ESTUDIO ALEATORIZADO, CON DOBLE ENMASCARAMIENTO, DE INICIO DIFERIDO, EN EL QUE SE EVALÚA LY3314814 (AZD3293) EN LA ENFERMEDAD DE ALZHEIMER EN FASE TEMPRANA (AMPLIACIÓN DEL ESTUDIO AZES, EL ESTUDIO AMARANTH).

Dades bàsiques

Protocol:
I8D-MC-AZFD
EURDRACT:
2016-003440-36
NCT:
Centre:
HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
Any inici:
2018
Any de finalització:
2018
ENSAYO CLÍNICO INTERNACIONAL

Documents

  • No hi ha documents

Participants

Grups d'Investigació

Finançadors - Promotors

LILLY, S.A.

Resultats de l'Assaig Clínic


A cross-sectional and longitudinal study on the protective effect of bilingualism against dementia using brain atrophy and cognitive measures.

Costumero V; (...); Ávila C

Article. 10.1186/s13195-020-0581-1. 2020

  • Open Access.

A novel TRMT5 mutation causes a complex inherited neuropathy syndrome: the role of nerve pathology in defining a demyelinating neuropathy.

Argente-Escrig, Herminia; (...); Sevilla, Teresa

Article. 10.1111/nan.12817. 2022

  • Open Access.

A study of the phenotypic variability and disease progression in Laing myopathy through the evaluation of muscle imaging.

Muelas N; (...); Vilchez JJ

Article. 10.1111/ene.14630. 2021


Advances in the early diagnosis of amyotrophic lateral sclerosis.

Garcia-Casanova, Pilar H, Vazquez-Costa, Juan F

Article. 10.1080/14737175.2025.2471556. 2025


Amyloid brain-dedicated PET images can diagnose Alzheimer's pathology with Centiloid Scale.

Gandia-Ferrero MT; (...); Martí-Bonmatí L

Article. 10.1016/j.ejmp.2024.103345. 2024


Analysis of the diagnostic pathway and delay in patients with amyotrophic lateral sclerosis in the Valencian Community.

Vázquez-Costa JF; (...); Sevilla-Mantecón T

Article. 10.1016/j.nrl.2018.03.026. 2018

  • Open Access.

Analysis of the diagnostic pathway and delay in patients with amyotrophic lateral sclerosis in the Valencian Community.

Vazquez-Costa, J F; (...); Sevilla-Mantecon, T

Article. 10.1016/j.nrleng.2018.03.023. 2021

  • Open Access.

Angiotensin II Receptor Blockers Reduce Tau/ASS42 Ratio: A Cerebrospinal Fluid Biomarkers' Case-Control Study.

Garcia-Lluch, Gemma; (...); Chafer-Pericas, Consuelo

Article. 10.3390/pharmaceutics15030924. 2023

  • Open Access.

Argon laser peripheral iridoplasty and anterior segment optical coherence tomography in the management of acute angle closure in the 21st century.

Placinta IA; (...); Vila-Arteaga J

Article. 10.1016/j.oftal.2018.03.004. 2018


Artificial Intelligence on FDG PET Images Identifies Mild Cognitive Impairment Patients with Neurodegenerative Disease.

Prats-Climent, Joan; (...); Marti-Bonmati, Luis

Article. 10.1007/s10916-022-01836-w. 2022

  • Open Access.

Assessment of apolipoprotein E genotype for ß-amyloid status prediction.

Peña-Bautista C; (...); Chafer-Pericas, Consuelo

Article. 10.2174/1567205019666211223141524. 2021


Assessment of COVID-19 lockdown effect on early Alzheimer Disease progression.

Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo

Article. 10.1007/s00415-023-11899-5. 2023


Assessment of lipid peroxidation and artificial neural network models in early Alzheimer Disease diagnosis.

Peña-Bautista C; (...); Cháfer-Pericás C

Article. 10.1016/j.clinbiochem.2019.07.008. 2019

  • Open Access.

Assessment of Lipid Peroxidation in Alzheimer's Disease Differential Diagnosis and Prognosis.

Ferre-Gonzalez, Laura; (...); Chafer-Pericas, Consuelo

Article. 10.3390/antiox11030551. 2022

  • Open Access.

Assessment of Plasma and Cerebrospinal Fluid Biomarkers in Different Stages of Alzheimer's Disease and Frontotemporal Dementia.

Álvarez-Sánchez L; (...); Cháfer-Pericás C

Article. 10.3390/ijms24021226. 2023

  • Open Access.

Assessment of Screening Approach in Early and Differential Alzheimer's Disease Diagnosis.

Ferré-González L; (...); Cháfer-Pericás C

Article. 10.3390/antiox10111662. 2021

  • Open Access.

Associations between antidiabetic medications and cerebrospinal fluid biomarkers of Alzheimer's disease.

Garcia-Lluch, Gemma; (...); Chafer-Pericas, Consuelo

Article. 10.1177/13872877241304995. 2024

  • Open Access.

Attitudes toward seeking professional help among patients with early Alzheimer's disease

Villarejo-Galende, A.; (...); Maurino, J.

Meeting Abstract. 2023


ATYPICAL HEALING IN A CASE WITH RETINAL PIGMENT EPITHELIUM APERTURES.

Molina-Pallete R; (...); Dolz-Marco R

Article. 10.1097/ICB.0000000000000789. 2018


Awareness of Diagnosis in Persons with Early-Stage Alzheimer's Disease: An Observational Study in Spain.

Villarejo-Galende, Alberto; (...); Maurino, Jorge

Article. 10.1007/s40120-022-00367-3. 2022

  • Open Access.

Brain signal intensity changes as biomarkers in amyotrophic lateral sclerosis

Vazquez-Costa, JF; (...); Sevilla, T

Article. 10.1111/ane.12863. 2018

  • Open Access.

Cardiovascular Risk Scales Association with Cerebrospinal Fluid Alzheimer's Disease Biomarkers in Cardiovascular Low Cardiovascular Risk Regions.

García-Lluch G; (...); Cháfer-Pericás C

Article. 10.14283/jpad.2024.16. 2024


Clinical and genetic characteristics of 21 Spanish patients with biallelic pathogenic SPG7 mutations.

Baviera-Muñoz R; (...); Espinós C

Article. 10.1016/j.jns.2021.118062. 2021


Clinical and Magnetic Resonance Imaging features of a series of 11 Spanish patients who carry mutations in the BICD2 gene

Carrera, MF; (...); Sevilla, T

Meeting Abstract. 2018


Clinical features, mutation spectrum and factors related to reaching molecular diagnosis in a cohort of patients with distal myopathies.

Muelas, Nuria; (...); Vilchez, Juan J

Article. 10.1007/s00415-024-12821-3. 2025


Clinical spectrum of BICD2 mutations.

Frasquet M; (...); Sevilla T

Article. 10.1111/ene.14173. 2020


Clinical trials in pediatric ALS: a TRICALS feasibility study.

Kliest T; (...); Van Den Berg LH

Article. 10.1080/21678421.2021.2024856. 2022

  • Open Access.

Clinical usefulness of cerebrospinal fluid biomarkers in Alzheimer Disease.

Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo

Article. 10.1111/eci.13910. 2022


Clinical Utility of Plasma Lipid Peroxidation Biomarkers in Alzheimer's Disease Differential Diagnosis

Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo

Article. 10.3390/antiox9080649. 2020

  • Open Access.

COGNITIVE FUNCTION FOLLOWING AN INTRACEREBRAL HEMORRHAGE ASSOCIATED WITH CEREBRAL AMYLOID ANGIOPATHY.

Gimenez, C; (...); Lago, A

Meeting Abstract. 2020


Characterising the phenotype and mode of inheritance of patients with inherited peripheral neuropathies carrying MME mutations

Lupo, V; (...); SEVILLA, T

Article. 10.1136/jmedgenet-2018-105650. 2018


Characterizing SOD1 mutations in Spain. The impact of genotype, age, and sex in the natural history of the disease.

Vazquez-Costa, Juan F.; (...); Garcia-Redondo, Alberto

Article. 10.1111/ene.15661. 2022

  • Open Access.

Charcot-Marie-Tooth disease due to MORC2 mutations in Spain

Sivera R; (...); Sevilla T

Article. 10.1111/ene.15001. 2021

  • Open Access.

Decreased spasticity in primary lateral sclerosis after botulinum toxin injection: A case report

Cea, AA; (...); Salazar, MG

Letter. 10.1016/j.nrl.2016.01.005. 2018

  • Open Access.

Defining Alzheimer's Disease through Proteomic CSF Profiling.

Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo

Article. 10.1021/acs.jproteome.4c00590. 2024


Delphi consensus on recommendations for the treatment of spinal muscular atrophy in Spain (RET-AME consensus)

Pitarch Castellano, I; (...); Vazquez-Costa, J. F.

Article. 10.1016/j.nrl.2021.07.008. 2022

  • Open Access.

Delphi consensus on recommendations for the treatment of spinal muscular atrophy in Spain (RET-AME consensus).

Pitarch Castellano I; (...); Vázquez-Costa JF

Practice Guideline. 10.1016/j.nrleng.2021.07.002. 2022


Depression and Suicide Risk in Mild Cognitive Impairment: The Role of Alzheimer's Disease Biomarkers

Ferrer-Cairols, Ines; (...); Salvador, Alicia

Article. 10.7334/psicothema2022.103. 2022

  • Open Access.

Descriptive analysis of the spinal muscular atrophy population treated with Nusinersen included in the CuidAME project

Sotoca Fernandez, J.; (...); Fernandez-Garcia, M.

Meeting Abstract. 10.1016/j.nmd.2024.07.462. 2024

  • Open Access.

Design and Validation of a Clinical Outcome Measure for Adolescents and Adult Patients with Spinal Muscular Atrophy: SMA Life Study Protocol

Rebollo, Pablo; (...); Vazquez-Costa, Juan F.

Article. 10.1007/s40120-023-00571-9. 2024

  • Open Access.

Design of a Non-Interventional Study to Validate a Set of Patient- and Caregiver-Oriented Measurements to Assess Health Outcomes in Spinal Muscular Atrophy (SMA-TOOL Study).

Madruga-Garrido M; (...); Maurino J

Article. 10.1007/s40120-020-00229-w. 2021

  • Open Access.

Diagnostic delay and pathway analysis in paediatric Charcot-Marie-Tooth disease

Argente-Escrig, H; (...); Mantecon, MTS

Meeting Abstract. 2019


Diagnostic Efficacy of Genetic Studies in a Series of Hereditary Cerebellar Ataxias in Eastern Spain.

Baviera-Munoz, Raquel; (...); Aller, Elena

Article. 10.1212/NXG.0000000000200038. 2022

  • Open Access.

Discordant Amyloid Status Diagnosis in Alzheimer's Disease.

García-Vallés L; (...); Cháfer-Pericás C

Article. 10.3390/biomedicines10112880. 2022

  • Open Access.

Distal hereditary motor neuropathies: mutation spectrum and genotype-phenotype correlation.

Frasquet, Marina; (...); Lupo, Vincenzo

Article. 10.1111/ene.14700. 2021


Do we really need to calculate a minimal important difference for ALSFRS-R?: A letter in response to 'Clinically meaningful change: evaluation of the Rasch-built Overall Amyotrophic Lateral Sclerosis Disability Scale (ROADS) and the ALSFRS-R' published in Vol. 24(3-4), pp. 311-316

Vázquez-Costa JF

Article. 10.1080/21678421.2023.2248199. 2024


Early Alzheimer's Disease Screening Approach Using Plasma Biomarkers

Alvarez-Sanchez, Lourdes; (...); Chafer-Pericas, Consuelo

Article. 10.3390/ijms241814151. 2023

  • Open Access.

Early neurotransmission impairment in non-invasive Alzheimer Disease detection

Pena-Bautista, Carmen; (...); Cháfer-Pericás C

Article. 10.1038/s41598-020-73362-z. 2020

  • Open Access.

Effects of bilingualism on white matter atrophy in mild cognitive impairment: a diffusion tensor imaging study.

Marin-Marin L; (...); Ávila C

Article. 10.1111/ene.14135. 2020

  • Open Access.

Emotion recognition and baseline cortisol levels relationship in early Alzheimer Disease.

Ferrer-Cairols, I.; (...); Chafer-Pericas, C.

Article. 10.1016/j.biopsycho.2023.108511. 2023


Epigenomics and Lipidomics Integration in Alzheimer Disease: Pathways Involved in Early Stages.

Peña-Bautista C; (...); Chafer-Pericas, Consuelo

Article. 10.3390/biomedicines9121812. 2021

  • Open Access.

Estimation of the prevalence and incidence of motor neuron diseases in two Spanish regions: Catalonia and Valencia.

Barceló MA; (...); Saez M

Article. 10.1038/s41598-021-85395-z. 2021

  • Open Access.

Facial Onset Sensory and Motor Neuronopathy New Cases, Cognitive Changes, and Pathophysiology

de Boer, EMJ; (...); van Es, MA

Review. 10.1212/CPJ.0000000000000834. 2021

  • Open Access.

Facial onset sensory and motor neuronopathy: a motor neuron disease with an oligogenic origin?

Vazquez-Costa, JF; (...); Sevilla, T

Article. 10.1080/21678421.2019.1582671. 2019


Fast Declining Prediction in Alzheimer's Disease from Early Clinical Assessment.

Álvarez-Sánchez L; (...); Pericás CC

Article. 10.2174/011570159X332930240925095423. 2024


Fatigue, pain, breathing, voice, fatigability, sleep, rest and vulnerability as meaningful outcomes in SMA care: the patients ' and caregivers' voice

Povedano, M.; (...); Rebollo, P.

Meeting Abstract. 10.1016/j.nmd.2022.07.209. 2022

  • Open Access.

Free radicals in Alzheimer's disease: Lipid peroxidation biomarkers

Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo

Review. 10.1016/j.cca.2019.01.021. 2019


Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project

Moreno-Grau, S; (...); GR ACE Study Grp

Article. 10.1016/j.jalz.2019.06.4950. 2019

  • Open Access.

Imaging Biomarkers for the Diagnosis and Prognosis of Neurodegenerative Diseases. The Example of Amyotrophic Lateral Sclerosis

Mazon, M; (...); Marti-Bonmati, L

Review. 10.3389/fnins.2018.00784. 2018

  • Open Access.

Imaging Biomarkers in Amyotrophic Lateral Sclerosis

Cerda Alberich, Leonor; (...); Marti-Bonmati, Luis

Editorial Material. 10.1007/978-1-0716-1712-0_20. 2022

  • Open Access.

Impact of SARS-CoV-2 infection and COVID-19 pandemic on the morbidity and mortality of amyotrophic lateral sclerosis patients in Valencia, Spain

Garcia-Casanova, Pilar H.; (...); Vazquez-Costa, Juan F.

Article. 10.1111/ene.16465. 2024

  • Open Access.

Improving Care and Empowering Adults Living with SMA: A Call to Action in the New Treatment Era.

Walter MC; (...); Servais L

Article. 10.3233/JND-200611. 2021

  • Open Access.

Insights from a 7-Year Dementia Cohort (VALCODIS): ApoE Genotype Evaluation.

Baquero, Miguel; (...); Chafer-Pericas, Consuelo

Article. 10.3390/jcm13164735. 2024

  • Open Access.

Insights into phenotypic variability caused by GARS1 pathogenic variants.

Jiménez-Jiménez J; (...); Sivera R

Article. 10.1111/ene.16416. 2024

  • Open Access.

Intermediate Repeat Expansion in the ATXN2 Gene as a Risk Factor in the ALS and FTD Spanish Population.

Borrego-Hernandez, Daniel; (...); Garcia-Redondo, Alberto

Article. 10.3390/biomedicines12020356. 2024

  • Open Access.

Isoprostanoids Levels in Cerebrospinal Fluid Do Not Reflect Alzheimer's Disease

Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo

Article. 10.3390/antiox9050407. 2020

  • Open Access.

La reserva cognitiva como factor modulador del impacto de la cirugía sobre la memoria visual y la denominación en pacientes con epilepsia del lóbulo temporal.

Cano-Lopez, I; (...); Gonzalez-Bono, E

Article. 10.33588/rn.7308.2021109. 2021


Lifesaving Treatments for Spinal Muscular Atrophy: Global Access and Availability

Armengol, Victor D.; (...); Roy, Bhaskar

Meeting Abstract. 2023


Life-Saving Treatments for Spinal Muscular Atrophy: Global Access and Availability.

Armengol, Victor D; (...); Roy, Bhaskar

Article. 10.1212/CPJ.0000000000200224. 2024

  • Open Access.

Lipid Peroxidation Assessment in Preclinical Alzheimer Disease Diagnosis

Pena-Bautista, Carmen; (...); Cháfer-Pericás C

Article. 10.3390/antiox10071043. 2021

  • Open Access.

Lipid peroxidation biomarkers correlation with medial temporal atrophy in early Alzheimer Disease

Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo

Article. 10.1016/j.neuint.2019.104519. 2019


Lipid peroxidation in neurodegeneration.

Peña-Bautista C; (...); Cháfer-Pericás C

Review. 10.1016/j.cca.2019.07.037. 2019


Lipids as early and minimally invasive biomarkers for Alzheimer disease.

Casas-Fernandez, Esther; (...); Chafer-Pericas, Consuelo

Article. 10.2174/1570159X19666211102150955. 2021

  • Open Access.

Manipulación de fármacos para su administración por gastrostomía endoscópica percutánea en pacientes con esclerosis lateral amiotrófica y nutrición enteral.

Vázquez Polo A; (...); Vázquez Costa JF

Article. 10.20960/nh.03946. 2022

  • Open Access.

Measuring Outcomes in Adults with Spinal Muscular Atrophy - Challenges and Future Directions - Meeting Report.

Sansone VA; (...); Hagenacker T

Article. 10.3233/JND-200534. 2020


MEASURING THE EXPERIENCE OF LIVING WITH SPINAL MUSCULAR ATROPHY: THE ROLE OF THE SMA INDEPENDENCE SCALE

Vazquez, J. F.; (...); Madruga, M.

Meeting Abstract. 2022


Medical help-seeking intentions among patients with early Alzheimer's disease

Villarejo-Galende, Alberto; (...); Maurino, Jorge

Article. 10.3389/fpsyt.2023.1290002. 2023

  • Open Access.

Metabolomics study to identify plasma biomarkers in alzheimer disease: ApoE genotype effect.

Peña-Bautista C; (...); Cháfer-Pericás C

Article. 10.1016/j.jpba.2019.113088. 2020


Minimal detectable change and minimal clinically important difference in spinal muscular atrophy patients.

Vázquez-Costa JF, Hervás D

Letter. 10.1111/ene.14780. 2021


Misfolded alpha-synuclein detection by RT-QuIC in dementia with lewy bodies: a systematic review and meta-analysis.

Peña-Bautista C; (...); Ferreira D

Article. 10.3389/fmolb.2023.1193458. 2023

  • Open Access.

Moral reasoning and moral conflict in patients of the amyotrophic lateral sclerosis - Frontotemporal dementia spectrum.

Serrano-Pastor, Lucas; (...); Vazquez-Costa, Juan F

Article. 10.1080/17470919.2020.1850521. 2020


Multimodal non-invasive imaging in choroidal rupture secondary to a firework explosion.

Placinta IA; (...); Cisneros-Lanuza Á

Case Reports. 10.1016/j.oftal.2018.06.009. 2019


Mutations in MME cause autosomal recessive late-onset CMT type-2 disease

Carrera, MF; (...); Sevilla, T

Meeting Abstract. 2018


Natural history data in adults with SMA

Vazquez-Costa, JF

Letter. 10.1016/S1474-4422(20)30183-6. 2020

  • Open Access.

Neurodegeneration Biomarkers in Adult Spinal Muscular Atrophy (SMA) Patients Treated with Nusinersen

Andres-Benito, Pol; (...); Povedano, Monica

Article. 10.3390/ijms25073810. 2024

  • Open Access.

Neuropsychological assessment and cortisol levels in biofluids from early Alzheimer's disease patients

Pena-Bautista, C.; (...); Chafer-Pericas, C.

Article. 10.1016/j.exger.2019.05.007. 2019


New approach for early and specific Alzheimer disease diagnosis from different plasma biomarkers.

Forte, Anabel; (...); Chafer-Pericas, Consuelo

Article. 10.1016/j.cca.2024.117842. 2024


New insights into the genetic etiology of Alzheimer's disease and related dementias

Bellenguez, Celine; (...); CHARGE

Article. 10.1038/s41588-022-01024-z. 2022

  • Open Access.

New insights into the pathophysiology of fasciculations in amyotrophic lateral sclerosis: An ultrasound study

Vazquez-Costa, JF; (...); Sevilla, T

Article. 10.1016/j.clinph.2018.09.014. 2018


New screening approach for Alzheimer's disease risk assessment from urine lipid peroxidation compounds.

Peña-Bautista C; (...); Chafer-Pericas, C

Article. 10.1038/s41598-019-50837-2. 2019

  • Open Access.

Novel Ultrasensitive Detection Technologies for the Identification of Early and Minimally Invasive Alzheimer's Disease Blood Biomarkers.

Alvarez-Sanchez, Lourdes; (...); Chafer-Pericas, Consuelo

Article. 10.3233/JAD-215093. 2022


Nusinersen in adult patients with 5q spinal muscular atrophy: Amulticenter observational cohorts' study.

Vazquez-Costa, Juan F.; (...); Hervas, David

Article. 10.1111/ene.15501. 2022

  • Open Access.

Obstructive sleep apnea and Alzheimer's disease-related cerebrospinal fluid biomarkers in mild cognitive impairment.

Díaz-Román M; (...); Gómez E

Article. 10.1093/sleep/zsaa133. 2021

  • Open Access.

Omics-based Biomarkers for the Early Alzheimer Disease Diagnosis and Reliable Therapeutic Targets Development

Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo

Review. 10.2174/1570159X16666180926123722. 2019

  • Open Access.

Oxidative Damage of DNA as Early Marker of Alzheimer's Disease.

Peña-Bautista C; (...); Cháfer-Pericás C

Article. 10.3390/ijms20246136. 2019

  • Open Access.

Pediatric inherited peripheral neuropathy: a prospective study at a Spanish referral center

Argente-Escrig H; (...); Sevilla T

Article. 10.1002/acn3.51432. 2021

  • Open Access.

Person-centered Assessment in Early Alzheimers Disease (P1-1.Virtual)

Villarejo Galende, Alberto; (...); Maurino, Jorge

Meeting Abstract. 2022


Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer's disease: randomized, double-blind, placebo-controlled study

Timmers, M; (...); Engelborghs, S

Article. 10.1186/s13195-018-0415-6. 2018

  • Open Access.

Phenotypical features of two patients diagnosed with PHARC syndrome and carriers of a new homozygous mutation in the ABHD12 gene

Frasquet, M; (...); Sevilla, T

Article. 10.1016/j.jns.2018.02.021. 2018


Plasma alterations in cholinergic and serotonergic systems in early Alzheimer Disease: Diagnosis utility.

Peña-Bautista C; (...); Cháfer-Pericás C

Article. 10.1016/j.cca.2019.10.023. 2020


Plasma isoprostanoids assessment as Alzheimer's disease progression biomarkers.

Peña-Bautista C; (...); Cháfer-Pericás C

Article. 10.1111/jnc.15183. 2020

  • Open Access.

Plasma lipid peroxidation biomarkers for early and non-invasive Alzheimer Disease detection

Pena-Bautista, C; (...); Chafer-Pericas, C

Article. 10.1016/j.freeradbiomed.2018.06.038. 2018


Plasma Lipidomics Approach in Early and Specific Alzheimer's Disease Diagnosis.

Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo

Article. 10.3390/jcm11175030. 2022

  • Open Access.

Plasma metabolomics in early Alzheimer's disease patients diagnosed with amyloid biomarker

Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo

Article. 10.1016/j.jprot.2019.04.008. 2019


Potential oxidative stress biomarkers of mild cognitive impairment due to Alzheimer disease

Garcia-Blanco, Ana; (...); Chafer-Pericas, Consuelo

Review. 10.1016/j.jns.2017.01.020. 2017


Presenilin-1 Mutations Are a Cause of Primary Lateral Sclerosis-Like Syndrome

Vazquez-Costa, JF; (...); SEVILLA, T

Article. 10.3389/fnmol.2021.721047. 2021

  • Open Access.

Prognostic value of cerebrospinal fluid biomarkers in mild cognitive impairment due to Alzheimer disease.

López-Cuevas R; (...); Cháfer-Pericás C

Article. 10.1016/j.nrl.2020.07.026. 2020

  • Open Access.

Prognostic value of cerebrospinal fluid biomarkers in mild cognitive impairment due to Alzheimer disease.

Lopez-Cuevas, R; (...); Chafer-Pericas, C

Article. 10.1016/j.nrleng.2020.07.024. 2023


Quantitative neuromuscular ultrasound analysis as biomarkers in amyotrophic lateral sclerosis

Rios-Diaz, J; (...); Martinez-Paya, JJ

Article. 10.1007/s00330-018-5943-8. 2019


Recent evidence in epigenomics and proteomics biomarkers for early and minimally invasive diagnosis of Alzheimer's and Parkinson's diseases.

Mayo, Sonia; (...); Chafer-Pericas, Consuelo

Review. 10.2174/1570159X19666201223154009. 2020

  • Open Access.

Relationship between neuroimaging and emotion recognition in Mild Cognitive Impairment patients.

Gandia-Ferrero, Maria Teresa; (...); Marti-Bonmati, Luis

Article. 10.1016/j.bbr.2023.114844. 2024


Relationship between Plasma Lipid Profile and Cognitive Status in Early Alzheimer Disease.

Pena-Bautista, Carmen; (...); Chafer-Pericas, Consuelo

Article. 10.3390/ijms25105317. 2024

  • Open Access.

Relevance of the interplay between amyloid and tau for cognitive impairment in early Alzheimer's disease

Timmers, M; (...); Streffer, JR

Article. 10.1016/j.neurobiolaging.2019.03.016. 2019

  • Open Access.

Reliable determination of new lipid peroxidation compounds as potential early Alzheimer Disease biomarkers

Garcia-Blanco, Ana; (...); Chafer-Pericas, Consuelo

Article. 10.1016/j.talanta.2018.03.002. 2018

  • Open Access.

Risdiplam in non-sitter patients aged 16years and older with 5q spinal muscular atrophy.

Nungo Garzon, Nancy Carolina; (...); Vazquez-Costa, Juan F

Article. 10.1002/mus.27804. 2023

  • Open Access.

Role of the nigrosome 1 absence as a biomarker in amyotrophic lateral sclerosis

Isabel Moreno-Gambin, Maria; (...); Vázquez-Costa JF

Article. 10.1007/s00415-021-10729-w. 2021

  • Open Access.

SONOELASTOGRAPHY FOR THE ASSESSMENT OF MUSCLE CHANGES IN AMYOTROPHIC LATERAL SCLEROSIS: RESULTS OF A PILOT STUDY

Martinez-Paya, JJ; (...); Vazquez-Costa, JF

Article. 10.1016/j.ultrasmedbio.2018.08.009. 2018


Spinal Muscular Atrophy Update in Best Practices: Recommendations for Diagnosis Considerations.

Schroth, Mary; (...); Vazquez-Costa, Juan F.

Article. 10.1212/CPJ.0000000000200310. 2024

  • Open Access.

STATISTICAL SOLUTIONS FOR ANALYTIC CHALLENGES IN REGISTRIES FOR HTA-PURPOSES

Fekete, I; (...); Volmer, T

Meeting Abstract. 2020


Stress and neurodegeneration.

Peña-Bautista C; (...); Cháfer-Pericás C

Review. 10.1016/j.cca.2020.01.019. 2020


The cross-sectional area of the median nerve: An independent prognostic biomarker in amyotrophic lateral sclerosis

Martinez-Paya, J. J.; (...); Vazquez-Costa, J. F.

Article. 10.1016/j.nrl.2022.01.008. 2024

  • Open Access.

The cross-sectional area of the median nerve: An independent prognostic biomarker in amyotrophic lateral sclerosis.

Martinez-Paya, J J; (...); Vazquez-Costa, J F

Article. 10.1016/j.nrleng.2024.07.003. 2024

  • Open Access.

The MAPT H1 Haplotype Is a Risk Factor for Alzheimer's Disease in APOE epsilon 4 Non-carriers

Sanchez-Juan, P; (...); DEGESCO Consortium

Article. 10.3389/fnagi.2019.00327. 2019

  • Open Access.

The width of the third ventricle associates with cognition and behaviour in motor neuron disease

Vazquez-Costa, JF; (...); Sevilla, T

Article. 10.1111/ane.13022. 2019

  • Open Access.

Tocilizumab as first treatment option in optic neuropathy secondary to Graves' orbitopathy.

Pascual-Camps I; (...); Espana-Gregori E

Article. 10.1080/01676830.2018.1435694. 2018


Treatment of patients with spinal muscular atrophy 5q: Towards a new protocol.

Gomez-Andres, D., Martinez-Moreno, M., Vazquez-Costa, J. F.

Letter. 10.1016/j.nrl.2020.10.003. 2021

  • Open Access.

Treatment of patients with spinal muscular atrophy 5q: towards a new protocol.

Gómez-Andrés D, Martínez-Moreno M, Vázquez-Costa JF

Letter. 10.1016/j.nrleng.2020.10.005. 2021

  • Open Access.

Treatment of spinal muscular atrophy in European countries: A call to action

Vazquez-Costa, Juan F.; (...); Cattinari, Maria Grazia

Article. 10.1111/ene.15522. 2022


Ultrasound-guided lumbar puncture for nusinersen administration in spinal muscular atrophy patients.

Veiga-Canuto D; (...); Aparici F

Article. 10.1111/ene.14586. 2021


Urinary symptoms in patients with amyotrophic lateral sclerosis.

Vázquez-Costa JF, Arlandis S

Letter. 10.1016/j.nrl.2019.01.003. 2020

  • Open Access.

Use of Tachosil (R) as an adjuvant therapeutic option in neurotrophic keratopathy in order to prevent perforation

Rahhal-Ortuno, M; (...); Cisneros-Lanuza, AL

Article. 10.4103/ijo.IJO_1573_18. 2019

  • Open Access.

Validated analytical method to determine new salivary lipid peroxidation compounds as potential neurodegenerative biomarkers.

Peña-Bautista C; (...); Cháfer-Pericás C

Article. 10.1016/j.jpba.2018.11.043. 2019

  • Open Access.

Validation of a Set of Instruments to Assess Patient- and Caregiver-Oriented Measurements in Spinal Muscular Atrophy: Results of the SMA-TOOL Study.

Vazquez-Costa, Juan F.; (...); Madruga-Garrido, Marcos

Article. 10.1007/s40120-022-00411-2. 2022

  • Open Access.

Validation of Neuromyotype: A smart keyboard for the evaluation of spinal muscular atrophy patients

Lizandra Cortes, P.; (...); Vazquez-Costa, J. F.

Article. 10.1016/j.nrl.2022.05.004. 2024

  • Open Access.

Validation of Neuromyotype: A smart keyboard for the evaluation of spinal muscular atrophy patients.

Cortes, P Lizandra; (...); Vázquez-Costa JF

Article. 10.1016/j.nrleng.2022.05.001. 2022

  • Open Access.

Zeus, the look through the anophthalmic cavity.

Placinta IA; (...); España-Gregori E

Article. 10.1016/j.oftal.2019.01.011. 2019


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