Portal de investigación
EVALUACIÓN DE LA EFICACIA Y SEGURIDAD DE TOLVAPTAN EN EL PACIENTE CRÍTICO.
Datos básicos
- Código:
- PGR-TOV-2018-01
- Protocolo:
- PGR-TOV-2018-01
- EUDRACT:
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Dotación:
- Año de incio:
- Año de finalización:
- 2017
Objetivos del proyecto
Observaciones: Estado Comité: APROBADO CEIm
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
[Management of infectious complications associated with coronavirus infection in severe patients admitted to ICU].
Estella, Angel; (...); Zaragoza, Rafael
Article. 10.1016/j.medin.2021.04.007. 2021
[Recommendations for the management of critically ill patients with COVID-19 in Intensive Care Units].
Vidal-Cortes, Pablo; (...); Crespo, Rafael Zaragoza
Article. 10.1016/j.medin.2021.08.011. 2021
Acceptance and validity of the methods used to implement a competency based medical education programme in an Intensive Care Department of a teaching referral center.
Castellanos-Ortega, A.; (...); Garcia-Ros, R.
Article. 10.1016/j.medin.2019.12.007. 2021
Acceptance and validity of the methods used to implement a competency based medical education programme in an Intensive Care Department of a teaching referral center.
Castellanos-Ortega A; (...); García-Ros R
Article. 10.1016/j.medine.2019.12.011. 2021
Acute coronary syndrome due to a giant right coronary artery aneurysm
Villarreal, E, Jannone, R, Castellanos, A
Editorial Material. 10.1016/j.medin.2016.09.002. 2018
Acute respiratory distress syndrome due to COVID-19. Clinical and prognostic features from a medical Critical Care Unit in Valencia, Spain.
Ramírez P; (...); Castellanos Á
Article. 10.1016/j.medin.2020.06.015. 2021
An outbreak due to Candida auris with prolonged colonisation and candidaemia in a tertiary care European hospital
Ruiz-Gaitan, A; (...); Peman, J
Article. 10.1111/myc.12781. 2018
Anti-endotoxin antibodies consumption in cardiovascular collapse: Pathophysiological concerns.
Villarreal, E.; (...); Vila, J.
Article. 10.1016/j.medine.2022.04.019. 2022
Antimicrobial Pharmacokinetics and Pharmacodynamics in Critical Care: Adjusting the Dose in Extracorporeal Circulation and to Prevent the Genesis of Multiresistant Bacteria.
Ruiz-Ramos, Jesus, Gras-Martin, Laura, Ramirez, Paula
Article. 10.3390/antibiotics12030475. 2023
Antimicrobial stewardship in hospitals: Expert recommendation guidance document for activities in specific populations, syndromes and other aspects (PROA-2) from SEIMC, SEFH, SEMPSPGS, SEMICYUC and SEIP.
Cercenado, Emilia; (...); Retamar-Gentil, Pilar
Practice Guideline. 10.1016/j.eimce.2022.05.013. 2023
Antimicrobial stewardship in hospitals: Expert recommendation guidance document for activities in specific populations, syndromes and other aspects (PROA-2) from SEIMC, SEFH, SEMPSPGS, SEMICYUC and SEIP
Cercenado, Emilia; (...); Retamar-Gentil, Pilar
Editorial Material. 10.1016/j.eimc.2022.05.005. 2023
Antimicrobial stewardship programme implementation in a medical ward
Ruiz, J; (...); Poveda, JL
Article. 2018
Antimicrobial stewardship programme in critical care medicine: A prospective interventional study
Ruiz, J; (...); Catellanos, A
Article. 10.1016/j.medin.2017.07.002. 2018
Antimicrobial stewardship programs in the intensive care unit in patients with infections caused by multidrug-resistant gram-negative bacilli
Ramos, J. Ruiz, Galleymore, P. Ramirez
Article. 10.1016/j.medin.2022.07.007. 2023
Antimicrobial stewardship programs in the Intensive Care Unit in patients with infections caused by multidrug-resistant Gram-negative bacilli.
Ruiz-Ramos J, Ramírez P
Article. 10.1016/j.medine.2022.09.004. 2022
Antisepsis for blood culture extraction. Blood culture contamination rate
Galleymore, PR, Sahuquillo, MG
Article. 10.1016/j.medin.2018.08.007. 2019
Beyond the Pandemic: The Value of Antimicrobial Stewardship
Kanj, Souha S., Ramirez, Paula, Rodrigues, Camilla
Article. 10.3389/fpubh.2022.902835. 2022
Biomarkers in pulmonary infections: a clinical approach.
Povoa, Pedro; (...); Kalil, Andre C
Article. 10.1186/s13613-024-01323-0. 2024
Biomarkers in the ICU: less is more? Yes.
Huang, David T., Ramirez, Paula
Editorial Material. 10.1007/s00134-020-06049-8. 2021
Cefiderocol pharmacokinetics in critically ill patients undergoing ECMO support.
Marín-Cerezuela M; (...); Ramirez P
Letter. 10.1186/s13054-024-05126-4. 2024
Ceftaroline versus standard therapy for pneumococcal meningitis in critically ill patients.
Martin-Cerezuela, M; (...); Galleymore, P R
Article. 10.1016/j.medin.2021.05.011. 2021
Ceftaroline versus standard therapy for pneumococcal meningitis in critically ill patients.
Martín-Cerezuela M; (...); Galleymore PR
Article. 10.1016/j.medine.2021.05.007. 2022
Ceftolozane/Tazobactam Dosing Requirements Against Pseudomonas aeruginosa Bacteremia.
Ruiz J; (...); Ramirez P
Article. 10.1177/1559325819885790. 2020
Clinical characteristics, evolution, and treatment-related risk factors for mortality among immunosuppressed patients with influenza A (H1N1) virus admitted to the intensive care unit
Garnacho-Montero, J; (...); GETGAG Study Grp
Article. 10.1016/j.jcrc.2018.08.017. 2018
Clinical characteristics, risk factors and management of patients with inflammatory bowel disease and hidradenitis suppurativa: a nationwide multicenter study of the GETECCU ENEIDA registry
Madero Velazquez, L.; (...); Gutierrez-Casbas, A.
Meeting Abstract. 2024
Colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia (Magic Bullet study): an investigator-driven, open-label, randomized, noninferiority controlled trial
Cisneros, JM; (...); Magic Bullet Working Grp WP1
Article. 10.1186/s13054-019-2627-y. 2019
Current aspects in sepsis approach. Turning things around
Javier Candel, Francisco; (...); Vidal, Pablo
Review. 2018
Current Positioning against Severe Infections Due to Klebsiella pneumoniae in Hospitalized Adults.
Vidal-Cortes, Pablo; (...); Zaragoza, Rafael
Review. 10.3390/antibiotics11091160. 2022
Decolonization strategies against multidrug resistant organisms in the ICU.
Póvoa P, Ramirez P, Blot S
Editorial Material. 10.1007/s00134-024-07360-4. 2024
Decontamination Strategies and Bloodstream Infections With Antibiotic-Resistant Microorganisms in Ventilated Patients A Randomized Clinical Trial
Wittekamp, BH; (...); Bonten, MJM
Article. 10.1001/jama.2018.13765. 2018
Design of a new mortality indicator in acute coronary syndrome on admission to the Intensive Care Unit.
Lozano Gomez, Herminia; (...); Araiz Burdio, Juan Jose
Article. 10.1016/j.medine.2023.03.008. 2023
Design of a new mortality indicator in acute coronary syndrome on admission to the Intensive Care Unit
Gomez, Herminia Lozano; (...); Araiz Burdio, Juan Jose
Article. 10.1016/j.medin.2023.02.002. 2023
Detection and treatment of Candida auris in an outbreak situation: risk factors for developing colonization and candidemia by this new species in critically ill patients
Ruiz-Gaitan, Alba; (...); Peman, Javier
Article. 10.1080/14787210.2019.1592675. 2019
Determination of meropenem in endotracheal tubes by in-tube solid phase microextraction coupled to capillary liquid chromatography with diode array detection
Hakobyan, L; (...); Campins-Falco, P
Article. 10.1016/j.jpba.2018.01.006. 2018
Effect of pharmacokinetic/pharmacodynamic ratio on tigecycline clinical response and toxicity in critically ill patients with multidrug-resistant Gram-negative infections
Ruiz, J; (...); Castellanos-Ortega, A
Article. 10.1177/2050312120958897. 2020
Efficacy and Experience of Bacteriophages in Biofilm-Related Infections.
Gordon, Monica, Ramirez, Paula
Article. 10.3390/antibiotics13020125. 2024
Evaluation of the Kinetics of Pancreatic Stone Protein as a Predictor of Ventilator-Associated Pneumonia.
Ceccato, Adrian; (...); Artigas, Antonio
Article. 10.3390/biomedicines11102676. 2023
Executive summary: Diagnosis and Treatment of Catheter-Related Bloodstream Infection: Clinical Guidelines of the Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC) and the Spanish Society of Intensive Care Medicine and Coronary Units (SEMICYUC)
Chaves, F; (...); Valles, J
Article. 10.1016/j.eimc.2017.10.019. 2018
Fosfomycin in infections caused by multidrug-resistant Gram-negative pathogens.
Ruiz Ramos J, Salavert Lletí M
Article. 2019
Four cases of unexpected severe community-acquired pneumonia aetiology: Group A Streptococcus pyogenes disruption
Talavera, Monica; (...); Ramirez, Paula
Letter. 10.1016/j.medin.2023.04.013. 2023
Four cases of unexpected severe community-acquired pneumonia aetiology: Group A Streptococcus pyogenes disruption.
Talavera, Monica; (...); Ramirez, Paula
Case Reports. 10.1016/j.medine.2023.05.004. 2023
Fungal co-infection in COVID-19 patients: Should we be concerned?
Pemán J; (...); Quindós G
Review. 10.1016/j.riam.2020.07.001. 2020
How to use biomarkers of infection or sepsis at the bedside: guide to clinicians.
Povoa, Pedro; (...); Kalil, Andre C.
Article. 10.1007/s00134-022-06956-y. 2023
Impact of amikacin pharmacokinetic/pharmacodynamic index on treatment response in critically ill patients
Ruiz, J; (...); Castellanos-Ortega, A
Article. 10.1016/j.jgar.2017.09.019. 2018
Impact of the "Zero Resistance" program on acquisition of multidrug-resistant bacteria in patients admitted to Intensive Care Units in Spain. A prospective, intervention, multimodal, multicenter study.
Álvarez-Lerma F; (...); Martínez-Alonso M
Article. 10.1016/j.medine.2022.12.002. 2023
Impact of the ?Zero Resistance? program on acquisition of multidrug-resistant bacteria in patients admitted to Intensive Care Units in Spain. A prospective, intervention, multimodal, multicenter study
Alvarez-Lerma, Francisco; (...); Martinez-Alonso, Montserrat
Article. 10.1016/j.medin.2022.12.002. 2023
Impact of voriconazole plasma concentrations on treatment response in critically ill patients
Ruiz, J; (...); Ramirez, P
Article. 10.1111/jcpt.12817. 2019
In vitro study of antimicrobial activity on Klebsiella Pneumoniae biofilms in endotracheal tubes
Ruiz, J; (...); Ramirez, P
Article. 10.1080/1120009X.2019.1601801. 2019
Individualised antimicrobial dosing in critically ill patients undergoing continuous renal replacement therapy: focus on total drug clearance
Ruiz, J; (...); Ramirez, P
Article. 10.1136/ejhpharm-2016-001114. 2018
Influence of antibiotic pressure on multi-drug resistant Klebsiella pneumoniae colonisation in critically ill patients
Ruiz, J; (...); Ramirez, P
Article. 10.1186/s13756-019-0484-8. 2019
Influence of pharmacokinetic/pharmacodynamic ratio on vancomycin treatment response in paediatric patients with Staphylococcus aureus bacteremia.
Ruiz J; (...); Poveda JL
Article. 10.23736/S0026-4946.18.04978-2. 2018
Initial Antifungal Strategy Reduces Mortality in Critically Ill Patients With Candidemia: A Propensity Score-Adjusted Analysis of a Multicenter Study*
Garnacho-Montero, J; (...); Garcia-Garmendia, JL
Article. 10.1097/CCM.0000000000002867. 2018
Invasive aspergillosis in critically ill patients
Ramirez, P, Garnacho-Montero, J
Review. 10.1016/j.riam.2018.07.001. 2018
Lymphopenic community-acquired pneumonia is associated with a dysregulated immune response and increased severity and mortality
Mendez, R; (...); Torres, A
Article. 10.1016/j.jinf.2019.04.006. 2019
Management of infectious complications associated with coronavirus infection in severe patients admitted to ICU.
Estella, A; (...); Zaragoza, R
Article. 10.1016/j.medine.2021.08.013. 2021
MINIMALLY INVASIVE VERSUS OPEN HYSTERECTOMY IN HIGH-RISK ENDOMETRIAL CANCER: A PROPENSITY SCORE MATCHING ANALYSIS
Segarra Vidal, B.; (...); Ramirez, P.
Meeting Abstract. 10.1136/ijgc-2021-ESGO.206. 2021
Monographic: antisepsis in the critical patient Introduction
Ramirez, P., Nuvials, X., Diaz, E.
Editorial Material. 10.1016/j.medin.2018.07.018. 2019
New evidence in severe pneumonia: meropenem-vaborbactam.
Forteza Guillot, Maria, Martin Cerezuela, Maria, Ramirez, Paula
Article. 10.37201/req/s01.10.2022. 2022
Outbreak of Candida auris in Spain: A comparison of antifungal activity by three methods with published data
Ruiz-Gaitan, AC; (...); Peman, Javier
Article. 10.1016/j.ijantimicag.2019.02.005. 2019
OUTCOMES FOLLOWING OPEN RADICAL HYSTERECTOMY AFTER IMPLEMENTATION OF AN ENHANCED RECOVERY AFTER SURGERY (ERAS) PROGRAM
Agusti, N.; (...); Ramirez, P.
Meeting Abstract. 10.1136/ijgc-2021-ESGO.67. 2021
Practical document on the management of hyponatremia in critically ill patients
Porcar, MJB; (...); Herrera-Gutierrez, ME
Article. 10.1016/j.medin.2018.12.002. 2019
Recomendaciones GEMICOMED/GEIRAS-SEIMC para el manejo de las infecciones y colonizaciones por Candida auris.
Alastruey-Izquierdo A; (...); en nombre de GEMICOMED GEIRAS-SEIMC
Abstract of Published Item. 10.1016/j.riam.2019.06.001. 2019
Recommendations for the management of critically ill patients with COVID-19 in Intensive Care Units.
Vidal-Cortés P; (...); Zaragoza Crespo R
Practice Guideline. 10.1016/j.medine.2021.11.019. 2022
Reply to: "ormothermic regional perfusion - What is the benefit?''
Hessheimer, AJ; (...); Fondevila, C
Letter. 10.1016/j.jhep.2019.04.005. 2019
Risk of immunomediated adverse events or secondary loss of response to infliximab in elderly patients with inflammatory bowel disease: a cohort study of the ENEIDA registry
Calafat, M; (...); Domenech, E
Meeting Abstract. 10.1093/ecco-jcc/jjy222.561. 2019
Severe community-acquired Streptococcus pneumoniae bacterial meningitis: clinical and prognostic picture from the intensive care unit.
Martín-Cerezuela M; (...); Ramírez-Galleymore P
Article. 10.1186/s13054-023-04347-3. 2023
Soluble urokinase plasminogen activator receptor (suPAR) for the prediction of ventilator-associated pneumonia (VAP)
van Oort, PMP; (...); Martin-Loeches, I
Meeting Abstract. 10.1183/13993003.congress-2018.PA2607. 2018
Soluble urokinase plasminogen activator receptor for the prediction of ventilator-associated pneumonia.
van Oort PM; (...); Martin-Loeches I
Article. 10.1183/23120541.00212-2018. 2019
Ten Issues to Update in Nosocomial or Hospital-Acquired Pneumonia: An Expert Review.
Candel, Francisco Javier; (...); Zaragoza, Rafael
Article. 10.3390/jcm12206526. 2023
Textbook outcome in patients with biliary duct injury during cholecystectomy.
Lopez-Lopez V; (...); Robles-Campos R
Article. 10.1016/j.gassur.2024.02.027. 2024
The challenge of multiresistant microorganisms.
Vicent C, Ramírez P
Editorial Material. 10.1016/j.medcli.2023.12.004. 2024
The UK DCD Risk Score: Still no consensus on futility in DCD liver transplantation
Hessheimer, AJ; (...); Fondevila, C
Letter. 10.1016/j.jhep.2019.01.004. 2019
Transcriptomic depression of immunological synapse as a signature of ventilator-associated pneumonia
Almansa, R; (...); Martin-Loeches, I
Article. 10.21037/atm.2018.05.12. 2018
Transcriptomics reveals shared immunosuppressive landscapes in ventilator-associated lower respiratory tract infections (VA-LRTI) patients.
Martin-Loeches I; (...); Bermejo-Martín JF
Article. 10.1080/14787210.2023.2256979. 2023
Treatment of critically ill patients with cefiderocol for infections caused by multidrug-resistant pathogens: review of the evidence.
Viale, Pierluigi; (...); Lodise, Thomas P.
Article. 10.1186/s13613-023-01146-5. 2023
Update of the treatment of nosocomial pneumonia in the ICU
Zaragoza, R; (...); Martin-Loeches, I
Review. 10.1186/s13054-020-03091-2. 2020
Vancomycin and daptomycin minimum inhibitory concentrations as a predictor of outcome of methicillin-resistant Staphylococcus aureus bacteraemia
Ruiz, J; (...); Castellanos-Ortega, A
Article. 10.1016/j.jgar.2018.03.007. 2018
Vasopressin antagonist efficacy and safety in volume-overloaded critically ill patients: a new therapeutic alternative
Ruiz-Ramos, J; (...); Castellanos-Ortega, A
Article. 10.1136/ejhpharm-2018-001664. 2020