Portal de investigación
Desarrollo de un kit epigenético para el diagnóstico no invasivo para el cáncer de pulmón.
Datos básicos
- Protocolo:
- APOTIP/2019/A/004
- EUDRACT:
- NCT:
- Centro:
- Año de incio:
- 2019
- Año de finalización:
- 2021
Objetivos del proyecto
NO FAVORABLE
Documentos
- No hay documentos
Participantes
Financiadores - Promotores
Resultados del Ensayo Clínico
A novel DNA methylation-based approach for molecular subtyping and improved prognostication of colorectal cancer using formalin-fixed and paraffin-embedded tissue
Mattesen, TB; (...); Bramsen, JB
Meeting Abstract. 10.1158/1538-7445.AM2019-466. 2019
Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion
Athie, A; (...); Huarte, M
Article. 10.1083/jcb.201908078. 2020
Basic Science and Pathogenesis.
Comas-Alberti, Aina; (...); Antonell, Anna
Article. 10.1002/alz.088732. 2024
Cancer Epigenetic Biomarkers in Liquid Biopsy for High Incidence Malignancies
Palanca-Ballester, Cora; (...); Calvo, Alfonso
Article. 10.3390/cancers13123016. 2021
Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic neoplasm in mice
Garcia-Ruiz C; (...); Sanjuan-Pla A
Article. 10.1038/s41375-022-01674-2. 2022
Disruption of NIPBL/Scc2 in Cornelia de Lange Syndrome provokes cohesin genome-wide redistribution with an impact in the transcriptome
Garcia, P; (...); Queralt, E
Article. 10.1038/s41467-021-24808-z. 2021
Epigenetic and sex differences in opioid use disorder in chronic pain: A real-world study linked with OPRM1 DNA methylation.
Agullo, Laura; (...); Peiro, Ana M.
Article. 10.1111/adb.13422. 2024
Epigenetic characterization of the inflammatory hidradenitis suppurativa phenotype
Martorell, Antonio; (...); Sandoval, Juan
Meeting Abstract. 2023
Epigenetic Regulation of microRNAs in Cancer: Shortening the Distance from Bench to Bedside
Pajares MJ; (...); Sandoval J
Review. 10.3390/ijms22147350. 2021
Epigenetic Silencing of Tumor Suppressor miR-124 Directly Supports STAT3 Activation in Cutaneous T-Cell Lymphoma.
García-Colmenero L; (...); Gallardo F
Article. 10.3390/cells9122692. 2020
Epigenetics of Inflammatory Bowel Disease: Unraveling Pathogenic Events
Mateos, Beatriz; (...); Sandoval, Juan
Review. 10.1093/crocol/otz017. 2019
G9a/DNMT1 co-targeting inhibits non-small cell lung cancer growth and reprograms tumor cells to respond to cancer-drugs through SCARA5 and AOX1.
Exposito, Francisco; (...); Calvo, Alfonso
Article. 10.1038/s41419-024-07156-w. 2024
Genome wide DNA methylation profiling identifies specific epigenetic features in high-risk cutaneous squamous cell carcinoma.
Hervás-Marín D; (...); Sandoval J
Article. 10.1371/journal.pone.0223341. 2019
Genome-Wide DNA Methylation in Early-Onset-Dementia Patients Brain Tissue and Lymphoblastoid Cell Lines.
Ramos-Campoy, Oscar; (...); Antonell, Anna
Article. 10.3390/ijms25105445. 2024
Genome-wide DNA methylation profiling in anorexia nervosa discordant identical twins.
Iranzo-Tatay, C.; (...); Rojo-Moreno, L.
Article. 10.1038/s41398-021-01776-y. 2022
Identification of a Novel Synthetic Lethal Vulnerability in Non-Small Cell Lung Cancer by Co-Targeting TMPRSS4 and DDR1
Redin, E; (...); Calvo, A
Meeting Abstract. 10.1016/j.jtho.2019.08.1485. 2019
Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1
Villalba, Maria; (...); Calvo, Alfonso
Article. 10.1038/s41598-019-51066-3. 2019
Identification of Epigenetic Methylation Signatures With Clinical Value in Crohn's Disease.
Moret-Tatay I; (...); Beltrán B
Article. 10.14309/ctg.0000000000000083. 2019
Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance
Boughanem, Hatim; (...); Macias-Gonzalez, Manuel
Article. 10.1186/s12967-024-05329-x. 2024
Integrative and comparative genomic analyses identify clinicallyrelevant pulmonary carcinoidgroups and unveil the supra-carcinoids.
Alcala N; (...); Fernandez-Cuesta L
Article. 10.1038/s41467-019-11276-9. 2019
MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer
Mattesen, TB; (...); Bramsen, JB
Article. 10.1038/s41467-020-16000-6. 2020
Methods for analysis of specific DNA methylation status.
Pajares MJ; (...); Sandoval J
Article. 10.1016/j.ymeth.2020.06.021. 2020
Oral cancers preceded by Proliferative Verrucous Leukoplakia exhibit distinctive molecular features.
Herreros-Pomares A; (...); Bagan J
Article. 10.1111/odi.14550. 2023
Oxidative Stress in the Pathogenesis of Crohn's Disease and the Interconnection with Immunological Response, Microbiota, External Environmental Factors, and Epigenetics
Alemany-Cosme, E; (...); Beltran, B
Review. 10.3390/antiox10010064. 2021
Publisher Correction: MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer.
Mattesen TB; (...); Bramsen JB
Correction. 10.1038/s41467-020-16538-5. 2020
Reduced Levels of miR-145-3p Drive Cell Cycle Progression in Advanced High-Grade Serous Ovarian Cancer
Gonzalez-Canto, Eva; (...); Mari-Alexandre, Josep
Article. 10.3390/cells13221904. 2024
Sex Differences in Opioid Response Linked to OPRM1 and COMT genes DNA Methylation/Genotypes Changes in Patients with Chronic Pain.
Agullo, Laura; (...); Peiro, Ana M.
Article. 10.3390/jcm12103449. 2023
Translation of a tissue epigenetic signature to circulating free DNA suggests BCAT1 as a potential noninvasive diagnostic biomarker for lung cancer
Palanca-Ballester, Cora; (...); Sandoval, Juan
Article. 10.1186/s13148-022-01334-3. 2022
ZNF577 Methylation Levels in Leukocytes From Women With Breast Cancer Is Modulated by Adiposity, Menopausal State, and the Mediterranean Diet
Lorenzo, PM; (...); Crujeiras, AB
Article. 10.3389/fendo.2020.00245. 2020