Portal de recerca
Estrategia híbrida basada en el cateterismo cardíaco y la conjugación polimérica del ácido docosahexanoico para la prevención del daño miocárdico inducido por reperfusión.
Dades bàsiques
- Protocol:
- APOTI/2018/018
- EURDRACT:
- NCT:
- Centre:
- Any inici:
- 2018
- Any de finalització:
- 2019
Documents
- No hi ha documents
Participants
Grups d'Investigació
Finançadors - Promotors
Resultats de l'Assaig Clínic
Conductive polycaprolactone/gelatin/polyaniline nanofibres as functional scaffolds for cardiac tissue regeneration
Gil-Castell, O.; (...); Ribes-Greus, A.
Article. 10.1016/j.reactfunctpolym.2021.105064. 2022
A Fibrosis Biomarker Early Predicts Cardiotoxicity Due to Anthracycline-Based Breast Cancer Chemotherapy
de la Fuente, Ana; (...); Ravassa, Susana
Article. 10.3390/cancers14122941. 2022
ATR-FTIR spectroscopy for the routine quality control of exosome isolations
Ramos-Garcia, V; (...); Kuligowski, J
Article. 10.1016/j.chemolab.2021.104401. 2021
Balance of Active, Passive, and Anatomical Cardiac Properties in Doxorubicin-Induced Heart Failure.
Lewalle A; (...); Niederer SA
Article. 10.1016/j.bpj.2019.07.033. 2019
Cardiopulmonary Rehabilitation Improves Respiratory Muscle Function and Functional Capacity in Children with Congenital Heart Disease. A Prospective Cohort Study
Ferrer-Sargues FJ; (...); Iranzo, MACI
Article. 10.3390/ijerph17124328. 2020
Circulating exosomes deliver free fatty acids from the bloodstream to cardiac cells: Possible role of CD36
Garcia, NA; (...); Sepulveda, P
Article. 10.1371/journal.pone.0217546. 2019
Co-administration of human MSC overexpressing HIF-1a increases human CD34(+) cell engraftment in vivo.
Preciado S; (...); Sánchez-Guijo F
Article. 10.1186/s13287-021-02669-z. 2021
Corrigendum to "Plasmatic Membrane Expression of Adhesion Molecules in Human Cardiac Progenitor/Stem Cells Might Explain Their Superior Cell Engraftment after Cell Transplantation".
Ontoria-Oviedo I; (...); Sepúlveda P
Correction. 10.1155/2022/9786160. 2022
Changes in human skin composition due to intrinsic aging: a histologic and morphometric study.
Arnal-Forne, Marta; (...); Ruiz-Sauri, Amparo
Article. 10.1007/s00418-024-02305-w. 2024
Characterization of hiPSC-CMs derived from pediatric cancer patients treated with anthracyclines that suffered cardiotoxicity
Reinal, I.; (...); Sepulveda, P.
Meeting Abstract. 2021
EVs derived from HIF-overexpressing MSC primed with a pro-inflammatory cocktail promote M2 macrophage polarization and reduce fibrosis and endothelium activation in vitro and in a mouse ulcerous colitis model.
Gomez-Ferrer, M.; (...); Sepulveda, P.
Meeting Abstract. 2021
Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction.
Amaro-Prellezo, Elena; (...); Sepulveda, Pilar
Article. 10.1186/s41232-024-00340-7. 2024
Extracellular Vesicles Secreted by Hypoxic AC10 Cardiomyocytes Modulate Fibroblast Cell Motility.
Ontoria-Oviedo, I; (...); Sepulveda, P
Article. 10.3389/fcvm.2018.00152. 2018
Genotype FBN1/Phenotype relationship in a cohort of patients with Marfan syndrome.
Hernándiz A; (...); Sepúlveda P
Article. 10.1111/cge.13879. 2020
HIF-1 alpha and Pro-Inflammatory Signaling Improves the Immunomodulatory Activity of MSC-Derived Extracellular Vesicles
Gomez-Ferrer, M; (...); Dorronsoro, A
Article. 10.3390/ijms22073416. 2021
HIF-Overexpression and Pro-Inflammatory Priming in Human Mesenchymal Stromal Cells Improves the Healing Properties of Extracellular Vesicles in Experimental Crohn's Disease.
Gómez-Ferrer M; (...); Sepúlveda P
Article. 10.3390/ijms222011269. 2021
Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation.
Gómez-Ferrer M; (...); Sepúlveda P
Article. 10.3389/fimmu.2023.1293737. 2023
In vitro model of atrial fibrillation: investigating the initiation and maintenance mechanisms of atrial remodeling using hiPSC-derived atrial cardiomyocytes
Casini, M.; (...); Sepulveda, P.
Meeting Abstract. 2023
Intracellular role of IL - 6 in mesenchymal stromal cell immunosuppression and proliferation
Dorronsoro, Akaitz; (...); Trigueros C
Article. 2020
Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation.
Dorronsoro, Akaitz; (...); Trigueros, Cesar
Article. 10.1038/s41598-020-78864-4. 2020
Isolation and Lipidomic Screening of Human Milk Extracellular Vesicles.
Ramos-Garcia, Victoria; (...); Kuligowski, Julia
Article. 10.1007/978-1-0716-2699-3_18. 2023
Isolation of extracellular vesicles derived from mesenchymal stem cells by ultracentrifugation and tangential flow filtration followed by size-exclusion chromatography: a functional comparison
Amaro-Prellezo, E.; (...); Sepulveda, P.
Meeting Abstract. 2021
miR-4732-3p in Extracellular Vesicles From Mesenchymal Stromal Cells Is Cardioprotective During Myocardial Ischemia
Sánchez-Sánchez R; (...); Sepúlveda P
Article. 10.3389/fcell.2021.734143. 2021
miRNA-4732-3p as a possible therapeutic tool for the treatment of myocardial ischemia
Sanchez-Sanchez, R.; (...); Sepulveda, P.
Meeting Abstract. 2021
Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs.
Reinal, Ignacio; (...); Sepulveda, Pilar
Article. 10.3390/antiox12071378. 2023
Modeling Transposition of the Great Arteries with Patient-Specific Induced Pluripotent Stem Cells.
Ontoria-Oviedo, Imelda; (...); Sepulveda, Pilar
Article. 10.3390/ijms222413270. 2021
Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds.
Verheijen, Marcha; (...); HeCaToS Consortium
Article. 10.1038/s41597-022-01825-1. 2022
Non-classical Notch signaling by MDA-MB-231 breast cancer cell-derived small extracellular vesicles promotes malignancy in poorly invasive MCF-7 cells.
Gonzalez-King, Hernan; (...); Garcia, Nahuel A.
Article. 10.1038/s41417-021-00411-8. 2022
Normalization approaches for extracellular vesicle-derived lipidomic fingerprints - A human milk case study
Ten-Domenech, Isabel; (...); Kuligowski, Julia
Article. 10.1016/j.chemolab.2024.105070. 2024
Oncostatin M-Enriched Small Extracellular Vesicles Derived from Mesenchymal Stem Cells Prevent Isoproterenol-Induced Fibrosis and Enhance Angiogenesis.
Tejedor, Sandra; (...); Sepulveda, Pilar
Article. 10.3390/ijms24076467. 2023
Optimization of Mesenchymal Stromal Cell (MSC) Manufacturing Processes for a Better Therapeutic Outcome
Fernandez-Santos, Maria Eugenia; (...); Zapata, Agustin G.
Article. 10.3389/fimmu.2022.918565. 2022
Over-Expression of HIF-1A In Mesenchymal Stromal Cells Increases Human CD34+Cells Clonogenic Capacity in Vitro And Engraftment Ability in A Xenotransplantation Model
Preciado, S; (...); Sanchez-Guijo, F
Meeting Abstract. 2021
Oxylipin profile of human milk and human milk-derived extracellular vesicles.
Albiach-Delgado, Abel; (...); Quintas, Guillermo
Article. 10.1016/j.aca.2024.342759. 2024
Pharmacological senolysis reduces doxorubicin-induced cardiotoxicity and improves cardiac function in mice.
Lerida-Viso, Araceli; (...); Martinez-Manez, Ramon
Article. 10.1016/j.phrs.2022.106356. 2022
Plasmatic Membrane Expression of Adhesion Molecules in Human Cardiac Progenitor/Stem Cells Might Explain Their Superior Cell Engraftment after Cell Transplantation.
Ontoria-Oviedo I; (...); Sepúlveda P
Article. 10.1155/2020/8872009. 2020
Platelet rich plasma and plasma rich in growth factors for split-thickness skin graft donor site treatment in the burn patient setting: A randomized clinical trial.
García-Sánchez JM; (...); Pérez-Del-Caz MD
Article. 10.1016/j.burns.2021.10.001. 2021
Polycaprolactone/gelatin-based scaffolds with tailored performance: in vitro and in vivo validation
Gil-Castell, O; (...); Ribes-Greus, A
Article. 10.1016/j.msec.2019.110296. 2020
Polymer Conjugation of Docosahexaenoic Acid Potentiates Cardioprotective Therapy in Preclinical Models of Myocardial Ischemia/Reperfusion Injury.
Tejedor S; (...); Vicent MJ
Article. 10.1002/adhm.202002121. 2021
Priorities in Cardio-Oncology Basic and Translational Science: GCOS 2023 Symposium Proceedings: JACC: CardioOncology State-of-the-Art Review.
Salloum FN; (...); López-Fernández T
Article. 10.1016/j.jaccao.2023.08.003. 2023
Prognostic value and clinical predictors of intramyocardial hemorrhage measured by CMR T2* sequences in STEMI.
Ferré-Vallverdú M; (...); Igual-Muñoz B
Article. 10.1007/s10554-020-02142-7. 2021
Reliable assessment of carbon black nanomaterial of a variety of cell culture media for in vitro toxicity assays by asymmetrical flow field-flow fractionation.
Boughbina-Portoles, Aaron; (...); Campins-Falco, Pilar
Article. 10.1007/s00216-023-04597-8. 2023
Subtype-specific differentiation of atrial and ventricular cardiomyocytes from human iPSCs
Casini, M.; (...); Sepulveda, P.
Meeting Abstract. 2021
The Vascular Niche for Adult Cardiac Progenitor Cells.
Herrero, Diego; (...); Bernad, Antonio
Article. 10.3390/antiox11050882. 2022
Topical Administration of a Marine Oil Rich in Pro-Resolving Lipid Mediators Accelerates Wound Healing in Diabetic db/db Mice through Angiogenesis and Macrophage Polarization.
Ontoria-Oviedo, Imelda; (...); Sepulveda, Pilar
Article. 10.3390/ijms23179918. 2022
Two-component Peptidic Molecular Gels for Topical Drug Delivery of Naproxen
Martí-Centelles, Rosa; (...); Escuder, Beatriu
Article. 10.1021/acsabm.0c01422. 2021
Use of an electrospun bioveil is safe and does not decrease skin graft take on burn wounds: A randomised, controlled clinical trial.
Perez-Del-Caz, Maria Dolores; (...); Perez-Plaza, Aranzazu
Article. 10.1016/j.burns.2025.107427. 2025