Portal de investigación
UNA APROXIMACIÓN ÓMICA AL DIAGNÓSTICO DE LA TUBERCULOSIS
Datos básicos
- NumeroConcesion:
- PCIN-2013-041
- Año inicial:
- 2015
- Año final:
- 2016
Objetivos del proyecto
CONCEDIDO
Documentos
- No hay documentos
Participantes
Financiadores
Resultados del Proyecto
A Drosophila model of GDAP1 function reveals the involvement of insulin signalling in the mitochondria-dependent neuromuscular degeneration
López Del Amo V; (...); Galindo, MI
Article. 10.1016/j.bbadis.2017.01.003. 2017
A surface plasmon resonance based approach for measuring response to pneumococcal vaccine.
Garrido-Jareño M; (...); Pineda-Lucena A
Article. 10.1038/s41598-021-85958-0. 2021
A translational approach to assess the metabolomic impact of stabilized gold nanoparticles by NMR spectroscopy
Herance, JR; (...); Palomino-Schatzlein, M
Article. 10.1039/c8an01827h. 2019
Active and prospective latent tuberculosis are associated with different metabolomic profiles: clinical potential for the identification of rapid and non-invasive biomarkers.
Albors-Vaquer A; (...); Puchades-Carrasco L
Article. 10.1080/22221751.2020.1760734. 2020
Assessment of gold nanoparticles on human peripheral blood cells by metabolic profiling with H-1-NMR spectroscopy, a novel translational approach on a patient-specific basis
Palomino-Schatzlein, M; (...); Herance, JAR
Article. 10.1371/journal.pone.0182985. 2017
Bioinformatics tools for the analysis of NMR metabolomics studies focused on the identification of clinically relevant biomarkers
Puchades-Carrasco L; (...); Pineda-Lucena A
Article. 10.1093/bib/bbv077. 2016
Body-fat sensor triggers ribosome maturation in the steroidogenic gland to initiate sexual maturation in Drosophila.
Juarez-Carreno, Sergio; (...); Morante, Javier
Article. 10.1016/j.celrep.2021.109830. 2021
Corrigendum to A Drosophila model of GDAP1 function reveals the involvement of insulin signalling in the mitochondria-dependent neuromuscular degeneration [Biochim. Biophys. Acta 1863 (2017) 801-809].
López Del Amo V; (...); Galindo MI
Article. 10.1016/j.bbadis.2018.11.001. 2019
Characterization of anaphylaxis reveals different metabolic changes depending on severity and triggers
Perales-Chorda C; (...); de Rojas, DHF
Article. 10.1111/cea.13991. 2021
Development of inhibitors of receptor protein tyrosine phosphatase beta/zeta (PTPRZ1) as candidates for CNS disorders
Pastor, M; (...); Ramos, A
Article. 10.1016/j.ejmech.2017.11.080. 2018
Discovery and preclinical development of a SdAb-based CAR-T technology for targeting CD33 in AML
Bernasconi-Bisio, Franco; (...); Pineda-Lucena, Antonio
Article. 10.1016/j.omton.2025.200949. 2025
Discovery of serum biomarkers for diagnosis of tuberculosis by NMR metabolomics including cross-validation with a second cohort.
Conde R; (...); Coelho AV
Article. 10.1016/j.bj.2021.07.006. 2021
EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
Brennecke, P; (...); Gribbon, P
Article. 10.1177/2472555218816276. 2019
Fragment Binding to beta-Secretase 1 without Catalytic Aspartate Interactions Identified via Orthogonal Screening Approaches
Rombouts, FJR; (...); Tresadern, G
Article. 10.1021/acsomega.6b00482. 2017
G9a/DNMT1 co-targeting inhibits non-small cell lung cancer growth and reprograms tumor cells to respond to cancer-drugs through SCARA5 and AOX1.
Exposito, Francisco; (...); Calvo, Alfonso
Article. 10.1038/s41419-024-07156-w. 2024
Glutamine/glutamate metabolism rewiring in reprogrammed human hepatocyte-like cells
Ballester, M; (...); Bort, R
Article. 10.1038/s41598-019-54357-x. 2019
Metabolic Alterations in a Drosophila Model of Parkinson's Disease Based on DJ-1 Deficiency.
Solana-Manrique, Cristina; (...); Paricio, Nuria
Article. 10.3390/cells11030331. 2022
Metabolic fingerprint of insulin resistance in human polymorphonuclear leucocytes
Palomino-Schatzlein, M; (...); Herance, JR
Article. 10.1371/journal.pone.0199351. 2018
Metabolic footprint of aging and obesity in red blood cells.
Domingo-Ortí I; (...); Pineda-Lucena A
Article. 10.18632/aging.202693. 2021
Metabolomic Applications to the Characterization of the Mode-of-Action of CDK Inhibitors.
Palomino-Schätzlein M, Pineda-Lucena A
Article. 10.1007/978-1-4939-2926-9_16. 2016
Metabolomics Applications in Precision Medicine: An Oncological Perspective
Puchades-Carrasco, L, Pineda-Lucena, A
Review. 10.2174/1568026617666170707120034. 2017
Metabolomics Contributions to the Discovery of Prostate Cancer Biomarkers
Gomez-Cebrian, N; (...); Puchades-Carrasco, L
Review. 10.3390/metabo9030048. 2019
Metabolomics facilitates the discrimination of the specific and-cancer effects of free and polymer conjugated doxorubicin in breast cancer models
Arminan, A; (...); Pineda-Lucena, A
Article. 10.1016/j.biomaterials.2018.02.015. 2018
Mobilisation Mechanism of Pathogenicity Islands by Endogenous Phages in Staphylococcus aureus clinical strains.
Cervera-Alamar, M; (...); Tormo-Mas, MA
Article. 10.1038/s41598-018-34918-2. 2018
Multibody cofactor and substrate molecular recognition in the myo-inositol monophosphatase enzyme
Ferruz N; (...); De Fabritiis G
Article. 10.1038/srep30275. 2016
MYC Induces a Hybrid Energetics Program Early in Cell Reprogramming
Prieto, J; (...); Torres, J
Article. 10.1016/j.stemcr.2018.10.018. 2018
NMR-Based Mitochondria Metabolomic Profiling: A New Approach To Reveal Cancer-Associated Alterations.
Domingo-Orti, Ines; (...); Palomino-Schaetzlein, Martina
Article. 10.1021/acs.analchem.3c02432. 2023
Non-invasive urinary metabolomic profiling discriminates prostate cancer from benign prostatic hyperplasia
Perez-Rambla, C; (...); Pineda-Lucena, A
Article. 10.1007/s11306-017-1194-y. 2017
Non-invasive urinary metabolomic profiling discriminates prostate cancer from benign prostatic hyperplasia (vol 13, 52, 2017)
Perez-Rambla, C; (...); Pineda-Lucena, A
Correction. 10.1007/s11306-017-1238-3. 2017
Nuclear magnetic resonance metabolomic profiling of urine provides a noninvasive alternative to the identification of biomarkers associated with endometriosis
Vicente-Muñoz S; (...); Pineda-Lucena A
Article. 10.1016/j.fertnstert.2015.07.1149. 2015
Omics-Based Approaches for the Characterization of Pompe Disease Metabolic Phenotypes
Gomez-Cebrian, Nuria; (...); Puchades-Carrasco, Leonor
Review. 10.3390/biology12091159. 2023
Pathophysiologic processes have an impact on the plasma metabolomic signature of endometriosis patients
Vicente-Munoz, S; (...); Pineda-Lucena, A
Article. 10.1016/j.fertnstert.2016.09.014. 2016
Phenotypic and genotypic characterization of drug-induced liver injury (DILI) with autoimmune features
Stephens, C.; (...); Andrade, Raul J.
Article. 2015
Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach
Urman, JM; (...); Avila, MA
Article. 10.3390/cancers12061644. 2020
Polycythemia Vera and Essential Thrombocythemia Patients Exhibit Unique Serum Metabolic Profiles Compared to Healthy Individuals and Secondary Thrombocytosis Patients.
Gómez-Cebrián N; (...); Puchades-Carrasco L
Article. 10.3390/cancers13030482. 2021
Profiling human blood serum metabolites by nuclear magnetic resonance spectroscopy: a comprehensive tool for the evaluation of hemodialysis efficiency
Kromke M; (...); Muhle-Goll C
Article. 10.1016/j.trsl.2016.02.003. 2016
Rapid two-dimensional ALSOFAST-HSQC experiment for metabolomics and fluxomics studies: application to a C-13-enriched cancer cell model treated with gold nanoparticles
Schatzlein, MP; (...); Luy, B
Article. 10.1007/s00216-018-0961-6. 2018
Recommendations for the integral diagnosis of chronic viral hepatitis in a single analytical extraction.
Crespo, Javier; (...); Calleja, Jose Luis
Practice Guideline. 10.1016/j.gastrohep.2022.09.009. 2023
Serum metabolomic profiling facilitates the non-invasive identification of metabolic biomarkers associated with the onset and progression of non-small cell lung cancer
Puchades-Carrasco L; (...); Pineda-Lucena A
Article. 10.18632/oncotarget.7354. 2016
Small Molecule Inhibition of ERK Dimerization Prevents Tumorigenesis by RAS-ERK Pathway Oncogenes
Herrero A; (...); Crespo P
Article. 10.1016/j.ccell.2015.07.001. 2015
Structural understanding of nitrogen signaling in cyanobacteria via global nitrogen regulator NtcA and protein PipX
Forcada-Nadal, A; (...); Rubio, V
Meeting Abstract. 2018
Study of pediatric invasive pneumococcal disease in the 13-pneumococcal conjugated vaccine era.
Garrido-Jareno, Marta; (...); Peman, Javier
Article. 10.1016/j.diagmicrobio.2024.116532. 2024
Targeted Metabolomics Analyses Reveal Specific Metabolic Alterations in High-Grade Prostate Cancer Patients
Gomez-Cebrian, N; (...); Puchades-Carrasco, L
Article. 10.1021/acs.jproteome.0c00493. 2020
The PipX Protein, When Not Bound to Its Targets, Has Its Signaling C-Terminal Helix in a Flexed Conformation
Forcada-Nadal, A; (...); Rubio, V
Article. 10.1021/acs.biochem.7b00230. 2017
The Pre-treatment Gut Microbiome is Associated with Lack of Response to Methotrexate in New Onset Rheumatoid Arthritis.
Artacho, Alejandro; (...); Scher, Jose U
Article. 10.1002/art.41622. 2020
THE PRE-TREATMENT GUT MICROBIOME PREDICTS EARLY RESPONSE TO RHEUMATOID ARTHRITIS THERAPY
Isaac, S; (...); Scher, J
Meeting Abstract. 10.1136/annrheumdis-2019-eular.8378. 2019
The value of serum aspartate aminotransferase and gamma-glutamyl transpetidase as biomarkers in hepatotoxicity
Robles-Diaz M; (...); Faster Evidence-based Translation (SAFE-T) Consortium
Article. 10.1111/liv.12834. 2015
Vaginal metabolome: towards a minimally invasive diagnosis of microbial invasion of the amniotic cavity in women with preterm labor
Vicente-Munoz, S; (...); Gratacos, E
Article. 10.1038/s41598-020-62542-6. 2020
Campos de Estudio
Cita
UNA APROXIMACIÓN ÓMICA AL DIAGNÓSTICO DE LA TUBERCULOSIS. (PCIN-2013-041). FUNDACIÓN PARA LA INVESTIGACIÓN DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA; MINISTERIO DE ECONOMIA Y COMPETITIVIDAD. 2015-2016.