Portal de investigación
INTREALL HR 2010 ESTUDIO INTERNACIONAL PARA EL TRATAMIENTO DE LA LLA INFANTIL DE ALTO RIESGO 2010.
Datos básicos
- Protocolo:
- INTREALL-HR-2010
- EUDRACT:
- 2012-000810-12
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Año de incio:
- 2018
- Año de finalización:
- 2022
Objetivos del proyecto
Observaciones: Estado Comité: ACTIVO
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
A Randomized Comparison of Liposomal Daunorubicin/Daunorubicin Combined with Low-Dose Cytarabine and Etoposide or High-Dose Cytarabine and Fludarabine in Induction Treatment of Pediatric AML Using MRD- Based Risk Stratification in the NOPHO-DBH AML 2012 Protocol
De Moerloose, Barbara; (...); Abrahamsson, Jonas
Meeting Abstract. 10.1182/blood-2023-187251. 2023
Accurate donor and recipient selection and a short time to transplant offer excellent outcomes in upfront hematopoietic stem cell transplantation from matched unrelated donors for pediatric severe aplastic anemia and refractory cytopenia of childhood. A study of the Spanish Pediatric Group for Hematopoietic Cell Transplantation and Cell Therapy (GETH-TC).
Uria-Oficialdegui, M Luz; (...); Diaz-de-Heredia, Cristina
Letter. 10.1038/s41409-024-02406-z. 2024
ANALYSIS OF TREATMENT AND OUTCOME OF RELAPSED ACUTE LYMPHOBLASTIC LEUKEMIA ACCORDING TO IMMUNOPHENOTYPE IN SPAIN
Ramos Elbal, Eduardo; (...); Fuster, Jose Luis
Meeting Abstract. 2023
Atypical B-Cell Acute Lymphoblastic Leukemia with iAMP21 in the Context of Constitutional Ring Chromosome 21: A Case Report and Review of the Genetic Insights.
Gil, Jose Vicente; (...); Llop, Marta
Article. 10.3390/ijms26010357. 2025
Blinatumomab and inotuzumab for B cell precursor acute lymphoblastic leukaemia in children: a retrospective study from the Leukemia Working Group of the Spanish Society of Pediatric Hematology and Oncology (SEHOP)
Fuster, JL; (...); Ramirez, M
Article. 10.1111/bjh.16647. 2020
Blinatumomab to improve the outcome of children with relapsed B-cell acute lymphoblastic leukemia.
Fuster JL; (...); Dapena JL
Letter. 10.1007/s12094-021-02590-0. 2021
Bridges to pediatric stem cell transplant: a new lane through
Torres Guerola, Barbara, Carreno Sanchez, Sandra, Fernandez Navarro, Jose Maria
Meeting Abstract. 2018
Casuística de tumor miofibroblástico inflamatorio en centro terciario.
Martínez Navarro G; (...); Fernández Navarro JM
Case Reports. 10.1016/j.anpedi.2020.12.007. 2021
Casuistics of inflammatory myofibroblastic tumor in a tertiary center.
Martínez Navarro G; (...); Fernández Navarro JM
Case Reports. 10.1016/j.anpede.2020.12.016. 2021
CLINICAL EXPERIENCE IN THE USE OF MESENCHYMAL STROMAL CELLS IN PEDIATRIC GRAFT-VERSUS-HOST DISEASE: ON BEHALF OF THE SPANISH GROUP OF STEM CELL TRANSPLANTATION (GETH)
Echecopar Parente, Carlos; (...); Perez-Martinez, Antonio
Meeting Abstract. 2024
Comprehensive detection of CRLF2 alterations in acute lymphoblastic leukemia: a rapid and accurate novel approach.
Gil, Jose Vicente; (...); Barragan, Eva
Article. 10.3389/fmolb.2024.1362081. 2024
Characterization of Pediatric Acute Myeloid Leukemia With t(7;12)(q36;p13)
Ostlund, Anders; (...); Palmqvist, Lars
Article. 10.1002/gcc.70003. 2024
Chip-AML22 Master Protocol: An Open-Label Clinical Trial in Newly Diagnosed Pediatric De Novo Acute Myeloid Leukemia (AML) Patients Including a Linked Phase II Trial with Quizartinib in FLT3-ITD/ NPM1wt Patients - a Study By the NOPHO-DB-SHIP Consortium
Kaspers, Gertjan J. L.; (...); Pronk, Cornelis Jan
Meeting Abstract. 10.1182/blood-2023-181792. 2023
Defibrotide in Hematopoietic Stem Cell Transplant: An Study of Grupo Espanol De Trasplante Hematopoyetico (GETH) And Grupo Espanol De Trasplante De Medula En NinOS (GETMON)
Vicent, MG; (...); Diaz, MA
Meeting Abstract. 2020
Defibrotide In Hematopoietic Stem Cell Transplantation: A Multicenter Survey Study Of The Spanish Hematopoietic Stem Cell Transplantation Group (Geth).
González Vicent M; (...); Díaz MÁ
Article. 10.1111/ejh.13618. 2021
Development of Hepatoblastoma organoids as a patient-derived ex-vivo system
Zanatto, Laura; (...); Sancho-Bru, Pau
Meeting Abstract. 2022
ECLIM-SEHOP, a new platform to set up and develop international academic clinical trials for childhood cancer and blood disorders in Spain.
Bautista, F; (...); Sociedad Española de Hematología y Oncología Pediátrica (SEHOP)
Article. 10.1007/s12094-019-02221-9. 2019
ECLIM-SEHOP: how to develop a platform to conduct academic trials for childhood cancer.
Juan-Ribelles A; (...); Fernández-Teijeiro A
Article. 10.1007/s12094-024-03445-0. 2024
Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications
Carrillo-Reixach, J; (...); Armengol, C
Article. 10.1016/j.jhep.2020.03.025. 2020
Executive summary of clinical practice guideline for the management of invasive diseases caused by Aspergillus: 2018 Update by the GEMICOMED-SEIMC/REIPI.
Garcia-Vidal, C; (...); Cuenca-Estrella, M
Article. 10.1016/j.eimc.2018.03.018. 2019
Experience of the Spanish Group for Hematopoietic Transplantation (GETMON-GETH) in allogenic Hematopoietic stem cell Transplantation in Philadelphia acute lymphoblastic leukemia.
Galán Gómez V; (...); Pérez-Martínez A
Article. 10.1016/j.anpede.2021.02.016. 2022
Experiencia del Grupo Español de Trasplante Hematopoyético (GETMON-GETH) en el trasplante alogénico de progenitores hematopoyéticos en leucemia aguda linfoblástica Philadelphia.
Galán Gómez V; (...); Pérez-Martínez A
Article. 10.1016/j.anpedi.2021.02.015. 2021
Germline Predisposition to Pediatric Cancer, from Next Generation Sequencing to Medical Care.
Gargallo P; (...); Cañete A
Article. 10.3390/cancers13215339. 2021
Haploidentical transplantation in high-risk pediatric leukemia: A retrospective comparative analysis on behalf of the Spanish working Group for bone marrow transplantation in children (GETMON) and the Spanish Grupo for hematopoietic transplantation (GETH).
Pérez-Martínez A; (...); Díaz MÁ
Article. 10.1002/ajh.25661. 2020
Haploidentical versus Cord Blood transplantation in pediatric AML. A retrospective outcome analysis on behalf of the pediatric subcommittee of GETH (Grupo Español de Trasplante Hematopoyético).
Sisinni L; (...); de Heredia CD
Article. 10.1016/j.jtct.2024.07.013. 2024
Haploidentical vs. HLA-matched donor hematopoietic stem-cell transplantation for pediatric patients with acute lymphoblastic leukemia in second remission: A collaborative retrospective study of the Spanish Group for Bone Marrow Transplantation in Children (GETMON/GETH) and the Spanish Childhood Relapsed ALL Board (ReALLNet).
Moreno, Celia; (...); Fuster, Jose Luis
Article. 10.3389/fped.2023.1140637. 2023
Helpful Criteria When Implementing NGS Panels in Childhood Lymphoblastic Leukemia.
Vega-Garcia N; (...); Camós M
Article. 10.3390/jpm10040244. 2020
Hematopoietic stem cell transplantation in children with chronic granulomatous disease: the Spanish experience.
Alonso García L; (...); Diaz de Heredia Rubio C
Article. 10.3389/fimmu.2024.1307932. 2024
HLA-haploidentical transplantation in children: a retrospective analysis of the Spanish Working Party for Blood and Marrow Transplantation in Children (GETMON-GETH)
Pascual, A; (...); Diaz, MA
Meeting Abstract. 2018
Infectious Diseases Working Party Retrospective Study on HHV-6 encephalitis: clinical characteristics and outcome after allogeneic HSCT
Ward, KN; (...); Styczynski, J
Meeting Abstract. 2018
Liquid Biopsy Micro-RNA Profiling in Meduloblastoma
Yanez, Y; (...); Canete, A
Meeting Abstract. 2018
Management of Hyperleukocytosis in Pediatric Acute Myeloid Leukemia Using Immediate Chemotherapy without Leukapheresis, in Protocol NOPHO-DBH AML-2012
Zeller, Bernward; (...); Abrahamsson, Jonas
Meeting Abstract. 10.1182/blood-2023-184921. 2023
Management of hyperleukocytosis in pediatric acute myeloid leukemia using immediate chemotherapy without leukapheresis: results from the NOPHO-DBH AML 2012 Protocol.
Zeller B; (...); Abrahamsson J
Article. 10.3324/haematol.2024.285285. 2024
Measurable Residual Disease and Fusion Partner Independently Predict Survival and Relapse Risk in Childhood KMT2A-Rearranged Acute Myeloid Leukemia: A Study by the International Berlin-Frankfurt-Münster Study Group.
van Weelderen, Romy E; (...); Kaspers GJL
Article. 10.1200/JCO.22.02120. 2023
Measurable Residual Disease Assessed by Flow-Cytometry Is a Stable Prognostic Factor for Pediatric T-Cell Acute Lymphoblastic Leukemia in Consecutive SEHOP Protocols Whereas the Impact of Oncogenetics Depends on Treatment.
Vega-García N; (...); Camós M
Article. 10.3389/fped.2020.614521. 2021
Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease.
Tierens, Anne; (...); Abrahamsson, Jonas
Article. 10.1200/JCO.23.01841. 2024
Optimized Cytogenetic Risk-Group Stratification of KMT2A-Rearranged Pediatric Acute Myeloid Leukemia.
van Weelderen, Romy E.; (...); Kaspers, Gertjan J. L.
Article. 10.1182/bloodadvances.2023011771. 2024
Outcome after HSCT in Children with JMML from a Historical Point of View
Duarte, ML; (...); Vazquez, GP
Meeting Abstract. 2020
Outcomes of Unmanipulated Haploidentical Transplantation Using Post-Transplant Cyclophosphamide (PT-Cy) in Pediatric Patients With Acute Lymphoblastic Leukemia
Ruggeri, A; (...); Corbacioglu, S
Article. 10.1016/j.jtct.2021.01.016. 2021
POST-TRANSPLANT RELAPSE IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA IN THE ERA OF CAR-T CELL THERAPY. A MULTICENTER ANALYSIS OF GRUPO ESPANOL DE TRASPLANTE HEMATOPOYETICO Y TERAPIA CELULAR (GETHTC) PEDIATRIC COMMITTEE
Vicent, Marta Gonzalez; (...); de Heredia, Cristina Diaz
Meeting Abstract. https://doi.org/10.1016/j.jcyt.2024.11.016. 2024
Post-transplant relapse in pediatric acute lymphoblastic leukemia in the era of CAR-T cell therapy. A multicenter analysis of Grupo Espanol de Trasplante Hematopoyetico y Terapia Celular (GETH-TC) Pediatric Committee.
Gonzalez Vicent, M; (...); Diaz de Heredia, C
Article. 10.1016/j.jcyt.2024.11.016. 2024
Progressively transformed germinal center (PTGC): a challenging diagnosis. Four new pediatric cases
Andres, MM; (...); Fernandez, JM
Meeting Abstract. 2018
Review: Ewing Sarcoma Predisposition.
Gargallo P; (...); Cañete A
Article. 10.1007/s12253-019-00765-3. 2019
The International Network for Evaluating Outcomes (iNeo) of neonates: evolution, progress and opportunities
Shah, Prakesh S.; (...); Int Network Evaluating Outcomes iN
Review. 10.21037/tp.2019.07.06. 2019
Treosulfan-Based Conditioning Regimen In Pediatric Hematopoietic Stem Cell Transplantation: A Retrospective Analysis on Behalf of the Spanish Group for Hematopoietic Transplantation and Cellular Therapy (GETH-TC).
Galán V; (...); Pérez-Martínez A
Article. 10.1016/j.jtct.2023.08.016. 2023
UNRELATED DONOR TRANSPLANTATION OFFERS A REAL CURATIVE OPPORTUNITY FOR PATIENTS WITH TRANSFUSIONDEPENDENT THALASSAEMIA. EXPERIENCE OF THE SPANISH GROUP FOR BONE MARROW TRANSPLANTATION IN CHILDREN (GETH-TC)
Benitez Carabante, Maria Isabel; (...); de Heredia Rubio, Cristina Diaz
Meeting Abstract. 2024
UPFRONT MATCHED UNRELATED DONOR HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR SEVERE IDIOPATHIC APLASTIC ANEMIA AND REFRACTORY CYTOPENIA OF CHILDHOOD IN PEDIATRIC PATIENTS. SPANISH EXPERIENCE
Uria-Oficialdegui, M. Luz; (...); Diaz-de-Heredia, Crsitina
Meeting Abstract. 2024
Use of Eculizumab in Pediatric Patients with High-Risk Transplantation-Associated Thrombotic Microangiopathy: Outcomes and Risk Factors Associated with Response and Survival. A Retrospective Study on Behalf of the Spanish Group for Hematopoietic Transplantation and Cellular Therapy (GETH-TC).
Benítez Carabante MI; (...); Diaz-de-Heredia C
Article. 10.1016/j.jtct.2024.03.019. 2024