Portal de investigación
- Inicio
- Proyectos y Estudios
- ESTUDIO ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO Y DE GRUPOS PARALELOS CON UNA FASE DE EXTENSION ABIERTA PARA EVALUAR EL EFECTO DE PERAMPANEL (E2007) EN LA COGNICION, EL CRECIMIENTO, LA SEGURIDAD, LA TOLERABILIDAD Y LA FARMACOCINETICA CUANDO SE A DMINISTRA COMO TERAPIA ADYUVANTE EN ADOLESCENTES ( DE 12 A MENOS DE 18 AÑOS DE EDAD) CON CRISIS DE INICIO PARCIAL INSUFICIENTEMENTE CONTROLADAS.
ESTUDIO ALEATORIZADO, DOBLE CIEGO, CONTROLADO CON PLACEBO Y DE GRUPOS PARALELOS CON UNA FASE DE EXTENSION ABIERTA PARA EVALUAR EL EFECTO DE PERAMPANEL (E2007) EN LA COGNICION, EL CRECIMIENTO, LA SEGURIDAD, LA TOLERABILIDAD Y LA FARMACOCINETICA CUANDO SE A DMINISTRA COMO TERAPIA ADYUVANTE EN ADOLESCENTES ( DE 12 A MENOS DE 18 AÑOS DE EDAD) CON CRISIS DE INICIO PARCIAL INSUFICIENTEMENTE CONTROLADAS.
Datos básicos
- Protocolo:
- E2007-G000-235
- EUDRACT:
- 2010-018518-56
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Año de incio:
- 2011
- Año de finalización:
- 2014
Objetivos del proyecto
Observaciones: Estado Comité: FINALIZADO
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
A survey of the European Reference Network EpiCARE on clinical practice for selected rare epilepsies.
Baumgartner T; (...); Sadowski K
Article. 10.1002/epi4.12459. 2021
Aplicación de la farmacoeconomía en la gestión clínica.
Amat Díaz M, Poveda Andrés JL, Carrera-Hueso FJ
Article. 10.1016/S1130-6343(11)70018-6. 2011
Assessment of the effectiveness and safety of natalizumab for treating relapsing-remitting multiple sclerosis.
Fernández-Megía MJ; (...); Poveda-Andrés JL
Article. 10.1016/j.farma.2010.02.003. 2011
Assessment of the in vivo formation of biofilm on external ventricular drainages.
Ramírez P; (...); Bonastre J
Article. 10.1007/s10096-013-1895-8. 2013
Cannabidiol therapy for refractory epilepsy in paediatric real world setting: What's the benefit?
Smeyers, P.; (...); Hernandez, S.
Meeting Abstract. 2024
Cognitive adverse events of adjunctive eslicarbazepine acetate in children with refractory focal seizures
Smeyers, P.; (...); Gama, H.
Meeting Abstract. 2022
Cognitive and Behavioral Effects of Adjunctive Brivaracetam in Children and Adolescents with Focal Seizures: Final Data From an Open-label Follow-up Trial
Elshoff, Jan-Peer; (...); Smeyers, Patricia
Meeting Abstract. 10.1212/WNL.0000000000201877. 2023
Combination of Corpus Callosotomy and Vagus Nerve Stimulation in the Treatment of Refractory Epilepsy
Guillamon, E; (...); Villanueva, V
Article. 10.1159/000353979. 2014
Cost-effectiveness of buccal midazolam in the treatment of prolonged convulsive seizures in the outpatient setting in Spain
Raspall-Chaure, M; (...); Cebollero, MA
Article. 10.33588/rn.5811.2014057. 2014
EFFECT OF CYP3A5 GENOTYPE ON TACROLIMUS DOSE REQUIREMENT, NEPHROTOXICITY AND ACUTE REJECTION IN KIDNEY TRANSPLANTATION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF OBSERVATIONAL STUDIES
Rojas, L.; (...); Alino, S. F.
Article. 2013
EFFECTS OF POLYMORPHIMS OF CYP3A5 AND ABCB1 GENES ON CHRONIC NEPHROPATHY: COHORT STUDY
Rojas, L.; (...); Alino, S. F.
Article. 2013
EFFICACY AND SAFETY OF PERAMPANEL AS ADJUNCTIVE THERAPY IN ADOLESCENTS WITH REFRACTORY PARTIAL-ONSET SEIZURES: ANALYSIS OF A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE III STUDY
Villanueva, V.; (...); Laurenza, A.
Article. 2011
Estudio de utilizacion de boceprevir y telaprevir para el tratamiento de la hepatitis C cronica.
Marrero-Álvarez P; (...); Poveda-Andrés JL
Abstract of Published Item. 10.7399/FH.2014.38.1.1128. 2014
Increased hospital stay and allograft dysfunction in renal transplant recipients with Cyp2c19 AA variant in SNP rs4244285.
Bosó V; (...); Aliño SF
Article. 10.1124/dmd.112.047977. 2013
Meta-analysis and systematic review of the effect of the donor and recipient CYP3A5 6986A>G genotype on tacrolimus dose requirements in liver transplantation.
Rojas LE; (...); Aliño SF
Article. 10.1097/FPC.0b013e3283642fb3. 2013
Mitochondrial developmental encephalopathy with bilateral optic neuropathy related to homozygous variants in IMMT gene.
Marco-Hernández AV; (...); Martínez-Castellano F
Article. 10.1111/cge.14093. 2022
Monitorización de errores de medicación en dispensación individualizada mediante el método del carro centinela.
Pérez-Cebrián M; (...); Poveda-Andrés JL
Abstract of Published Item. 10.1016/j.farma.2010.06.004. 2011
Paclitaxel and carboplatin treatment for advanced ovarian cancer during pregnancy.
Ruiz Ramos J; (...); Poveda JL
Article. 10.1159/000360691. 2013
Papel del acetato de eslicarbazepina en el tratamiento de la epilepsia de origen focal en la edad pediátrica: consideraciones prácticas.
García-Peñas JJ; (...); Aparicio J
Review. 10.33588/rn.71s01.2020562. 2020
Peripheral nerve hyperexcitability: a clinical and immunologic study of 38 patients.
Ramírez P; (...); Bataller L
Article. 10.1212/WNL.0b013e3182061b1e. 2011
Renal Transplantation Recipients with AA Genotype in SNP rs4244285 of CYP2C19 Show An Increase in Hospital Stay Duration and Allograft Dysfunction Probably Due to Increased Tacrolimus Levels Caused by Interaction with Omeprazol
Boso, V; (...); Alino, S. F.
Article. 10.1097/00007890-201211271-01757. 2012
Selective ophthalmic intra-arterial melphalan therapy for advanced retinoblastoma: implementation and outcomes of a new chemotherapy protocol.
Valero García S; (...); Poveda Andrés JL
Article. 10.1177/1078155212457964. 2013
Severe Communication Delays Are Independent of Seizure Burden and Persist Despite Contemporary Treatments in SCN1A+ Dravet Syndrome: Insights from the ENVISION Natural History Study.
Perry, M. Scott; (...); Rico, Salvador
Article. 10.1111/epi.17850. 2023
SNPs and taxane toxicity in breast cancer patients
Bosó V; (...); Aliño SF
Article. 10.2217/PGS.14.127. 2014
Treatment adherence and other patient-reported outcomes as cost determinants in multiple sclerosis: a review of the literature
Lizan, L; (...); Polanco, C
Review. 10.2147/PPA.S67253. 2014
Triplication of the PCDH19 Gene as a Novel Disease Mechanism Leading to Epileptic Encephalopathy Resembling Loss-of-Function Pathogenic Variants.
Gabaldón-Albero A; (...); Martínez F
Article. 10.3390/genes15101312. 2024
Uso benzodiacepinas en crisis prolongadas y estado epileptico en la comunidad.
Sanchez-Carpintero R; (...); Cebollero MA
Article. 10.1016/j.anpedi.2014.03.023. 2014