In vivo models to approach functional genomics in myelodysplasic syndromes.

Datos básicos

Código:
2018_0246_CRC_AECC_GARCIA
Protocolo:
2018_0246_CRC_AECC_GARCIA
EUDRACT:
NCT:
Centro:
Dotación:
80.000,00 €
Año de incio:
2018
Año de finalización:
2022
RRHH NACIONAL Finan. Competitiva Privada

Objetivos del proyecto

AYUDAS PREDOCTORALES JUNTA PROVINCIAL VALENCIA

Documentos

  • No hay documentos

Participantes

Grupos

Financiadores - Promotores

FUNDACIÓN CIENTÍFICA AECC

Resultados del Ensayo Clínico


A case of megaloblastic anemia simulating a cold autoimmune hemolytic anemia.

De La Puerta R; (...); Solves P

Article. 2020


A predictive algorithm using clinical and laboratory parameters may assist in ruling out and in diagnosing MDS

Oster, HS; (...); Mittelman, M

Article. 10.1182/bloodadvances.2020004055. 2021

  • Open Access.

A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study

Maggioni, Giulia; (...); Della Porta, Matteo G.

Article. 10.1016/S2352-3026(22)00323-4. 2023

  • Open Access.

A Single-Run Next-Generation Sequencing (NGS) Assay for the Simultaneous Detection of Both Gene Mutations and Large Chromosomal Abnormalities in Patients with Myelodysplastic Syndromes (MDS) and Related Myeloid Neoplasms

Liquori, A; (...); Cervera, J

Article. 10.3390/cancers13081947. 2021

  • Open Access.

A STEP TOWARDS IDENTIFICATION AND CAUSAL INTERPRETATION OF THERAPY-RELATED MDS (T-MDS)

Kuendgen, A.; (...); Sanz, G.

Meeting Abstract. 10.1016/j.leukres.2023.107226. 2023


Aberrant Alternative Splicing in U2af1/Tet2 Double Mutant Mice Contributes to Major Hematological Phenotypes

Martínez-Valiente C; (...); Sanjuan-Pla A

Article. 10.3390/ijms22136963. 2021

  • Open Access.

Abnl Marro: An International Cooperative Trial for Patients with MDS/MPN Overlap Syndromes

Savona, Michael R.; (...); Solary, Eric

Meeting Abstract. 10.1182/blood-2019-130722. 2019

  • Open Access.

ACCELERATED FAILURE TIME MODELS AS A CLINICALLY PLAUSIBLE WAY TO DESCRIBE SURVIVAL IN MDS - AN ANALYSIS OF THE IWG-PM DATABASE

Pfeilstoecker, M.; (...); Greenberg, P.

Meeting Abstract. 10.1016/j.leukres.2023.107230. 2023


Adoptive transfer of ex-vivo expanded SARS-CoV-2-specific Cytotoxic Lymphocytes: a viable strategy for COVID-19 immunosuppressed patients?

Guerreiro M; (...); Piñana JL

Article. 10.1111/tid.13602. 2021

  • Open Access.

An agenda to advance research in myelodysplastic syndromes: a TOP 10 priority list from the first international workshop in MDS

Stahl, Maximilian; (...); Zeidan, Amer M.

Letter. 10.1182/bloodadvances.2022008747. 2023

  • Open Access.

Analysis of SNP Array Abnormalities in Patients with DE NOVO Acute Myeloid Leukemia with Normal Karyotype

Ibanez, M; (...); Cervera, J

Article. 10.1038/s41598-020-61589-9. 2020

  • Open Access.

Anti-tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL-302 in neuroblastoma

Mohlin, S; (...); Bexell, D

Article. 10.15252/emmm.201810058. 2019

  • Open Access.

Author Correction: Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes.

Bernard E; (...); Papaemmanuil E

Correction. 10.1038/s41591-021-01253-5. 2021

  • Open Access.

Building a Healthcare Alliance for Resourceful Medicine Offensive Against Neoplasms in HematologY Added Value Framework for Hematologic Malignancies: A Comparative Analysis of Existing Tools.

Cerisoli, Francesco; (...); Hernandez Rivas, Jesus Maria

Article. 10.1016/j.jval.2022.04.1729. 2022

  • Open Access.

Cause of death and excess mortality in patients with lower-risk myelodysplastic syndromes (MDS): A report from the European MDS registry.

Madry, Krzysztof; (...); Smith, Alex

Article. 10.1111/bjh.18542. 2022


Central Nervous System Involvement in Epstein-Barr Virus-Related Post-Transplant Lymphoproliferative Disorders after Allogeneic Hematopoietic Stem Cell Transplantation.

Balaguer-Rosello, Aitana; (...); Sanz, Jaime

Article. 10.1016/j.jtct.2020.12.019. 2021

  • Open Access.

Classification and Personalized Prognostic Assessment on the Basis of Clinical and Genomic Features in Myelodysplastic Syndromes.

Bersanelli M; (...); Della Porta MG

Article. 10.1200/JCO.20.01659. 2021

  • Open Access.

Classification, risk stratification and response assessment in myelodysplastic syndromes/neoplasms (MDS): A state-of-the-art report on behalf of the International Consortium for MDS (icMDS).

Stahl M; (...); Zeidan AM

Article. 10.1016/j.blre.2023.101128. 2023

  • Open Access.

Clinical and Biological Characterization of Low Risk MDS Patients According to Ring Sideroblasts (RS). Comparison between the 3 Subgroups in WHO2017 Classification. Study from the Spanish MDS Registry

Lopez Cadenas, Felix; (...); Diez-Campelo, Maria

Meeting Abstract. 10.1182/blood-2021-152678. 2021

  • Open Access.

Clinical and Genomic-Based Decision Support System to Define the Optimal Timing of Allogeneic Hematopoietic Stem-Cell Transplantation in Patients With Myelodysplastic Syndromes.

Tentori CA; (...); Della Porta MG

Article. 10.1200/JCO.23.02175. 2024

  • Open Access.

Clinical Characteristics and Transfusion Management of Patients Diagnosed of Multiple Myeloma Receiving Daratumumab: Experience of a Single Centre

Arnao, M; (...); Sanz, G

Meeting Abstract. 10.1016/j.clml.2019.09.254. 2019


Clinical Effectiveness of Influenza Vaccination After Allogeneic Hematopoietic Stem Cell Transplantation: A Cross-sectional, Prospective, Observational Study

Pinana, JL; (...); Navarro, D

Article. 10.1093/cid/ciy792. 2019

  • Open Access.

Clinical Implications of p53 Dysfunction in Patients with Myelodysplastic Syndromes

Riva, Elena; (...); Della Porta, Matteo G.

Meeting Abstract. 10.1182/blood-2022-166050. 2022

  • Open Access.

Clinical Utility of a Next-Generation Sequencing Panel for Acute Myeloid Leukemia Diagnostics

Alonso, CM; (...); Barragan, E

Article. 10.1016/j.jmoldx.2018.09.009. 2019

  • Open Access.

CLINICAL-BIOLOGICAL AND PROGNOSTIC CHARACTERISTICS OF LOW RISK SMD WITHOUT RING SIDEROBLASTS AND COMPARISON WITH ITS COUNTERPART WITH RING SIDEROBLASTS

Cadenas Felix, Lopez; (...); Ferreiras David, Valcarcel

Meeting Abstract. 2021

  • Open Access.

Community acquired respiratory virus infections in adult patients undergoing umbilical cord blood transplantation.

Montoro J; (...); Piñana JL

Article. 10.1038/s41409-020-0943-0. 2020

  • Open Access.

COMPARISON OF CYTOGENETIC ABERRATIONS IN 1590 PATIENTS WITH THERAPY-RELATED MDS (T-MDS) AND 4738 PATIENTS FROM THE REVISED INTERNATIONAL PROGNOSTIC SCORING SYSTEM DATABASE WITH PRIMARY-MDS (P-MDS)

Kuendgen, A.; (...); Sanz, G.

Meeting Abstract. 2021


COMPARISON OF THREE PANELS OF NGS APPLICATION IN ONCOHEMATOLOGY TO DISCARD SOMATIC AND/OR GERMINAL VARIANTS

Guzman-Gimenez, C.; (...); Such, E.

Meeting Abstract. 2021

  • Open Access.

Comparison of transfusion requirements in adult patients undergoing Haploidentical or single-unit umbilical cord blood stem cell transplantation

Solves, P; (...); Sanz, GF

Article. 10.1111/ejh.13270. 2019


Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic neoplasm in mice

Garcia-Ruiz C; (...); Sanjuan-Pla A

Article. 10.1038/s41375-022-01674-2. 2022

  • Open Access.

Consensus proposal for revised International Working Group response criteria for higher risk myelodysplastic syndromes.

Zeidan, Amer M.; (...); Fenaux, Pierre

Article. 10.1182/blood.2022018604. 2023

  • Open Access.

Contemporary Approach to The Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes- Recommendations from The International Consortium for MDS (icMDS).

Aakash, Fnu; (...); Loghavi, Sanam

Article. 10.1016/j.modpat.2024.100615. 2024


CO-OCCURRENCE PROFILES OF GERMLINE AND ACQUIRED VARIANTS IN MYELODYSPLASTIC SYNDROMES IN YOUNG ADULTS WITHOUT PRIOR ORGAN DYSFUNCTION

Hua, Chen-Liang Tzu; (...); Andres, Jerez

Meeting Abstract. 2021

  • Open Access.

CRISPR to fix bad blood: a new tool in basic and clinical hematology

Gonzalez-Romero, E; (...); Sanjuan-Pla, A

Review. 10.3324/haematol.2018.211359. 2019

  • Open Access.

Cross-Sectional Comparative Study of PK-Guided Switch between Standard Half-Life and Extended Half-Life Factor VIII Products

Eduardo Megias, Juan; (...); Iorio, Alfonso

Meeting Abstract. 10.1182/blood-2019-127946. 2019

  • Open Access.

Cryopreservation of Allogeneic Hematopoietic Progenitor Cells in The Current SARS-Cov-2 Pandemic: Experience of A Single Centre

Moreno, D; (...); Carpio, N

Meeting Abstract. 2021


Current landscape of translational and clinical research in myelodysplastic syndromes/neoplasms (MDS): Proceedings from the 1st International Workshop on MDS (iwMDS) Of the International Consortium for MDS (icMDS).

Bewersdorf, Jan Philipp; (...); Zeidan, Amer M.

Article. 10.1016/j.blre.2023.101072. 2023

  • Open Access.

CHARACTERIZATION OF CONGENITAL THROMBOTIC THROMBOCYTOPENIC PURPURA BY MEANS OF IMMUNOLOGICAL AND MOLECULAR TECHNIQUES: RESULTS OF THE GEPTT NATIONAL COLLECTION

Liquori, A.; (...); Gomez-Segui, I

Meeting Abstract. 2019

  • Open Access.

CHARACTERIZATION OF CHARACTERISTIC MORPHOLOGICAL ALTERATIONS IN PATIENTS WITH MDS/CMML AND GENE MUTATIONS OF SPLICING DIFFERENT TO SF3B1

Marco Ayala, J.; (...); Sanz, G.

Meeting Abstract. 2019

  • Open Access.

CHARACTERIZATION OF THE GENOMIC AND TRANSCRIPTOMIC PROFILE OF THE ACUTE MYELOID LEUKEMIA (AML) SUBGROUP "CHROMATIN-SPLICEOSOME"

Alessandro, Liquori; (...); Zamora Jose, Cervera

Meeting Abstract. 2020

  • Open Access.

Chronic graft-versus-host disease could ameliorate the impact of adverse somatic mutations in patients with myelodysplastic syndromes and hematopoietic stem cell transplantation.

Caballero JC; (...); Díez Campelo M

Article. 10.1007/s00277-019-03751-6. 2019


Data-driven, harmonised classification system for myelodysplastic syndromes: a consensus paper from the International Consortium for Myelodysplastic Syndromes.

Komrokji RS; (...); Della Porta MG

Article. 10.1016/S2352-3026(24)00251-5. 2024


Determinants of low health-related quality of life in patients with myelodysplastic syndromes: EUMDS Registry study.

Stojkov I; (...); Siebert U

Article. 10.1182/bloodadvances.2022008360. 2023

  • Open Access.

Development of a core outcome set for myelodysplastic syndromes - a Delphi study from the EUMDS Registry Group.

Rochau U; (...); Stauder R

Article. 10.1111/bjh.16654. 2020

  • Open Access.

Disease Characteristics and International Prognostic Scoring Systems (IPSS, IPSS-R, IPSS-M) in Adult Patients with Higher-Risk Myelodysplastic Syndromes (MDS) Participating in Two Randomized, Double-Blind, Placebo-Controlled Studies with Intravenous Sabatolimab Added to Hypomethylating Agents (HMA) (STIMULUS-MDS1 and MDS2)

Santini, Valeria; (...); Zeidan, Amer M.

Meeting Abstract. 10.1182/blood-2022-160282. 2022

  • Open Access.

Do next-generation sequencing results drive diagnostic and therapeutic decisions in MDS?

Sanz GF, Ibañez M, Such E

Article. 10.1182/bloodadvances.2019000680. 2019

  • Open Access.

Does RAD21 Co-Mutation Have a Role in DNMT3A Mutated AML? Results of Harmony Alliance AML Database

Azibeiro Melchor, Raul; (...); Ossenkoppele, Gert J.

Meeting Abstract. 10.1182/blood-2021-150766. 2021

  • Open Access.

Dynamics of Mortality and Transformation Risk within Different Risk Groups of Patients with Myelodysplastic Syndromes Stratified According to the IPSS-R - Comparison of Treated and Untreated Patients and Consequences for the Description of Risk Categories

Pfeilstocker, Michael; (...); Greenberg, Peter L.

Meeting Abstract. 10.1182/blood-2022-158671. 2022

  • Open Access.

EFFECT OF MISSENSE MUTATIONS IN THE SPLICING OF PATIENTS WITH ACUTE MYELOID LEUKAEMIA

Morote-Faubel, M.; (...); Cervera, J.

Meeting Abstract. 2019

  • Open Access.

EFFECTIVENESS AND SAFETY OF THE INFUSION OF DONOR LYMPHOCYTES AFTER HAPLOIDENTICAL TRANSPLANTATION OF HEMATOPOYETIC PROGENITOR CELLS WITH POST-TRANSPLANT CYCLOPHOSPHAMIDE: MULTICENTRIC RETROSPECTIVE STUDY OF THE HEMATOPETIC SPANISH TRIPASHOLE GROUP

Martin-Sanchez, Guillermo; (...); Bermudez, Aranzazu

Meeting Abstract. 2020

  • Open Access.

Effects of the Therapeutic Armamentarium on Survival and Time to Next Treatment in CMML Subtypes: An International Analysis of 950 Cases Coordinated By the AGMT Study Group

Pleyer, Lisa; (...); Greil, Richard

Meeting Abstract. 10.1182/blood-2019-123941. 2019

  • Open Access.

Enhancing Cytogenetic Diagnostics: Incorporating Optical Genome Mapping in the Laboratory Routine

Diaz-Gonzalez, Alvaro; (...); Such, Esperanza

Meeting Abstract. 10.1182/blood-2023-180691. 2023

  • Open Access.

Epidemiology of Hereditary Thrombotic Thrombocytopenic Purpura (TTP) in Spain: Preliminary Results of a Study of the Spanish TTP Registry (REPTT)

Segui, Ines Gomez; (...); Garma, Julio Del Rio

Meeting Abstract. 2024


Evaluation of Lenalidomide (LEN) Vs Placebo in Non-Transfusion Dependent Low Risk Del(5q) MDS Patients. Final Results of Sintra-REV Phase III International Multicenter Clinical Trial

Lopez Cadenas, Felix; (...); Diez-Campelo, Maria

Meeting Abstract. 10.1182/blood-2022-168718. 2022

  • Open Access.

Finding consistency in classifications of myeloid neoplasms: a perspective on behalf of the International Workshop for Myelodysplastic Syndromes.

Zeidan, Amer M.; (...); Santini, Valeria

Article. 10.1038/s41375-022-01724-9. 2022

  • Open Access.

FUNCTIONAL RECLASSIFICATION THROUGH MINIGENE TESTS OF MISSENSE VARIANTS WITH EFFECT ON SPLICING IN PATIENTS WITH ACUTE MYELOID LEUKEMIA

Morote-Faubel, Mireya; (...); Cervera, Jose

Meeting Abstract. 2020

  • Open Access.

Generation of Multimodal Longitudinal Synthetic Data By Artificial Intelligence to Improve Personalized Medicine in Hematology

D'Amico, Saverio; (...); Della Porta, Matteo Giovanni

Meeting Abstract. 10.1182/blood-2024-209541. 2024


GENOMIC CLASSIFICATION OF MYELODYSPLASTIC SYNDROMES

Bernard, E.; (...); Papaemmanuil, E.

Meeting Abstract. 10.1016/j.leukres.2023.107146. 2023


Guadecitabine vs TC in relapsed/refractory AML after intensive chemotherapy: randomized phase 3 ASTRAL-2 trial.

Roboz GJ; (...); Döhner H

Article. 10.1182/bloodadvances.2023012062. 2024

  • Open Access.

Harmony Alliance Provides a Machine Learning Researching Tool to Predict the Risk of Relapse after First Remission in AML Patients Treated without Allogeneic Haematopoietic Stem Cell Transplantation

Sobas, Marta; (...); Maria Hernandez-Rivas, Jesus

Meeting Abstract. 10.1182/blood-2021-149521. 2021

  • Open Access.

Hematopoietic stem cell transplantation with unrelated cord blood or haploidentical donor grafts in adult patients with secondary acute myeloid leukemia, a comparative study from Eurocord and the ALWP EBMT.

Ruggeri A; (...); Nagler A

Article. 10.1038/s41409-019-0582-5. 2019


Immune reconstitution after single-unit umbilical cord blood transplantation using anti-thymoglobulin and myeloablative conditioning in adults with hematological malignancies.

Cordón L; (...); Sanz J

Article. 10.1007/s00277-024-05758-0. 2024


Immune Reconstitution Profiling Suggests Antiviral Protection After Transplantation with Omidubicel: a Phase 3 Substudy.

Szabolcs, Paul; (...); Horwitz, Mitchell E.

Article. 10.1016/j.jtct.2023.04.018. 2023

  • Open Access.

IMPACT OF ALLELIC STATUS OF TP53 MUTATIONS IN ACUTE MYELOID LEUKEMIA (AML)

Ibanez, Mariam; (...); Sanz, Guillermo

Meeting Abstract. 2020

  • Open Access.

Impact of Gender on Molecular AML Subclasses - a Harmony Alliance Study

Matteuzzi, Tommaso; (...); Bullinger, Lars

Meeting Abstract. 10.1182/blood-2021-152215. 2021

  • Open Access.

Impact of red blood cell transfusion dose density on progression-free survival in lower-risk myelodysplastic syndromes patients.

de Swart L; (...); EUMDS Registry Participants

Article. 10.3324/haematol.2018.212217. 2020

  • Open Access.

IMPACT OF THE TREATMENT OF THE PURE APLASIA OF THE RED SERIES; EXPERIENCE IN A CENTER

Marco, Ayala Javier; (...); Solves, Alcaina Pilar

Meeting Abstract. 2020

  • Open Access.

Impact of treatment with iron chelation therapy in patients with lower-risk myelodysplastic syndromes participating in the European MDS registry.

Hoeks M; (...); EUMDS Registry Participants

Article. 10.3324/haematol.2018.212332. 2020

  • Open Access.

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes (vol 26, pg 1549, 2020)

Bernard, Elsa; (...); Elias, Harold K

Article. 10.1038/s41591-021-01367-w. 2021

  • Open Access.

Implications ofTP53allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Bernard, E; (...); Papaemmanuil, E

Article. 10.1038/s41591-020-1008-z. 2020

  • Open Access.

In MDS, is higher risk higher reward?

Sanz GF

Article. 10.1182/hematology.2019000042. 2019

  • Open Access.

IN VIVO MODELS TO STUDY THE COOPERATION BETWEEN SPLICING AND DNA METHYLATION IN MYELODYSPLASTIC SYNDROMES

Martinez-Valiente, Cristina; (...); Sanjuan-Pla, Alejandra

Meeting Abstract. 2020

  • Open Access.

Incidence and outcome of invasive fungal disease after front-line intensive chemotherapy in patients with acute myeloid leukemia: impact of antifungal prophylaxis.

Rodríguez-Veiga R; (...); Sanz GF

Article. 10.1007/s00277-019-03744-5. 2019


Incidence and prognostic impact of U2AF1 mutations and other gene alterations in myelodysplastic neoplasms with isolated 20q deletion.

Castillo MI; (...); Díaz TM

Article. 10.1002/cam4.6300. 2023

  • Open Access.

Incidence, Clinical Associations, and Co-Mutation Patterns of UBA1 Mutations in MDS

Sirenko, Maria; (...); Papaemmanuil, Elli

Meeting Abstract. 10.1182/blood-2022-162397. 2022

  • Open Access.

Incidence, risk factors, and outcome of pulmonary invasive fungal disease after respiratory virus infection in allogeneic hematopoietic stem cell transplantation recipients

Pinana, JL; (...); Navarro, D

Article. 10.1111/tid.13158. 2019

  • Open Access.

IN-SILICO AND IN VITRO STUDY OF MUTATIONS THAT ALTER THE SPLICING PROCESS IN PATIENTS WITH MYELODISPLASIC SYNDROMES

Boluda-Navarro, M.; (...); Cervera, J.

Meeting Abstract. 2019

  • Open Access.

Invasive fungal disease in patients undergoing umbilical cord blood transplantation after myeloablative conditioning regimen

Montoro, J; (...); Pinana, JL

Article. 10.1111/ejh.13202. 2019


LAG3 genotype of the donor and clinical outcome after allogeneic transplantation from HLA-identical sibling donors.

Cruz, David; (...); Gallardo, David

Article. 10.3389/fimmu.2023.1066393. 2023

  • Open Access.

Longitudinal outcomes of obeticholic acid therapy in ursodiol-nonresponsive primary biliary cholangitis: Stratifying the impact of add-on fibrates in real-world practice.

Gomez, E; (...); Fernandez-Rodriguez, C M

Article. 10.1111/apt.18004. 2024

  • Open Access.

Long-term prospective results of the Spanish multicentre experience using recirculant hyperthermic MMC with Combat BRS HIVEC system

Guerrero-Ramos, F.; (...); Angulo-Cuesta, J.

Meeting Abstract. 2022


Lymphoid and myeloid immune cell reconstitution after nicotinamide-expanded cord blood transplantation

de Koning, Coco; (...); Nierkens, Stefan

Article. 10.1038/s41409-021-01417-4. 2021

  • Open Access.

LYMPHOPENIA IS HIGHLY PREVALENT IN MDS AND PROVIDES ADDITIONAL PROGNOSTIC INFORMATION FOR IPSS-R VERY-LOW AND LOW-RISK PATIENTS. AN ANALYSIS FROM THE EU-MDS REGISTRY

Silzle, T.; (...); Smith, A.

Meeting Abstract. 2021


Lymphopenia is highly prevalent in MDS and provides prognostic information for IPSS-R (very)-low-risk patients. An analysis from the EU-MDS registry

Silzle, T.; (...); Smith, A.

Meeting Abstract. 2021


Machine Learning Allows the Identification of New Co-Mutational Patterns with Prognostic Implications in NPM1 Mutated AML - Results of the European Harmony Alliance

Hernandez Sanchez, Alberto; (...); Bullinger, Lars

Meeting Abstract. 10.1182/blood-2022-167138. 2022

  • Open Access.

Machine Learning Provides Individualized Prediction of Outcomes after First Complete Remission in Adult AML Patients - Results from the Harmony Platform

Hernandez Sanchez, Alberto; (...); Bullinger, Lars

Meeting Abstract. 10.1182/blood-2023-183029. 2023


Management of adult patients with CMML undergoing allo-HCT: recommendations from the EBMT PH&G Committee.

Onida F; (...); Pleyer L

Article. 10.1182/blood.2023023476. 2024

  • Open Access.

Management of MDS with Isolated Del(5q) Patients in the European MDS (EUMDS) Registry, a Unique Prospective Real-World Dataset

Bowen, David; (...); de Witte, Theo M.

Meeting Abstract. 10.1182/blood-2021-150322. 2021

  • Open Access.

Management of MDS with Isolated Del(5q) Patients in the European MDS (EUMDS) Registry: A Report on 197 Cases

Smoljanovic, Inga Mandac; (...); Bowen, David

Meeting Abstract. 10.1182/blood-2022-167716. 2022


Managing hematological cancer patients during the COVID-19 pandemic: an ESMO-EHA Interdisciplinary Expert Consensus.

Buske C; (...); Passamonti F

Article. 10.1016/j.esmoop.2022.100403. 2022

  • Open Access.

MASS SEQUENCING DIRECTED TO THE STUDY OF REARRANGEMENTS AND CHANGES IN GENIC EXPRESSION IN ACUTE MYELOID LEUKEMIA

Sargas Simarro, C.; (...); Barragan Gonzalez, E.

Meeting Abstract. 2019

  • Open Access.

MODELING OF IDH2 GENE MUTATIONS IN THE CAENORHABDITIS ELEGANS ORGANISM. DEVELOPMENT OF A NEW STUDY MODEL

Gonzalez-Romero, E.; (...); Cervera-Zamora, J.

Meeting Abstract. 2021

  • Open Access.

Molecular and clinical presentation of UBA1-mutated myelodysplastic syndromes.

Sirenko, Maria; (...); Papaemmanuil, Elli

Article. 10.1182/blood.2023023723. 2024


MOLECULAR CHARACTERIZATION OF VARIANTS THAT ALTER SPLICING (VAS) IN PATIENTS WITH MYELODYSPLASIC SYNDROMES

Boluda-Navarro, M.; (...); Cervera, J.

Meeting Abstract. 2020

  • Open Access.

Molecular Taxonomy of Myelodysplastic Syndromes and Its Clinical Implications

Bernard, Elsa; (...); Papaemmanuil, Elli

Meeting Abstract. 10.1182/blood-2023-186863. 2023

  • Open Access.

Molecular Taxonomy of Myelodysplastic Syndromes and its Clinical Implications.

Bernard, Elsa; (...); Papaemmanuil, Elli

Article. 10.1182/blood.2023023727. 2024


Multicenter Long-Term Follow-Up of Allogeneic Hematopoietic Cell Transplantation with Omidubicel: A Pooled Analysis of Five Prospective Clinical Trials.

Lin, Chenyu; (...); Horwitz, Mitchell E.

Article. 10.1016/j.jtct.2023.01.031. 2023

  • Open Access.

Myelodysplastic syndromes with 20q deletion: incidence, prognostic value and impact on response to azacitidine of ASXL1 chromosomal deletion and genetic mutations

Martin, I; (...); Tormo, M

Article. 10.1111/bjh.17675. 2021


Myelodysplastic syndromes: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Fenaux, P; (...); ESMO Guidelines Comm

Article. 10.1016/j.annonc.2020.11.002. 2021

  • Open Access.

National Survey on the Use of Mobile Applications in Patients with Hemophilia and Other Coagulopathies

Eduardo Megias, Juan; (...); Poveda Andres, Jose Luis

Meeting Abstract. 10.1182/blood-2022-169938. 2022

  • Open Access.

Noninfectious Neurologic Complications after Allogeneic Hematopoietic Stem Cell Transplantation

Balaguer-Rosello, A; (...); Sanz, Jaime

Article. 10.1016/j.bbmt.2019.05.024. 2019

  • Open Access.

Non-infectious neurologic complications after allogeneic hematopoietic stem cell transplantation (ALLO-HSCT)

Balaguer Rosello, Aitana; (...); Sanz, Jaime

Meeting Abstract. 2019


Novel dynamic outcome indicators and clinical endpoints in myelodysplastic syndrome; the European LeukemiaNet MDS Registry and MDS-RIGHT project perspective.

De Witte T; (...); Smith A

Article. 10.3324/haematol.2020.266817. 2020

  • Open Access.

Omidubicel vs standard myeloablative umbilical cord blood transplantation: results of a phase 3 randomized study.

Horwitz, ME; (...); Sanz, G

Article. 10.1182/blood.2021011719. 2021

  • Open Access.

OPTIMIZATION OF THE EFFICIENCY OF GENETIC EDITING OF HEMAPOYETIC PROGENITOR CELLS USING CRISPR/CAS9 RIBONUCLEOPROTEINS

Martinez-Valiente, C.; (...); Sanjuan-Pla, A.

Meeting Abstract. 2019

  • Open Access.

Outcome of lower-risk myelodysplastic syndrome with ring sideroblasts (MDS-RS) after failure of erythropoiesis- stimulating agents

Park, Sophie; (...); Fenaux, Pierre

Letter. 10.1016/j.leukres.2020.106472. 2020


Outcomes and effect of somatic mutations after erythropoiesis stimulating agents in patients with lower-risk myelodysplastic syndromes.

Caballero, Juan Carlos; (...); Diez Campelo, Maria

Article. 10.1177/20406207231218157. 2024

  • Open Access.

Panel Sequencing for Clinically Oriented Variant Screening and Copy Number Detection in Chronic Lymphocytic Leukemia Patients

Ibanez, Mariam; (...); Luna I

Article. 10.3390/diagnostics12040953. 2022

  • Open Access.

PAN-STAKEHOLDER CORE OUTCOME SET (COS) DEFINITION FOR HEMATOLOGICAL MALIGNANCIES IN THE FRAMEWORK OF THE EU PROJECT, HARMONY: THE HEALTHCARE ALLIANCE FOR RESOURCEFUL MEDICINE OFFENSIVE AGAINST NEOPLASMS IN HEMATOLOGY

Lang, K.; (...); Bullinger, L.

Meeting Abstract. 2023


Pan-Stakeholder Core Outcome Set (COS) Definition for Hematological Malignancies within the Framework of Harmony and Harmony PLUS Projects

Lang, Katharina M.; (...); Bullinger, Lars

Meeting Abstract. 10.1182/blood-2022-157549. 2022

  • Open Access.

Pan-Stakeholder Core Outcome Set (COS) Definition for Selected Hematological Malignancies - Results of the Harmony Alliance

Lang, Katharina M.; (...); Bullinger, Lars

Meeting Abstract. 10.1182/blood-2021-145002. 2021

  • Open Access.

Partial T Cell-Depleted Peripheral Blood Stem Cell Transplantation from HLA-Identical Sibling Donors for Patients with Severe Aplastic Anemia.

Sanz J; (...); Piñana JL

Article. 10.1016/j.bbmt.2019.08.020. 2020

  • Open Access.

PCR-Based Strategy for Introducing CRISPR/Cas9 Machinery into Hematopoietic Cell Lines.

González-Romero E; (...); Vázquez-Manrique RP

Article. 10.3390/cancers15174263. 2023

  • Open Access.

Phase I trials of the lysine-specific demethylase 1 inhibitor, GSK2879552, as mono- and combination-therapy in relapsed/refractory acute myeloid leukemia or high-risk myelodysplastic syndromes.

Roboz, Gail J.; (...); Wei, Andrew H.

Letter. 10.1080/10428194.2021.2012667. 2022

  • Open Access.

Phase I/II Study of Stem-Cell Transplantation Using a Single Cord Blood Unit Expanded Ex Vivo With Nicotinamide

Horwitz, ME; (...); Sanz, G

Article. 10.1200/JCO.18.00053. 2019

  • Open Access.

Prognostic factors for adult single cord blood transplantation among European and Japanese populations: the Eurocord/ALWP-EBMT and JSHCT/JDCHCT collaborative study.

Kanda J; (...); Gluckman E

Article. 10.1038/s41375-019-0534-5. 2020


Prospective Randomized Study Comparing Myeloablative Unrelated Umbilical Cord Blood Transplantation versus HLA-Haploidentical Related Stem Cell Transplantation for Adults with Hematologic Malignancies.

Sanz J; (...); Piñana JL

Article. 10.1016/j.bbmt.2019.10.014. 2020

  • Open Access.

Pulmonary cytomegalovirus (CMV) DNA shedding in allogeneic hematopoietic stem cell transplant recipients: Implications for the diagnosis of CMV pneumonia

Pinana, JL; (...); Navarro, D

Article. 10.1016/j.jinf.2019.02.009. 2019

  • Open Access.

Pure red cell aplasia after major or bidirectional ABO incompatible hematopoietic stem cell transplantation: to treat or not to treat, that is the question.

Marco-Ayala J; (...); Solves P

Review. 10.1038/s41409-020-01124-6. 2021


Randomized Phase 1-2 Study to Assess Safety and Efficacy of Low-Dose (LD) Oral Decitabine/ Cedazuridine (ASTX727) in Lower-Risk Myelodysplastic Syndromes (LR-MDS) Patients: Interim Safety Analysis

Garcia-Manero, Guillermo; (...); Yacoub, Abdulraheem

Meeting Abstract. 2023


RANDOMIZED PHASE 2 STUDY TO ASSESS SAFETY AND EFFICACY OF LOW-DOSE (LD) ORAL DECITABINE/CEDAZURIDINE (ASTX727) IN LOWER-RISK MYELODYSPLASTIC SYNDROMES (LR-MDS) PATIENTS: INTERIM SAFETY ANALYSIS

Garcia-Manero, G.; (...); Yacoub, A.

Meeting Abstract. 10.1016/j.leukres.2023.107270. 2023


Rapid and Robust CD4+and CD8+T-, NK-, B-Cell, Dendritic Cell, and Monocyte Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation

de Koning, Coco; (...); Boelens, Jaap-Jan

Meeting Abstract. 2019


REAL-LIFE EFFICACY OF A MULTI-INGREDIENT CORIOLUS VERSICOLOR-BASED VAGINAL GEL IN HIGH-RISK HPV PATIENTS: THE PAPILOBS STUDY FINAL RESULTS

Gaslain, Y.; (...); Sanmartin, P.

Meeting Abstract. 10.1136/ijgc-2021-ESGO.553. 2021

  • Open Access.

Real-World Validation of Molecular International Prognostic Scoring System (IPSS-M) for Myelodysplastic Syndromes

Sauta, Elisabetta; (...); Della Porta, Matteo G.

Meeting Abstract. 10.1182/blood-2022-163634. 2022

  • Open Access.

Real-World Validation of Molecular International Prognostic Scoring System for Myelodysplastic Syndromes.

Sauta, Elisabetta; (...); Della Porta, Matteo Giovanni

Article. 10.1200/JCO.22.01784. 2023

  • Open Access.

Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study.

Hernandez-Sanchez, Alberto; (...); Bullinger, Lars

Article. 10.1038/s41375-024-02333-4. 2024

  • Open Access.

Rearrangements Involving 11q23/KMT2A: Mutational Landscape and Prognostic Implications - Results of the Harmony Alliance AML Database

Hernandez Sanchez, Alberto; (...); Bullinger, Lars

Meeting Abstract. 10.1182/blood-2022-167480. 2022

  • Open Access.

REMOVAL OF GERMINAL LINE MUTATIONS IN PATIENTS WITH MDS AND AML: WHO SHOULD BE PERFORMED?

Santiago, Marta; (...); Cervera, Jose

Meeting Abstract. 2020


Response to azacitidine in patients with chronic myelomonocytic leukemia according to overlap myelodysplastic/myeloproliferative neoplasms criteria*

Triguero, A.; (...); Sanz, G.

Article. 10.1016/j.leukres.2022.106836. 2022


Results from a Global Randomized Phase 3 Study of Guadecitabine (G) Vs Treatment Choice (TC) in 302 Patients with Relapsed or Refractory (r/r) Acute Myeloid Leukemia after Intensive Chemotherapy (ASTRAL-2 Study)

Roboz, Gail J.; (...); Dohner, Hartmut

Meeting Abstract. 10.1182/blood-2021-147769. 2021

  • Open Access.

Results of two protocols for platelet transfusion in patients undergoing abo incompatible hematopoietic stem cell transplantation

Solves, P; (...); Sanz, G

Letter. 10.1016/j.transci.2019.02.002. 2019


RNA Sequencing Analysis for the Identification of a PCM1/PDGFRB Fusion Gene Responsive to Imatinib

Such, E; (...); Cervera, J

Article. 10.1159/000497348. 2019


Sabatolimab (MBG453) Combination Treatment Regimens for Patients (Pts) with Higher-Risk Myelodysplastic Syndromes (HR-MDS): The MDS Studies in the Stimulus Immuno-Myeloid Clinical Trial Program

Zeidan, Amer M.; (...); Garcia-Manero, Guillermo

Meeting Abstract. 10.1182/blood-2021-145626. 2021

  • Open Access.

Spanish Guidelines for the use of targeted deep sequencing in myelodysplastic syndromes and chronic myelomonocytic leukaemia.

Palomo L; (...); Such E

Article. 10.1111/bjh.16175. 2020

  • Open Access.

STIMULUS-MDS2 design and rationale: a phase III trial with the anti-TIM-3 sabatolimab (MBG453)+azacitidine in higher risk MDS and CMML-2.

Zeidan AM; (...); Santini V

Article. 10.2217/fon-2022-1237. 2023

  • Open Access.

STUDY OF TRANSCRIPTIONAL DIFFERENCES BETWEEN THE IDH2 R140 AND R172 MUTATIONS BY MEANS OF MODELING IN THE ORGANISM CAENORHABDITIS ELEGANS

Gonzalez, Romero Elisa; (...); Cervera, Jose Vicente

Meeting Abstract. 2020

  • Open Access.

The clinical benefit of instituting a prospective clinical community-acquired respiratory virus surveillance program in allogeneic hematopoietic stem cell transplantation.

Piñana J; (...); Sanz J

Article. 10.1016/j.jinf.2019.12.022. 2020

  • Open Access.

The effect of timing on community acquired respiratory virus infection mortality during the first year after allogeneic hematopoietic stem cell transplantation: a prospective epidemiological survey.

Piñana JL; (...); Navarro D

Article. 10.1038/s41409-019-0698-7. 2020

  • Open Access.

The impact of GVHD on outcomes after adult single cord blood transplantation in European and Japanese populations.

Kanda, Junya; (...); Gluckman, Eliane

Article. 10.1038/s41409-021-01479-4. 2022

  • Open Access.

The Impact of GVHD on Outcomes After Adult Single Cord Blood Transplantation In European And Japanese Populations: The EUROCORD/ALWP EBMT And JSHCT/JDCHCT Collaborative Study

Kanda, J; (...); Gluckman, E

Meeting Abstract. 2021


Therapy-related myelodysplastic syndromes deserve specific diagnostic sub-classification and risk-stratification-an approach to classification of patients with t-MDS.

Kuendgen A; (...); Sanz G

Article. 10.1038/s41375-020-0917-7. 2020

  • Open Access.

Towarda more patient-centered drug development process in clinical trials for patients with myelodysplastic syndromes/neoplasms (MDS): Practical considerations from the International Consortium for MDS (icMDS).

Efficace, Fabio; (...); Zeidan, Amer M

Article. 10.1002/hem3.69. 2024

  • Open Access.

TRANSCRIPTOMICAL ANALYSIS AND MODELING IN C.ELEGANS OF THE IDH2 R140 R172 MUTATION

Gonzalez-Romero, E.; (...); Cervera-Zamora, J., V

Meeting Abstract. 2019

  • Open Access.

Transfusion Burden in Allogeneic Hematopoietic Stem Cell Transplantation over Time: Experience from a Single Institution.

Solves, Pilar; (...); Sanz, Jaime

Article. 10.3390/jcm12103467. 2023

  • Open Access.

Transfusion management in multiple myeloma patients receiving daratumumab: Experience of a single tertiary care centre.

Solves P; (...); Carpio N

Article. 10.1016/j.transci.2019.09.011. 2020


Treatment Patterns and Overall Survival in Patients with Intermediate-Risk MDS: A Retrospective Analysis in the Spanish MDS Registry

Diez-Campelo, Maria; (...); Valcarcel, David

Meeting Abstract. 10.1182/blood-2021-146019. 2021

  • Open Access.

UBA1 Mutations Identify a Rare but Distinct Subtype of Myelodysplastic Syndromes

Sirenko, Maria; (...); Papaemmanuil, Elli

Meeting Abstract. 10.1182/blood-2023-182949. 2023

  • Open Access.

Uniform graft-versus-host disease prophylaxis with posttransplant cyclophosphamide, sirolimus, and mycophenolate mofetil following hematopoietic stem cell transplantation from haploidentical, matched sibling and unrelated donors.

Montoro J; (...); Sanz J

Article. 10.1038/s41409-020-0921-6. 2020


Validation of a multivariable prediction model for post-engraftment invasive fungal disease in 465 adult allogeneic hematopoietic stem cell transplant recipients

Rodriguez-Veiga, Rebeca; (...); Sanz, Miguel A.

Article. 10.1111/myc.12891. 2019


VALIDATION OF A PANEL OF GENES BY MASSIVE SEQUENCING FOR THE SCREENING OF GERMINAL MUTATIONS IN GENES ASSOCIATED WITH HEREDITARY MYELOID NEOPLASMS

Ibanez, M.; (...); Cervera, J., V

Meeting Abstract. 2019

  • Open Access.

Campos de estudio

Compartir