowski, J

Article. 10.1016/j.chemolab.2021.104401. 2021


Atrial low voltage areas: A comparison between atrial fibrillation and sinus rhythm.

Andrés Lahuerta A; (...); Osca, Joaquin

Article. 10.5603/CJ.a2021.0125. 2021

  • Open Access.

Cardiopulmonary Rehabilitation Improves Respiratory Muscle Function and Functional Capacity in Children with Congenital Heart Disease. A Prospective Cohort Study

Ferrer-Sargues FJ; (...); Iranzo, MACI

Article. 10.3390/ijerph17124328. 2020

  • Open Access.

Co-administration of human MSC overexpressing HIF-1a increases human CD34(+) cell engraftment in vivo.

Preciado S; (...); Sánchez-Guijo F

Article. 10.1186/s13287-021-02669-z. 2021

  • Open Access.

Conduction System Pacing for Cardiac Resynchronization Therapy

Cano, Oscar; (...); Martinez-Dolz, Luis

Review. 10.3390/jcdd10110448. 2023

  • Open Access.

Consensus document for anaesthesiologist-assisted sedation in interventional cardiology procedures

Martinez-Dolz, L; (...); Alvarez, J

Article. 10.1016/j.redar.2021.01.001. 2021


Consensus document for anaesthesiologist-assisted sedation in interventional cardiology procedures.

Martinez-Dolz, L; (...); Alvarez, J

Article. 10.1016/j.redare.2021.01.001. 2021


Corrigendum to "Plasmatic Membrane Expression of Adhesion Molecules in Human Cardiac Progenitor/Stem Cells Might Explain Their Superior Cell Engraftment after Cell Transplantation".

Ontoria-Oviedo I; (...); Sepúlveda P

Correction. 10.1155/2022/9786160. 2022

  • Open Access.

Characterization of hiPSC-CMs derived from pediatric cancer patients treated with anthracyclines that suffered cardiotoxicity

Reinal, I.; (...); Sepulveda, P.

Meeting Abstract. 2021


EVs derived from HIF-overexpressing MSC primed with a pro-inflammatory cocktail promote M2 macrophage polarization and reduce fibrosis and endothelium activation in vitro and in a mouse ulcerous colitis model.

Gomez-Ferrer, M.; (...); Sepulveda, P.

Meeting Abstract. 2021


Female gender is an independent predictor of clinical benefit from cardiac resynchronisation therapy - results from the BIOWOMEN study

Van Erven, L.; (...); Zamorano, J. L.

Meeting Abstract. 2023


Genotype FBN1/Phenotype relationship in a cohort of patients with Marfan syndrome.

Hernándiz A; (...); Sepúlveda P

Article. 10.1111/cge.13879. 2020


HIF-1 alpha and Pro-Inflammatory Signaling Improves the Immunomodulatory Activity of MSC-Derived Extracellular Vesicles

Gomez-Ferrer, M; (...); Dorronsoro, A

Article. 10.3390/ijms22073416. 2021

  • Open Access.

HIF-Overexpression and Pro-Inflammatory Priming in Human Mesenchymal Stromal Cells Improves the Healing Properties of Extracellular Vesicles in Experimental Crohn's Disease.

Gómez-Ferrer M; (...); Sepúlveda P

Article. 10.3390/ijms222011269. 2021

  • Open Access.

Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation.

Gómez-Ferrer M; (...); Sepúlveda P

Article. 10.3389/fimmu.2023.1293737. 2023

  • Open Access.

In vitro model of atrial fibrillation: investigating the initiation and maintenance mechanisms of atrial remodeling using hiPSC-derived atrial cardiomyocytes

Casini, M.; (...); Sepulveda, P.

Meeting Abstract. 2023


Influence of baseline inducibility and activation mapping on ablation outcomes in patients with structural heart disease and ventricular tachycardia.

Cano, Oscar; (...); Martinez-Dolz, Luis

Article. 10.1111/jce.15035. 2021

  • Open Access.

Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation.

Dorronsoro, Akaitz; (...); Trigueros, Cesar

Article. 10.1038/s41598-020-78864-4. 2020

  • Open Access.

Isolation and Lipidomic Screening of Human Milk Extracellular Vesicles.

Ramos-Garcia, Victoria; (...); Kuligowski, Julia

Article. 10.1007/978-1-0716-2699-3_18. 2023


Isolation of extracellular vesicles derived from mesenchymal stem cells by ultracentrifugation and tangential flow filtration followed by size-exclusion chromatography: a functional comparison

Amaro-Prellezo, E.; (...); Sepulveda, P.

Meeting Abstract. 2021


Left bundle branch pacing versus left ventricular septal pacing as a primary procedural endpoint during left bundle branch area pacing: Evaluation of two different implant strategies.

Cano, Oscar; (...); Martinez-Dolz, Luis

Article. 10.1111/jce.16128. 2023


miR-4732-3p in Extracellular Vesicles From Mesenchymal Stromal Cells Is Cardioprotective During Myocardial Ischemia

Sánchez-Sánchez R; (...); Sepúlveda P

Article. 10.3389/fcell.2021.734143. 2021

  • Open Access.

miRNA-4732-3p as a possible therapeutic tool for the treatment of myocardial ischemia

Sanchez-Sanchez, R.; (...); Sepulveda, P.

Meeting Abstract. 2021


Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs.

Reinal, Ignacio; (...); Sepulveda, Pilar

Article. 10.3390/antiox12071378. 2023

  • Open Access.

Modeling Transposition of the Great Arteries with Patient-Specific Induced Pluripotent Stem Cells.

Ontoria-Oviedo, Imelda; (...); Sepulveda, Pilar

Article. 10.3390/ijms222413270. 2021

  • Open Access.

Multicenter prospective comparison of conventional and high-power short duration radiofrequency application for pulmonary vein isolation: the high-power short-duration radiofrequency application for faster and safer pulmonary vein ablation (POWER FAST III) trial.

Castrejon-Castrejon, Sergio; (...); Merino, Jose Luis

Article. 10.1007/s10840-023-01509-9. 2023


Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds.

Verheijen, Marcha; (...); HeCaToS Consortium

Article. 10.1038/s41597-022-01825-1. 2022

  • Open Access.

Non-classical Notch signaling by MDA-MB-231 breast cancer cell-derived small extracellular vesicles promotes malignancy in poorly invasive MCF-7 cells.

Gonzalez-King, Hernan; (...); Garcia, Nahuel A.

Article. 10.1038/s41417-021-00411-8. 2022


Oncostatin M-Enriched Small Extracellular Vesicles Derived from Mesenchymal Stem Cells Prevent Isoproterenol-Induced Fibrosis and Enhance Angiogenesis.

Tejedor, Sandra; (...); Sepulveda, Pilar

Article. 10.3390/ijms24076467. 2023

  • Open Access.

Optimization of Mesenchymal Stromal Cell (MSC) Manufacturing Processes for a Better Therapeutic Outcome

Fernandez-Santos, Maria Eugenia; (...); Zapata, Agustin G.

Article. 10.3389/fimmu.2022.918565. 2022

  • Open Access.

Outcomes of leadless pacemaker implantation in patients with mechanical heart valves

Loughlin, G.; (...); Arias, M. A.

Meeting Abstract. 2021


OUTCOMES OF LEADLESS PACEMAKER IMPLANTATION IN PATIENTS WITH MECHANICAL HEART VALVES.

Loughlin G; (...); Miguel A A

Article. 10.1111/jce.15462. 2022


Over-Expression of HIF-1A In Mesenchymal Stromal Cells Increases Human CD34+Cells Clonogenic Capacity in Vitro And Engraftment Ability in A Xenotransplantation Model

Preciado, S; (...); Sanchez-Guijo, F

Meeting Abstract. 2021


Personalized assessment of the cumulative complication risk of the atrial fibrillation ablation track: The AF-TRACK calculator.

Bisbal, Felipe; (...); de Greef, Yves

Article. 10.1016/j.hroo.2022.07.013. 2022

  • Open Access.

Pharmacological senolysis reduces doxorubicin-induced cardiotoxicity and improves cardiac function in mice.

Lerida-Viso, Araceli; (...); Martinez-Manez, Ramon

Article. 10.1016/j.phrs.2022.106356. 2022

  • Open Access.

Plasmatic Membrane Expression of Adhesion Molecules in Human Cardiac Progenitor/Stem Cells Might Explain Their Superior Cell Engraftment after Cell Transplantation.

Ontoria-Oviedo I; (...); Sepúlveda P

Article. 10.1155/2020/8872009. 2020

  • Open Access.

Platelet rich plasma and plasma rich in growth factors for split-thickness skin graft donor site treatment in the burn patient setting: A randomized clinical trial.

García-Sánchez JM; (...); Pérez-Del-Caz MD

Article. 10.1016/j.burns.2021.10.001. 2021


Polymer Conjugation of Docosahexaenoic Acid Potentiates Cardioprotective Therapy in Preclinical Models of Myocardial Ischemia/Reperfusion Injury.

Tejedor S; (...); Vicent MJ

Article. 10.1002/adhm.202002121. 2021


Priorities in Cardio-Oncology Basic and Translational Science: GCOS 2023 Symposium Proceedings: JACC: CardioOncology State-of-the-Art Review.

Salloum FN; (...); López-Fernández T

Article. 10.1016/j.jaccao.2023.08.003. 2023

  • Open Access.

Prognostic value and clinical predictors of intramyocardial hemorrhage measured by CMR T2* sequences in STEMI.

Ferré-Vallverdú M; (...); Igual-Muñoz B

Article. 10.1007/s10554-020-02142-7. 2021


Reliable assessment of carbon black nanomaterial of a variety of cell culture media for in vitro toxicity assays by asymmetrical flow field-flow fractionation.

Boughbina-Portoles, Aaron; (...); Campins-Falco, Pilar

Article. 10.1007/s00216-023-04597-8. 2023

  • Open Access.

Response rate in cardiac resynchronization therapy patients implanted with a left ventricular quadripolar lead and the MultiPoint(TM) Pacing feature activated. QUARTO III.

Osca, Joaquin; (...); Alzueta, Javier

Article. 10.1111/eci.13935. 2022


Safety and feasibility of conduction system pacing in patients with congenital heart disease

Cano, O; (...); Vijayaraman, P

Article. 10.1111/jce.15213. 2021

  • Open Access.

Short-Time Estimation of Fractionation in Atrial Fibrillation with Coarse-Grained Correlation Dimension for Mapping the Atrial Substrate

Vraka A; (...); Rieta JJ

Article. 10.3390/e22020232. 2020

  • Open Access.

Spanish Implantable Cardioverter-defibrillator Registry. 16th Official Report of the Heart Rhythm Association of the Spanish Society of Cardiology (2019).

Fernandez Lozano, Ignacio, Osca Asensi, Joaquin, Alzueta Rodriguez, Javier

Article. 10.1016/j.recesp.2020.07.032. 2020


Spanish Implantable Cardioverter-defibrillator Registry. 17th Official Report of the Heart Rhythm Association of the Spanish Society of Cardiology (2020)

Fernandez Lozano, Ignacio, Osca Asensi, Joaquin, Alzueta Rodriguez, Javier

Article. 10.1016/j.recesp.2021.07.003. 2021

  • Open Access.

Spanish Implantable Cardioverter-defibrillator Registry. 17th Official Report of the Heart Rhythm Association of the Spanish Society of Cardiology (2020).

Fernandez Lozano, Ignacio, Osca Asensi, Joaquin, Alzueta Rodriguez, Javier

Article. 10.1016/j.rec.2021.09.002. 2021


Spanish implantable cardioverter-defibrillator registry. 18th official report of the Heart Rhythm Association of the Spanish Society of Cardiology (2021).

Fernández Lozano I, Osca Asensi J, Alzueta Rodríguez J

Article. 10.1016/j.rec.2022.09.007. 2022


Spanish implantable cardioverter-defibrillator registry. 19th official report of Heart Rhythm Association of the Spanish Society of Cardiology (2022).

Fernandez Lozano, Ignacio, Osca Asensi, Joaquin, Alzueta Rodriguez, Javier

Article. 10.1016/j.rec.2023.06.015. 2023

  • Open Access.

Subtype-specific differentiation of atrial and ventricular cardiomyocytes from human iPSCs

Casini, M.; (...); Sepulveda, P.

Meeting Abstract. 2021


The RITHMI study: diagnostic ability of a heart rhythm monitor for automatic detection of atrial fibrillation.

Osca Asensi, Joaquin; (...); Martinez Dolz, Luis

Article. 10.1016/j.recesp.2020.05.006. 2020


The Vascular Niche for Adult Cardiac Progenitor Cells.

Herrero, Diego; (...); Bernad, Antonio

Article. 10.3390/antiox11050882. 2022

  • Open Access.

Topical Administration of a Marine Oil Rich in Pro-Resolving Lipid Mediators Accelerates Wound Healing in Diabetic db/db Mice through Angiogenesis and Macrophage Polarization.

Ontoria-Oviedo, Imelda; (...); Sepulveda, Pilar

Article. 10.3390/ijms23179918. 2022

  • Open Access.

Two-component Peptidic Molecular Gels for Topical Drug Delivery of Naproxen

Martí-Centelles, Rosa; (...); Escuder, Beatriu

Article. 10.1021/acsabm.0c01422. 2021


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