Búsqueda de marcadores metabolómicos de respuesta a la inmunoterapia y estudio del metabolismo de las células supresoras de origen mieloide como diana terapéutica en cáncer de pulmón.

Datos básicos

Código:
FPU18/02951
Protocolo:
FPU18/02951
EUDRACT:
NCT:
Centro:
Dotación:
172.330,00 €
Año de incio:
2019
Año de finalización:
2023
RRHH NACIONAL Finan. Competitiva Pública

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

MINISTERIO DE CIENCIA E INNOVACION

Resultados del Ensayo Clínico


A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway.

Ghergurovich JM; (...); Rabinowitz JD

Article. 10.1038/s41589-020-0533-x. 2020


Baseline circulating myeloid-derived suppressor cells correlate with neutrophil-to-lymphocyte ratio and overall survival in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors

Garcia-Sanchez, J.; (...); Lahoz, A.

Meeting Abstract. 2021


Baseline circulating myeloid-derived suppressor cells subpopulations, neutrophils/lymphocytes ratio, and response to PD-1/PD-L1 inhibitor in non-small cell lung cancer patients.

SAnchez, JosE GarcIa; (...); Lahoz, Agustin

Meeting Abstract. 2020


Calorie restriction improves metabolic state independently of gut microbiome composition: a randomized dietary intervention trial.

Sowah, Solomon A.; (...); Zeller, Georg

Article. 10.1186/s13073-022-01030-0. 2022


c-MYC Triggers Lipid Remodelling During Early Somatic Cell Reprogramming to Pluripotency

Prieto, Javier; (...); Torres, Josema

Article. 10.1007/s12015-021-10239-2. 2021


Changes in lipid metabolism driven by steroid signalling modulate proteostasis in C. elegans.

Gomez-Escribano, Ana P.; (...); Vazquez-Manrique, Rafael P.

Article. 10.15252/embr.202255556. 2023


Endothelin-1-Mediated Drug Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma

Pulido, I; (...); Shimamura, T

Article. 10.1158/0008-5472.CAN-20-0141. 2020


FAMetA: a mass isotopologue-based tool for the comprehensive analysis of fatty acid metabolism.

Alcoriza-Balaguer MI; (...); Lahoz A

Article. 10.1093/bib/bbad064. 2023


Glutamine/glutamate metabolism rewiring in reprogrammed human hepatocyte-like cells

Ballester, M; (...); Bort, R

Article. 10.1038/s41598-019-54357-x. 2019


Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1

Villalba, Maria; (...); Calvo, Alfonso

Article. 10.1038/s41598-019-51066-3. 2019


LipidMS 3.0: an R-package and a web-based tool for LC-MS/MS data processing and lipid annotation.

Alcoriza-Balaguer MI; (...); Lahoz, Agustin

Article. 10.1093/bioinformatics/btac581. 2022


Methods for analysis of specific DNA methylation status.

Pajares MJ; (...); Sandoval J

Article. 10.1016/j.ymeth.2020.06.021. 2020


Mild Muscle Mitochondrial Fusion Distress Extends Drosophila Lifespan through an Early and Systemic Metabolome Reorganization.

Tapia A; (...); Galindo MI

Article. 10.3390/ijms222212133. 2021


Non-Invasive Infections Diagnosis in Lung Transplant Recipients in Exhaled Breath Condensate

Ibanez-Martinez, E.; (...); Sole-Jover, A.

Meeting Abstract. 2021


PLEIOTROPIC EFFECT OF MIR-146A CAUSES PLATELET HYPERREACTIVITY AND THROMBOSIS THROUGH METABOLIC ICA REPROGRAMMING

Sonia, Aguila; (...); Constantino, Martinez

Meeting Abstract. 2021

  • Open Access.

Pre-diagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma.

Stepien, Magdalena; (...); Jenab, Mazda

Article. 10.1002/ijc.33885. 2022


Reviewing the metabolome coverage provided by LC-MS: Focus on sample preparation and chromatography-A tutorial

Roca; (...); Lahoz

Review. 2021


Reviewing the metabolome coverage provided by LC-MS: Focus on sample preparation and chromatography-A tutorial.

Roca M; (...); Lahoz A

Article. 10.1016/j.aca.2020.12.025. 2021


Sex Differences in the Efficacy of Immune Checkpoint Inhibitors in Neoadjuvant Therapy of Non-Small Cell Lung Cancer: A Meta-Analysis

Suay, Guillermo; (...); Juan-Vidal, Oscar

Review. 10.3390/cancers15184433. 2023


Starkeya nomas sp. nov., a prosthecate and budding bacterium isolated from an immunocompromized patient.

Sahuquillo-Arce JM; (...); López-Hontangas JL

Article. 10.1099/ijsem.0.005805. 2023


The Potential Role of Efficacy and Safety Evaluation of N-Acetylcysteine Administration During Liver Procurement. The NAC-400 Single Center Randomized Controlled Trial

Gomez-Gavara, C; (...); Lopez-Andujar, R

Article. 10.1097/TP.0000000000003487. 2021


Translation of a tissue epigenetic signature to circulating free DNA suggests BCAT1 as a potential noninvasive diagnostic biomarker for lung cancer

Palanca-Ballester, Cora; (...); Sandoval, Juan

Article. 10.1186/s13148-022-01334-3. 2022


Tumor Microenvironment-Derived Metabolites: A Guide to Find New Metabolic Therapeutic Targets and Biomarkers

García-Cañaveras JC, Lahoz A

Review. 10.3390/cancers13133230. 2021


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