FUNCIÓN DE ATM EN NEUROBLASTOMAS DE ALTO RIESGO CON DELECIÓN EN 11Q: UNA INNOVADORA APROXIMACIÓN

Dades bàsiques

Codi Financador:
2016_0002_CRC_AECC_FONT_DE_MORA
Any inicial:
2016
Any final:
2019
PROYECTO NACIONAL Finan. Competitiva Privada 36.000,00 €

Objectius del projecte

El periodo de seguimiento final para la realización de la justificación económica y científica se abrirá el 26 de diciembre hasta el 26 de febrero

Documents

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Participants

Grups d'Investigació

Finançadors

FUNDACIÓN CIENTÍFICA AECC

Resultats del Projecte


Advances in emerging drugs for the treatment of neuroblastoma

Berlanga, P, Cañete A, Castela, V

Review. 10.1080/14728214.2017.1294159. 2017


Assessment of the dicentric chromosome assay as a biodosimetry tool for more personalized medicine in a case of a high risk neuroblastoma I-131-mIBG treatment

Chimeno, JM; (...); Montoro, A

Article. 10.1080/09553002.2019.1549755. 2018


Barriers and facilitators to implementation of the interoperable Survivorship Passport (SurPass) v2.0 in 6 European countries: a PanCareSurPass online survey study.

van den Oever, Selina R; (...); Pluijm, Saskia M F

Article. 10.1007/s11764-023-01335-y. 2023

  • Open Access.

Barriers and facilitators to the implementation of a new European eHealth solution (SurPass v2.0): the PanCareSurPass Open Space study.

de Beijer IAE; (...); Pluijm SMF

Article. 10.1007/s11764-023-01498-8. 2023

  • Open Access.

Can We Identify Chemotherapy-Related Toxicity in Children with Cancer Through Automatized Integration of Healthcare Information Systems?

Berlanga, P; (...); Canete, A

Meeting Abstract. 2017


Clinical experience of whole body and tumour dosimetry of 131-I-mIBG treatment for pediatric patients

Espallardo, I. Torres; (...); Prado-Wohlwend, S.

Meeting Abstract. 2023


Clinical Features of Neuroblastoma With 11q Deletion: An Increase in Relapse Probabilities In Localized And 4S Stages.

J Ribelles A; (...); Castel V

Article. 10.1038/s41598-019-50327-5. 2019

  • Open Access.

Correction: Barriers and facilitators to the implementation of a new European eHealth solution (SurPass v2.0): the PanCareSurPass Open Space study.

de Beijer IAE; (...); Pluijm SMF

Correction. 10.1007/s11764-024-01547-w. 2024

  • Open Access.

Deletion of 11q in Neuroblastomas Drives Sensitivity to PARP Inhibition

Sanmartin, E; (...); Font de Mora J

Article. 10.1158/1078-0432.CCR-17-0593. 2017

  • Open Access.

Distribution of segmental chromosomal alterations in neuroblastoma.

Juan Ribelles A; (...); Castel V

Article. 10.1007/s12094-020-02497-2. 2020


Early clinical trials in paediatric oncology in Spain: a nationwide perspective

Bautista, F; (...); Sociedad Española de Hematología y Oncología Pediátrica (SEHOP) and the New Drug

Article. 10.1016/j.anpedi.2016.07.007. 2017

  • Open Access.

El nuevo reto en oncologia: la secuenciacion NGS y su aplicacion a la medicina de precision.

Calabria I; (...); Castel V

Article. 10.1016/j.anpedi.2016.05.006. 2016


Epigenetics and Oxidative Stress in Aging

Guillaumet-Adkins, A; (...); Sandoval, J

Review. 10.1155/2017/9175806. 2017

  • Open Access.

Evaluation of circulating tumor DNA by electropherogram analysis and methylome profiling in high-risk neuroblastomas

Trinidad, Eva Maria; (...); de Mora, Jaime Font

Article. 10.3389/fonc.2023.1037342. 2023

  • Open Access.

Event-free survival of infants and toddlers enrolled in the HR-NBL-1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis

Corrias, MV; (...); Burchill, SA

Article. 10.1002/pbc.27052. 2018

  • Open Access.

Exosomal microRNAs from Longitudinal Liquid Biopsies for the Prediction of Response to Induction Chemotherapy in High-Risk Neuroblastoma Patients: A Proof of Concept SIOPEN Study.

Morini M; (...); Varesio L

Article. 10.3390/cancers11101476. 2019

  • Open Access.

Free flaps as a first option for reconstruction of shoulder girdle high recurrence risk tumors.

Pérez-García A; (...); Baixauli F

Letter. 10.1002/jso.26064. 2020


Frequency and Prognostic Impact of ALK Amplifications and Mutations in the European Neuroblastoma Study Group (SIOPEN) High-Risk Neuroblastoma Trial (HR-NBL1).

Bellini, Angela; (...); Schleiermacher, Gudrun

Article. 10.1200/JCO.21.00086. 2021

  • Open Access.

Germline Predisposition to Pediatric Cancer, from Next Generation Sequencing to Medical Care.

Gargallo P; (...); Cañete A

Article. 10.3390/cancers13215339. 2021

  • Open Access.

Germline variant in Ctcf links mental retardation to Wilms tumor predisposition

Gargallo, Pablo; (...); Font de Mora, Jaime

Article. 10.1038/s41431-022-01105-x. 2022


Global Retinoblastoma Presentation and Analysis by National Income Level.

Global Retinoblastoma Study Group; (...); Bowman R

Article. 10.1001/jamaoncol.2019.6716. 2020

  • Open Access.

Identification Of Actionable Genetic Targets In Primary Cardiac Sarcomas

Salvador-Coloma, C; (...); de Mora, JF

Article. 10.2147/OTT.S214319. 2019

  • Open Access.

Immunosuppressive profiles in liquid biopsy at diagnosis predict response to neoadjuvant chemotherapy in triple-negative breast cancer

Salvador-Coloma, C; (...); de Mora, JF

Article. 10.1016/j.ejca.2020.08.020. 2020

  • Open Access.

Immunosuppressive profiles in liquid biopsy predict response to neoadjuvant chemotherapy in triple negative breast cancer

Salvador-Coloma, C; (...); Santaballa, A

Meeting Abstract. 10.1158/1538-7445.SABCS18-P3-11-16. 2019


Intratumoral immunosuppression profiles in 11q-deleted neuroblastomas provide new potential therapeutic targets.

Coronado, Esther; (...); Font de Mora, Jaime

Article. 10.1002/1878-0261.12868. 2021

  • Open Access.

Intravitreal melphalan therapy for vitreous seeds in retinoblastoma: Implementation and outcomes of a new chemotherapy protocol.

Solana-Altabella A; (...); Poveda JL

Article. 10.1177/1078155220904410. 2020


IT-Related Barriers and Facilitators to the Implementation of a New European eHealth Solution, the Digital Survivorship Passport (SurPass Version 2.0): Semistructured Digital Survey.

de Beijer, Ismay A E; (...); Chronaki, Catherine

Article. 10.2196/49910. 2024

  • Open Access.

Li-Fraumeni syndrome heterogeneity.

Gargallo P; (...); Cañete A

Review. 10.1007/s12094-019-02236-2. 2020


Li-Fraumeni: Will the detection in families increase the survival of its members?

Gargallo, P; (...); Canete, A

Letter. 10.1016/j.anpedi.2018.03.009. 2019

  • Open Access.

Liquid Biopsies of Patients with HIGH-RISK Neuroblastoma Disclose Exosomal miRNA Modulation after the Induction Therapy

Morini, M; (...); Varesio, L

Meeting Abstract. 2017


Liquid Biopsies Provide Exosomal MicroRNAs as Biomarkers of the Response to Induction Chemotherapy in High-Risk Neuroblastoma Patients

Morini, M; (...); Varesio, L

Meeting Abstract. 2018


Liquid Biopsy Micro-RNA Profiling in Meduloblastoma

Yanez, Y; (...); Canete, A

Meeting Abstract. 2018


Liquidhope: methylome and genomic profiling from very limited quantities of plasma-derived DNA.

Trinidad EM; (...); Font de Mora J

Article. 10.1093/bib/bbac575. 2023

  • Open Access.

Medulloblastoma: improved survival in recent decades. Unicentric experience

Igual Estellés L, Berlanga Charriel P, Cañete Nieto A

Article. 10.1016/j.anpedi.2016.03.004. 2017


Metabolomic profiling in neuroblastoma.

Quintás G; (...); Segura V

Article. 10.1002/pbc.28113. 2020


Metastatic neuroblastoma in infants: are survival rates excellent only within the stringent framework of clinical trials?

Di Cataldo, A; (...); Canete, A

Article. 10.1007/s12094-016-1505-1. 2017


Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs.

Reinal, Ignacio; (...); Sepulveda, Pilar

Article. 10.3390/antiox12071378. 2023

  • Open Access.

MTHFR and VDR Polymorphisms Improve the Prognostic Value of MYCN Status on Overall Survival in Neuroblastoma Patients

Olivera, GG; (...); Herrero, MJ

Article. 10.3390/ijms21082714. 2020

  • Open Access.

Multi-parametric MR Imaging Biomarkers Associated to Clinical Outcomes in Gliomas: A Systematic Review.

Oltra-Sastre M; (...); Garcia-Gomez JM

Article. 10.2174/1573405615666190109100503. 2019

  • Open Access.

Nefroblastoma. Experiencia a largo plazo en el abordaje multidisciplinario.

Rodriguez Iglesias P; (...); Boronat Tormo F

Abstract of Published Item. 2018


Next-Generation Sequencing Identifies Potential Actionable Targets in Paediatric Sarcomas

Ribelles, AJ; (...); Canete, A

Article. 10.3390/jpm11040268. 2021

  • Open Access.

Outcomes of BRAF V600E Pediatric Gliomas Treated With Targeted BRAF Inhibition.

Nobre L; (...); Tabori U

Article. 10.1200/PO.19.00298. 2020

  • Open Access.

Pattern and predictors of sites of relapse in neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project.

Vo, Kieuhoa T.; (...); Matthay, Katherine K.

Article. 10.1002/pbc.29616. 2022


Personalized Medicine in Infant Population with Cancer: Pharmacogenetic Pilot Study of Polymorphisms Related to Toxicity and Response to Chemotherapy.

Urtasun, Andrea; (...); Herrero, Maria Jose

Article. 10.3390/cancers15051424. 2023

  • Open Access.

Personalized Medicine: Learning to Walk

Gargallo, P.; (...); Canete, A.

Meeting Abstract. 2018


PHARMACOGENETIC VARIANTS ASSOCIATED WITH TREATMENT RESPONSE IN NEUROBLASTOMA

Olivera, G; (...); Alino, SF

Meeting Abstract. 2018


Pharmacogenetics implementation in the clinics: information and guidelines for germline variants

Olivera, Gladys; (...); Alino, Salvador F.

Review. 10.20517/cdr.2018.25. 2019

  • Open Access.

Pharmacogenetics in Neuroblastoma: What Can Already Be Clinically Implemented and What Is Coming Next?

Olivera, GG; (...); Herrero, MJ

Review. 10.3390/ijms22189815. 2021

  • Open Access.

Plasma Metabolomic Profiling Differentiates High- and Low-Risk Neuroblastoma Patients

Quintas, G; (...); Segura, V

Meeting Abstract. 2018


Precision medicine in Ewing sarcoma: a translational point of view.

Gargallo P; (...); Cañete A

Review. 10.1007/s12094-020-02298-7. 2020


Preliminarily results of the Oncohabitats Study: A multicentre validation of overall survival (OS) estimation of patients with glioblastoma (GBM) using vascular biomarkers

Alvarez-Torres, MD; (...); Garcia-Gomez, JM

Meeting Abstract. 10.1158/1538-7445.AM2019-4258. 2019


Publisher Correction: Clinical Features of Neuroblastoma With 11q Deletion: An Increase in Relapse Probabilities In Localized And 4S Stages.

Juan Ribelles A; (...); Castel V

Correction. 10.1038/s41598-020-58428-2. 2020

  • Open Access.

Response rate in cardiac resynchronization therapy patients implanted with a left ventricular quadripolar lead and the MultiPoint(TM) Pacing feature activated. QUARTO III.

Osca, Joaquin; (...); Alzueta, Javier

Article. 10.1111/eci.13935. 2022


Retinoblastoma and mosaic 13q deletion: a case report

Gargallo P; (...); Canete, A

Article. 10.1186/s40942-021-00321-9. 2021

  • Open Access.

Retinoblastoma: towards an earlier diagnosis.

Gargallo P; (...); Cañete A

Article. 10.1016/j.oftal.2018.05.003. 2018


Review: Ewing Sarcoma Predisposition.

Gargallo P; (...); Cañete A

Article. 10.1007/s12253-019-00765-3. 2019


Robust association between vascular habitats and patient prognosis in glioblastoma: An international multicenter study.

Álvarez-Torres MDM; (...); García-Gómez JM

Article. 10.1002/jmri.26958. 2020

  • Open Access.

Spinal cord compression syndrome in pediatric oncology: review of a series of cases in a tertiary level center.

Sánchez HM, Guill JB, Zúñiga RV

Case Reports. 10.1016/j.anpede.2024.01.008. 2024

  • Open Access.

Spinal cord compression syndrome in pediatric oncology: Review of a series of cases in a tertiary level center

Sanchez, Helena Martinez, Guill, Julia Balaguer, Zuniga, Roberto Velasco

Letter. 10.1016/j.anpedi.2023.09.013. 2024

  • Open Access.

Successful Second-Line Metronomic Temozolomide in Metastatic Paraganglioma: Case Reports and Review of the Literature.

Tena, I; (...); Pacak, K

Article. 10.1177/1179554918763367. 2018

  • Open Access.

Survey on paediatric tumour boards in Europe: current situation and results from the ExPo-r-Net project

Juan Ribelles A; (...); Ladenstein, R

Article. 10.1007/s12094-017-1820-1. 2018


The Embryonic Key Pluripotent Factor NANOG Mediates Glioblastoma Cell Migration via the SDF1/CXCR4 Pathway.

Sanchez-Sanchez, Ana Virginia; (...); Mullor, Jose Luis

Article. 10.3390/ijms221910620. 2021

  • Open Access.

The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries

Alia, Donjeta B.; (...); Nyaywa, Mutale

Article. 10.1016/S2214-109X(22)00250-9. 2022

  • Open Access.

TIAM1 variants improve clinical outcome in neuroblastoma

Sanmartin, E; (...); Font de Mora J

Article. 10.18632/oncotarget.16787. 2017

  • Open Access.

Travel burden and clinical presentation of retinoblastoma: analysis of 1024 patients from 43 African countries and 518 patients from 40 European countries.

Fabian, Ido Didi; (...); Bowman, Richard

Article. 10.1136/bjophthalmol-2020-316613. 2020

  • Open Access.

Tumour growth: An approach to calibrate parameters of a multiphase porous media model based on in vitro observations of Neuroblastoma spheroid growth in a hydrogel microenvironment.

Hervas-Raluy, Silvia; (...); Wall, Wolfgang A.

Article. 10.1016/j.compbiomed.2023.106895. 2023

  • Open Access.

Untitled

Castel, V; (...); Zuniga, A

Letter. 10.1007/s12094-018-1889-1. 2018


Upregulation of sFRP3 circulating expression levels correlates survival outcomes in glioblastoma

Bruixola, G; (...); Reynes, G

Meeting Abstract. 2019


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