OPEN-LABEL, INDIVIDUAL DOSE TITRATION STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACOKINETICS OF RIOCIGUAT IN CHILDREN FROM 6 TO LESS THAN 18 YEARS OF AGE WITH PULMONARY ARTERIAL HYPERTENSION (PAH).
Datos básicos
- Código:
- BAY63-2521/15681
- Protocolo:
- BAY63-2521/15681
- EUDRACT:
- 2014-003952-29
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Dotación:
- Año de incio:
- 2017
- Año de finalización:
- 2020
Objetivos del proyecto
Observaciones: Estado Comité: ACTIVO
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
Aneurisma del ductus arterioso: diagnóstico prenatal y evolución.
ESTEBAN PEIRÓ MOLINA, ANTONIO SANCHEZ ANDRES, JOSÉ IGNACIO CARRASCO MORENO
Article. DOI: 10.1016/j.anpedi.2016.10.007. 2017
Cardiopulmonary Rehabilitation Improves Respiratory Muscle Function and Functional Capacity in Children with Congenital Heart Disease. A Prospective Cohort Study
Ferrer-Sargues FJ; (...); Iranzo, MACI
Article. 10.3390/ijerph17124328. 2020
Clinical Implications of the Genetic Background in Pediatric Pulmonary Arterial Hypertension: Data from the Spanish REHIPED Registry
Cruz-Utrilla, Alejandro; (...); Del Cerro Marin, Maria Jesus
Article. 10.3390/ijms231810433. 2022
Ductus arteriosus aneurysm: Prenatal diagnosis and outcome
Peiró Molina E, Sánchez Andrés A, Carrasco Moreno JI
Editorial Material. 10.1016/j.anpedi.2016.10.007. 2017
Effects of Cardiopulmonary Rehabilitation on the Muscle Function of Children with Congenital Heart Disease: A Prospective Cohort Study.
Ferrer-Sargues FJ; (...); Salvador-Coloma P
Article. 10.3390/ijerph18115870. 2021
Expanding the Evidence of a Semi-Dominant Inheritance in GDF2 Associated with Pulmonary Arterial Hypertension.
Gallego N; (...); Tenorio-Castaño J
Article. 10.3390/cells10113178. 2021
Expanding the evidence of a semi-dominant inheritancein GDF2 associated with Pulmonary Arterial Hypertension
Gallego, Natalia; (...); Tenorio, Jair
Meeting Abstract. 2024
Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction.
Amaro-Prellezo, Elena; (...); Sepulveda, Pilar
Article. 10.1186/s41232-024-00340-7. 2024
Extracellular Vesicles Secreted by Hypoxic AC10 Cardiomyocytes Modulate Fibroblast Cell Motility.
Ontoria-Oviedo, I; (...); Sepulveda, P
Article. 10.3389/fcvm.2018.00152. 2018
Kawasaki giant coronary aneurysms in infants with Kawasaki disease
Sánchez Andrés A, Carrasco Moreno JI
Letter. 10.1016/j.anpedi.2017.11.009. 2018
Long-term reoperation in Tetralogy of Fallot: is it possible to preserve the native pulmonary valve again?
Martineza, Felix Serrano; (...); Molinab, Esteban Peiro
Article. 10.1016/j.circv.2022.01.009. 2022
miR-4732-3p in Extracellular Vesicles From Mesenchymal Stromal Cells Is Cardioprotective During Myocardial Ischemia
Sánchez-Sánchez R; (...); Sepúlveda P
Article. 10.3389/fcell.2021.734143. 2021
Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs.
Reinal, Ignacio; (...); Sepulveda, Pilar
Article. 10.3390/antiox12071378. 2023
Percutaneous closure of ventricular septal defect with the KONAR-MF device
Alvarez-Fuente, Maria; (...); Del Cerro, Maria Jesus
Article. 10.24875/RECICE.M22000277. 2022
Preparo Mi Rotacin Por, complemento virtual de la formacin MIR en Pediatra.
Hijano Bandera F; (...); Coordinadores de Continuum
Abstract of Published Item. 10.1016/j.anpedi.2019.10.001. 2019
Pulmonary arterial hypertension in Spanish pediatric registry age: clinical characterization, management and survival
Escribano, JP; (...); REHIPED Investigators
Meeting Abstract. 2020
Seven Additional Patients with SOX17 Related Pulmonary Arterial Hypertension and Review of the Literature.
Gallego-Zazo, Natalia; (...); Tenorio-Castano, Jair
Article. 10.3390/genes14101965. 2023