The transcriptome analysis of Strongyloides stercoralis L3i larvae reveals targets for intervention in a neglected disease.

Autores de IIS La Fe

• Antonio Marcilla Díaz

  Autor

• Jose Sotillo Marti

  Autor

• María Trelis Villanueva

  Autor

Participantes ajenos a IIS La Fe

• Garg G
• Bernal D
• Ranganathan S
• Forment J
• Ortiz J
• Muñoz-Antolí C
• Dominguez MV
• Pedrola L
• Martinez-Blanch J
• Toledo R
• Esteban JG

Abstract

Strongyloidiasis is one of the most neglected diseases distributed worldwide with endemic areas in developed countries, where chronic infections are life threatening. Despite its impact, very little is known about the molecular biology of the parasite involved and its interplay with its hosts. Next generation sequencing technologies now provide unique opportunities to rapidly address these questions.