ENSAYO CLÍNICO FASE IB/II DE NIVOLUMAB EN MONOTERAPIA Y NIVOLUMAB EN COMBINACIÓN CON IPILIMUMAB EN PACIENTES PEDIÁTRICOS CON NEOPLASIAS MALIGNAS PRIMARIAS DEL SNC DE ALTO GRADO.

Datos básicos

Protocolo:
CA209-908
EUDRACT:
2016-004441-82
NCT:
Centro:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Año de incio:
2017
Año de finalización:
2021
ENSAYO CLÍNICO INTERNACIONAL

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

BRISTOL-MYERS SQUIBB SAU

Resultados del Ensayo Clínico


1p36 deletion results in a decrease in glycosaminoglycans which is associated with aggressiveness in neuroblastic tumors

Tadeo, I; (...); Noguera, R

Article. 10.1467/HH-11-947. 2018


A Confidence Habitats Methodology in MR Quantitative Diffusion for the Classification of Neuroblastic Tumors.

Cerda Alberich, Leonor; (...); Marti-Bonmati, Luis

Article. 10.3390/cancers12123858. 2020

  • Open Access.

A NATIONAL PEDIATRIC NEURO-ONCOLOGY TUMOR BOARD INITIATIVE IN SPAIN: RESULTS OF A WEB-BASED SURVEY TO EVALUATE PARTICIPANT EXPERIENCE UTILIZING THIS RESOURCE

Illade, Laura; (...); Lassaletta, Alvaro

Article. 2022


A randomized, open-label, phase 2 study evaluating abemaciclib in combination with irinotecan and temozolomide in participants with relapsed or refractory Ewing sarcoma

Van Hal, Gertjan; (...); Lewin, Jeremy Howard

Meeting Abstract. 2023


Adolescent cancer care: What has changed in Spain in the past decade?

Garrido Colino, Carmen; (...); Vagace Valero, Jose Manuel

Article. 10.1016/j.anpede.2023.01.003. 2023


Adolescent cancer care: What has changed in Spain in the past decade?

Garrido Colino, Carmen; (...); SEHOP

Article. 10.1016/j.anpedi.2022.09.012. 2023

  • Open Access.

Alectinib in pediatric patients with solid or CNS tumors harboring ALK-fusions: Emerging pharmacokinetic data from the iMATRIX alectinib phase I/II open-label, multi-center study

Doz, Francois; (...); Gajjar, Amar J.

Meeting Abstract. https://doi.org/10.1200/JCO.2024.42.16_suppl.3098. 2024

  • Open Access.

ASSESSMENT OF A NOVEL READY-TO-USE TEMOZOLOMIDE ORAL SUSPENSION IN CHILDREN WITH SOLID TUMORS: RESULTS OF TEMOKIDS, A POPULATION PHARMACOKINETIC, ACCEPTABILITY AND SAFETY PHASE-1 STUDY

Abbou, Samuel; (...); Metayer, Lucy

Meeting Abstract. 2023


Assessment of the dicentric chromosome assay as a biodosimetry tool for more personalized medicine in a case of a high risk neuroblastoma I-131-mIBG treatment

Chimeno, JM; (...); Montoro, A

Article. 10.1080/09553002.2019.1549755. 2018


Barriers and facilitators to implementation of the interoperable Survivorship Passport (SurPass) v2.0 in 6 European countries: a PanCareSurPass online survey study.

van den Oever, Selina R; (...); Pluijm, Saskia M F

Article. 10.1007/s11764-023-01335-y. 2023

  • Open Access.

Barriers and facilitators to the implementation of a new European eHealth solution (SurPass v2.0): the PanCareSurPass Open Space study.

de Beijer IAE; (...); Pluijm SMF

Article. 10.1007/s11764-023-01498-8. 2023

  • Open Access.

Bridges to pediatric stem cell transplant: a new lane through

Torres Guerola, Barbara, Carreno Sanchez, Sandra, Fernandez Navarro, Jose Maria

Meeting Abstract. 2018


Cadmium (Cd) and Lead (Pb) topsoil levels and incidence of childhood leukemias

Asenjo S; (...); Ramis R

Article. 10.1007/s10653-021-01030-w. 2021


Can We Identify Chemotherapy-Related Toxicity in Children with Cancer Through Automatized Integration of Healthcare Information Systems?

Berlanga, P; (...); Canete, A

Meeting Abstract. 2017


Cáncer en los primeros 18 meses de vida.

Urtasun Erburu A, Herrero Cervera MJ, Cañete Nieto A

Article. 10.1016/j.anpedi.2020.02.015. 2020

  • Open Access.

Cancer is not a risk factor for severe COVID-19 in children, except in patients with recent allogeneic hematopoietic stem cell transplantation or comorbidities.

Velasco Puyó P; (...); Astigarraga I

Article. 10.1002/pbc.31120. 2024


Casuística de tumor miofibroblástico inflamatorio en centro terciario.

Martínez Navarro G; (...); Fernández Navarro JM

Case Reports. 10.1016/j.anpedi.2020.12.007. 2021

  • Open Access.

Casuistics of inflammatory myofibroblastic tumor in a tertiary center.

Martínez Navarro G; (...); Fernández Navarro JM

Case Reports. 10.1016/j.anpede.2020.12.016. 2021

  • Open Access.

Central nervous system relapse in high-risk stage 4 neuroblastoma: The HR-NBL1/SIOPEN trial experience

Berlanga, P; (...); Ladenstein, R

Article. 10.1016/j.ejca.2020.10.020. 2021

  • Open Access.

Clinical experience of whole body and tumour dosimetry of 131-I-mIBG treatment for pediatric patients

Espallardo, I. Torres; (...); Prado-Wohlwend, S.

Meeting Abstract. 2023


Clinical Features of Neuroblastoma With 11q Deletion: An Increase in Relapse Probabilities In Localized And 4S Stages.

J Ribelles A; (...); Castel V

Article. 10.1038/s41598-019-50327-5. 2019

  • Open Access.

Cmo tratamos el hemangioendotelioma kaposiforme?

Huerta-Calpe S; (...); Pérez-Tarazona S

Article. 10.1016/j.anpedi.2018.09.002. 2019

  • Open Access.

COMBINED RADIOLOGICAL, PATHOLOGICAL AND MOLECULAR OUTCOME EVALUATION IN NEWLY DIAGNOSED NON-BRAINSTEM PEDIATRIC HIGH-GRADE GLIOMA FROM THE RANDOMIZED, MULTICENTER HERBY PHASE II TRIAL

Jaspan, T; (...); Grill, J

Meeting Abstract. 2018


Comparative Multicentric Evaluation of Inter-Observer Variability in Manual and Automatic Segmentation of Neuroblastic Tumors in Magnetic Resonance Images

Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis

Article. 10.3390/cancers14153648. 2022

  • Open Access.

Comprehensive evaluation of context dependence of the prognostic impact of MYCN amplification in neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project

Campbell, K; (...); DuBois, SG

Article. 10.1002/pbc.27819. 2019

  • Open Access.

Congenital Critical Heart Defect Screening in a Health Area of the Community of Valencia (Spain): A Prospective Observational Study

Cubells, E; (...); Vento, M

Article. 10.3390/ijns4010003. 2018

  • Open Access.

Consensus SEO-SEFH of recommendations for use and compounding of ophthalmic preparations.

Fuentes-Irigoyen, R; (...); Yañez Martínez JR

Article. 10.7399/fh.10943. 2018

  • Open Access.

Correction: Barriers and facilitators to the implementation of a new European eHealth solution (SurPass v2.0): the PanCareSurPass Open Space study.

de Beijer IAE; (...); Pluijm SMF

Correction. 10.1007/s11764-024-01547-w. 2024

  • Open Access.

Current status of precision medicine in pediatric oncology in Spain: a consensus report by the Spanish Society of Paediatric Haematology and Oncology (SEHOP).

Gargallo, P.; (...); Moreno, L.

Article. 10.1007/s12094-021-02759-7. 2022

  • Open Access.

Challenges in early phase clinical trials for childhood cancer during the COVID-19 pandemic: a report from the new agents group of the Spanish Society of Paediatric Haematology and Oncology (SEHOP).

Rubio-San-Simon, A.; (...); Bautista, F.

Article. 10.1007/s12094-020-02399-3. 2021

  • Open Access.

Childhood and Adolescent Central Nervous System Tumours in Spain: Incidence and Survival over 20 Years: A Historical Baseline for Current Assessment.

Chirlaque MD; (...); The Spanish Childhood Cancer Epidemiology Working Group

Article. 10.3390/cancers15245889. 2023

  • Open Access.

Deletion of 11q in Neuroblastomas Drives Sensitivity to PARP Inhibition

Sanmartin, E; (...); Font de Mora J

Article. 10.1158/1078-0432.CCR-17-0593. 2017

  • Open Access.

Delving into the clinical impact of NETs in pediatric cancer.

Benavent N; (...); Medina P

Article. 10.1038/s41390-024-03437-4. 2024


Development of Hepatoblastoma organoids as a patient-derived ex-vivo system

Zanatto, Laura; (...); Sancho-Bru, Pau

Meeting Abstract. 2022


Development of the ECLIM-SEHOP Clinical Trial Platform: Implementing International Academic Clinical Trials for Childhood Cancer and Blood Disorders in Spain

Fernandez-Teijeiro, A; (...); Moreno, L

Meeting Abstract. 2020


Distribution of segmental chromosomal alterations in neuroblastoma.

Juan Ribelles A; (...); Castel V

Article. 10.1007/s12094-020-02497-2. 2020


Early clinical trials in paediatric oncology in Spain: a nationwide perspective

Bautista, F; (...); Sociedad Española de Hematología y Oncología Pediátrica (SEHOP) and the New Drug

Article. 10.1016/j.anpedi.2016.07.007. 2017

  • Open Access.

ECLIM-SEHOP, a new platform to set up and develop international academic clinical trials for childhood cancer and blood disorders in Spain.

Bautista, F; (...); Sociedad Española de Hematología y Oncología Pediátrica (SEHOP)

Article. 10.1007/s12094-019-02221-9. 2019

  • Open Access.

ECLIM-SEHOP: how to develop a platform to conduct academic trials for childhood cancer.

Juan-Ribelles A; (...); Fernández-Teijeiro A

Article. 10.1007/s12094-024-03445-0. 2024

  • Open Access.

Endocrinological late effects of oncologic treatment on survivors of medulloblastoma

Santos, ADH; (...); Nieto, AC

Article. 10.32641/rchped.v90i6.994. 2019


Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications

Carrillo-Reixach, J; (...); Armengol, C

Article. 10.1016/j.jhep.2020.03.025. 2020

  • Open Access.

Epigenetics and Oxidative Stress in Aging

Guillaumet-Adkins, A; (...); Sandoval, J

Review. 10.1155/2017/9175806. 2017

  • Open Access.

Evaluation of circulating tumor DNA by electropherogram analysis and methylome profiling in high-risk neuroblastomas

Trinidad, Eva Maria; (...); de Mora, Jaime Font

Article. 10.3389/fonc.2023.1037342. 2023

  • Open Access.

EVALUATION OF THE IMPLEMENTATION OF THE RANO CRITERIA IN THE HERBY TRIAL OF PEDIATRIC PATIENTS WITH NEWLY DIAGNOSED HIGH-GRADE GLIOMAS

Rodriguez, D; (...); Jaspan, T

Meeting Abstract. 2018


Event-free survival of infants and toddlers enrolled in the HR-NBL-1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis

Corrias, MV; (...); Burchill, SA

Article. 10.1002/pbc.27052. 2018

  • Open Access.

Exosomal microRNAs from Longitudinal Liquid Biopsies for the Prediction of Response to Induction Chemotherapy in High-Risk Neuroblastoma Patients: A Proof of Concept SIOPEN Study.

Morini M; (...); Varesio L

Article. 10.3390/cancers11101476. 2019

  • Open Access.

Free flaps as a first option for reconstruction of shoulder girdle high recurrence risk tumors.

Pérez-García A; (...); Baixauli F

Letter. 10.1002/jso.26064. 2020


Germline Predisposition to Pediatric Cancer, from Next Generation Sequencing to Medical Care.

Gargallo P; (...); Cañete A

Article. 10.3390/cancers13215339. 2021

  • Open Access.

Germline variant in Ctcf links mental retardation to Wilms tumor predisposition

Gargallo, Pablo; (...); Font de Mora, Jaime

Article. 10.1038/s41431-022-01105-x. 2022


Global Retinoblastoma Presentation and Analysis by National Income Level.

Global Retinoblastoma Study Group; (...); Bowman R

Article. 10.1001/jamaoncol.2019.6716. 2020

  • Open Access.

High Oct4 expression: implications in the pathogenesis of neuroblastic tumours

Monferrer, E; (...); Noguera, R

Article. 10.1186/s12885-018-5219-3. 2019

  • Open Access.

HIGH RISK NEUROBLASTOMA (HR-NB) WITH MNA AND AGE

Ladenstein, Ruth; (...); Canete, Adela

Meeting Abstract. 2023


High risk neuroblastoma (HR-NB) with MNA and age <18 months: Results from the HR-NBL1/SIOPEN trial

Ladenstein, Ruth Lydia; (...); Canete, Adela

Meeting Abstract. 2023


High-risk neuroblastoma: where do we go?

Cañete A

Editorial Material. 10.1016/j.annonc.2019.12.003. 2020

  • Open Access.

Impact of COVID-19 in paediatric early-phase cancer clinical trials in Europe: A report from the Innovative Therapies for Children with Cancer (ITCC) consortium.

Rubio-San-Simón A; (...); Bautista F

Article. 10.1016/j.ejca.2020.09.024. 2020

  • Open Access.

Independent Validation of a Deep Learning nnU-Net Tool for Neuroblastoma Detection and Segmentation in MR Images

Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis

Article. 10.3390/cancers15051622. 2023

  • Open Access.

Influence of Sex on Gestational Complications, Fetal-to-Neonatal Transition, and Postnatal Adaptation

Lorente-Pozo, Sheila; (...); Vento, Maximo

Review. 10.3389/fped.2018.00063. 2018

  • Open Access.

Initial report on Spanish pediatric oncologic, hematologic, and post stem cell transplantation patients during SARS-CoV-2 pandemic

Faura, A; (...); Dapena, JL

Letter. 10.1002/pbc.28557. 2020

  • Open Access.

International benchmarking of childhood cancer survival by tumour stage: First results of the BENCHISTA project

Pritchard-Jones, K.; (...); Gatta, G.

Meeting Abstract. 2024


International benchmarking of stage at diagnosis for six childhood solid tumours (the BENCHISTA project): a population-based, retrospective cohort study.

Botta, Laura; (...); Pritchard-Jones, Kathy

Article. 10.1016/S2352-4642(24)00302-X. 2025


Intratumoral immunosuppression profiles in 11q-deleted neuroblastomas provide new potential therapeutic targets.

Coronado, Esther; (...); Font de Mora, Jaime

Article. 10.1002/1878-0261.12868. 2021

  • Open Access.

Intravitreal melphalan therapy for vitreous seeds in retinoblastoma: Implementation and outcomes of a new chemotherapy protocol.

Solana-Altabella A; (...); Poveda JL

Article. 10.1177/1078155220904410. 2020


IT-Related Barriers and Facilitators to the Implementation of a New European eHealth Solution, the Digital Survivorship Passport (SurPass Version 2.0): Semistructured Digital Survey.

de Beijer, Ismay A E; (...); Chronaki, Catherine

Article. 10.2196/49910. 2024

  • Open Access.

Lateral-type posterior fossa ependymomas in pediatric population

Miranda-Lloret, Pablo; (...); Llavador, Gemma

Article. 10.1016/j.neucir.2023.10.002. 2024

  • Open Access.

Lateral-type posterior fossa ependymomas in pediatric population.

Miranda-Lloret, Pablo; (...); Llavador, Gemma

Article. 10.1016/j.neucie.2023.10.001. 2024


Lenvatinib with etoposide plus ifosfamide in patients with refractory or relapsed osteosarcoma (ITCC-050) : a multicentre, open-label, multicohort, phase 1/2 study

Gaspar, N; (...); Campbell-Hewson, Q

Article. 10.1016/S1470-2045(21)00387-9. 2021

  • Open Access.

Li-Fraumeni syndrome heterogeneity.

Gargallo P; (...); Cañete A

Review. 10.1007/s12094-019-02236-2. 2020


Li-Fraumeni: Will the detection in families increase the survival of its members?

Gargallo, P; (...); Canete, A

Letter. 10.1016/j.anpedi.2018.03.009. 2019

  • Open Access.

Liquid Biopsies of Patients with HIGH-RISK Neuroblastoma Disclose Exosomal miRNA Modulation after the Induction Therapy

Morini, M; (...); Varesio, L

Meeting Abstract. 2017


Liquid Biopsies Provide Exosomal MicroRNAs as Biomarkers of the Response to Induction Chemotherapy in High-Risk Neuroblastoma Patients

Morini, M; (...); Varesio, L

Meeting Abstract. 2018


Liquid Biopsy Micro-RNA Profiling in Meduloblastoma

Yanez, Y; (...); Canete, A

Meeting Abstract. 2018


Liquidhope: methylome and genomic profiling from very limited quantities of plasma-derived DNA.

Trinidad EM; (...); Font de Mora J

Article. 10.1093/bib/bbac575. 2023

  • Open Access.

Long-Term Results for Infants with Neuroblastoma Treated Between 2000 and 2D004 According to INES Protocols -INESFU- A SIOPEN Study

Munzer, C; (...); Gambart, M

Meeting Abstract. 2019


Lymph microvascularization as a prognostic indicator in neuroblastoma.

Tadeo I; (...); Noguera R

Article. 10.18632/oncotarget.25457. 2018

  • Open Access.

Management and outcome of children and adolescents with non-medulloblastoma CNS embryonal tumors in Spain: room for improvement in standards of care

de Rojas, T; (...); Moreno, L

Article. 10.1007/s11060-017-2713-4. 2018


Metabolomic profiling in neuroblastoma.

Quintás G; (...); Segura V

Article. 10.1002/pbc.28113. 2020


Methodological advances in the discovery of novel neuroblastoma therapeutics.

Segura MF; (...); Moreno L

Article. 10.1080/17460441.2022.2002297. 2022


Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs.

Reinal, Ignacio; (...); Sepulveda, Pilar

Article. 10.3390/antiox12071378. 2023

  • Open Access.

Mortality and survival rates in children and adolescents enrolled in early phase trials with a dose-finding/dose-confirmation component: An innovative therapies for children with cancer (ITCC) study.

Carceller, F; (...); Moreno, L

Meeting Abstract. 2019


MR Denoising Increases Radiomic Biomarker Precision and Reproducibility in Oncologic Imaging

Fernández Patón M; (...); Martí-Bonmatí L

Article. 10.1007/s10278-021-00512-8. 2021

  • Open Access.

MRI and Molecular Characterization of Pediatric High-Grade Midline Thalamic Gliomas: The HERBY Phase II Trial.

Rodriguez D; (...); Jaspan T

Article. 10.1148/radiol.211464. 2022

  • Open Access.

MTHFR and VDR Polymorphisms Improve the Prognostic Value of MYCN Status on Overall Survival in Neuroblastoma Patients

Olivera, GG; (...); Herrero, MJ

Article. 10.3390/ijms21082714. 2020

  • Open Access.

Nefroblastoma. Experiencia a largo plazo en el abordaje multidisciplinario.

Rodriguez Iglesias P; (...); Boronat Tormo F

Abstract of Published Item. 2018


Neonatal Suprarenal Masses: An Observational Approach

Papadakis, V; (...); Canete, A

Meeting Abstract. 2018


Neuroblastoma in Spain: Linking the national clinical database and epidemiological registries - A study by the Joint Action on Rare Cancers.

Cañete A; (...); Spanish Neuroblastoma Linkage Working Group (SpNbLinkWG)

Article. 10.1016/j.canep.2022.102145. 2022

  • Open Access.

Next-Generation Sequencing Identifies Potential Actionable Targets in Paediatric Sarcomas

Ribelles, AJ; (...); Canete, A

Article. 10.3390/jpm11040268. 2021

  • Open Access.

Optimising Urinary Catecholamine Diagnostics for Neuroblastoma Patients

Matser, Y; (...); Tytgat, G

Meeting Abstract. 2020


OUTCOME OF BRAF V600E PEDIATRIC GLIOMAS TREATED WITH TARGETED BRAF INHIBITION

Nobre, L; (...); Tabori, U

Meeting Abstract. 2020


Outcomes of BRAF V600E Pediatric Gliomas Treated With Targeted BRAF Inhibition.

Nobre L; (...); Tabori U

Article. 10.1200/PO.19.00298. 2020

  • Open Access.

Pattern and predictors of sites of relapse in neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project.

Vo, Kieuhoa T.; (...); Matthay, Katherine K.

Article. 10.1002/pbc.29616. 2022


Personalized Medicine in Infant Population with Cancer: Pharmacogenetic Pilot Study of Polymorphisms Related to Toxicity and Response to Chemotherapy.

Urtasun, Andrea; (...); Herrero, Maria Jose

Article. 10.3390/cancers15051424. 2023

  • Open Access.

Personalized Medicine: Learning to Walk

Gargallo, P.; (...); Canete, A.

Meeting Abstract. 2018


PHARMACOGENETIC VARIANTS ASSOCIATED WITH TREATMENT RESPONSE IN NEUROBLASTOMA

Olivera, G; (...); Alino, SF

Meeting Abstract. 2018


Pharmacogenetics implementation in the clinics: information and guidelines for germline variants

Olivera, Gladys; (...); Alino, Salvador F.

Review. 10.20517/cdr.2018.25. 2019

  • Open Access.

Pharmacogenetics in Neuroblastoma: What Can Already Be Clinically Implemented and What Is Coming Next?

Olivera, GG; (...); Herrero, MJ

Review. 10.3390/ijms22189815. 2021

  • Open Access.

Phase 1 Combination Dose-Finding/Phase 2 Expansion Cohorts of Lenvatinib plus Etoposide plus Ifosfamide in Patients Aged 2 to <= 25 Years with Relapsed/Refractory Osteosarcoma

Gaspar, N; (...); Campbell-Hewson, Q

Meeting Abstract. 2019


Phase 1 Study of Regorafenib in Combination With Vincristine and Irinotecan in Pediatric Patients With Recurrent or Refractory Solid Tumors

Casanova, M; (...); Geoerger, B

Meeting Abstract. 2020


Phase I combination dose-finding/phase II expansion cohorts of lenvatinib plus etoposide plus ifosfamide in patients (pts) aged 2 to <= 25 years with relapsed/refractory (r/r) osteosarcoma

Gaspar, N; (...); Campbell-Hewson, Q

Meeting Abstract. 2019


Phase I study of regorafenib in combination with vincristine and irinotecan in pediatric patients with recurrent or refractory solid tumors.

Casanova, Michela; (...); Geoerger, Birgit

Meeting Abstract. 2020


Phase I/II study of single-agent lenvatinib in children and adolescents with refractory or relapsed solid malignancies and young adults with osteosarcoma (ITCC-050) ? .

Gaspar N; (...); Casanova M

Article. 10.1016/j.esmoop.2021.100250. 2021

  • Open Access.

Phase II, Open-Label, Randomized, Multicenter Trial (HERBY) of Bevacizumab in Pediatric Patients With Newly Diagnosed High-Grade Glioma

Grill, J; (...); Vassal, G

Article. 10.1200/JCO.2017.76.0611. 2018

  • Open Access.

Plasma Metabolomic Profiling Differentiates High- and Low-Risk Neuroblastoma Patients

Quintas, G; (...); Segura, V

Meeting Abstract. 2018


Precision medicine in Ewing sarcoma: a translational point of view.

Gargallo P; (...); Cañete A

Review. 10.1007/s12094-020-02298-7. 2020


PRIMAGE project: predictive in silico multiscale analytics to support childhood cancer personalised evaluation empowered by imaging biomarkers.

Martí-Bonmatí L; (...); Neri E

Article. 10.1186/s41747-020-00150-9. 2020

  • Open Access.

Prognostic factors of early mortality in children and adolescents enrolled in oncology trials with a dose-finding part in the era of targeted and immune therapies: An Innovative Therapies for Children with Cancer (ITCC) study

Carceller, Fernando; (...); Moreno, Lucas

Meeting Abstract. 2023


Progressively transformed germinal center (PTGC): a challenging diagnosis. Four new pediatric cases

Andres, MM; (...); Fernandez, JM

Meeting Abstract. 2018


Publisher Correction: Clinical Features of Neuroblastoma With 11q Deletion: An Increase in Relapse Probabilities In Localized And 4S Stages.

Juan Ribelles A; (...); Castel V

Correction. 10.1038/s41598-020-58428-2. 2020

  • Open Access.

Radiological evaluation of newly diagnosed non-brainstem pediatric high-grade glioma in the HERBY phase II trial.

Rodriguez Gutierrez D; (...); Jaspan T

Article. 10.1158/1078-0432.CCR-19-3154. 2020

  • Open Access.

Radiotherapy quality assurance in paediatric clinical trials: first report from six QUARTET-affiliated trials.

Kelly, Sarah M.; (...); Mandeville, Henry

Article. 10.1016/j.radonc.2023.109549. 2023

  • Open Access.

Recommended phase 2 dose (RP2D) for abemaciclib in combination with irinotecan (IRN) and temozolomide (TMZ) in pediatric patients with relapsed/refractory solid tumors (JPCS Part A)

Lassaletta, Alvaro; (...); Juan-Ribelles, Antonio

Meeting Abstract. 2023


Regorafenib Plus Vincristine and Irinotecan in Pediatric Patients With Recurrent/Refractory Solid Tumors: An Innovative Therapies for Children With Cancer Study.

Casanova M; (...); Geoerger B

Article. 10.1158/1078-0432.CCR-23-0257. 2023

  • Open Access.

Reproducibility Analysis of Radiomic Features on T2-weighted MR Images after Processing and Segmentation Alterations in Neuroblastoma Tumors.

Veiga-Canuto, Diana; (...); Marti-Bonmati, Luis

Article. 10.1148/ryai.230208. 2024

  • Open Access.

Response rate in cardiac resynchronization therapy patients implanted with a left ventricular quadripolar lead and the MultiPoint(TM) Pacing feature activated. QUARTO III.

Osca, Joaquin; (...); Alzueta, Javier

Article. 10.1111/eci.13935. 2022


Results of a survey on the treatment of adolescents and young adult (AYA) sarcoma patients in Spain at present time.

Mata Fernandez, Cristina; (...); Morales CV

Article. 10.1007/s12094-022-02912-w. 2022


Retinoblastoma and mosaic 13q deletion: a case report

Gargallo P; (...); Canete, A

Article. 10.1186/s40942-021-00321-9. 2021

  • Open Access.

Retinoblastoma: towards an earlier diagnosis.

Gargallo P; (...); Cañete A

Article. 10.1016/j.oftal.2018.05.003. 2018


Review: Ewing Sarcoma Predisposition.

Gargallo P; (...); Cañete A

Article. 10.1007/s12253-019-00765-3. 2019


Risk stratification of high-risk metastatic neuroblastoma: A report from the HR-NBL-1/SIOPEN study

Morgenstern, DA; (...); Ladenstein, R

Article. 10.1002/pbc.27363. 2018


Safety and PK (pharmacokinetic) profile of niraparib (nir) plus dostarlimab (dost) in pediatric patients (pts) with recurrent or refractory (RR) solid tumors: SCOOP study

Doz, Francois; (...); Rubio-San-Simon, Alba

Meeting Abstract. 2023


Single-agent expansion cohort of lenvatinib (LEN) and combination dose-finding cohort of LEN plus etoposide (ETP) plus ifosfamide (IFM) in patients (pts) aged 2 to <= 25 years with relapsed/refractory osteosarcoma (OS).

Gaspar, N; (...); Campbell-Hewson, Q

Meeting Abstract. 10.1200/JCO.2018.36.15_suppl.11527. 2018


Single-Agent Expansion Cohort of Lenvatinib and Combination Dose-Finding Cohort of Lenvatinib plus Etoposide plus Ifosfamide in Patients Aged 2 to <= 25 Years with Relapsed/Refractory Osteosarcoma

Gaspar, N; (...); Campbell-Hewson, Q

Meeting Abstract. 2018


Spinal cord compression syndrome in pediatric oncology: review of a series of cases in a tertiary level center.

Sánchez HM, Guill JB, Zúñiga RV

Case Reports. 10.1016/j.anpede.2024.01.008. 2024

  • Open Access.

Spinal cord compression syndrome in pediatric oncology: Review of a series of cases in a tertiary level center

Sanchez, Helena Martinez, Guill, Julia Balaguer, Zuniga, Roberto Velasco

Letter. 10.1016/j.anpedi.2023.09.013. 2024

  • Open Access.

Staging childhood cancers in Europe: Application of the Toronto stage principles for neuroblastoma and Wilms tumour. The JARC pilot study.

Gatta G; (...); JARC Pilot Study Toronto Guidelines Working Group

Article. 10.1002/pbc.29020. 2021

  • Open Access.

Success of the HR-NBL/SIOPEN local control trial strategy in high risk neuroblastoma patients undergoing high dose therapy with peripheral stem cell transplantation

Ladenstein, R; (...); Botterberg, T

Meeting Abstract. 2018


Successful Second-Line Metronomic Temozolomide in Metastatic Paraganglioma: Case Reports and Review of the Literature.

Tena, I; (...); Pacak, K

Article. 10.1177/1179554918763367. 2018

  • Open Access.

Suprarenal Masses in Very Young Infants: Is It Safe to Watch and Wait? Report of a SIOPEN Observational Study Results

Papadakis, Vassilios; (...); Canete, Adela

Article. 10.3390/cancers14164007. 2022

  • Open Access.

Survey on paediatric tumour boards in Europe: current situation and results from the ExPo-r-Net project

Juan Ribelles A; (...); Ladenstein, R

Article. 10.1007/s12094-017-1820-1. 2018


Survival and Health Care Burden of Children With Retinoblastoma in Europe.

Virgili G; (...); Gatta G

Article. 10.1001/jamaophthalmol.2024.4140. 2024

  • Open Access.

THE BENCHISTA PROJECT: INTERNATIONAL BENCHMARKING OF CHILDHOOD CANCER SURVIVAL BY TUMOUR STAGE

Cortes, Angela Lopez; (...); Pritchard-Jones, Kathy

Article. 2022


The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries

Alia, Donjeta B.; (...); Nyaywa, Mutale

Article. 10.1016/S2214-109X(22)00250-9. 2022

  • Open Access.

The paediatric cancer clinical research landscape in Spain: a 13-year multicentre experience of the new agents group of the Spanish Society of Paediatric Haematology and Oncology (SEHOP)

Rubio-San-Simon, A.; (...); Moreno, L.

Article. 10.1007/s12094-021-02649-y. 2021


TIAM1 variants improve clinical outcome in neuroblastoma

Sanmartin, E; (...); Font de Mora J

Article. 10.18632/oncotarget.16787. 2017

  • Open Access.

Travel burden and clinical presentation of retinoblastoma: analysis of 1024 patients from 43 African countries and 518 patients from 40 European countries.

Fabian, Ido Didi; (...); Bowman, Richard

Article. 10.1136/bjophthalmol-2020-316613. 2020

  • Open Access.

Unraveling the extracellular matrix-tumor cell interactions to aid better targeted therapies for neuroblastoma

Burgos-Panadero, R; (...); Noguera, R

Article. 10.1016/j.ijpharm.2021.121058. 2021

  • Open Access.

Untitled

Castel, V; (...); Zuniga, A

Letter. 10.1007/s12094-018-1889-1. 2018


Vitronectin as a molecular player of the tumor microenvironment in neuroblastoma

Burgos-Panadero, R; (...); Noguera, R

Article. 10.1186/s12885-019-5693-2. 2019

  • Open Access.

Vitronectin Levels in the Plasma of Neuroblastoma Patients and Culture Media of 3D Models: A Prognostic Circulating Biomarker?

Lopez-Carrasco, Amparo; (...); Noguera, Rosa

Article. 10.3390/ijms25168733. 2024

  • Open Access.

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