Regenerative medicine based on bioengineering for human reproduction.

Article. 10.1016/j.bioadv.2023.213480. 2023

Bioengineered endometrial hydrogels with growth factors promote tissue regeneration and restore fertility in murine models.

Lopez-Martinez, Sara; (...); Cervello, Irene

Article. 10.1016/j.actbio.2021.08.025. 2021

Bioengineering an Ovarian-Specific ECM Hydrogel to Treat Premature Ovarian Failure

Meeting Abstract. 2023

Bioengineering Endometrial Extracellular Matrix Hydrogels: A New Option to Improve Human Three-dimensional Endometrial Cell Culture and Organoid Development.

Lopez-Martinez, S; (...); Cervello, I

Meeting Abstract. 2020

Bioengineering trends in female reproduction: a systematic review

Frances-Herrero, Emilio; (...); Cervello, Irene

Review. 10.1093/humupd/dmac025. 2022

Biotechnological progresses in modelling the human endometrium: the evolution of current in vitro techniques and emerging trends.

Agustina-Hernandez, Marcos; (...); Cervello, Irene

Article. 10.3389/fbioe.2024.1495338. 2024

Comparison of different sources of platelet-rich plasma as treatment option for infertility-causing endometrial pathologies.

de Miguel-Gómez L; (...); Cervelló I

Article. 10.1016/j.fertnstert.2020.07.053. 2020

COVID19-free endometrium: Undetectable viral RNA in endometrial biopsies from positive symptomatic SARS-CoV-2 women

De Miguel-Gomez, L; (...); Cervello, I

Meeting Abstract. 2021

Decellularization Methods of Ovary in Tissue Engineering.

Campo H, López-Martínez S, Cervelló I

Article. 10.1007/978-3-030-82735-9_11. 2021

Decellularization Methods of Vagina and Cervix in Tissue Engineering.

López-Martínez S, Campo H, Cervelló I

Article. 10.1007/978-3-030-82735-9_13. 2021

Development of Decellularized Oviductal Hydrogels as a Support for Rabbit Embryo Culture.

Francés-Herrero E; (...); Cervelló I

Article. 10.1007/s43032-020-00446-6. 2021

DEVELOPMENT OF SECRETOR AND GESTATIONAL PATIENT-DERIVED ORGANOIDS FROM ADENOMYOSIS DISEASE AS AN IN VITRO MODELTO STUDY ADENOMYOSIS-RELATED INFERTILITY AND PERSONALIZED DRUG SCREENING.

Juarez-Barber, Elena; (...); Ferrero, Hortensia

Meeting Abstract. 2021

EFFECT OF HUMAN UMBILICAL CORD BLOOD PLATELET-RICH PLASMA COMBINED WITH EXTRACELLULAR MATRIX HYDROGELS ON IMMUNOCOMPETENT ENDOMETRIAL DAMAGE: MURINE MODELS

Rodriguez Eguren, Adolfo; (...); Cervello, Irene

Meeting Abstract. 2022

Effects of In Vitro Culture Systems with Fallopian Tube Extracellular Matrix on Rabbit Embryo Gene Expression.

Meeting Abstract. 2024

Endometrial Extracellular Matrix Hydrogel Alleviates Epithelial-toMesenchymal Transition Triggered by Human Umbilical Cord PlateletRich Plasma in Human Endometrial Organoids.

Meeting Abstract. 2024

Endometrial Extracellular Matrix Hydrogels as Alternatives to Matrigel for Culturing Human Endometrial Organoids

Gomez-Alvarez, Maria; (...); Cervello, Irene

Meeting Abstract. 2023

Endometrial extracellular vesicles regulate processes related to embryo development and implantation in human blastocysts

Segura-Benitez, Marina; (...); Ferrero, Hortensia

Article. 10.1093/humrep/deae256. 2024

Enhancing Development of Murine Follicles In Vitro Using Extracellular Matrix from Decellularized Bovine Ovarian Cortex

Meeting Abstract. 2022

EPITHELIAL-TO-MESENCHYMAL TRANSITION INDUCTION BY HUMAN UMBILICAL CORD PLATELET-RICH PLASMA IN HUMAN ENDOMETRIAL ORGANOIDS: DIFFERENTIATION STATE MATTERS

Agustina-Hernandez, Marcos; (...); Cervello, Irene

Meeting Abstract. 10.1016/j.fertnstert.2024.07.263. 2024

Establishment of Adenomyosis Organoids as a Preclinical Model to Study Infertility.

Article. 10.3390/jpm12020219. 2022

Evolution of biotechnological advances and regenerative therapies for endometrial disorders: a systematic review.

Article. 10.1093/humupd/dmae013. 2024

Extracellular Matrix Hydrogels from Decellularized Endometrium Promote Tissue Regeneration and Fertility Restoration in a Murine Model of Endometrial Damage.

Lopez-Martinez, S; (...); Cervello, I

Meeting Abstract. 2021

EXTRACELLULAR VESICLES SECRETED BY ENDOMETRIAL ORGANOIDS FROM ADENOMYOSIS PATIENTS CONTAIN MIRNAS IMPLICATED IN DISEASE DEVELOPMENT, EMBRYO IMPLANTATION FAILURE AND PREGNANCY DISORDERS

Meeting Abstract. 2022

Fallopian tube extracellular matrix hydrogels for in vitro embryo culture in rabbit models: A post-natal study

Frances, E.; (...); Cervello, I.

Meeting Abstract. 2022

Future Challenges and Opportunities of Extracellular Matrix Hydrogels in Female Reproductive Medicine

Francés-Herrero E; (...); Cervelló I

Article. 10.3390/ijms23073765. 2022

Generation of Complex 3D Human Endometrial Assembloids with Epithelial Organoids and Stromal Stem Cell Lines.

Meeting Abstract. 2022

GLOBAL DELETION OF MITOCHONDRIAL PINK1 GENE INDUCES LOSS OF FOLLICULAR RESERVE AND PRODUCES FEMALE INFERTILITY

Rodriguez Eguren, Adolfo; (...); Seli, Emre

Meeting Abstract. 2023

Growth Factor-Enriched Xenogeneic Ovarian ECM Hydrogels: A Promising Treatment for Premature Ovarian Failure.

Meeting Abstract. 2024

Growth factor-loaded ovarian extracellular matrix hydrogels promote in vivo ovarian niche regeneration and enhance fertility in premature ovarian insufficiency preclinical models.

Article. 10.1016/j.actbio.2024.07.056. 2024

H3K4me3 mediates uterine leiomyoma pathogenesis via neuronal processes, synapsis components, proliferation, and Wnt/beta-catenin and TGF-beta pathways.

Carbajo-García MC; (...); Ferrero, Hortensia

Article. 10.1186/s12958-023-01060-2. 2023

Histone deacetylase inhibition by suberoylanilide hydroxamic acid: a therapeutic approach to treat human uterine leiomyoma.

Carbajo-Garcia, Maria Cristina; (...); Ferrero, Hortensia

Article. 10.1016/j.fertnstert.2021.10.012. 2022

Human Adenomyosis Endometrial Organoids Recapitulate Disease Pathological Features and Show Dysregulated Expression of Implantation and Placentation Biomarkers

Juarez-Barber, Elena; (...); Ferrero, Hortensia

Meeting Abstract. 2022

Human blastocysts uptake extracellular vesicles secreted by endometrial cells containing miRNAs related to implantation.

Segura-Benítez M; (...); Ferrero H

Article. 10.1093/humrep/dead138. 2023

HUMAN BLASTOCYSTS UPTAKE EXTRACELLULAR VESICLES SECRETED BY PRIMARY ENDOMETRIAL EPITHELIAL CELLS CONTAINING MIRNAS RELATED TO IMPLANTATION AND EARLY EMBRYO DEVELOPMENT

Segura-Benitez, Marina; (...); Ferrero, Hortensia

Meeting Abstract. 2022

Human endometrial organoids embedded in hybrid endometrial-derived hydrogels as a biocompatible treatment for endometrial pathologies in preclinical models

Gomez-Alvarez, M.; (...); Cervello, I.

Meeting Abstract. https://doi.org/10.1093/humrep/deae108.1104. 2024

Human Platelet-Rich Plasma from Adult Peripheral and Umbilical Cord Blood: Endometrial Regeneration and Proteomic Profiles in a Murine Model of Asherman Syndrome.

de Miguel-Gomez, L; (...); Cervello, I

Meeting Abstract. 2020

Human umbilical cord platelet-rich plasma to treat endometrial pathologies: methodology, composition and pre-clinical models.

Article. 10.1093/hropen/hoac053. 2023

Human Umbilical Cord Platelet-Rich Plasma: Metabolomic, Proteomic, and Wound Healing Studies in Endometrial Stem Cells.

Bueno-Fernandez, Clara; (...); Cervello, Irene

Meeting Abstract. 2024

Human Umbilical Cord-Based Therapeutics: Stem Cells and Blood Derivatives for Female Reproductive Medicine

Review. 10.3390/ijms232415942. 2022

Hybrid Endometrial-Derived Hydrogels: Human Organoid Culture Models and In Vivo Perspectives.

Gomez-alvarez, Maria; (...); Cervello, Irene

Article. 10.1002/adhm.202303838. 2023

Improved Models of Human Endometrial Organoids Based on Hydrogels from Decellularized Endometrium

Article. 10.3390/jpm11060504. 2021

In Pursuit of the Optimal Hydrogel for Follicle Culture: An In-depth Comparison of Ovarian Decellularization Protocols.

Campo, H; (...); Cervello, I

Meeting Abstract. 2020

Inhibition of cell proliferation and extracellular matrix formation in human uterine leiomyomas by 5-aza-2 '-deoxycitidine via Wnt/beta-catenin pathway

Carbajo-Garcia, MC; (...); Ferrero, H

Meeting Abstract. 2021

Microphysiological Modeling of the Human Endometrium

Campo H; (...); Kim JJ

Article. 10.1089/ten.tea.2020.0022. 2020

MITOPHAGY-REGULATING GENE PARKIN IS REQUIRED FOR FEMALE FERTILITY

Eguren, Adolfo Rodriguez; (...); Seli, Emre

Meeting Abstract. 2023

Murine Oocyte Maturation and Developmental Competence Using Biocompatible Hydrogel Based on Decellularized Bovine Ovarian Cortex

Lopez, Rosalba; (...); Cervello, Irene

Meeting Abstract. 2022

New insights for fertility preservation by ovarian tissue cryopreservation and transplantation in pediatric cancer patients.

Herraiz S, Cervelló I

Editorial Material. 10.1016/j.fertnstert.2020.07.057. 2020

Next Generation of Human Endometrial Organoids: Bioengineering-Based Strategies for Preserving Tissue-Specific Extracellular Environment.

Frances-Herrero, E; (...); Cervello, I

Meeting Abstract. 2021

Oviductal extracellular matrix hydrogels enhance in vitro culture of rabbit embryos and reduce deficiencies during assisted reproductive technologies

Diaz-Gimeno, P, Cervello, I

Article. 10.1038/s41598-024-77583-4. 2024

Personalized medicine through three-dimensional cell-based culture systems in assisted reproductive technologies: How close are we?

Editorial Material. 10.1016/j.fertnstert.2020.07.021. 2020

Predicted COVID-19 molecular effects on endometrium reveal key dysregulated genes and functions

Henarejos-Castillo, I; (...); Diaz-Gimeno, P.

Article. 10.1093/molehr/gaac035. 2022

Proteomic Analysis of Extracellular Vesicles Secreted by Primary Endometrial Epithelial Cells from Fertile Women Reveals Functions Related to Embryo Implantation Not Present in an Endometrial Epithelial Cell Line.

Segura-Benitez, M; (...); Ferrero, H

Meeting Abstract. 2021

Proteomic analysis of extracellular vesicles secreted by primary human epithelial endometrial cells reveals key proteins related to embryo implantation.

Segura-Benitez, Marina; (...); Ferrero, Hortensia

Article. 10.1186/s12958-021-00879-x. 2022

Role of Endometrial Extracellular Vesicles miRNAs as Potential Autocrine Regulators of Gene Expression During Embryo Implantation Process in Adenomyosis.

Meeting Abstract. 2024

Standard-dose Vitamin D supplementation as an effective and safe non-hormonal treatment for the prevention of uterine fibroid growth in reproductive-age women: A pilot study

Orive, A.; (...); Ferrero, H.

Meeting Abstract. 2023

Stem cell secreted factor therapy regenerates the ovarian niche and rescues follicles.

Buigues, Anna; (...); Herraiz, Sonia

Article. 10.1016/j.ajog.2021.01.023. 2021

Stem Cells and the Endometrium: From the Discovery of Adult Stem Cells to Pre-Clinical Models

de Miguel-Gómez L; (...); Cervelló I

Review. 10.3390/cells10030595. 2021

Strategies for managing asherman's syndrome and endometrial atrophy: Since the classical experimental models to the new bioengineering approach

de Miguel-Gómez L; (...); Cervelló I

Review. 10.1002/mrd.23523. 2021

The Effects of Platelet-Rich Plasma Derived from Human Umbilical Cord Blood in Human Endometrial Organoids

Gomez-Alvarez, Maria; (...); Cervello, Irene

Meeting Abstract. 2023

Towards the Development of the Bioengineered Ovary: Comparative Proteomic Analysis of Different Extracellular Matrix Hydrogels.

Campo, H; (...); Cervello, I

Meeting Abstract. 2021

Transcriptome analysis of adenomyosis eutopic endometrium reveals molecular mechanisms involved in adenomyosis-related implantation failure and pregnancy disorders.

Article. 10.1186/s12958-023-01182-7. 2024

Transcriptomic Analysis of Adenomyosis Mid-Secretory Endometrial Organoids Reveals Deregulated Molecular Mechanisms Involved in Implantation Failure and Pregnancy Loss