OPEN-LABEL, INDIVIDUAL DOSE TITRATION STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACOKINETICS OF RIOCIGUAT IN CHILDREN FROM 6 TO LESS THAN 18 YEARS OF AGE WITH PULMONARY ARTERIAL HYPERTENSION (PAH).

Datos básicos

Código:
BAY63-2521/15681
Protocolo:
BAY63-2521/15681
EUDRACT:
2014-003952-29
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Dotación:
Año de incio:
2017
Año de finalización:
2020
ENSAYO CLÍNICO INTERNACIONAL

Objetivos del proyecto

Observaciones: Estado Comité: ACTIVO

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

BAYER HEALTHCARE
BAYER HEALTHCARE AG

Resultados del Ensayo Clínico


Aneurisma del ductus arterioso: diagnóstico prenatal y evolución.

ESTEBAN PEIRÓ MOLINA, ANTONIO SANCHEZ ANDRES, JOSÉ IGNACIO CARRASCO MORENO

Article. DOI: 10.1016/j.anpedi.2016.10.007. 2017


Cardiopulmonary Rehabilitation Improves Respiratory Muscle Function and Functional Capacity in Children with Congenital Heart Disease. A Prospective Cohort Study

Ferrer-Sargues FJ; (...); Iranzo, MACI

Article. 10.3390/ijerph17124328. 2020


Clinical Implications of the Genetic Background in Pediatric Pulmonary Arterial Hypertension: Data from the Spanish REHIPED Registry

Cruz-Utrilla, Alejandro; (...); Del Cerro Marin, Maria Jesus

Article. 10.3390/ijms231810433. 2022


Ductus arteriosus aneurysm: Prenatal diagnosis and outcome

Peiró Molina E, Sánchez Andrés A, Carrasco Moreno JI

Editorial Material. 10.1016/j.anpedi.2016.10.007. 2017


Effects of Cardiopulmonary Rehabilitation on the Muscle Function of Children with Congenital Heart Disease: A Prospective Cohort Study.

Ferrer-Sargues FJ; (...); Salvador-Coloma P

Article. 10.3390/ijerph18115870. 2021


Expanding the Evidence of a Semi-Dominant Inheritance in GDF2 Associated with Pulmonary Arterial Hypertension.

Gallego N; (...); Tenorio-Castaño J

Article. 10.3390/cells10113178. 2021


Expanding the evidence of a semi-dominant inheritancein GDF2 associated with Pulmonary Arterial Hypertension

Gallego, Natalia; (...); Tenorio, Jair

Meeting Abstract. 2024

  • Open Access.

Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction.

Amaro-Prellezo, Elena; (...); Sepulveda, Pilar

Article. 10.1186/s41232-024-00340-7. 2024


Extracellular Vesicles Secreted by Hypoxic AC10 Cardiomyocytes Modulate Fibroblast Cell Motility.

Ontoria-Oviedo, I; (...); Sepulveda, P

Article. 10.3389/fcvm.2018.00152. 2018


Kawasaki giant coronary aneurysms in infants with Kawasaki disease

Sánchez Andrés A, Carrasco Moreno JI

Letter. 10.1016/j.anpedi.2017.11.009. 2018


Long-term reoperation in Tetralogy of Fallot: is it possible to preserve the native pulmonary valve again?

Martineza, Felix Serrano; (...); Molinab, Esteban Peiro

Article. 10.1016/j.circv.2022.01.009. 2022


miR-4732-3p in Extracellular Vesicles From Mesenchymal Stromal Cells Is Cardioprotective During Myocardial Ischemia

Sánchez-Sánchez R; (...); Sepúlveda P

Article. 10.3389/fcell.2021.734143. 2021


Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs.

Reinal, Ignacio; (...); Sepulveda, Pilar

Article. 10.3390/antiox12071378. 2023


Percutaneous closure of ventricular septal defect with the KONAR-MF device

Alvarez-Fuente, Maria; (...); Del Cerro, Maria Jesus

Article. 10.24875/RECICE.M22000277. 2022


Preparo Mi Rotacin Por, complemento virtual de la formacin MIR en Pediatra.

Hijano Bandera F; (...); Coordinadores de Continuum

Abstract of Published Item. 10.1016/j.anpedi.2019.10.001. 2019


Pulmonary arterial hypertension in Spanish pediatric registry age: clinical characterization, management and survival

Escribano, JP; (...); REHIPED Investigators

Meeting Abstract. 2020


Seven Additional Patients with SOX17 Related Pulmonary Arterial Hypertension and Review of the Literature.

Gallego-Zazo, Natalia; (...); Tenorio-Castano, Jair

Article. 10.3390/genes14101965. 2023


Campos de estudio

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