Portal de investigación
Análisis metabolómico de muestras clínicas para indentificar biomarcadores de respuesta y mecanismos de resistencia adquirida a las nuevas terapias
Datos básicos
- Código:
- ACIF/2019/003
- Protocolo:
- ACIF/2019/003
- EUDRACT:
- NCT:
- Centro:
- HOSPITAL UNIVERSITARI I POLITÈCNIC LA FE
- Dotación:
- 72.743,00 €
- Año de incio:
- 2019
- Año de finalización:
- 2022
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway.
Ghergurovich JM; (...); Rabinowitz JD
Article. 10.1038/s41589-020-0533-x. 2020
Baseline circulating myeloid-derived suppressor cells correlate with neutrophil-to-lymphocyte ratio and overall survival in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors
Garcia-Sanchez, J.; (...); Lahoz, A.
Meeting Abstract. 2021
Baseline circulating myeloid-derived suppressor cells subpopulations, neutrophils/lymphocytes ratio, and response to PD-1/PD-L1 inhibitor in non-small cell lung cancer patients.
SAnchez, JosE GarcIa; (...); Lahoz, Agustin
Meeting Abstract. 2020
Calorie restriction improves metabolic state independently of gut microbiome composition: a randomized dietary intervention trial.
Sowah, Solomon A.; (...); Zeller, Georg
Article. 10.1186/s13073-022-01030-0. 2022
c-MYC Triggers Lipid Remodelling During Early Somatic Cell Reprogramming to Pluripotency
Prieto, Javier; (...); Torres, Josema
Article. 10.1007/s12015-021-10239-2. 2021
Chemokine Receptor CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC
Becker, J; (...); Shimamura, T
Meeting Abstract. 10.1016/j.jtho.2019.08.1478. 2019
Endothelin-1-Mediated Drug Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma
Pulido, I; (...); Shimamura, T
Article. 10.1158/0008-5472.CAN-20-0141. 2020
Glutamine/glutamate metabolism rewiring in reprogrammed human hepatocyte-like cells
Ballester, M; (...); Bort, R
Article. 10.1038/s41598-019-54357-x. 2019
Identification of a Novel Synthetic Lethal Vulnerability in Non-Small Cell Lung Cancer by Co-Targeting TMPRSS4 and DDR1
Redin, E; (...); Calvo, A
Meeting Abstract. 10.1016/j.jtho.2019.08.1485. 2019
Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1
Villalba, Maria; (...); Calvo, Alfonso
Article. 10.1038/s41598-019-51066-3. 2019
LipidMS 3.0: an R-package and a web-based tool for LC-MS/MS data processing and lipid annotation.
Alcoriza-Balaguer MI; (...); Lahoz, Agustin
Article. 10.1093/bioinformatics/btac581. 2022
Methods for analysis of specific DNA methylation status.
Pajares MJ; (...); Sandoval J
Article. 10.1016/j.ymeth.2020.06.021. 2020
Mild Muscle Mitochondrial Fusion Distress Extends Drosophila Lifespan through an Early and Systemic Metabolome Reorganization.
Tapia A; (...); Galindo MI
Article. 10.3390/ijms222212133. 2021
Non-Invasive Infections Diagnosis in Lung Transplant Recipients in Exhaled Breath Condensate
Ibanez-Martinez, E.; (...); Sole-Jover, A.
Meeting Abstract. 2021
PLEIOTROPIC EFFECT OF MIR-146A CAUSES PLATELET HYPERREACTIVITY AND THROMBOSIS THROUGH METABOLIC ICA REPROGRAMMING
Sonia, Aguila; (...); Constantino, Martinez
Meeting Abstract. 2021
Pre-diagnostic alterations in circulating bile acid profiles in the development of hepatocellular carcinoma.
Stepien, Magdalena; (...); Jenab, Mazda
Article. 10.1002/ijc.33885. 2022
Reviewing the metabolome coverage provided by LC-MS: Focus on sample preparation and chromatography-A tutorial
Review. 2021
Reviewing the metabolome coverage provided by LC-MS: Focus on sample preparation and chromatography-A tutorial.
Article. 10.1016/j.aca.2020.12.025. 2021
The Potential Role of Efficacy and Safety Evaluation of N-Acetylcysteine Administration During Liver Procurement. The NAC-400 Single Center Randomized Controlled Trial
Gomez-Gavara, C; (...); Lopez-Andujar, R
Article. 10.1097/TP.0000000000003487. 2021
Translation of a tissue epigenetic signature to circulating free DNA suggests BCAT1 as a potential noninvasive diagnostic biomarker for lung cancer
Palanca-Ballester, Cora; (...); Sandoval, Juan
Article. 10.1186/s13148-022-01334-3. 2022
Tumor Microenvironment-Derived Metabolites: A Guide to Find New Metabolic Therapeutic Targets and Biomarkers
Review. 10.3390/cancers13133230. 2021