Portal de investigación
ESTUDIO DE FASE II ABIERTO, ALEATORIZADO, DE EC145 EN MONOTERAPIA Y LA COMBINACIÓN DE EC145 MÁS DOCETAXEL FRENTE A DOCETAXEL SOLO EN PARTICIPANTES CON CPCNP POSITIVO A RECEPTORES DE FOLATO [FR(++)] EN SEGUNDA LÍNEA.
Datos básicos
- Protocolo:
- EC-FV-07
- EUDRACT:
- 2012-000966-40
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Año de incio:
- 2013
- Año de finalización:
- 2015
Objetivos del proyecto
Observaciones: Estado Comité: FINALIZADO
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
[Detection of dysphagia in the institutionalised elderly].
Ferrero Lopez, Maria Isabel; (...); Juan Vidal, Oscar
Article. 10.1016/j.regg.2011.09.004. 2012
Adjuvant therapy with bemiparin in patients with limited-stage small cell lung cancer: results from the ABEL study.
Lecumberri R; (...); Rocha E
Article. 10.1016/j.thromres.2013.09.026. 2013
Advantages of one step nucleic acid amplification (OSNA) whole node assay in sentinel lymph node (SLN) analysis in breast cancer
Santaballa, Ana; (...); Bello, Pilar
Article. 10.1186/2193-1801-2-542. 2013
Analisis de las causas de suspension de tratamiento con triple terapia antiviral en pacientes con hepatitis C.
Ruiz Ramos J; (...); Poveda Andrés JL
Abstract of Published Item. 10.7399/fh.2014.38.3.1171. 2014
Anidulafungin-Induced Alopecia
Ruiz-Ramos J; (...); Poveda-Andrés JL
Article. 10.1177/1060028014524534. 2014
Association of SNPs with the efficacy and safety of immunosuppressant therapy after heart transplantation
Sánchez-Lázaro I; (...); Aliño SF
Article. 10.2217/pgs.15.39. 2015
Biosimilares: viejas polemicas con nuevos argumentos.
Poveda-Andrés JL, Bosó-Ribelles V
Editorial Material. 10.7399/fh.2015.39.3.8978. 2015
Calidad y Legibilidad de la Hoja de Informacion al Paciente en Estudios con Analisis Farmacogenetico.
Ruiz Ramos J; (...); Poveda Andrés JL
Article. 2015
Clinical experiences with cannabinoids in spasticity management in multiple sclerosis
Lorente Fernández L; (...); Casanova-Estruch B
Article. 10.1016/j.nrl.2013.06.014. 2014
Consolidation treatment with Yttrium-90 ibritumomab tiuxetan after new induction regimen in patients with intermediate- and high-risk follicular lymphoma according to the follicular lymphoma international prognostic index: a multicenter, prospective phase II trial of the Spanish Lymphoma Oncology Group
Provencio M; (...); Gotel (Spanish Lymphoma Oncology Group)
Article. 10.3109/10428194.2013.790544. 2014
Cost-effectiveness of methoxy polyethylene glycolepoetin beta versus conventional epoetin in the treatment of anaemia secondary to chronic kidney disease in clinical practice
Lorente-Fernandez, L; (...); Poveda-Andres, JL
Article. 10.1136/ejhpharm-2013-000426. 2015
Drug Interaction Between Oral Cyclosporine Modified and Iron
Domingo-Chiva, E; (...); Poveda-Andres, JL
Article. 10.1177/1060028013514734. 2014
ECONOMIC IMPACT LINKED TO THE REDUCTION OF EXACERBATIONS WHEN A TREATMENT REGIME WITH INHALED ANTIBIOTICS IS SWITCHED TO AZTREONAM LYSINE IN PATIENTS WITH CYSTIC FIBROSIS AND CHRONIC PULMONARY INFECTION CAUSED BY PSEUDOMONAS AERUGINOSA
Sole A; (...); Casado MA
Meeting Abstract. 10.1016/j.jval.2014.08.1659. 2014
EFFECT OF CYP3A5 GENOTYPE ON TACROLIMUS DOSE REQUIREMENT, NEPHROTOXICITY AND ACUTE REJECTION IN KIDNEY TRANSPLANTATION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF OBSERVATIONAL STUDIES
Rojas, L.; (...); Alino, S. F.
Article. 2013
Effect of CYP3A5*3 on kidney transplant recipients treated with tacrolimus: a systematic review and meta-analysis of observational studies
Rojas L; (...); Aliño SF
Article. 10.1038/tpj.2014.38. 2015
EFFECTS OF POLYMORPHIMS OF CYP3A5 AND ABCB1 GENES ON CHRONIC NEPHROPATHY: COHORT STUDY
Rojas, L.; (...); Alino, S. F.
Article. 2013
Estimation of the elastic parameters of human liver biomechanical models by means of medical images and evolutionary computation.
Martínez-Martínez F; (...); López-Andújar R
Article. 10.1016/j.cmpb.2013.05.005. 2013
Estudio de utilizacion de boceprevir y telaprevir para el tratamiento de la hepatitis C cronica.
Marrero-Álvarez P; (...); Poveda-Andrés JL
Abstract of Published Item. 10.7399/FH.2014.38.1.1128. 2014
Experience in the management of immunosuppressant treatment with hepatitis C virus protease inhibitors
Ruiz Ramos J; (...); Poveda Andrés JL
Article. 10.1016/j.gastrohep.2014.05.004. 2014
Feasibility and Safety of a Modified Outpatient Regimen With Intravenous/Intraperitoneal Chemotherapy for Optimally Debulked Stage III Ovarian Cancer
Bruixola G; (...); Santaballa A
Article. 10.1097/IGC.0000000000000330. 2015
Full-dose Cisplatin and Oral Vinorelbine Concomitant with Radiotherapy in Unresectable Stage III Non-small Cell Lung Cancer: A Multi-center Phase II Study
Juan O; (...); Giner V
Article. 2014
Genotype and Allele Frequencies of Drug-Metabolizing Enzymes and Drug Transporter Genes Affecting Immunosuppressants in the Spanish White Population
Bosó V; (...); Aliño SF
Article. 10.1097/FTD.0b013e3182a94e65. 2014
Heart failure as first sign of development of cardiac metastases in a patient with diagnosis of papillary thyroid carcinoma on treatment with tyrosine-kinase inhibitors: differential diagnoses and clinical management.
Bruixola G; (...); Díaz-Beveridge R
Article. 10.1159/000366192. 2014
Helicobacter pylori second-line rescue therapy with levofloxacin- and bismuth-containing quadruple therapy, after failure of standard triple or non-bismuth quadruple treatments
Gisbert JP; (...); McNicholl AG
Article. 10.1111/apt.13128. 2015
High serum levels of vascular endothelial growth factor-C have a positive impact on outcome of patients with advanced diffuse large B cell lymphoma
Rueda A; (...); Spanish Lymphoma Oncology Group
Letter. 10.3109/10428194.2013.836601. 2014
Incompatibility of undiluted busulfan injection with a needle-free valve
Cueto-Sola, M; (...); Poveda-Andres, JL
Letter. 10.2146/ajhp140111. 2014
Increased hospital stay and allograft dysfunction in renal transplant recipients with Cyp2c19 AA variant in SNP rs4244285.
Bosó V; (...); Aliño SF
Article. 10.1124/dmd.112.047977. 2013
Influence of ABCB1 polymorphisms upon the effectiveness of standard treatment for acute myeloid leukemia: A systematic review and meta-analysis of observational studies
Megías-Vericat JE; (...); Aliño SF
Review. 10.1038/tpj.2014.80. 2015
Intercalated Dosing Schedule of Erlotinib and Docetaxel as a Therapeutic Strategy to Avoid Antagonism and Optimize Its Benefits in Advanced Non-Small-Cell Lung Cancer. A Randomized Phase II Clinical Trial
Juan Ó; (...); Giner V
Article. 10.1016/j.cllc.2014.11.006. 2015
Meta-analysis and systematic review of the effect of the donor and recipient CYP3A5 6986A>G genotype on tacrolimus dose requirements in liver transplantation.
Rojas LE; (...); Aliño SF
Article. 10.1097/FPC.0b013e3283642fb3. 2013
Metaiodobenzylguanidine and Neuroblastoma
Balaguer, J; (...); Castel, V
Review. 10.1055/s-0036-1572362. 2015
Neumorraquis y neumomediastino espontaneo, rara complicacion asmatica.
Fernandez Garcia C; (...); Gomez J
Article. 10.1016/j.anpedi.2014.11.008. 2015
Paclitaxel and carboplatin treatment for advanced ovarian cancer during pregnancy.
Ruiz Ramos J; (...); Poveda JL
Article. 10.1159/000360691. 2013
Pleuropulmonary angiosarcoma involving the liver, the jejunum and the spine, developed from chronic tuberculosis pyothorax: Multidisciplinary approach and review of literature
Bruixola G; (...); Aparicio J
Review. 10.1016/j.lungcan.2014.07.012. 2014
Prevalence of EGFR mutations in newly diagnosed locally advanced or metastatic non-small cell lung cancer Spanish patients and its association with histological subtypes and clinical features: The Spanish REASON study
Esteban, E.; (...); Provencio, M.
Article. 10.1016/j.canep.2015.02.003. 2015
Prognostic Impact of Anthracycline Metabolism Gene Polymorphisms in Newly Diagnosed Acute Myeloid Leukemia Adults
Eduardo Megias, Juan; (...); Angel Sanz, Miguel
Article. 2014
Prognostic Impact of Cytarabine Pathway Gene Polymorphisms in Acute Myeloid Leukemia Adults Undergoing Induction Chemotherapy
Eduardo Megias, Juan; (...); Angel Sanz, Miguel
Article. 2014
PROGNOSTIC IMPACT OF TRANSPORTER GENE POLYMORPHISMS IN NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA ADULTS
Megias Vericat, J. E.; (...); Sanz, M. A.
Article. 2015
Prognostic significance of circulating tumor cells in advanced non-small cell lung cancer patients treated with docetaxel and gemcitabine
Juan O; (...); Gómez-Codina J
Article. 10.1007/s12094-013-1128-8. 2014
QUANTITATIVE APPROACH TO ASSIST NEUROBLASTOMA ASSESSMENT BY MEASURING I-123 mIBG UPTAKE IN SCINTIGRAPHIC IMAGES
Martinez-Diaz, Rafael; (...); Peris-Fajarnes, Guillermo
Article. 10.5566/ias.1219. 2015
Renal Transplantation Recipients with AA Genotype in SNP rs4244285 of CYP2C19 Show An Increase in Hospital Stay Duration and Allograft Dysfunction Probably Due to Increased Tacrolimus Levels Caused by Interaction with Omeprazol
Boso, V; (...); Alino, S. F.
Article. 10.1097/00007890-201211271-01757. 2012
Risk adapted high-dose and dose-dense therapies modulate the impact of biological classification in diffuse large B-cell lymphoma prognosis
Montes-Moreno, S; (...); Piris, M
Letter. 10.3324/haematol.2014.104976. 2014
Safety and efficacy of sorafenib in the treatment of advanced hepatocellular carcinoma: a single center experience
Imedio ER; (...); Salcedo JM
Article. 10.1007/s12032-014-0948-x. 2014
Selective ophthalmic intra-arterial melphalan therapy for advanced retinoblastoma: implementation and outcomes of a new chemotherapy protocol.
Valero García S; (...); Poveda Andrés JL
Article. 10.1177/1078155212457964. 2013
Single Nucleotide Polymorphisms, SNPs, Associated With the Efficacy and Security of Immunosuppressive Treatment in Heart Transplantation
Sanchez-Lazaro, I.; (...); Salvador-Sanz, A.
Article. 10.1016/j.healun.2014.01.392. 2014
SNPs and taxane toxicity in breast cancer patients
Bosó V; (...); Aliño SF
Article. 10.2217/PGS.14.127. 2014
Spanish Consensus on the Prevention and Treatment of Pseudomonas aeruginosa Bronchial Infections in Cystic Fibrosis Patients
Cantón R; (...); Solé A
Article. 10.1016/j.arbres.2014.09.021. 2015
STUDY OF THE CORRELATIONS BETWEEN SNPS IN ANGIOGENIC GENES AND TREATMENT RESPONSE/OUTCOME IN PATIENTS WITH ADVANCED NSCLC (NON-SQUAMOUS HISTOLOGY) TREATED IN FIRST LINE WITH CARBOPLATIN, PACLITAXEL AND BEVACIZUMAB (CPB). THE ANGIOMET STUDY.
Massuti, Bartomeu; (...); Camps, Carlos
Article. 2013
Study on the Linezolid Prescription According to the Approval of Indication in a University Hospital
Pérez-Cebrián M; (...); Llopis-González A
Article. 2015
Treatment adherence and other patient-reported outcomes as cost determinants in multiple sclerosis: a review of the literature
Lizan, L; (...); Polanco, C
Review. 10.2147/PPA.S67253. 2014
VEGF and TSP1 levels correlate with prognosis in advanced non-small cell lung cancer.
Fleitas T; (...); Reynés G
Article. 10.1007/s12094-013-1020-6. 2013